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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/19090?offset=940</link>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/pages/view/36392/protein-protein-interaction-sites-predictions</guid>
	<pubDate>Wed, 25 Apr 2018 04:53:20 -0500</pubDate>
	<link>https://bioinformaticsonline.com/pages/view/36392/protein-protein-interaction-sites-predictions</link>
	<title><![CDATA[Protein-Protein Interaction Sites Predictions !]]></title>
	<description><![CDATA[<p><span>The study of Protein&ndash;Protein Interactions (PPIs) has a crucial role in biology, medicine and the pharmaceutical industry. PPIs can be investigated from two aspects: The interaction partners of a specific protein and the amino acid residues participating in a given PPI. Information about a protein&rsquo;s interaction partners allows scientists to construct protein interaction networks, such as signaling pathways, which in turn facilitate the understanding of many biological and clinical observations.&nbsp;</span></p><p><span>Following are the list of tools commonly used to PPIs predictions:</span></p><p>Protein-Protein Interaction Sites</p><p><a href="http://pipe.scs.fsu.edu/ppisp.html" target="_blank">PPISP</a></p><p>A consensus neural network method for predicting protein-protein interaction sites</p><p><a href="http://biunit.naist.jp/homcos/" target="_blank">HOMCOS</a></p><p>A server to predict interacting protein pairs and interacting sites by homology modeling of complex structures</p><p><a href="http://prism.ccbb.ku.edu.tr/hotpoint/" target="_blank">HotPOINT</a></p><p>Prediction of protein interfaces using an empirical model</p><p><a href="http://cubic.bioc.columbia.edu/services/isis/" target="_blank">ISIS</a></p><p>Prediction of interaction hotspots from sequence</p><p><a href="http://kfc.mitchell-lab.org/" target="_blank">KFC server</a></p><p>Automated decision-tree approach to predicting protein-protein interaction hot spots</p><p><a href="http://pipe.scs.fsu.edu/meta-ppisp.html" target="_blank">meta-PPISP</a></p><p>A meta server for predicting protein-protein interaction sites. meta-PPISP is built on three individual web servers:&nbsp;<a href="https://bip.weizmann.ac.il/toolbox/structure/binding.htm#cons">cons-PPISP</a>,&nbsp;<a href="https://bip.weizmann.ac.il/toolbox/structure/binding.htm#pin">PINUP</a>, and&nbsp;<a href="https://bip.weizmann.ac.il/toolbox/structure/binding.htm#pro">Promate</a></p><p><a href="http://www.molsoft.com/oda.html" target="_blank">ODA</a></p><p>Identification of optimal surface patches with the lowest docking desolvation energy values</p><p><a href="http://sparks.informatics.iupui.edu/PINUP/" target="_blank">PINUP</a></p><p>Protein binding site prediction with an empirical scoring function</p><p>Other Sites (DNA, RNA, Metals)</p><p><a href="http://ligin.weizmann.ac.il/~lpgerzon/mbs4/mbs.cgi" target="_blank">CHED</a>&nbsp;</p><p>Web server for predicting soft metal binding sites in proteins</p><p><a href="http://cssb.biology.gatech.edu/skolnick/webservice/DBD-Hunter/" target="_blank">DBD-Hunter</a></p><p>A knowledge-based method for the prediction of DNA-protein interactions</p><p><a href="http://pipe.scs.fsu.edu/displar.html" target="_blank">DISPLAR</a></p><p>Given the structure of a protein known to bind DNA, the method predicts residues that contact DNA using neural network method</p><p><a href="http://idbps.tau.ac.il/" target="_blank">iDBPs</a></p><p>Predicts DNA binding proteins for proteins with known 3D structure.</p><p><a href="http://pfp.technion.ac.il/" target="_blank">PFplus</a></p><div style="text-align: left;">A tool for extracting and displaying positive electrostatic patches on protein surfaces which can be indicative of nucleic acid binding interfaces.</div>]]></description>
	<dc:creator>Poonam Mahapatra</dc:creator>
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<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/36508/mitobim-mitochondrial-baiting-and-iterative-mapping</guid>
	<pubDate>Tue, 08 May 2018 04:15:25 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/36508/mitobim-mitochondrial-baiting-and-iterative-mapping</link>
	<title><![CDATA[MITObim - mitochondrial baiting and iterative mapping]]></title>
