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<channel>
	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/14215?offset=950</link>
	<atom:link href="https://bioinformaticsonline.com/related/14215?offset=950" rel="self" type="application/rss+xml" />
	<description><![CDATA[]]></description>
	
	
<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/29883/ra-bioinformatics-at-school-of-computational-integrative-sciences-jnu-india</guid>
  <pubDate>Fri, 18 Nov 2016 03:57:56 -0600</pubDate>
  <link></link>
  <title><![CDATA[RA Bioinformatics at School of Computational &amp; Integrative Sciences, JNU, India]]></title>
  <description><![CDATA[
<p>School of Computational &amp; Integrative Sciences<br />Jawaharlal Nehru University<br />New Delhi – 110067</p>

<p>Date: Nov 11th. 2016                                                            Last Date:  Nov 25th. 2016</p>

<p>PROJECT ID: 632</p>

<p>The following posts are urgently required to be filled for the Department of Biotechnology, Government of India funded project entitled "Computational Core for Plant Metabolomics" administrated by Prof Indira Ghosh,  School of Computational and Integrative Sciences, Jawaharlal Nehru University, New Delhi-110 067</p>

<p>NB:For all Bioinformatics posts, preference will be given to candidates with a good knowledge of Python and/or R. Knowledge of JAVA will also get a special consideration.</p>

<p>RA / Research Associate (Metabolic engineering/Computational Biologist)</p>

<p>Salary: Rs. 36000/- + HRA<br />Vacancy: 1<br />Essential Qualifications: PhD in  Bioinformatics /Mathematics/Computer Science with experience in analyzing high throughput omics-based data/ system Biology/ Analysis of Network Biology. Published paper in the field is a must to prove the experience.<br />Desired Skills: Prior experience in handling and guiding bioinformatics, metabolomics data, planning of new research area in metabolic driven network , managing the project portal, preparing and filing reports etc. Will be expected to communicate with user groups and coordinate with LIMS group in Hyderabad and the Cheminformatics group in Delhi.</p>

<p>RA / Research Associate (Chemo-informatics/Computational Biologist)</p>

<p>Salary: Rs. 36000/- + HRA<br />Vacancy: 1<br />Essential Qualifications: PhD in Bioinformatics/ computational biology/ Biophysics/Computer Science. Computational and Chemical structure related experience is a necessary qualification proven by paper published and program developed. <br />Desired Skills:  Research experience in Chemical scaffold mapping, in silico Spectral analysis, Biological Database Designing &amp; Integration is required. Individual is responsible to develop methods related to metabolite identification, Testing and refining and integrate LIMS with IIIT Hyderabad and will be expected to communicate with user groups.</p>

<p>Project SRF (Bioinformatics/Programming)</p>

<p>Salary: As per DBT rules<br />Vacancy: 1<br />Essential Qualifications: Masters/B Tech in Basic Sciences with at least 2yrs of research experience in Bioinformatics/Computational Biology related to Database /portal building &amp; maintenance ,high throughput data handling and analysis etc. For M.Sc/B.Tec, Published paper  in peer-reviewed Journal and for M.Tech, thesis submission in computational biology is a must.</p>

