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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/1886?offset=250</link>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/29998/csir-nehru-science-postdoctoral-research-fellowship</guid>
  <pubDate>Tue, 29 Nov 2016 12:34:59 -0600</pubDate>
  <link></link>
  <title><![CDATA[CSIR Nehru Science Postdoctoral Research Fellowship]]></title>
  <description><![CDATA[
<p>CSIR Nehru Science Postdoctoral Research Fellowship</p>

<p>About Fellowship: <br />CSIR Nehru Science Postdoctoral Research Fellowship Scheme is an Research Fellowship awarded/given by HRD Ministry, Govt. of India every year to more than 100 fellows.</p>

<p>It was started to identify promising and young researchers with novel ideas and provide them research opportunities in the areas of basic science, engineering, medicine &amp; agriculture.</p>

<p>The fellowship aims at facilitating their transition from mentored to independent research career.</p>

<p>In addition, check these ICTS Research Fellowships:<br />1.) Max-Planck Partner Group Fellowships 2017-18<br />2.) ICTS-Simons Postdoctoral Fellowships 2017<br />3.) ICTS Post Doctoral Fellowships 2017<br />4.) Airbus Prize Postdoctoral Fellowship 2017-18</p>

<p>Eligibility: To be eligible for this fellowship, you:<br />1.) PhD degree (within 3 years of award of PhD degree), OR<br />2.) Those who have submitted PhD theses.<br />3.) Applicants should have research publications in good impact factor SCI journals.<br />4.) Indian nationals, Persons of Indian Origin (PIO) &amp; Overseas Citizen of India (OCI), a can also apply.<br />5.) Maximum Age Limit: 32 years.</p>

<p>Duration: <br />– 2 Years.<br />– extendable for a maximum of 1 more year based on performance.</p>

<p>Remuneration: <br />– Rs. 50,000/- per month plus House Rent Allowance (HRA)<br />– A contingency grant of Rs. 3.0 lakh per annum.<br />– 25% of the contingency grant can be used for domestic and international travel.</p>

<p>Mode of Selection: You can apply throughout the year, but selection will be made twice a year, in June and December.</p>

<p>How to Apply: <br />– Read the instructions, given at Annexure-I in this PDF file.<br />– And, application form is given as, Annexure-II.<br />– Fill the form &amp; send it to the given address in the PDF file.</p>

<p>Deadline: Rolling Deadline (Applications accepted throughout the year)</p>

<p>Also See: Research Internship/ Fellowship in India:<br />1.) IIT Bombay Research Internship Awards Programme 2016-17<br />2.) IIT Delhi Internship Program 2016-17<br />3.) DAAD WISE – International Internship in Germany<br />4.) Summer Research Fellowship Programme| JNCASR Bangalore<br />5.) Indian Academy of Sciences Summer Internships 2017<br />6.) Winter Internship – IIT Bombay NPDE-TCA<br />7.) Viterbi – India Program 2017 | Research Internship in US<br />8.) Internship – Centre for Stem Cell Research, Vellore</p>

<p>Accommodation &amp; other benefits: <br />– Accommodation may be provided by CSIR, if available.<br />– Medical benefits as per CSIR norms.</p>

<p>For more details: <br />– Check this PDF Notification of Fellowship.<br />– List of CSIR Labs &amp; their work/activities can be seen at www.csir.res.in.</p>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/30928/jrf-bioinformatics-job-vacancies-in-tezpur-university</guid>
  <pubDate>Tue, 14 Feb 2017 16:40:26 -0600</pubDate>
  <link></link>
  <title><![CDATA[JRF Bioinformatics job vacancies in Tezpur University]]></title>
  <description><![CDATA[
<p>Memo No. DoRD/CSE/SSS/20-295/112-A Date: 01/02/2017</p>

<p>Project Title : Integrating genome scale metabolic analysis of model plant pathogen Ralstonia solanacearum with RNAseq and fluxomics</p>

<p>Essential qualification : M.Tech. in CSE/IT (With specialization in Computational Biology/Bioinformatics) or M.Sc. in Bioinformatics/Biosciences/Molecular Biology Biotechnology preferably with NET/GATE/BET. Candidates should have minimum 55 % mark both in 10th and 10+2 Science examinations and mathematics at 10+2 Science. Desirable: Preference will be given to the candidates having experience in computational analysis of genome sequences or similar projects.</p>

<p>No. of Post : 01</p>

<p>Remuneration : Rs. 25,000/- for the 1st two years and Rs. 28,000/- for the 3rd year for SRF and applicable to the candidate having post graduate degree in Basic Science with NET/GATE/BET qualification or post graduate degree in professional course. Rs. 12,000/- for the 1st two years and Rs. 14,000/- for the 3 rd year for SRF, </p>

<p>Age : 28 years</p>

<p>Duration : Three (03) years or till completion of the project or until further order, whichever is earlier.</p>

<p>Hiring Process : Walk - In<br />Job Role: Research/JRF/SRF</p>

<p>Walk-in-interview will be held on 17th February, 2017, 11.15 a.m. at the office of the Head, Department of Computer Science and Engineering, Tezpur University.</p>

<p>Interested candidates may appear before the interview board with original documents from 10th standard onwards and photocopies of mark sheets, certificates, testimonials, caste certificate (if applicable), experience certificate certificates of NET/GATE/BET or similar examination qualifications, any other testimonials and a copy of recent curriculum vitae (CV) on the day of interview.</p>

