It was first developed to transfer annotations between different genome assembly versions. However, it can also transfer annotations between strains and even different species, like Plasmodium chabaudi onto P. berghei, between different Leishmania species or Salmonella enterica onto other Salmonella serotypes. RATT is able to transfer any entries present on a reference sequence, such as the systematic id or an annotator's notes; such information would be lost in a de novo annotation.

More at http://ratt.sourceforge.net/

Address of the bookmark: http://ratt.sourceforge.net/

• Automatically improve draft assemblies
• Find variation among strains, including large event detection

Pilon requires as input a FASTA file of the genome along with one or more BAM files of reads aligned to the input FASTA file. Pilon uses read alignment analysis to identify inconsistencies between the input genome and the evidence in the reads. It then attempts to make improvements to the input genome, including:

• Single base differences
• Small indels
• Larger indel or block substitution events
• Gap filling
• Identification of local misassemblies, including optional opening of new gaps

More at https://github.com/broadinstitute/pilon/wiki

Address of the bookmark: https://github.com/broadinstitute/pilon/wiki

Lift over is the process of transferring annotations from one genome assembly to another. Usually lift over is done because there is a new, improved genome assembly for the species and good quality annotations (maybe manually curated or experimentally verified) are available on the old assembly.

The idea is simple: align the new assembly with the old one (e.g., with BLAT), process the alignment data to define how a coordinate or coordinate range on the old assembly should be transformed to the new assembly (e.g., as a chain file), transform the coordinates (e.g., with liftOver).

https://github.com/wurmlab/flo

Address of the bookmark: https://github.com/wurmlab/flo

Eligibility : ME/M.Tech, Any Graduate, MSc

Location : Shillong

Last Date : 23 Feb 2016

Hiring Process : Face to Face Interview
North Eastern Hill University

Project Assistant/ JRF Jobs recruitment in North Eastern Hill University on temporary basis

Project Title : "Next Generation Sequencing (NGS)-based de novo assembly of expressed transcripts and genome information of Orchids in North-East India"

Project Assistant

No. of Post : 01

Qualifications : Graduation

Desirable : Experience of working in a Life Science/Plant Biotechnology lab. and familiarity with computers and field work viz. collection of samples.

JRF

No. of Post : 01

Qualifications : M.Tech/M.Sc in Life Sciences/Botany/Biotechnology/ Bioinformatics;

Desirable : Aptitude for Bioinformatics and Computer Programming/ Next generation sequencing data analysis
How to apply

The applications through email bicnehu@gmail.com or post must reach the Dr. Devendra Kumar Biswal, Co-Principal Investigator (Co-PI) within 15 days from the date of publication of this advertisement.

More at http://www.nehu.ac.in/Advertisements/projectVacancy.php

This book is suitable for classroom use as a general introduction to programming concepts.

More at http://tldp.org/LDP/abs/html/

Address of the bookmark: http://tldp.org/LDP/abs/html/

Eligibility : MSc, M Phil / Phd, BE/B.Tech

Location : Delhi

Last Date : 08 Mar 2016

Hiring Process : Walk - In
Regional Medical Research Centre -

Notification Order No.1-51/Proj/RMRC/PB/

Scientist – II (Post Code: BIC-II) job position in Regional Medical Research Centre (ICMR)

Essential Qualification: 1 st class Master’s degree in Bioinformatics / Computational Biology. B.E / B.Tech (Bioinformatics / Computer Science / Biotechnology) OR 2nd Class M.Sc. with Ph.D. in Bioinformatics / Computational Biology / Life Science.

Desirable Qualification: Post-doctoral research experience in Bioinformatics / Computational Biology / Computer Science / Life Science at a recognized institution. Experience in handling and analyzing sequencing data. Experience in scripting languages (PERL/PYTHON) etc./ Statistical software. Experience in developing research projects.

Number of Post: 1 UR

Place of Posting: RMRC, Port Blair

Age Limit: 40 years

Pay Scale : Rs.45,954
How to apply

Interested candidates are invited to submit applications along with copies of all the certificates of educational qualifications, date of birth, working experience etc . on the affixing a passport size photograph by Application Format to attend a walk-in interview on 8th March 2016 at 10:30 AM.

More at http://www.icmr.nic.in/icmrnews/port%20blair%20Bioinf%2003-2016.pdf

More at https://github.com/mills-lab/svelter/

Address of the bookmark: https://github.com/mills-lab/svelter/

JRF jobs in International Centre for Genetic Engineering and Biotechnology

Area of research: Computational analysis of protein-protein interactions and metabolic reconstruction of pathways

Qualification : Suitable candidate must have completed Masters in Computer Science/Physics/Mathematics/Bioinformatics or PG diploma in Bioinformatics with very sound programming skills shown in the form of completed project or paper. Programming Skill required: Java/perl/python or any other scripting language and working knowledge of MySQL. Candidate should have some familiarity with R statistical package.

The salary will be as per the guidelines of DBT/DST, based on qualification and experience.

How to apply

Interested candidates may send application along with CV via email to hemant@icgeb.res.in (Dr. Hemant Ritturaj Kushwaha) on or before 08/03/2016. Candidates applying through Email must mention “Application for JRF” in their subject line.

More at http://www.icgeb.org/vacancies.html

Note that the information on this page is targeted at end-users. For developers, the source code, building instructions and implementation/development resources are available on GitHub.

The Picard toolkit is open-source under the MIT license and free for all uses.

Enjoy!

Address of the bookmark: http://broadinstitute.github.io/picard/

Essential qualification : Ph.D. in Bioinformatics/Biotechnology/Genetics/Computational Biology.Understanding of genomics data and advanced knowledge of Java, and C/C++ as the programming languages and the scripting language like perl and/or Python, SQL is preferred. Experience in High Performance Computing, data architecture, database development is desirable

Fellowship: Rs 35,000 /-

How to apply

Candidates are requested to send their CV, and a brief summary of research experience by e-mail careers.genetics@ktr.srmuniv.ac.in on or before 30/03/2016.

More at http://www.srmuniv.ac.in/jobs-applications-for-position-of-post-doctoral-fellow