<p>More at http://www.jnu.ac.in/Career/currentjobs.htm</p>
]]></description>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/29917/gojs</guid>
	<pubDate>Tue, 22 Nov 2016 08:25:37 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/29917/gojs</link>
	<title><![CDATA[GoJS]]></title>
	<description><![CDATA[<p><strong>GoJS</strong> is a feature-rich JavaScript library for implementing custom interactive diagrams and complex visualizations across modern web browsers and platforms. <strong>GoJS</strong> makes constructing JavaScript diagrams of complex nodes, links, and groups easy with customizable templates and layouts.</p>
<p><strong>GoJS</strong> offers many advanced features for user interactivity such as drag-and-drop, copy-and-paste, in-place text editing, tooltips, context menus, automatic layouts, templates, data binding and models, transactional state and undo management, palettes, overviews, event handlers, commands, and an extensible tool system for custom operations.</p>
<p><strong>GoJS</strong> is pure JavaScript, so users get interactivity without requiring round-trips to servers and without plugins. <strong>GoJS</strong> normally runs completely in the browser, rendering to an HTML5 Canvas element or SVG without any server-side requirements. <strong>GoJS</strong> does not depend on any JavaScript libraries or frameworks, so it should work with any HTML or JavaScript framework or with no framework at all. &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;</p>
<p>More at&nbsp;http://gojs.net/latest/index.html</p><p>Address of the bookmark: <a href="http://gojs.net/latest/index.html" rel="nofollow">http://gojs.net/latest/index.html</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/30002/excavator2tool</guid>
	<pubDate>Wed, 30 Nov 2016 04:09:19 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/30002/excavator2tool</link>
	<title><![CDATA[EXCAVATOR2tool]]></title>
	<description><![CDATA[<p><span>EXCAVATOR2 is a collection of bash, R and Fortran scripts and codes that analyses Whole Exome Sequencing (WES) data to identify CNVs. EXCAVATOR2 enhances the identification of all genomic CNVs, both overlapping and non-overlapping targeted exons by integrating the analysis of In-targets and Off- targets reads. Specifically, it improves the precision of calling CNVs overlapping targeted exons from WES data and enlarges the spectrum of detectable CNVs to off-target events.</span><br><span>EXCAVATOR2 can be effectively employed for the identification of CNVs in small as well as large-scale re-sequencing population and cancer studies. Lastly, it&rsquo;s of particular interest that all WES experiments can be re-analysed using our method with the beneficial effect to identify novelCNVs in extra-exonic regions by having the full-genome CN profile.</span></p><p>Address of the bookmark: <a href="https://sourceforge.net/projects/excavator2tool/" rel="nofollow">https://sourceforge.net/projects/excavator2tool/</a></p>]]></description>
	<dc:creator>Bulbul</dc:creator>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/30198/faculty-at-indian-institute-of-science-education-and-research-berhampur</guid>
  <pubDate>Mon, 19 Dec 2016 03:34:26 -0600</pubDate>
  <link></link>
  <title><![CDATA[Faculty at Indian Institute of Science Education and Research Berhampur]]></title>
  <description><![CDATA[
<p>Advt. No: IISERBPR/DoFA/2016/2</p>

<p>Advertisement for Faculty Positions</p>

<p>The IISER Berhampur, an Institute of national importance, established through an act of Parliament is an autonomous organization under the Ministry of HRD, Govt. of India, to promote quality education and cutting edge research in basic sciences and to provide a platform for the faculty to engage in high quality education, at undergraduate and postgraduate levels. The Institute invites applications for faculty positions at the level of Assistant Professor (C) /Assistant Professor in the following disciplines:</p>

<p>1. Biological Sciences</p>

<p>2. Chemistry</p>

<p>3. Computer Sciences</p>

<p>4. Mathematics</p>

<p>5. Physics</p>

<p>Only hard copy of application in the prescribed format, via Speed Post should be sent to the Dean, Faculty Affairs, IISER Berhampur, Industrial Training Institute (ITI) Berhampur, Engineering School Road, Berhampur - 760 010, Ganjam District, Odisha, before 1700 hrs., December 30, 2016.</p>

