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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/19980?offset=690</link>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/22430/nrco-vacancies-for-junior-research-fellow-%E2%80%93-pakyong-sikkim</guid>
  <pubDate>Thu, 28 May 2015 19:10:07 -0500</pubDate>
  <link></link>
  <title><![CDATA[NRCO Vacancies For Junior Research Fellow – Pakyong, Sikkim]]></title>
  <description><![CDATA[
<p>Junior Research Fellow<br />Pay Scale:Rs 25,000/-<br />Educational Requirements:MSc (with NET qualification) / M.Tech degree (with or without NET) with minimum 55% marks in Biotechnology/ Bioinformatics/ Molecular Biology or any other related field.<br />Other Qualification:Computer Skills (Linux, Perl, Java, MySQL) with experience in advanced molecular Biology techniques.<br />No of Post: 01<br />How To Apply: Walk-in-Interviews will be held at ICAR-National Research Centre for Orchids,Pakyong 737106, Sikkim for the post of 01 (One) Junior Research Fellow and 01 (One) Project Attendant under Project ‘DBT’s Twinning programme for the NE’ titled “Assessment of chemical and genetic divergence of some fragrant orchids of north-east India for sustainable improvement of community livelihood” as indicated below. The appointment will be on contractual basis and the incumbents shall not have any claim for regular appointment in ICAR.</p>

<p>Details will be available at: http://nrcorchids.nic.in/Employments/Vacancy%20-%20JRF.pdf</p>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/22410/nicolas-corradi-lab</guid>
  <pubDate>Tue, 26 May 2015 16:19:02 -0500</pubDate>
  <link></link>
  <title><![CDATA[Nicolas Corradi Lab]]></title>
  <description><![CDATA[
<p>The goal of our research is to better understand the biology of microbial organisms of significant ecological, veterinary and medical importance.<br />To achieve this goal, our team combines the power of next generation DNA sequencing and  bioinformatics with molecular biology and experimental procedures.</p>

<p>Main research topics:<br />- Comparative and Population Genomics of Plant Symbionts<br />- Parasite Genome Evolution<br />- Experimental Evolution of Microbial Symbionts and Parasites<br />- Phylogenomics of Early Branching Fungi</p>

<p>More at http://corradilab.weebly.com/</p>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/22435/assistant-professor-central-university-of-himachal-pradesh-india</guid>
  <pubDate>Thu, 28 May 2015 19:22:49 -0500</pubDate>
  <link></link>
  <title><![CDATA[Assistant Professor, Central University of Himachal Pradesh, India]]></title>
  <description><![CDATA[
<p>Central University of Himachal Pradesh</p>

<p>PO Box: 21</p>

<p>DHARAMSHALA, DISTRICT KANGRA, HIMACHAL PRADESH – 176215</p>

<p>EMPLOYMENT NOTICE NO.: 02 / 2015</p>

<p>APPOINTMENT TO VARIOUS TEACHING, NON-TEACHING AND OTHER ACADEMIC STAFF POSITIONS</p>

<p>Applications in the prescribed form are invited from the eligible candidates for the following Teaching, Non-Teaching and other Academic Staff positions to be filled up on regular basis: Details of teaching positions:</p>

<p>15. School of Life Sciences</p>

<p>Computational Biology &amp; Bioinformatics</p>

<p>1 (ST - 1) 2 (UR - 2)</p>

<p>Last Date of receipt of applications: 22ND JUNE, 2015</p>

<p>Advertisement:</p>

<p>http://www.cuhimachal.ac.in/download/2015/may-2015/emp-notice-eng/1.%20Employment%20Notice%20No.%2002-2015%20dated%2019.05.2015_for%20Website.pdf</p>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/22520/recruitment-for-6-positions-of-jrf-junior-research-fellow</guid>
  <pubDate>Thu, 04 Jun 2015 15:22:54 -0500</pubDate>
  <link></link>
  <title><![CDATA[RECRUITMENT FOR 6 POSITIONS OF JRF (Junior Research Fellow)]]></title>
  <description><![CDATA[
<p>Institute of Bioresources and Sustainable Development (IBSD), a National Institute of the Department of Biotechnology, Government of India invites applications for 6 positions of JRF for 2015. The main mandate of IBSD is Conservation and Sustainable Utilization of Bioresources for the Socio-economic Development of the North East Region of India, which is a genetic treasure trove of plants, animals and microbial resources. This region falls among the World’s top 10 Biodiversity Hotspots. The broad areas of research are in Plant Bioresources, Microbial Resources, Natural Product Chemistry, Animal Bioresources and Bioinformatics and Database Management. </p>