<p>More at http://www.tezu.ernet.in/ProjectWalkin/Advt-DoRD-CSE-SSS-20-295-112-A.pdf</p>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/31258/bioinformatics-walk-in-interview-at-tezpur-university</guid>
  <pubDate>Thu, 02 Mar 2017 04:24:46 -0600</pubDate>
  <link></link>
  <title><![CDATA[Bioinformatics walk-in-interview at Tezpur University]]></title>
  <description><![CDATA[
<p>A walk-in-interview will be held on 09 March, 2017, 11.15 a.m. at the office of the Head, Department of Computer Science and Engineering, Tezpur University for one (01) temporary position of Junior Research Fellow (JRF) in the DBT, Govt. of India sponsored project entitled “Integrating genome scale metabolic analysis of model plant pathogen Ralstonia solanacearum with RNAseq and fluxomics” under Dr. Siddhartha Sankar Satapathy (ssankar@tezu.ernet.in), Associate Professor, Department of Computer Science and Engineering, Tezpur University.<br /> <br />Interested candidates may appear before the interview board with original documents from 10th standard onwards and photocopies of mark sheets, certificates, testimonials, caste certificate (if applicable), experience certificate certificates of NET/GATE/BET or similar examination qualifications, any other testimonials and a copy of recent curriculum vitae (CV) on the day of interview.<br /> <br />Essential qualification: M.Tech. in CSE/IT (With specialization in Computational Biology/Bioinformatics) or M.Sc. in Bioinformatics/Biosciences/Molecular Biology Biotechnology preferably with NET/GATE/BET.<br /> <br />Candidates should have minimum 55 % mark both in 10th and 10+2 Science examinations and mathematics at 10+2 Science.<br /> <br />Desirable: Preference will be given to the candidates having experience in computational analysis of genome sequences or similar projects.<br /> <br />Remuneration: Rs. 25,000/- (Rupees twenty five thousand) only + HRA as admissible per month for the 1st two years and Rs. 28,000/- (Rupees twenty eight thousand) only + HRA as admissible per month for the 3rd year for SRF and applicable to the candidate having post graduate degree in Basic Science with NET/GATE/BET qualification or post graduate degree in professional course. Rs. 12,000/- (Rupees twelve thousand) only + HRA as admissible per month for the 1st two years and Rs. 14,000/- (Rupees fourteen thousand) only + HRA as admissible per month for the 3 rd year for SRF, for the candidate without NET/GATE/BET qualification. HRA will not be provided if campus accommodation is availed.<br /> <br />Age: Candidate shall not be more than 28 years of age on the date of interview. Upper age limit may be relaxed up to 5 years in the case of candidate belonging to SC/ST/ OBC/Women/Differently abled.<br /> <br />Duration: Three (03) years or till completion of the project or until further order, whichever is earlier.<br /> <br />N.B. No TA/DA will be paid to the candidates for attending the interview. For further details please contact: Dr. S. S. Satapathy Associate Professor Department of Computer Science and Engineering Tezpur University, Napaam-784028 Email: ssankar@tezu.ernet.in Contact no.: +91-9435979648<br /> <br />More Info:  www.tezu.ernet.in/ProjectWalkin/Advt-DoRD-CSE-SSS-20-295-188-A.pdf</p>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/31520/research-associate-openings-at-iasri-india</guid>
  <pubDate>Fri, 10 Mar 2017 03:53:03 -0600</pubDate>
  <link></link>
  <title><![CDATA[Research Associate openings at IASRI, India]]></title>
  <description><![CDATA[
<p>Research Associate (RA) Two (2) </p>

<p>Ph.D. in Bioinformatics/ Agricultural Statistics/ Statistics/ Computer Science/ Computer Application or equivalent or Master’s in Bioinformatics/ Agricultural Statistics/ Statistics/ Computer Science/ Computer Application or equivalent with 4 years or 5 years of Bachelor’s degree having 1st Division or 60% marks or equivalent overall grade point average, with at least two years of research experience as evidenced from fellowship/ associateship/ training/ other engagements. </p>

<p>Knowledge in System Biology/ Statistical and computational Genomics/ Bioinformatics <br />Knowledge in computer programming, LINUX OS. <br />Expertise in use of R/other Bioinformatics software </p>

<p>More at http://iasri.res.in/employment/2017/cabin_advertisement_RA_SRF_YP_Mar2017.pdf</p>

<p>Phenomics of Moisture Deficit Stress Tolerance and Nitrogen Use December 31, 2019 </p>

<p>Research Associate (RA) Two (2) </p>

<p>Ph.D. in Bioinformatics/ Agricultural Statistics/ Statistics/ Computer Science/ Computer Application or equivalent or System Administrator/ Computer expert for database development, development of phenome data bank and virtual phenomics facility, data archiving and Efficiency in Rice and Wheat-Phase II (Funded by National Agricultural Science Fund, ICAR) Master’s in Bioinformatics/ Agricultural Statistics/ Statistics/ Computer Science/ Computer Application or equivalent with 4 years or 5 years of Bachelor’s degree having 1st Division or 60% marks or equivalent overall grade point average, with at least two years of research experience as evidenced from fellowship/ associateship/ training/ other engagements. maintenance; Development of image analysis algorithms, APIs and IAPs. </p>

<p>Knowledge in System Biology/ Statistical and computational Genomics/ Bioinformatics <br />Knowledge of programming in LINUX/R/Perl/JAVA/PHP/JSP and use of various software &amp; tools. <br />December 31, 2019 </p>

<p>Ph.D. in Bioinformatics/ Agricultural Statistics/ Statistics/ Computer Science / Computer Application or equivalent or Master’s in Bioinformatics/ Agricultural Statistics/ Statistics/ Computer Science/ Computer Application or equivalent with 4 years or 5 years of Bachelor’s degree having 1st Division or 60% marks or equivalent overall grade point average, with at least two years of research experience as evidenced from fellowship/ associateship/ training/ other engagements. </p>

<p>Knowledge of Statistical and Computational Genomics/ Bioinformatics. <br />Knowledge of programming in LINUX/R/Perl/JAVA/PHP/JSP and use of various software &amp; tools. <br />March 31, 2020</p>
]]></description>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/1149/system-biologist-at-millennium-software-productions-india-private-limited</guid>
  <pubDate>Fri, 19 Jul 2013 09:43:53 -0500</pubDate>
  <link></link>
  <title><![CDATA[System Biologist at Millennium Software productions India Private Limited]]></title>
  <description><![CDATA[
<p>Millennium Software productions India Private Limited</p>

<p>www.cytosolve.com</p>

<p>Post - System Biologist</p>

<p>Job Description: Role of system biology is to design quantitative models of bimolecular networks and to study interactions between the components of biological systems, and how these interactions give rise to the function and behavior of that system (Enzyme, metabolites and pathway).</p>

<p>Qualification : B.Tech or M.Sc in Bioinformatics</p>

<p>Required Skills:</p>

<p>1) Basic knowledge of cell signaling pathways, chemical/enzyme kinetics, and differential equation based modeling approach.<br />2) Previous laboratory experience could be an advantage<br />3) Good Communication skills.</p>

<p>santhiya.ram@mproductions.com and 044-42946555.</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/33741/diya-a-bacterial-annotation-pipeline-for-any-genomics-lab</guid>
	<pubDate>Fri, 30 Jun 2017 08:48:26 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/33741/diya-a-bacterial-annotation-pipeline-for-any-genomics-lab</link>
	<title><![CDATA[DIYA: a bacterial annotation pipeline for any genomics lab]]></title>
	<description><![CDATA[<p><span>DIY Genomics is an open source bioinformatics consortium intended to bring a collection of tools and libraries into the hands of small scale genomics labs for the process of sequence assembly and annotation. Projects include DIYA, MGAP, CRISPR, and DIYGV</span></p>
<p><span>http://gmod.org/wiki/Diya</span></p><p>Address of the bookmark: <a href="https://sourceforge.net/projects/diyg/" rel="nofollow">https://sourceforge.net/projects/diyg/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/1720/postdoctoral-associate-bioinformatics-at-duke-university-medical-center</guid>
  <pubDate>Sat, 10 Aug 2013 18:38:38 -0500</pubDate>
  <link></link>
  <title><![CDATA[Postdoctoral Associate - Bioinformatics  at Duke University Medical Center]]></title>
  <description><![CDATA[
<p>The Department of Biostatistics and Bioinformatics at Duke University Medical Center is seeking a Postdoctoral Associate for a one year appointment to work on several high-dimensional research projects. The specific goals of the project are to identify genes or molecular markers that are predictive of clinical outcomes in renal and prostate cancer.</p>