	<description><![CDATA[<p>This document contains instructions on how to use the MITObim pipeline described in Hahn et al. 2013. The full article can be found&nbsp;<a href="http://nar.oxfordjournals.org/content/41/13/e129" title="MITObim full article at NAR">here</a>. Kindly cite the article if you are using MITObim in your work. The pipeline was originally developed for&nbsp;<span>Illumina</span>&nbsp;data, but thanks to the versatility of the MIRA assembler, MITObim supports in principle also data from the&nbsp;<span>Iontorrent</span>,&nbsp;<span>454</span>&nbsp;and&nbsp;<span>PacBio</span>&nbsp;sequencing platforms.</p>
<p>Below you can find a few basic tutorials for how to run MITObim and I encorage you to give them a try with the testdata that comes with this Repo, just to make sure everything is running smoothly on your system. It'll only take a few minutes and will potentially safe you a lot of time down the line.</p>
<p>I provide further examples&nbsp;<a href="https://github.com/chrishah/MITObim/tree/master/examples">here</a>&nbsp;as Jupyter notebooks. Get in touch if you feel like sharing your particular MITObim solution and I'd be happy to put it up here, too!</p><p>Address of the bookmark: <a href="https://github.com/chrishah/MITObim" rel="nofollow">https://github.com/chrishah/MITObim</a></p>]]></description>
	<dc:creator>Rahul Nayak</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/26587/last</guid>
	<pubDate>Wed, 09 Mar 2016 14:27:01 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/26587/last</link>
	<title><![CDATA[LAST]]></title>
	<description><![CDATA[<p style="text-align: center;"><img src="http://last.cbrc.jp/lastwebfig.png" alt="sketch of  similar regions in sequences" style="border: 0px;"></p>
<p>LAST can:</p>
<ul>
<li>Handle <strong>big</strong> sequence data, e.g:
<ul>
<li>Compare two vertebrate genomes</li>
<li>Align billions of DNA reads to a genome</li>
</ul>
</li>
<li>Indicate the <a href="http://lastweb.cbrc.jp/about.html">reliability</a> of each aligned column.</li>
<li>Use sequence quality data <a href="http://nar.oxfordjournals.org/content/38/7/e100.abstract">properly</a>.</li>
<li>Compare DNA to proteins, with frameshifts.</li>
<li>Compare PSSMs to sequences</li>
<li>Calculate the likelihood of chance similarities between random sequences.</li>
<li>Do split and spliced alignment.</li>
<li><a href="http://last.cbrc.jp/doc/last-train.html">Train</a> alignment parameters for unusual kinds of sequence (e.g. nanopore).</li>
</ul><p>Address of the bookmark: <a href="http://last.cbrc.jp/" rel="nofollow">http://last.cbrc.jp/</a></p>]]></description>
	<dc:creator>Archana Malhotra</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/43546/introduction-to-phylogenies-in-r</guid>
	<pubDate>Wed, 13 Oct 2021 02:27:21 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/43546/introduction-to-phylogenies-in-r</link>
	<title><![CDATA[Introduction to phylogenies in R]]></title>
	<description><![CDATA[<p><span>R phylogenetics is built on the contributed packages for phylogenetics in R, and there are many such packages. Let's begin today by installing a few critical packages, such as ape, phangorn, phytools, and geiger. To get the most recent CRAN version of these packages, you will need to have R 3.3.x installed on your computer!</span></p><p>Address of the bookmark: <a href="http://www.phytools.org/Cordoba2017/ex/2/Intro-to-phylogenies.html" rel="nofollow">http://www.phytools.org/Cordoba2017/ex/2/Intro-to-phylogenies.html</a></p>]]></description>
	<dc:creator>Abhi</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/44213/bioinformatics-tools-to-explore-ssrs-in-genomes</guid>
	<pubDate>Tue, 07 Mar 2023 13:06:15 -0600</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/44213/bioinformatics-tools-to-explore-ssrs-in-genomes</link>
	<title><![CDATA[Bioinformatics tools to explore SSRs in genomes !]]></title>
	<description><![CDATA[<p>There are several bioinformatics tools that can be used to explore Simple Sequence Repeats (SSRs), which are also known as microsatellites. Here are a few examples:</p><ol>
<li>
<p>MISA: MISA (MIcroSAtellite) is a web-based tool that can identify SSRs in DNA sequences. It can be used to analyze nucleotide sequences from various organisms and can identify perfect, compound, and imperfect SSRs.</p>
</li>
<li>
<p>SSR Locator: SSR Locator is a web-based tool that identifies SSRs in both DNA and RNA sequences. It can identify perfect, compound, and imperfect SSRs, and can also filter out low complexity regions.</p>
</li>
<li>
<p>SciRoKo: SciRoKo is a software tool that can identify SSRs in DNA sequences. It can be used to analyze genomic and transcriptomic sequences from various organisms and can identify perfect, compound, and imperfect SSRs.</p>