<p>http://www.iiserbpr.ac.in</p>

<p>More Info : http://www.iiserbpr.ac.in/vacancies/Advertisement%20for%20Faculty%20Positions%20at%20IISER%20Berhampur.pdf</p>
]]></description>
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<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/30355/meme-suite</guid>
	<pubDate>Fri, 23 Dec 2016 08:49:55 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/30355/meme-suite</link>
	<title><![CDATA[MEME suite]]></title>
	<description><![CDATA[<p>Motif based sequence analysis suits&nbsp;</p>
<p>The MEME Suite allows the biologist to discover novel motifs in collections of unaligned nucleotide or protein sequences, and to perform a wide variety of other motif-based analyses.</p>
<p>The MEME Suite supports motif-based analysis of DNA, RNA and protein sequences. It provides motif discovery algorithms using both probabilistic (MEME) and discrete models (MEME), which have complementary strengths. It also allows discovery of motifs with arbitrary insertions and deletions (GLAM2). In addition to motif discovery, the MEME Suite provides tools for scanning sequences for matches to motifs (FIMO, MAST and GLAM2Scan), scanning for clusters of motifs (MCAST), comparing motifs to known motifs (Tomtom), finding preferred spacings between motifs (SpaMo), predicting the biological roles of motifs (GOMo), measuring the positional enrichment of sequences for known motifs (CentriMo), and analyzing ChIP-seq and other large datasets (MEME-ChIP).</p>
<p>The MEME Suite is comprised of a collection of tools that work together, as shown below. Not all the tools are available as webservices, so to get the full power of the MEME Suite you will need to&nbsp;<a href="http://meme-suite.org/doc/download.html">download</a>&nbsp;and&nbsp;<a href="http://meme-suite.org/doc/install.html">install</a>&nbsp;a local copy of the software. To see what has changed recently you can peruse the&nbsp;<a href="http://meme-suite.org/doc/release-notes.html">release notes</a>.</p>
<p>http://meme-suite.org/</p><p>Address of the bookmark: <a href="http://meme-suite.org/" rel="nofollow">http://meme-suite.org/</a></p>]]></description>
	<dc:creator>Bulbul</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/30555/yaha</guid>
	<pubDate>Fri, 20 Jan 2017 05:38:05 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/30555/yaha</link>
	<title><![CDATA[YAHA]]></title>
	<description><![CDATA[<p>YAHA, a fast and flexible hash-based aligner. YAHA is as fast and accurate as BWA-SW at finding the single best alignment per query and is dramatically faster and more sensitive than both SSAHA2 and MegaBLAST at finding all possible alignments. Unlike other aligners that report all, or one, alignment per query, or that use simple heuristics to select alignments, YAHA uses a directed acyclic graph to find the optimal set of alignments that cover a query using a biologically relevant breakpoint penalty. YAHA can also report multiple mappings per defined segment of the query. We show that YAHA detects more breakpoints in less time than BWA-SW across all SV classes, and especially excels at complex SVs comprising multiple breakpoints.</p>
<p><strong>Availability:</strong> YAHA is currently supported on 64-bit Linux systems. Binaries and sample data are freely available for download from <a href="http://faculty.virginia.edu/irahall/YAHA" target="pmc_ext">http://faculty.virginia.edu/irahall/YAHA</a>.</p>
<p><strong>Contact:</strong></p>
<p>http://genome.wustl.edu/people/groups/detail/hall-lab/</p><p>Address of the bookmark: <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463118/" rel="nofollow">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463118/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/30657/studentship</guid>
  <pubDate>Tue, 24 Jan 2017 04:26:14 -0600</pubDate>
  <link></link>
  <title><![CDATA[Studentship]]></title>
  <description><![CDATA[
<p>Advt. No. ACBR/BTBI/BIF/Manpower/ADV/16-17<br />Research Associate/ Studentship/ Traineeship Jobs opportunity in  University of Delhi - Dr. B.R. Ambedkar Center for Biomedical Research (ACBR) on temporary basis<br />Studentship<br />No. of Post : 01<br />Qualifications : Applicants who are pursuing Post Graduate Degree course/ Diploma in Bioinformatics/ Biomedical Sciences/ Biotechnology/Life Sciences/Chemistry/ Biochemistry with a programme in Bioinformatics to carry out the project.<br />Remuneration : Rs. 8,000/-<br />Traineeship<br />No. of Post : 01<br />Qualifications : Applicants who have completed their Post Graduate degree in Bioinformatics /Biomedical Sciences/Biotechnology/Life Sciences/Chemistry/Biochemistry or any other branch of Life Sciences with knowledge in Bioinformatics<br />Remuneration : Rs. 8,000/-<br />Research Associate<br />No. of Post : 01<br />Qualifications : Ph.D. in Bio-Medical Sciences/Bioinformatics/ Biotechnology/Life Sciences/ Chemistry/ Bio-Chemistry and related areas<br />Remuneration : Rs. 36,000/-</p>