<p>Candidates must have: a PhD degree in statistics, biostatistics or bioinformatics, extensive experience in analyzing high-dimensional data (microarray, SNP, CNVs) and of validation approaches. In addition, experience in penalized regression methods, data base manipulation; and strong programming skills in order to conduct Monte Carlo studies and applications (R). Candidate must have excellent communication skills (verbal, written and presentation), a strong proficiency in Linux system.</p>

<p>This position is available immediately and will be filled as soon as possible. Appointment could be extended beyond the first year based on additional funding.</p>

<p>For more information about the Department of Biostatistics and Bioinformatics, please visit our website: http://www.biostat.duke.edu.</p>

<p>For more info: http://biostat.duke.edu/sites/biostat.duke.edu/files/Halabi%20-%20Postdoc%20Job%20Posting%202013%20updated.pdf</p>

<p>Duke University is an Equal Opportunity/Affirmative Action Employer.</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/2334/binc-bioinformatics-national-certification-website-address</guid>
	<pubDate>Wed, 14 Aug 2013 09:40:22 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/2334/binc-bioinformatics-national-certification-website-address</link>
	<title><![CDATA[BINC (BioInformatics National Certification) Website address]]></title>
	<description><![CDATA[<p><span>BINC (BioInformatics National Certification) is an initiative of Department of Biotechnology(DBT), Government Of India in coordination with Bioinformatics Center, University of Pune. The objective of the examination is to recognize trained manpower in the area of Bioinformatics. Currently, various Indian universities, Government and private institutions are involved in imparting courses in Bioinformatics in India.</span></p>
<p>Foreign nationals intending to have certification are eligible to appear for BINC examination.<br>Minimum qualification includes a degree from a recognized university/institute in the areas listed in FAQ.<br>Formal training in the area of Bioinformatics is not a prerequisite.<br>Note that the foreign students will only be certified by DBT and are not eligible for the cash award as well as junior research fellowship.</p><p>Address of the bookmark: <a href="http://binc.scisjnu.ernet.in/" rel="nofollow">http://binc.scisjnu.ernet.in/</a></p>]]></description>
	<dc:creator>Kamalakshi Mukherjee</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/36281/binc-bioinformatics-national-certification-examination-2018</guid>
	<pubDate>Mon, 23 Apr 2018 03:34:53 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/36281/binc-bioinformatics-national-certification-examination-2018</link>
	<title><![CDATA[BINC (Bioinformatics National Certification) Examination 2018]]></title>
	<description><![CDATA[<p>Bioinformatics National Certification (BINC) was instituted by Department of Biotechnology, Government of India in 2005 at Savitribai Phule Pune University, formerly University of Pune, Pune to certify bioinformatics professionals and recognizing candidate's theoretical and practical ability and fostering interdisciplinary research. Later on, it was transferred to Jawaharlal Nehru University, New Delhi and then to Pondicherry University, Puducherry. Pondicherry University conducted the BINC examination in 2015, 2016 and 2017.</p><div><p>Biotech Consortium India Limited (BCIL), New Delhi is conducting the BINC 2018 examination on behalf Department of Biotechnology, Government of India.</p></div><div><p>BINC is a certification programme for graduate and post-graduate students for recognizing their exceptional bioinformatics knowledge and skills and to improve their employment opportunities. There is a growing need for trained manpower in the area of Bioinformatics. Currently, various universities and institutions, both government and private, impart Bioinformatics education in India. The qualifying candidates will be awarded a lifetime certificate. This certification would facilitate industries and potential employers in recruitment of Bioinformatics professionals having exceptionally good bioinformatics skills.</p></div><div><p>The certification under Bioinformatics National Certification (BINC) scheme is given to the candidates after three tier selection process. The successful candidates are also eligible for availing Junior Research Fellowship (JRF) for pursuing Ph.D. in Bioinformatics at recognized Indian universities/institutes. The research fellowships of all BINC qualified Indian nationals are funded by DBT. BINC qualified candidates are called DBT certified Bioinformaticians while the individuals availing the fellowships are called as DBT-BINC Junior Research Fellows (DBT-BINC-JRF). Cash prize of 10,000/- each is awarded to the top 10 BINC qualifiers.</p></div><div><p><strong>Eligibility</strong></p></div><div><p>i) Bachelor's/Master's degree in Life Sciences, Physical Sciences, Chemical Sciences, Mathematical Sciences, Agriculture, Veterinary, Medicine, Pharmacy, Engineering and Technology.&nbsp;</p></div><div><p>ii) No formal training, diploma or certificate in bioinformatics is required.</p></div><div><p>iii) Candidates in final year of Bachelor's/ Master's degree are also eligible to apply.</p></div><div><p><strong><a href="http://bcil.nic.in/PatternofExamination.html" target="_blank">Pattern of Examination&nbsp;</a></strong></p></div><div><p><strong>Syllabus</strong>&nbsp;</p></div><div><p>The syllabus consists of six sections - Bioinformatics, Biology, Physical Science, Chemical Science, Mathematics &amp; Statistics, and Information Technology.</p></div><div><ul>
<li><a href="http://bcil.nic.in/files/BINC/BINC_SYLLABUS_for_Paper_I_2018.pdf" target="_blank">Syllabus for Paper-I (Objective)</a></li>
<li><a href="http://bcil.nic.in/files/BINC/BINC_SYLLABUS_for_Paper_II_2018.pdf" target="_blank">Syllabus for Paper-II (Short answers)</a></li>
<li><a href="http://bcil.nic.in/files/BINC/BINC_SYLLABUS_for_Paper_III_2018.pdf" target="_blank">Syllabus for Paper-III (Practical)</a></li>
</ul></div><div><p><strong>Note: Paper-III will be computer based practical and will include programming on Bioinformatics</strong></p></div><div><p><strong><a href="http://bcil.nic.in/files/BINC/Important_Dates.pdf" target="_blank">Important Dates</a></strong></p></div><div><p><strong><a href="http://bcil.nic.in/files/BINC/Examination_Centers.pdf" target="_blank">Examination Centers&nbsp;</a></strong></p></div><div><p><strong><a href="http://bcil.nic.in/files/BINC/BINC_Fellowship.pdf" target="_blank">BINC Fellowship&nbsp;</a></strong></p></div><div><p><strong><a href="http://bcil.nic.in/formanddownload.html" target="_blank">Forms &amp; Downloads&nbsp;</a></strong></p></div><div><p><strong><a href="http://bcil.nic.in/files/BINC/FAQs.pdf" target="_blank">FAQs&nbsp;</a></strong>&nbsp;</p></div><div><h3>Contact Us</h3></div><div><ul>
<li>Nisha Singh</li>
<li>Biotech Consortium India Limited</li>
<li>(CIN: U73100DL1990PLC041486)</li>
