BOL: Related items

MaxBin: software for binning assembled metagenomic sequences based on an Expectation-Maximization algorithm.

Jit — Mon, 06 Mar 2017 04:03:38 -0600

MaxBin is software for binning assembled metagenomic sequences based on an Expectation-Maximization algorithm. Users can understand the underlying bins (genomes) of the microbes in their metagenomes by simply providing assembled metagenomic sequences and the reads coverage information or sequencing reads. For users' convenience MaxBin will report genome-related statistics, including estimated completeness, GC content and genome size in the binning summary page.

Users can use MEGAN or similar software on MaxBin bins to find the taxonomy of each bin after the binning process is finished.

https://academic.oup.com/bioinformatics/article/32/4/605/1744462/MaxBin-2-0-an-automated-binning-algorithm-to

The most recent version of MaxBin is 2.2, which supports the analysis of coassemblies of multiple samples. It is available at this JBEI downloads sites as well as MaxBin and MaxBin 2.0 sourceforge sites.

Address of the bookmark: http://downloads.jbei.org/data/microbial_communities/MaxBin/MaxBin.html

GroopM: Metagenomic binning toolset

Jit — Tue, 07 Mar 2017 08:59:45 -0600

GroopM is a metagenomic binning toolset. It leverages spatio-temoral
dynamics (differential coverage) to accurately (and almost automatically)
extract population genomes from multi-sample metagenomic datasets.

GroopM is largely parameter-free. Use: groopm -h for more info.

For installation and usage instructions see : http://ecogenomics.github.io/GroopM/

Address of the bookmark: https://github.com/ecogenomics/GroopM

Multigenome assembly

Jit — Tue, 14 Mar 2017 04:41:23 -0500

This project contains scripts and tutorials on how to assemble individual microbial genomes from metagenomes, as described in:

Genome sequences of rare, uncultured bacteria obtained by differential coverage binning of multiple metagenomes

Mads Albertsen, Philip Hugenholtz, Adam Skarshewski, Gene W. Tyson, Kåre L. Nielsen and Per .H. Nielsen

Nature Biotechnology 2013, doi: 10.1038/nbt.2579

See the associated online guide for detailed information.

https://github.com/MadsAlbertsen/multi-metagenome

Address of the bookmark: https://github.com/MadsAlbertsen/multi-metagenome

IBL laboratory

Mon, 12 Aug 2013 02:02:29 -0500

The IBL laboratory focuses on the multi-disciplinary analyses of the global responses of model microorganisms, cyanobacteria (mainly Synechocystis PCC6803) and yeasts (mainly Saccharomyces cerevisae) to environmental stresses triggered by oxidative agents, heavy metals, or drastic changes in nutrients availability. The genome-wide responses studied with the "omics" techniques (transcriptomics, proteomics, metabolomics and genetics) generate a wealth of experimental data, which are processed, archived, integrated and represented as working models through bioinformatics and mathematics.

Link : http://www-dsv.cea.fr/en/instituts/institut-de-biologie-et-de-technologies-de-saclay-ibitec-s/unites-de-recherche/service-de-biologie-integrative-et-genetique-moleculaire-sbigem/laboratoire-de-biologie-integrative-lbi/presentation__1

Bacterial genome assembly !!

Jit — Fri, 05 May 2017 06:11:22 -0500

This tutorial will serve as an example of how to use free and open-source genome assembly and secondary scaffolding tools to generate high quality assemblies of bacterial sequence data. The bacterial sample used in this tutorial will be referred to simply as “Species” since it is live data. This data is paired-end data, meaning that there are forward and reverse reads, which we will designate as Sample_R1.fastq and Sample_R2.fastq, respectively.

https://github.com/jennomics/WorkflowPaper/blob/master/Genome%20Assembly%20and%20Annotation.md

Address of the bookmark: http://bioinformatics.uconn.edu/bacterial-genome-assembly-tutorial/

Computational Proteomics : Lets remember the basics

Jitendra Narayan — Thu, 01 Aug 2013 17:24:20 -0500

I spend some of my valuable time in computational drug designing sector. I remember my initial proteomics days, playing with interactive protein visualization software and dreaming big. Fortunately or unfortunately, I switched to genomics and handling the genomic floods in Petabytes which is expected to be in Brontobytes in coming years. Did I mention Brontobytes ??? Let me call to my server personnel … it gonna tsunami !!!!!