<p>Applicant are required to bring applications on plain paper, stating the name, address, date of birth. educational qualifications and experiences and Institute, along with attested photocopies of mark sheets and certificates etc. at the time of Interview. Applications should also be sent by Entail to Dr. Madhu Chopra, Coordinator, BIF Facility. Email: acbrdu.blisnet@nic.in;  mchopradu@gmail.com.<br />Interview Date : 13.02.2017<br />Time : 10:00 am-12:00 noon<br />Venue : ACBR</p>
]]></description>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/30696/many-core-engine-mce-for-perl-example</guid>
	<pubDate>Tue, 31 Jan 2017 05:37:50 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/30696/many-core-engine-mce-for-perl-example</link>
	<title><![CDATA[Many-Core Engine (MCE) for Perl example]]></title>
	<description><![CDATA[<p><span>MCE spawns a pool of workers and therefore does not fork a new process per each element of data. Instead, MCE follows a bank queuing model. Imagine the line being the data and bank-tellers the parallel workers. MCE enhances that model by adding the ability to chunk the next n elements from the input stream to the next available worker.</span></p>
<p>CORE MODULES</p>
<p>Three modules make up the core engine for MCE.</p>
<dl><dt id="MCE::Core"><a href="https://metacpan.org/pod/MCE#MCE::Core"><span></span></a><a></a><a href="https://metacpan.org/pod/distribution/MCE/lib/MCE/Core.pod">MCE::Core</a></dt><dd>
<p>Provides the Core API for Many-Core Engine. The various MCE options are described here.</p>
</dd><dt id="MCE::Signal"><a href="https://metacpan.org/pod/MCE#MCE::Signal"><span></span></a><a></a><a href="https://metacpan.org/pod/MCE::Signal">MCE::Signal</a></dt><dd>
<p>Temporary directory creation, cleanup, and signal handling.</p>
</dd><dt id="MCE::Util"><a href="https://metacpan.org/pod/MCE#MCE::Util"><span></span></a><a></a><a href="https://metacpan.org/pod/MCE::Util">MCE::Util</a></dt><dd>
<p>Utility functions for Many-Core Engine.</p>
</dd></dl>
<p><a href="https://metacpan.org/pod/MCE#MCE-EXTRAS"><span></span></a><a></a>MCE EXTRAS</p>
<p>There are 4 add-on modules for use with MCE.</p>
<dl><dt id="MCE::Candy"><a href="https://metacpan.org/pod/MCE#MCE::Candy"><span></span></a><a></a><a href="https://metacpan.org/pod/MCE::Candy">MCE::Candy</a></dt><dd>
<p>Provides a collection of sugar methods and output iterators for preserving output order.</p>
</dd><dt id="MCE::Mutex"><a href="https://metacpan.org/pod/MCE#MCE::Mutex"><span></span></a><a></a><a href="https://metacpan.org/pod/MCE::Mutex">MCE::Mutex</a></dt><dd>
<p>Provides a simple semaphore implementation supporting threads and processes.</p>
</dd><dt id="MCE::Queue"><a href="https://metacpan.org/pod/MCE#MCE::Queue"><span></span></a><a></a><a href="https://metacpan.org/pod/MCE::Queue">MCE::Queue</a></dt><dd>
<p>Provides a hybrid queuing implementation for MCE supporting normal queues and priority queues from a single module. MCE::Queue exchanges data via the core engine to enable queuing to work for both children (spawned from fork) and threads.</p>
</dd><dt id="MCE::Relay"><a href="https://metacpan.org/pod/MCE#MCE::Relay"><span></span></a><a></a><a href="https://metacpan.org/pod/MCE::Relay">MCE::Relay</a></dt><dd>
<p>Enables workers to receive and pass on information orderly with zero involvement by the manager process while running.</p>
</dd></dl>
<p><a href="https://metacpan.org/pod/MCE#MCE-MODELS"><span></span></a><a></a>MCE MODELS</p>
<p>The models take Many-Core Engine to a new level for ease of use. Two options (chunk_size and max_workers) are configured automatically as well as spawning and shutdown.</p>
<dl><dt id="MCE::Loop"><a href="https://metacpan.org/pod/MCE#MCE::Loop"><span></span></a><a></a><a href="https://metacpan.org/pod/MCE::Loop">MCE::Loop</a></dt><dd>
<p>Provides a parallel loop utilizing MCE for building creative loops.</p>
</dd><dt id="MCE::Flow"><a href="https://metacpan.org/pod/MCE#MCE::Flow"><span></span></a><a></a><a href="https://metacpan.org/pod/MCE::Flow">MCE::Flow</a></dt><dd>