<li>5th Floor, Anuvrat Bhawan 210, Deen Dayal Upadhyaya Marg New Delhi - 110 002</li>
<li>Tel.: 011-2321 9064-67 Ext. 231, 236</li>
<li>Email - For general BINC queries:<a href="mailto:binc.dbt@biotech.co.in" target="_blank">binc.dbt@biotech.co.in</a></li>
<li>Helpline for Application submission related queries:<a href="mailto:binc.binchelpdesk@biotech.co.in" target="_blank">binchelpdesk@biotech.co.in</a></li>
<li>Website:&nbsp;<a href="http://bcil.nic.in/BINC.html" target="_blank">www.bcil.nic.in/BINC.html</a></li>
</ul></div>]]></description>
	<dc:creator>Jit</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/pages/view/7674/useful-publications-and-websites-for-deep-sequencing-data-analysis</guid>
	<pubDate>Sun, 29 Dec 2013 22:30:45 -0600</pubDate>
	<link>https://bioinformaticsonline.com/pages/view/7674/useful-publications-and-websites-for-deep-sequencing-data-analysis</link>
	<title><![CDATA[Useful Publications and Websites for Deep Sequencing Data Analysis]]></title>
	<description><![CDATA[<h3>Global overview papers</h3><p>Next generation quantitative genetics in plants. Jim&eacute;nez-G&oacute;mez, Frontiers in Plant Science 2:77, 2011 <span style="text-decoration: underline;"><a href="http://www.frontiersin.org/Plant_Physiology/10.3389/fpls.2011.00077/full">Full Text</a> </span><em>[equally relevant to animal and microbial systems]</em></p><p>Sense from sequence reads: methods for alignment and assembly. Flicek &amp; Birney, Nat Methods 6(11 Suppl):S6-S12, 2009. <a href="http://www.nature.com/nmeth/journal/v6/n11s/full/nmeth.1376.html"><span style="text-decoration: underline;">Full Text</span></a></p><h3>Library construction and experimental design</h3><p>Statistical design and analysis of RNA sequencing data. Auer &amp; Doerge, Genetics 185(2):405-16, 2010. <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881125"><span style="text-decoration: underline;">PubMedCentral</span></a></p><p>Biases in Illumina transcriptome sequencing caused by random hexamer priming. Hansen et al., Nucleic Acids Res. 38(12): e131, 2010. <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896536"><span style="text-decoration: underline;">PubMedCentral</span></a></p><p>Analyzing and minimizing PCR amplification bias in Illumina sequencing libraries. Aird et al, Genome Biology 12:R18, 2011 <a href="http://genomebiology.com/2011/12/2/R18"><span style="text-decoration: underline;">Full Text</span></a></p><p>Amplification-free Illumina sequencing-library preparation facilitates improved mapping and assembly of GC-biased genomes. Kozarewa et al, Nature Methods 6(4):291-5, 2009 <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664327/"><span style="text-decoration: underline;">PubMedCentral</span></a></p><p>Cost-effective, high-throughput DNA sequencing libraries for multiplexed target capture. Rohland &amp; Reich, Genome Research 22(5): 939&ndash;946. <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337438/"><span style="text-decoration: underline;">PubMedCentral</span></a></p><h3>Data formats, data management, and alignment software tools<span style="text-decoration: underline;"> </span></h3><p>The Sequence Alignment/Map format and SAMtools. Li et al, Bioinformatics 25(16):2078-9, 2009 <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2723002"><span style="text-decoration: underline;">PubMedCentral</span></a></p><p>SAM format specification <a href="http://samtools.sourceforge.net/SAM1.pdf"><span style="text-decoration: underline;">file</span></a></p><p>Efficient storage of high throughput sequencing data using reference-based compression. Fritz et al, Genome Res 21(5):734-40, 2011. <a href="http://genome.cshlp.org/content/21/5/734.long"><span style="text-decoration: underline;">Full Text</span></a></p><p>Compression of DNA sequence reads in FASTQ format. Deorowicz &amp; Grabowski, Bioinformatics 27(6):860-2, 2011. <a href="http://www.ncbi.nlm.nih.gov/pubmed/21252073"><span style="text-decoration: underline;">PubMed</span></a></p><p>Fast and accurate short read alignment with Burrows-Wheeler transform. Li &amp; Durbin, Bioinformatics 25(14):1754-60, 2009. <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705234"><span style="text-decoration: underline;">PubMedCentral</span></a></p><p>Improving SNP discovery by base alignment quality. Li H, Bioinformatics 27(8):1157-8, 2011. <a href="http://www.ncbi.nlm.nih.gov/pubmed/21320865"><span style="text-decoration: underline;">PubMed</span></a></p><p>BEDTools: a flexible suite of utilities for comparing genomic features. Quinlan and Hall, Bioinformatics 26:841-842, 2010. <a href="http://bioinformatics.oxfordjournals.org/content/26/6/841.full.pdf+html"><span style="text-decoration: underline;">Publisher Website</span></a></p><h3>Data quality assessment, filtering, and correction</h3><p>SolexaQA: At-a-glance quality assessment of Illumina second-generation sequencing data. Cox et al, BMC Bioinformatics 11:485, 2010. <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956736"><span style="text-decoration: underline;">PubMedCentral</span></a></p><p>TileQC: a system for tile-based quality control of Solexa data. Dolan &amp; Denver, BMC Bioinformatics 9:250, 2008 <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2443380"><span style="text-decoration: underline;">PubMedCentral</span></a> <em>[requires a reference sequence]</em></p><p>Quake: quality-aware detection and correction of sequencing errors. Kelley et al, Genome Biol 11(11):R116, 2010. <a href="http://www.ncbi.nlm.nih.gov/pubmed/21114842"> <span style="text-decoration: underline;">PubMed</span></a></p><p>FastQC: a quality control tool for high-throughput sequence data. <a href="http://www.bioinformatics.bbsrc.ac.uk/projects/fastqc/"><span style="text-decoration: underline;">Home Page</span></a></p><p>FASTX-toolkit: FASTQ/A short-reads pre-processing tools <a href="http://hannonlab.cshl.edu/fastx_toolkit/"><span style="text-decoration: underline;">Home Page</span></a></p><p>Reference-free validation of short read data. Schr&ouml;der et al, PLoS One 5(9):e12681, 2010. <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943903"> <span style="text-decoration: underline;">PubMedCentral</span></a></p><p>Correction of sequencing errors in a mixed set of reads. Salmela, Bioinformatics 26(10):1284, 2010. <a href="http://bioinformatics.oxfordjournals.org/content/26/10/1284.long"><span style="text-decoration: underline;">Full Text</span></a> <em>[includes error correction of SOLiD reads in colorspace]</em></p><p>Repeat-aware modeling and correction of short read errors. Yang et al, BMC Bioinformatics 12(Supp1):S52, 2011 <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044310"> <span style="text-decoration: underline;">PubMedCentral</span></a> <em>[requires a reference sequence]</em></p><p>HiTEC: accurate error correction in high-throughput sequencing data. Ilie et al, Bioinformatics 27(3):295, 2011 <a href="http://bioinformatics.oxfordjournals.org/content/27/3/295.long"><span style="text-decoration: underline;">Full Text</span></a></p><p>Error