Today, refreshing my old memories I decided to blog about the basic knowledge of biochemistry and computational proteomics skills, but after I found several article on internet saying exactly what I had wanted to say I thought I might as well just redirect BOL's blog readers there instead:

Here is the list of website and videos links which provide a good resource for you basic chemistry need:

http://tecreativ.blogspot.co.uk/2012/09/funny-shortcut-remember-periodic-table.html

This blog have some specific hindi word to remember entire periodic table. I really like

Group 14 (C Si Ge Sn Pb) -> Sentence “Chemistry Sir Gives Sanki Problems”

Sanki is a hindi word which mean crazy :P

I found this link useful as well http://www.wikihow.com/Memorise-the-Periodic-Table

The eagle genomics group provide an element of bioinformatics in periodic tables. Yes you got it, this is not periodic table rather bioinformatics tools with periodicals

http://elements.eaglegenomics.com/

You can also try this video links, which provide you an overview with tricks on periodic tables:

http://www.youtube.com/watch?v=fLSfgNxoVGk

http://www.youtube.com/user/periodicvideos

For drug design educational material, software, tools, databses, viewer, file format and many more stuff at one place http://www.allfordrugs.com/drug-design/ I highly recommend you all computational drug designer to bookmark this page for future studies as well.

I just remember one of my mini project in which I use my flash knowledge (flash .. oh ya flash) to explain amino acids in interactive and user friendly manner. I can’t provide It right now, but promise you to provide a link in near future. I hope that you will enjoy my flashy creative skills :).

Moreover, I found some of very interesting tricks to remember all amino acids chemical formulae on youtube at

http://www.youtube.com/watch?v=gqrWb0fmzQ&list=PL6132651E70BB5575

http://www.youtube.com/watch?v=C2GfoGXfySQ&list=PL6132651E70BB5575

Key points for computer added drug designers?
1. A shortage of biochemistry skills means that you absolutely nowhere in understanding the key concept and do research.
2. Keep handy with complex mathematical formula, before merely running tools or software.
3. Dig it better and deeper guys .. design it.

33rd Annual Convention of Indian Association for Cancer Research from 13th to 15th February 2014

Tue, 27 Aug 2013 10:37:08 -0500

RGCB is organizing the 33rd Annual Convention of Indian Association for Cancer Research from 13th to 15th February 2014 with the theme "Discovery, Innovation and Translation in Cancer Research"

Kindly log on to conference website http://rgcb.res.in/IACR2014 for further details and timely updates and registration. We shall truly appreciate if the same be circulated among your friends, scholars and students encouraging them to participate in the meet.

http://210.212.237.38/iacrconference/

IMTECH Lab

Sun, 15 Sep 2013 09:41:04 -0500

Computer Aided Protein Structure Prediction; Identification of Vaccine
Candidates (T-Epitope prediction); Analysis of Nucleotide/Protein Sequences; Development of Web Server/

Software; Creation of Public Domain Resources in Biology
Present Status::

Developing prediction methods for gene, beta-turn, secondary structure and MHC-binding sites.
Area of Interest ::

Comparison of force field simulations. Analysis of DNA-protein interactions using molecular mechanics methods.Drug Target Identification using in silico biology.

More @ http://www.imtech.res.in/bic/index.php?option=com_content&view=article&id=65

PIs: http://www.imtech.res.in/bic/index.php?option=com_content&view=article&id=69

Eugene V. Koonin Lab

Tue, 09 Jan 2018 05:01:15 -0600

Interested in understanding the evolution of life. To obtain glimpses of such understanding, we employ existing and new methods of computational biology to perform research in several major areas.

https://www.ncbi.nlm.nih.gov/research/groups/koonin/

Taverna Workflow Management System

Madhvan Reddy — Thu, 15 Aug 2013 19:34:32 -0500

Taverna is an open source domain independent Workflow Management System – a suite of tools used to design and execute scientific workflows. Taverna has been created by the myGrid project and is funded through a range of organisations and projects.

The Taverna suite is written in Java and includes the Taverna Engine(used for enacting workflows) that powers both the Taverna Workbench(the desktop client application) and the Taverna Server (which allows remote execution of workflows). Taverna is also available as a Command Line Tool for a quick execution of workflows from a terminal.

Address of the bookmark: http://www.taverna.org.uk/