<p>A parallel flow model for building creative applications. This makes use of user_tasks in MCE. The author has full control when utilizing this model. MCE::Flow is similar to MCE::Loop, but allows for multiple code blocks to run in parallel with a slight change to syntax.</p>
</dd><dt id="MCE::Grep"><a href="https://metacpan.org/pod/MCE#MCE::Grep"><span></span></a><a></a><a href="https://metacpan.org/pod/MCE::Grep">MCE::Grep</a></dt><dd>
<p>Provides a parallel grep implementation similar to the native grep function.</p>
</dd><dt id="MCE::Map"><a href="https://metacpan.org/pod/MCE#MCE::Map"><span></span></a><a></a><a href="https://metacpan.org/pod/MCE::Map">MCE::Map</a></dt><dd>
<p>Provides a parallel map model similar to the native map function.</p>
</dd><dt id="MCE::Step"><a href="https://metacpan.org/pod/MCE#MCE::Step"><span></span></a><a></a><a href="https://metacpan.org/pod/MCE::Step">MCE::Step</a></dt><dd>
<p>Provides a parallel step implementation utilizing MCE::Queue between user tasks. MCE::Step is a spin off from MCE::Flow with a touch of MCE::Stream. This model, introduced in 1.506, allows one to pass data from one sub-task into the next transparently.</p>
</dd><dt id="MCE::Stream"><a href="https://metacpan.org/pod/MCE#MCE::Stream"><span></span></a><a></a><a href="https://metacpan.org/pod/MCE::Stream">MCE::Stream</a></dt><dd>
<p>Provides an efficient parallel implementation for chaining multiple maps and greps together through user_tasks and MCE::Queue. Like with MCE::Flow, MCE::Stream can run multiple code blocks in parallel with a slight change to syntax from MCE::Map and MCE::Grep.</p>
</dd></dl>
<p><a href="https://metacpan.org/pod/MCE#MISCELLANEOUS"><span></span></a>MISCELLANEOUS</p>
<p>Miscellaneous additions included with the distribution.</p>
<dl><dt id="MCE::Examples"><a href="https://metacpan.org/pod/MCE#MCE::Examples"><span></span></a><a></a><a href="https://metacpan.org/pod/distribution/MCE/lib/MCE/Examples.pod">MCE::Examples</a></dt><dd>
<p>Describes various demonstrations for MCE including a Monte Carlo simulation.</p>
</dd><dt id="MCE::Subs"><a href="https://metacpan.org/pod/MCE#MCE::Subs"><span></span></a><a></a><a href="https://metacpan.org/pod/MCE::Subs">MCE::Subs</a></dt><dd>
<p>Exports functions mapped directly to MCE methods; e.g. mce_wid. The module allows 3 options; :manager, :worker, and :getter.</p>
</dd></dl>
<p><a href="https://metacpan.org/pod/MCE#REQUIREMENTS"><span></span></a>REQUIREMENTS</p>
<p>Perl 5.8.0 or later. PDL::IO::Storable is required in scripts running PDL.</p>
<p><a href="https://metacpan.org/pod/MCE#SOURCE-AND-FURTHER-READING"><span></span></a><a></a>SOURCE AND FURTHER READING</p>
<p>The source, cookbook, and examples are hosted at GitHub.</p>
<ul>
<li>
<p><a href="https://github.com/marioroy/mce-perl">https://github.com/marioroy/mce-perl</a></p>
</li>
<li>
<p><a href="https://github.com/marioroy/mce-cookbook">https://github.com/marioroy/mce-cookbook</a></p>
</li>
<li>
<p><a href="https://github.com/marioroy/mce-examples">https://github.com/marioroy/mce-examples</a></p>
</li>
</ul>
<p><a href="https://metacpan.org/pod/MCE#SEE-ALSO"><span></span></a><a></a>SEE ALSO</p>
<p><code>MCE::Shared</code>&nbsp;provides data sharing capabilities for&nbsp;<code>MCE</code>. It includes&nbsp;<code>MCE::Hobo</code>&nbsp;for running code asynchronously.</p>
<ul>
<li>
<p><a href="https://metacpan.org/pod/MCE::Shared">MCE::Shared</a></p>
</li>
<li>
<p><a href="https://metacpan.org/pod/MCE::Hobo">MCE::Hobo</a></p>
</li>
</ul><p>Address of the bookmark: <a href="https://github.com/marioroy/mce-examples" rel="nofollow">https://github.com/marioroy/mce-examples</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/30747/11th-international-joint-conference-on-biomedical-engineering-systems-and-technologies</guid>
  <pubDate>Wed, 01 Feb 2017 17:39:27 -0600</pubDate>
  <link></link>
  <title><![CDATA[11th International Joint Conference on Biomedical Engineering Systems and Technologies]]></title>
  <description><![CDATA[
<p>BIOSTEC, the 11th International Joint Conference on Biomedical Engineering Systems and Technologies.<br /> Registration to BIOINFORMATICS allows free access to all other BIOSTEC conferences. </p>