correction of high-throughput sequencing datasets with non-uniform coverage. Medvedev et al., Bioinformatics 27(13):i137-41, 2011. <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117386"><span style="text-decoration: underline;">PubMedCentral</span></a></p><h3>De novo assembly<span style="text-decoration: underline;"> </span></h3><p>Velvet: algorithms for de novo short read assembly using de Bruijn graphs. Zerbino &amp; Birney, Genome Res 18(5):821-9, 2008. <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2336801">u&gt;PubMedCentral</a></p><p>Assembly of large genomes using second-generation sequencing. Schatz et al, Genome Res 20(9):1165-73, 2010. <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928494"><span style="text-decoration: underline;">PubMedCentral</span></a></p><p>High-quality draft assemblies of mammalian genomes from massively parallel sequence data. Gnerre et al, PNAS 108(4): 1513-18, 2011 <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029755"><span style="text-decoration: underline;">PubMedCentral</span></a></p><p>Genome assembly has a major impact on gene content: a comparison of annotation in two <em>Bos taurus </em> assemblies. Florea&nbsp; et al., PLoS One 6(6):e21400, 2011. <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120881/"><span style="text-decoration: underline;">PubMedCentral</span></a></p><p>Artemis: an integrated platform for visualization and analysis of high-throughput sequence-based experimental data. Carver et al, Bioinformatics 28(4):464 - 469, 2012 <span style="text-decoration: underline;"><a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278759/">PubMedCentral</a></span></p><p>Efficient de novo assembly of large genomes using compressed data structures. Simpson &amp; Durbin, Genome Research 22:549-556, 2012 <span style="text-decoration: underline;"><a href="http://genome.cshlp.org/content/22/3/549.full">Full Text</a></span> <em>[Describes the String Graph Assembler (SGA), which assembled a human genome in less than 6 days using 54 Gb of RAM and a 123-processor compute cluster for calculation of an FM-index of the 1.2 billion reads]</em></p><p>Readjoiner: a fast and memory efficient string graph-based sequence assembler. Gonnella &amp; Kurtz, BMC Bioinformatics 13: 82, 2012 <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507659"><span style="text-decoration: underline;">PubMedCentral</span></a></p><p>Assemblathon 1: A competitive assessment of de novo short read assembly methods. Earl et al, Genome Research 21:2224-2241, 2011 <span style="text-decoration: underline;"><a href="http://genome.cshlp.org/content/early/2011/09/16/gr.126599.111.full.pdf+html">Full Text</a></span></p><h3>Chromatin immunoprecipation analysis: ChIP-seq</h3><p>ChIP-seq: advantages and challenges of a maturing technology. Park, Nat Rev Genet. 10:669-80, 2009 <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191340/"><span style="text-decoration: underline;">PubMed</span></a></p><p>ChIP-seq and Beyond: new and improved methodologies to detect and characterize protein-DNA interactions. Furey, Nat Rev Genet 13: 840&ndash;852, 2012 <a href="http://www.nature.com/nrg/journal/v13/n12/full/nrg3306.html"> <span style="text-decoration: underline;">Publisher Web Site</span></a></p><p>MuMoD: a Bayesian approach to detect multiple modes of protein&ndash;DNA binding from genome-wide ChIP data. Narlikar, Nucleic Acids Res 41:21&ndash;32, 2013 <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592440/"><span style="text-decoration: underline;">PubMed</span></a></p><h3>Transcriptome analysis</h3><h3>Assembly and comparison to genome</h3><p>Full-length transcriptome assembly from RNA-Seq data without a reference genome. Grabherr et al, Nature Biotechnology 29:644 - 652, 2011. <a href="http://www.ncbi.nlm.nih.gov/pubmed/21572440"><span style="text-decoration: underline;">PubMed</span></a> <em>[The software is called <a href="http://trinityrnaseq.sourceforge.net/"><span style="text-decoration: underline;">Trinity</span></a>, and is available on Sourceforge.]</em></p><p>Comprehensive analysis of RNA-Seq data reveals extensive RNA editing in a human transcriptome. Peng et al, Nature Biotechnology 30:253 - 260, 2012. <span style="text-decoration: underline;"><a href="http://www.ncbi.nlm.nih.gov/pubmed/22327324">PubMed</a></span> <em>[Several comments on this paper question whether the reported differences are in fact evidence of editing or are simply sequencing errors - the authors stand by their conclusions, but the controversy demonstrates the importance of robust data analysis methods.] </em></p><p>Optimization of de novo transcriptome assembly from next-generation sequencing data. Surget-Groba &amp; Montoya-Burgos, Genome Res 20(10):1432-40, 2010. <a href="http://genome.cshlp.org/content/20/10/1432.long"><span style="text-decoration: underline;">Full Text</span></a></p><p>Rnnotator: an automated <em>de novo</em> transcriptome assembly pipeline from stranded RNA-Seq reads. Martin et al, BMC Genomics 11:663, 2010 <a href="http://www.biomedcentral.com/1471-2164/11/663"><span style="text-decoration: underline;">Full Text</span></a></p><p><em>De novo</em> assembly and analysis of RNA-seq data. Robertson et al, Nature Methods 7:909-912, 2010 <a href="http://www.nature.com/nmeth/journal/v7/n11/full/nmeth.1517.html"><span style="text-decoration: underline;">Full Text</span></a> <em>[describes Trans-ABySS, a pipeline to use the ABySS parallel assembler for de novo transcriptome analysis]</em></p><h3>Differential expression analysis</h3><p>R-SAP: a multi-threading computational pipeline for the characterization of high-throughput RNA-sequencing data. Mittal &amp; McDonald, Nucleic Acids Res, 2012 <span style="text-decoration: underline;"><a href="http://nar.oxfordjournals.org/content/early/2012/01/28/nar.gks047.long">Full Text</a></span></p><p>Targeted RNA sequencing reveals the deep complexity of the human transcriptome. Mercer et al, Nature Biotechnology 30:99 - 104, 2012 <span style="text-decoration: underline;"><a href="http://www.nature.com/nbt/journal/v30/n1/full/nbt.2024.html"> Publisher Website</a></span></p><p>Differential gene and transcript expression analysis of RNA-Seq experiments with TopHat and Cufflinks. Trapnell et al, Nature Protocols 7:562 - 578, 2012 <span style="text-decoration: underline;"><a href="http://www.nature.com/nprot/journal/v7/n3/full/nprot.2012.016.html"> Publisher Website</a></span></p><p>Characterization and improvement of RNA-Seq precision in quantitative transcript expression profiling. Łabaj et al, Bioinformatics 27:i383 - i391, 2011 <span style="text-decoration: underline;"><a href="http://bioinformatics.oxfordjournals.org/content/27/13/i383.full.pdf+html"> Full Text</a></span></p><p>Improving RNA-Seq expression estimates by correcting for fragment bias. Roberts et al, Genome Biol 12:R22, 2011 <span style="text-decoration: underline;"><a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3129672/">PubMed Central</a></span></p><p>Cloud-scale RNA-sequencing differential expression analysis with Myrna. Langmead et al, Genome Biol 11:R83, 2010 <a href="http://genomebiology.com/2010/11/8/R83"><span style="text-decoration: underline;">Full Text</span></a></p><p>From RNA-seq reads to differential expression results. Oshlack et al, Genome Biol 11(12):220, 2010 <a href="http://genomebiology.com/content/11/12/220"><span style="text-decoration: underline;">Full Text</span></a></p><p>DEGseq: an R package for identifying differentially expressed genes from RNA-seq data. Wang et al., Bioinformatics. 