</li>
<li>
<p>Primer3: Primer3 is a web-based tool that designs PCR primers for SSRs. It can design primers for perfect and imperfect SSRs, and can be used to design primers for SSRs in various organisms.</p>
</li>
<li>
<p>QDD: QDD (Quick Detection of Duplication) is a software tool that can identify SSRs in DNA sequences and can also identify duplicate loci. It can be used to analyze genomic and transcriptomic sequences from various organisms.</p>
</li>
</ol><p>These are just a few examples of the many bioinformatics tools available for exploring SSRs. Depending on your specific needs and research questions, you may find that other tools are more appropriate for your analysis.</p>]]></description>
	<dc:creator>BioStar</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/34400/ioniser-tools-for-the-quality-assessment-of-data-produced-by-oxford-nanopore%E2%80%99s-minion-sequencer</guid>
	<pubDate>Thu, 23 Nov 2017 10:24:19 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/34400/ioniser-tools-for-the-quality-assessment-of-data-produced-by-oxford-nanopore%E2%80%99s-minion-sequencer</link>
	<title><![CDATA[IONiseR:  tools for the quality assessment of data produced by Oxford Nanopore’s MinION sequencer]]></title>
	<description><![CDATA[<p>This package is intended to provide tools for the quality assessment of data produced by Oxford Nanopore&rsquo;s MinION sequencer. It includes a functions to generate a number plots for examining the statistics that we think will be useful for this task.</p>
<p>However, nanopore sequencing is an emerging and rapidly developing technology. It is not clear what will be most informative. We hope that&nbsp;<code>IONiseR</code>&nbsp;will provide a framework for visualisation of metrics that we haven&rsquo;t thought of, and welcome feedback at&nbsp;<a href="mailto:mike.smith@embl.de" target="_blank">mike.smith@embl.de</a>.</p>
<p>If you&rsquo;re not interested in the quality assement of the raw or event level data, and want to jump straight to the getting FASTQ format files from fast5 files you can go straight to the final section of this document.</p><p>Address of the bookmark: <a href="https://www.bioconductor.org/packages/devel/bioc/vignettes/IONiseR/inst/doc/IONiseR.html" rel="nofollow">https://www.bioconductor.org/packages/devel/bioc/vignettes/IONiseR/inst/doc/IONiseR.html</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/36583/eugi-a-novel-resource-for-studying-genomic-islands-to-facilitate-horizontal-gene-transfer-detection-in-eukaryotes</guid>
	<pubDate>Sat, 12 May 2018 07:26:59 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/36583/eugi-a-novel-resource-for-studying-genomic-islands-to-facilitate-horizontal-gene-transfer-detection-in-eukaryotes</link>
	<title><![CDATA[EuGI: a novel resource for studying genomic islands to facilitate horizontal gene transfer detection in eukaryotes]]></title>
	<description><![CDATA[<p><span>SWGIS v2.0 along with the EuGI database, which houses GIs identified in 66 different eukaryotic species, and the EuGI web-resource, provide the first comprehensive resource for studying HGT in eukaryotes.</span></p>
<p>https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-018-4724-8</p><p>Address of the bookmark: <a href="https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-018-4724-8" rel="nofollow">https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-018-4724-8</a></p>]]></description>
	<dc:creator>Surabhi Chaudhary</dc:creator>
</item>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/38743/molinspiration-broad-range-of-cheminformatics-software-tools-supporting-molecule-manipulation</guid>
	<pubDate>Sun, 20 Jan 2019 05:32:40 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/38743/molinspiration-broad-range-of-cheminformatics-software-tools-supporting-molecule-manipulation</link>
	<title><![CDATA[molinspiration: broad range of cheminformatics software tools supporting molecule manipulation]]></title>
	<description><![CDATA[<p><span>Molinspiration offers&nbsp;</span><a href="https://www.molinspiration.com/products.html">broad range of cheminformatics software tools</a><span>&nbsp;supporting molecule manipulation and processing, including SMILES and SDfile conversion, normalization of molecules, generation of tautomers, molecule fragmentation, calculation of various molecular properties needed in QSAR, molecular modelling and drug design, high quality molecule depiction, molecular database tools supporting substructure and similarity searches. Our products support also fragment-based virtual screening, bioactivity prediction and data visualization. Molinspiration tools are written in Java, therefore can be used practically on any computer platform.</span></p><p>Address of the bookmark: <a href="https://www.molinspiration.com/" rel="nofollow">https://www.molinspiration.com/</a></p>]]></description>