<p>Upcoming Deadlines<br />Regular Paper Submission: July 31, 2017 <br />Regular Paper Authors Notification: October 16, 2017 <br />Regular Paper Camera Ready and Registration: October 30, 2017 </p>

<p>The purpose of the International Conference on Bioinformatics Models, Methods and Algorithms is to bring together researchers and practitioners interested in the application of computational systems, algorithmic concepts and information technologies to address challenging problems in Biomedical research with a particular focus on the emerging problems in Bioinformatics and computational biology. There is a tremendous need to explore how mathematical, statistical and computational models can be used to better understand biological processes and systems, while developing new methodologies and tools to analysis the massive currently-available biological data. Areas of interest to this community include systems biology, sequence analysis, biostatistics, image analysis, network and graph models, scientific data management and data mining, machine learning, pattern recognition, computational evolutionary biology, computational genomics and proteomics, and related areas.</p>
]]></description>
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<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/30831/fsa-fast-statistical-alignment</guid>
	<pubDate>Mon, 06 Feb 2017 04:26:01 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/30831/fsa-fast-statistical-alignment</link>
	<title><![CDATA[FSA: Fast Statistical Alignment]]></title>
	<description><![CDATA[<p><span>FSA is a probabilistic multiple sequence alignment algorithm which uses a "distance-based" approach to aligning homologous protein, RNA or DNA sequences. Much as distance-based phylogenetic reconstruction methods like Neighbor-Joining build a phylogeny using only pairwise divergence estimates, FSA builds a multiple alignment using only pairwise estimations of homology. This is made possible by the sequence annealing technique for constructing a multiple alignment from pairwise comparisons, developed by Ariel Schwartz in&nbsp;</span><a href="http://www.eecs.berkeley.edu/Pubs/TechRpts/2007/EECS-2007-39.html">"Posterior Decoding Methods for Optimization and Control of Multiple Alignments</a><span>."</span></p>
<p>FSA brings the high accuracies previously available only for small-scale analyses of proteins or RNAs to large-scale problems such as aligning thousands of sequences or megabase-long sequences. FSA introduces several novel methods for constructing better alignments:</p>
<ul>
<li>FSA uses machine-learning techniques to estimate gap and substitution parameters on the fly for each set of input sequences. This "query-specific learning" alignment method makes FSA very robust: it can produce superior alignments of sets of homologous sequences which are subject to very different evolutionary constraints.</li>
<li>FSA is capable of aligning hundreds or even thousands of sequences using a randomized inference algorithm to reduce the computational cost of multiple alignment. This randomized inference can be over ten times faster than a direct approach with little loss of accuracy.</li>
<li>FSA can quickly align very long sequences using the "anchor annealing" technique for resolving anchors and projecting them with transitive anchoring. It then stitches together the alignment between the anchors using the methods described above.</li>
<li>The included GUI, MAD (Multiple Alignment Display), can display the intermediate alignments produced by FSA, where each character is colored according to the probability that it is correctly aligned (see the picture and&nbsp;<a href="http://fsa.sourceforge.net/images/Suchard_SIV.fsa.mov">movie</a>&nbsp;at the top of the page).</li>
</ul>
<p><span>You can see more information on the&nbsp;</span><a href="http://fsa.sourceforge.net/FAQ.html">FAQ</a><span>.&nbsp;</span></p>
<p>&nbsp;</p><p>Address of the bookmark: <a href="http://fsa.sourceforge.net/" rel="nofollow">http://fsa.sourceforge.net/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>

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