26(1):136-8. 2010 <a href="http://www.ncbi.nlm.nih.gov/pubmed/19855105"><span style="text-decoration: underline;"> PubMed</span></a></p><p>DEseq: Differential expression analysis for sequence count data. Anders and Huber, Genome Biology 11:R106, 2010 <a href="http://genomebiology.com/2010/11/10/R106"><span style="text-decoration: underline;">Full Text</span></a></p><p>edgeR: a Bioconductor package for differential expression analysis of digital gene expression data. Robinson et al., Bioinformatics 26(1):139-40 2010 <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796818"> <span style="text-decoration: underline;">PubMedCentral</span></a></p><p>Two-stage Poisson model for testing RNA-seq data. Auer and Doerge, SAGMB 10(1), article 26 <a href="http://www.bepress.com/sagmb/vol10/iss1/art26/"><span style="text-decoration: underline;">Full Text</span></a></p><p>Experimental design, preprocessing, normalization and differential expression analysis of small RNA sequencing experiments. McCormick et al., Silence2(1):2, 2011 <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055805"><span style="text-decoration: underline;">PubMedCentral</span></a></p><p>RNA-Seq gene expression estimation with read mapping uncertainty. Li et al, Bioinformatics 26:493-500, 2010 <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820677">PubMedCentral</a> <em>[describes the RSEM software package]</em></p><h3>Comparing genomes and assemblies; variant detection<span style="text-decoration: underline;"> </span></h3><p>Versatile and open software for comparing large genomes. Kurtz et al, Genome Biol (5(2):R12, 2004. <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC395750"><span style="text-decoration: underline;">PubMedCentral</span></a> <em>[describes the MUMmer software for full-genome alignment &amp; comparisons]</em></p><p>Searching for SNPs with cloud computing. Langmead et al, Genome Biol 10(11):R134, 2009 <a href="http://genomebiology.com/content/10/11/R134"><span style="text-decoration: underline;">Full Text</span></a></p><p>Calling SNPs without a reference sequence. Ratan et al, BMC Bioinformatics 11:130, 2010 <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851604"><span style="text-decoration: underline;">PubMedCentral</span></a></p><p>Microindel detection in short-read sequence data. Krawitz et al, Bioinformatics 26(6):722-9, 2010. <a href="http://bioinformatics.oxfordjournals.org/content/26/6/722.long"><span style="text-decoration: underline;">Full Text</span></a></p><p>vipR: variant identification in pooled DNA using R. Altmann et al., Bioinformatics 27: i77-i84, 2011. <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117388"><span style="text-decoration: underline;">PubMedCentral</span></a></p><p>Geoseq: a tool for dissecting deep-sequencing datasets. Gurtowski et al, BMC Bioinformatics 11:506, 2010. <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972303/"><span style="text-decoration: underline;">PubMedCentral</span></a> <em>[Geoseq is a web service that allows searching deep sequencing datasets with a reference sequence of a gene of interest]</em></p><p>Detecting and annotating genetic variations using the HugeSeq pipeline. Lam et al, Nature Biotechnology 30:226 - 229, 2012 <span style="text-decoration: underline;"><a href="http://www.nature.com/nbt/journal/v30/n3/full/nbt.2134.html">Publisher Website</a></span>, <span style="text-decoration: underline;"><a href="http://hugeseq.snyderlab.org/">Home Page</a></span></p><p>Genome-wide LORE1 retrotransposon mutagenesis and high-throughput insertion detection in <em>Lotus japonicus</em>. Urbański et al, Plant J 64:731-741, 2012. <span style="text-decoration: underline;"><a href="http://onlinelibrary.wiley.com/doi/10.1111/j.1365-313X.2011.04827.x/abstract">Publisher Website</a></span> <em>[This paper describes a 2-dimensional pooling strategy with barcoding to allow use of Illumina sequencing to screen for retrotransposon insertion mutations, and includes a software package called FSTpoolit for analysis of the resulting sequence reads.]</em></p><h3>Genotyping by sequencing</h3><p>Genome-wide genetic marker discovery and genotyping using next-generation sequencing. Davey et al., Nat Rev Genet 12(7):499-510, 2011 <a href="http://www.ncbi.nlm.nih.gov/pubmed/21681211"><span style="text-decoration: underline;">PubMed</span></a> <em>[A review of methods available at the time]</em></p><p>A robust, simple genotyping-by-sequencing (GBS) approach for high diversity species. Elshire et al., PLoS One 6(5):e19379, 2011. <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087801"><span style="text-decoration: underline;">Full Text</span></a></p><p>Development of high-density genetic maps for barley and wheat using a novel two-enzyme genotyping-by-sequencing approach. Poland et al., PLoS One 7(2): e32253, 2012. <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289635/"><span style="text-decoration: underline;">Full Text</span></a></p><p>Double digest RADseq: an inexpensive method for de novo SNP discovery and genotyping in model and non-model species. Peterson et al, PLoS One 7(5):e37135, . 2012. <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365034/"><span style="text-decoration: underline;">Full Text</span></a></p><p>Imputation of unordered markers and the impact on genomic selection accuracy. Rutkowski et al, G3 3(3):427-39, 2013. <a href="http://www.g3journal.org/content/3/3/427.long"><span style="text-decoration: underline;">Full Text</span></a></p><p>Diversity Arrays Technology (DArT) and next-generation sequencing combined: genome-wide, high-throughput, highly informative genotyping for molecular breeding of <em>Eucalyptus</em>. Sansaloni et al., BMC Proceedings 5(Suppl 7):P54, 2011 <span style="text-decoration: underline;"><a href="http://www.biomedcentral.com/1753-6561/5/S7/P54">Full Text</a></span></p><p>High-throughput genotyping by whole-genome resequencing. Huang et al., Genome Res 19(6):1068-76, 2009. <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694477"><span style="text-decoration: underline;">Full Text</span></a></p><p>Multiplexed shotgun genotyping for rapid and efficient genetic mapping. Andolfatto et al. Genome Res 21(4):610-7, 2011. <a href="http://genome.cshlp.org/content/21/4/610.long"><span style="text-decoration: underline;">Full Text</span></a></p><h3>Restriction-site Associated DNA (RAD) markers</h3><p>Rapid SNP discovery and genetic mapping using sequenced RAD markers. Baird et al, PLoS One 3(10):e3376, 2008 <span