	<dc:creator>BioJoker</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/42570/breeding-insight</guid>
	<pubDate>Wed, 06 Jan 2021 19:49:21 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/42570/breeding-insight</link>
	<title><![CDATA[Breeding Insight]]></title>
	<description><![CDATA[<p><span><span>Breeding Insight&nbsp;at Cornell University will leverage recent improvements in genomics and open source informatics components, and in&nbsp;partnership with small breeding programs, will enable these programs to harness&nbsp;&nbsp;powerful digital tools to accelerate their genetic gains</span></span></p>
<p><span>Breeding Insight is funded by&nbsp;the&nbsp;</span><span><a href="https://www.ars.usda.gov/about-ars/" target="_blank">U.S. Department of Agriculture (USDA) Agricultural Research Service (ARS)</a></span><span>&nbsp;through Cornell University. The USDA ARS delivers scientific solutions to national and global agricultural challenges. As a global leader&nbsp;in agricultural discovery through scientific excellence, ARS is committed to delivering cutting-edge, scientific tools and innovative solutions for American farmers, producers, industry, and communities to support the nourishment and well-being of all people; sustaining our nation&rsquo;s agroecosystems and natural resources; and ensuring the economic competitiveness and excellence of our agriculture.</span></p><p>Address of the bookmark: <a href="https://www.breedinginsight.org/" rel="nofollow">https://www.breedinginsight.org/</a></p>]]></description>
	<dc:creator>BioStar</dc:creator>
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<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/25770/fellowship-doctoral-research-in-biomedical-genomics-including-statistical-genomics</guid>
  <pubDate>Sun, 20 Dec 2015 06:03:43 -0600</pubDate>
  <link></link>
  <title><![CDATA[Fellowship (Doctoral Research In Biomedical Genomics, Including Statistical Genomics)]]></title>
  <description><![CDATA[
<p>Fellowship (Doctoral Research In Biomedical Genomics, Including Statistical Genomics)<br />Eligibility : MSc(Bio-Chemistry, Bio-Informatics, Bio-Tech, Mathematics / Applied Mathematics, Stati, Zoology)<br />Location : Kolkata<br />Last Date : 31 Dec 2015<br />Hiring Process : Written-test</p>

<p>NO: 340/ESTB/ADMN/NIBMG/2015-16 <br />Doctoral Research In Biomedical Genomics, Including Statistical Genomics conduct National Institute of Biomedical Genomics (NIBMG)<br />Information For Students Interested To Pursue Doctoral Research In Biomedical Genomics, Including Statistical Genomics, At The National Institute Of Biomedical Genomics (Nibmg), Kalyan<br />Eligibility conditions for specific areas of research are :<br />Statistical Genomics : An applicant who wishes to pursue research in Statistical Genomics should hold a Master's degree (First class or equivalent) in a relevant discipline (Statistics, Mathematics, Bioinformatics, or a related discipline)<br />Biomedical Genomics : An applicant who wishes to pursue research in any area of biomedical genomics, other than statistical genomics, should hold a Master's degree (First class or equivalent) in a relevant discipline (Biochemistry, Biotechnology, Molecular Biology, Genetics, Zoology, Physiology, or a related discipline)<br />Fellowship : An applicant should have passed the NET conducted by CSIR/UGC/ICMR/DBT within the past ONE year AND should have been awarded a valid Junior Research Fellowship from CSIR, UGC, ICMR, DBT (Category-I only), DST (INSPIRE), NBHM. Preference will be given to candidates with demonstrable research training in the form of summer training or short-term courses in established research laboratories in preparation for a research career in biomedical sciences<br />How to apply<br />Online application will be accepted until 5 PM of December 31, 2015. A formal interview of the short-listed candidates will be held on January 12, 2016</p>

<p>More at http://www.nibmg.ac.in/?q=Career%20Opportunities</p>
]]></description>
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