style="text-decoration: underline;"><a href="http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0003376">Full Text</a></span></p><p>Linkage mapping and comparative genomics using next-generation RAD sequencing of a non-model organism. Baxter et al., PLoS One 6(4):e19315, 2011. <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082572"><span style="text-decoration: underline;">Full Text</span></a></p><p>Genome evolution and meiotic maps by massively parallel DNA sequencing: spotted gar, an outgroup for the teleost genome duplication. Amores et al, Genetics 188(4):799-808, 2011. <a href="http://www.ncbi.nlm.nih.gov/pubmed/21828280"><span style="text-decoration: underline;"> PubMed</span></a></p><p>Construction and application for QTL analysis of a Restriction-site Associated DNA (RAD) linkage map in barley. Chutimanitsakun et al, BMC Genomics 4; 12:4, 2011. <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023751"><span style="text-decoration: underline;">Full Text</span></a></p><p>RAD tag sequencing as a source of SNP markers in <em>Cynara cardunculus </em>L. Scaglione et al., BMC Genomics 13:3, 2012. <span style="text-decoration: underline;"><a href="http://www.biomedcentral.com/1471-2164/13/3">Full Text</a></span></p><p>Paired-end RAD-seq for de novo assembly and marker design without available reference. Willing et al., Bioinformatics 27(16):2187-93, 2011. <a href="http://bioinformatics.oxfordjournals.org/content/27/16/2187.long"><span style="text-decoration: underline;">Publisher Website</span></a></p><p>Local de novo assembly of RAD paired-end contigs using short sequencing reads. Etter et al., PLOS ONE 6(4): e18561, 2011. <a href="http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0018561"><span style="text-decoration: underline;">Full Text</span></a></p><p>Stacks: building and genotyping loci de novo from short-read sequences. Catchen et al., G3: Genes, Genomes, Genetics, 1:171-182, 2011. <span style="text-decoration: underline;"> Full Text</span>, <a href="http://creskolab.uoregon.edu/stacks/"><span style="text-decoration: underline;">Home Page</span></a></p><p>Rainbow: an integrated tool for efficient clustering and assembling RAD-seq reads. Chong et al, Bioinformatics 28(21):2732-7, 2012. <a href="http://bioinformatics.oxfordjournals.org/content/28/21/2732.long"> <span style="text-decoration: underline;">Publisher Website</span></a></p><p>UK RAD Sequencing Wiki page, with bibliography and RADTools software download <a href="https://www.wiki.ed.ac.uk/display/RADSequencing/Home"><span style="text-decoration: underline;">Home Page</span></a></p><h3>Workspace environments</h3><p><span style="text-decoration: underline;">Papers</span></p><p>Galaxy: a comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences. Goecks et al, Genome Biol 11(8):R86, 2010 <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945788"><span style="text-decoration: underline;">PubMedCentral</span></a></p><p>Galaxy Cloudman: Delivering compute clusters. BMC Bioinformatics 11(Suppl. 12):S4, 2010 <a href="http://www.biomedcentral.com/content/pdf/1471-2105-11-S12-S4.pdf"><span style="text-decoration: underline;">Full Text</span></a></p><p><a href="http://www.broadinstitute.org/gsa/wiki/index.php/The_Genome_Analysis_Toolkit"><span style="text-decoration: underline;">The Genome Analysis Toolkit</span></a>: a MapReduce framework for analyzing next-generation DNA sequencing data. McKenna et al, Genome Res 20(9):1297-303, 2010. <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928508"><span style="text-decoration: underline;">PubMedCentral</span></a></p><p>A framework for variation discovery and genotyping using next-generation DNA sequencing data. DePristo et al., Nat Genet 43(5):491-8, 2011. <a href="http://www.ncbi.nlm.nih.gov/pubmed/21478889"><span style="text-decoration: underline;"> PubMed</span></a></p><p><span style="text-decoration: underline;">Online resources</span></p><p>The <a href="http://cran.r-project.org/"><span style="text-decoration: underline;">R statistical computing</span></a> environment includes<a href="http://www.bioconductor.org/"><span style="text-decoration: underline;"> Bioconductor</span></a>, a specialized set of tools for analysis of microarray and high-throughput sequencing data. Introductory materials from on-line or short workshops are widely available online; examples are <span style="text-decoration: underline;"><a href="http://bioconductor.org/help/course-materials/2012/Evomics2012/Bioconductor-tutorial.pdf">Evomics2012 Bioconductor-tutorial.pdf</a></span>, and <a href="http://bcb.dfci.harvard.edu/%7Eaedin/courses/Bioconductor/"><span style="text-decoration: underline;">Intro to Bioconductor</span></a>. Materials from an advanced course on high-throughput genetic data analysis are at <span style="text-decoration: underline;"><a href="http://bioconductor.org/help/course-materials/2012/SeattleFeb2012/">Seattle 2012 materials</a></span>. Thomas Girke of UC-Riverside has written a very complete set of manuals describing the use of R and Bioconductor for analysis of genomic datasets, available at <a href="http://manuals.bioinformatics.ucr.edu/home/R_BioCondManual">R and Bioconductor Manuals</a>. <br /> <a href="http://cran.r-project.org/manuals.html"><span style="text-decoration: underline;">Manuals</span></a> and contributed <a href="http://cran.r-project.org/other-docs.html"><span style="text-decoration: underline;">documentation</span></a> for R are available at the R-project.org website, and video tutorials are also available on Youtube; those posted by Tutorlol are brief, clear, and to the point. <br /> Materials from a series of mini-courses in R taught in 2010 at UCLA are available:</p><ul>
<li><a href="http://scc.stat.ucla.edu/page_attachments/0000/0141/10S-basicR.pdf">Intro to programming and graphics</a></li>
<li><a href="http://scc.stat.ucla.edu/page_attachments/0000/0143/S10_RProgII.pdf">Data manipulation and functions</a></li>
<li><a href="http://scc.stat.ucla.edu/page_attachments/0000/0185/Graphics_course.pdf">Graphics for exploratory data analysis</a></li>
<li><a href="http://scc.stat.ucla.edu/page_attachments/0000/0147/20100503_IntroStats.pdf">Introductory statistics</a></li>
<li><a href="http://scc.stat.ucla.edu/page_attachments/0000/0188/reg_R_1_09S_slides.pdf">Linear regression</a></li>
</ul><p><a href="http://a-little-book-of-r-for-bioinformatics.readthedocs.org/en/latest/"> <span style="text-decoration: underline;">A Little Book of R for Bioinformatics</span></a> is an on-line resource with information and exercises to provide practice in bioinformatics analysis of DNA sequences and other biological data in R. <br /> Many books on specific topics in R programming are also available through Amazon or other vendors.</p><h3>Cloud computing resources</h3><p>The case for cloud computing in genome informatics. Lincoln Stein, Genome Biol. 11(5):207, 2010 <a href="http://www.ncbi.nlm.nih.gov/pubmed/20441614"><span style="text-decoration: underline;">Pubmed</span></a></p><p>Galaxy Cloudman: delivering cloud compute clusters. Afgan et al, BMC Bioinformatics <span style="text-decoration: underline;">11</span>(Suppl 12):S4, 2010 <a href="http://www.biomedcentral.com/1471-2105/11/S12/S4"><span style="text-decoration: underline;">Full Text</span></a></p><p><a href="http://cloudbiolinux.com/">CloudBioLinux</a> is an open-source project that provides a bioinformatics Linux system for cloud computing, pre-configured with a variety of software tools installed and ready to use.</p><p>A <a href="https://github.com/chapmanb/cloudbiolinux/blob/master/doc/intro/gettingStarted_CloudBioLinux.pdf?raw=true"><span style="text-decoration: underline;">tutorial</span></a> on getting started with CloudBioLinux on the Amazon Web Services Elastic Compute Cloud (EC2)</p><p><a href="http://userwww.service.emory.edu/%7Eeafgan/content/ppt/EnisAfgan_BOSC_2010.pdf"><span style="text-decoration: underline;">Deploying Galaxy on the Cloud</span></a>  slides from a presentation by Enis Afgan (Emory University) at the <br /> &nbsp;Bioinformatics Open Source Conference in Boston, July 2010</p><p>A <a href="http://screencast.g2.bx.psu.edu/cloud/"><span style="text-decoration: underline;"> screencast</span></a> that provides a step-by-step guide to starting a Galaxy cluster in the EC2 environment</p><p>A <a href="https://bitbucket.org/galaxy/galaxy-central/wiki/cloud"><span style="text-decoration: underline;">webpage</span></a> that has the same information in text form, and is the basis for the screencast</p><p>The iPlant Collaborative, an NSF-funded project to create computational resources for plant biology research, provides access to cloud computing resources through <span style="text-decoration: underline;"><a href="http://www.iplantcollaborative.org/discover/atmosphere">Atmosphere</a></span></p><p>SeqWare Query Engine: storing and searching sequence data in the cloud. OConnor et al, BMC Bioinformatics <strong>11</strong>(Suppl 12)<strong>:</strong>S2, 2010 <a href="http://www.biomedcentral.com/1471-2105/11/S12/S2"><span style="text-decoration: underline;">Full Text</span></a></p><p>An overview of the Hadoop/MapReduce/HBase framework and its current applications in bioinformatics. Taylor, BMC Bioinformatics <strong>11</strong>(Suppl 12)<strong>:</strong>S1, 2010 <a href="http://www.biomedcentral.com/1471-2105/11/S12/S1"><span style="text-decoration: underline;">Full Text</span></a></p><h3>Links to Linux command-line tutorials and resources</h3><p>Tutorials for AWK, a powerful tool for handling data tables</p><ul>
<li>A set of <a href="http://people.bu.edu/scottm/AWK.NOTES"><span style="text-decoration: underline;">awk notes</span></a> from Boston University</li>
<li>Bruce Barnett's <a href="http://www.grymoire.com/Unix/Awk.html"><span style="text-decoration: underline;">awk tutorial</span></a></li>
<li>Greg Goebel's <a href="http://www.vectorsite.net/tsawk.html"><span style="text-decoration: underline;">awk tutorial</span></a></li>
<li><a href="http://teaching.software-carpentry.org/2013/01/16/1433/"><span style="text-decoration: underline;">Executing an awk command from R</span></a> to simplify data exploratory analysis, from Lex Nederbragt</li>
</ul><p>Tutorials for bash shell scripting</p><ul>
<li>A <a href="http://www.linuxconfig.org/bash-scripting-tutorial"><span style="text-decoration: underline;">tutorial</span></a> at linuxconfig.org</li>
<li>A <a href="http://www.hypexr.org/bash_tutorial.php"><span style="text-decoration: underline;">Getting Started With Bash</span></a> tutorial at hypexr.org</li>
<li>Mendel Cooper's <a href="http://tldp.org/LDP/abs/html/"><span style="text-decoration: underline;">Advanced Bash Shell-Scripting Guide</span></a></li>
</ul><p>Tutorials for sed, the command-line stream editor</p><ul>
<li>A <a href="http://www.panix.com/%7Eelflord/unix/sed.html"><span style="text-decoration: underline;">tutorial</span></a> at Rutgers</li>
<li>Peteris Krumins claims to have the <a href="http://www.catonmat.net/blog/worlds-best-introduction-to-sed/"><span style="text-decoration: underline;"> World's Best Introduction to Sed</span></a>; take a look and judge for yourself.</li>
<li>Bruce Barnett's <a href="http://www.grymoire.com/Unix/Sed.html"><span style="text-decoration: underline;">sed tutorial</span></a>.</li>
</ul><h3>Links to other useful sites</h3><p>The<a href="http://seqanswers.com/"><span style="text-decoration: underline;"> SEQanswers</span></a> online community has forums on several topics related to sequencing; the bioinformatics forum is the most active.</p><p>The SEQanswers <span style="text-decoration: underline;"><a href="http://seqanswers.com/wiki/Software">Software Wiki</a></span> is a list of software for analysis of sequencing data</p><p><a href="http://biostar.stackexchange.com/">Biostar</a> is another online community for questions and answers on bioinformatics and computational genomics.</p><p>Information on file formats used by the University of California - Santa Cruz Genome Browser is on the <a href="http://genome.ucsc.edu/FAQ/FAQformat"><span style="text-decoration: underline;"> FAQ list</span></a></p><p>A manual for the Integrated Genome Browser visualization tool is <a href="http://wiki.transvar.org/confluence/display/igbman/Home"><span style="text-decoration: underline;">here</span></a></p><p>Course materials for a short course entitled <a href="http://bioconductor.org/help/course-materials/2010/SeattleIntro/"><span style="text-decoration: underline;">Introduction to R and Bioconductor</span></a>, held in Seattle in Dec 2010</p><p><a href="http://great.stanford.edu/"><span style="text-decoration: underline;">Genomic Regions Enrichment of Annotations Tool</span></a> - A web service to test for over-representation of specific ontology categories among genes near ChIP-seq peaks</p><p><a href="http://www.animalgenome.org/bioinfo/resources/nextgensoft.html"><span style="text-decoration: underline;">Next-gen-seq software</span></a> - a list of software packages, both commercial and open-source, related to analysis of deep sequencing datasets</p><p><a href="http://www.cbcb.umd.edu/software/"><span style="text-decoration: underline;">Software</span></a> from the Center for Bioinformatics and Computational Biology, University of Maryland - many useful programs, all open-source</p><p><a href="http://bioinformatics.psb.ugent.be/plaza/"><span style="text-decoration: underline;"> PLAZA</span></a>: a comparative genomics resource to study gene and genome evolution in plants; described by Proost et al, Plant Cell 21:3718, 2010 <a href="http://www.plantcell.org/content/21/12/3718.full"><span style="text-decoration: underline;">Full Text</span></a></p><p>The European Bioinformatics Institute provides tools <a href="http://www.ebi.ac.uk/Tools/rcloud/"><span style="text-decoration: underline;">ArrayExpressHTS</span><span style="text-decoration: underline;"> and R-Cloud</span></a> for analysis of transcriptome data</p>]]></description>
	<dc:creator>Rahul Nayak</dc:creator>
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