<p>Minimum qualifications: M.Sc. with minimum 55% for general and OBD Category (55% for SC/St/PH) in the above-mentioned subject areas (viz. Biotechnology, Life Sciences, Microbiology, Botany, Plant Sciences, Chemistry, Zoology, Animal Sciences, Fishery Sciences and any other relevant branches). </p>

<p>Preference will be given to those holding valid CSIR-UGC NET JRF. DBT-JRF, ICAR-JRF, ICMR-JRF and DST-INSPIRE Fellowship while NET/SLET/SET qualified and GATE qualified candidates (90 or above percentile) are also encouraged to apply. Reservations of seats: 15% for SC, 7.5% for ST, 27% for OBC (noncreamy layer) and 3% for Physically Handicapped as per statutory norms. </p>

<p>Selection Procedure: If the number of JRF and INSPIRE qualified candidates is more, selection will be based on interview of the JRF and INSPIRE qualified candidates only. The selected candidates may be registered for Ph.D. in any of the recognized Universities in India. </p>

<p>Application Procedure: Application should be sent in the prescribed application form (available on the IBSD website). The candidate should send the completed and signed form along with self attested copies of all supporting certificates and marksheets along with an application fee of Rs.300/- (For GEN/OBC/PH) &amp; Rs.150/- for (SC/ST), for which a Demand Draft in favour of ‘Institute of Bioresources and Sustainable Development, payable at Imphal, Manipur, should be attached with the application form. Candidates are advised to provide their email ID and mobile number as they would be contacted electronically by the Institute. Duly filled applications (with ‘Application for IBSD PhD Programme’ super scribed on the envelope) should be sent to ‘The Director, Institute of Bioresources and Sustainable Development, Takyelpat, Imphal-795001, Manipur so as to reach on or before 6th of July, 2015. Applications send by email with scan copy of required enclosures will also be accepted and can be sent to director.ibsd@nic.in. However, in such instances, the application will be processed only after the receipt of the mailed hard copies. </p>

<p>Advertisement: http://ibsd.gov.in/jobs/phd_2015/IBSD_JRF_2015.pdf</p>

<p>Application Form : http://ibsd.gov.in/jobs/phd_2015/APPLICATION_FORM.pdf</p>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/22616/research-associate-manit-allahabad-uttar-pradesh</guid>
  <pubDate>Fri, 12 Jun 2015 05:44:38 -0500</pubDate>
  <link></link>
  <title><![CDATA[Research Associate MANIT - Allahabad, Uttar Pradesh]]></title>
  <description><![CDATA[
<p>Applications are invited from Indian nationals for the post of Research Assistant (on contract) in research project entitled “Identification of novel drug targets in Aspergillus fumigatus genome prioritized by essentiality based screening and rational designing of new antifungal compounds” sanction order no. CST/238 dated 12/05/2015 sponsored by Council of Science and Technology U.P. </p>

<p>The duly completed application on prescribed format along with copies of supporting documents must reach to: Office of the Dean (Research &amp; Consultancy), Motilal Nehru National Institute of Technology, Allahabad-211004 on or before 03/07/2015. </p>

<p>The position is purely temporary and will be governed by the funding agency rules &amp; service conditions of Office of the Dean (Research &amp; Consultancy), MNNIT Allahabad. </p>

<p>For detail advertisement see: www.mnnit.ac.in/images/newstories/Advertisement_for_the_post_of_Research_Assistant_in_UPCST_Project_of_Biotechnology_Department.pdf</p>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/22779/research-associate-at-international-centre-for-genetic-engineering-and-biotechnology-icgeb</guid>
  <pubDate>Wed, 17 Jun 2015 18:49:05 -0500</pubDate>
  <link></link>
  <title><![CDATA[Research Associate at International Centre for Genetic Engineering and Biotechnology (ICGEB)]]></title>
  <description><![CDATA[
<p>Research Associate<br />International Centre for Genetic Engineering and Biotechnology (ICGEB)<br />Address: Aruna Asaf Ali Marg, Jawaharlal Nehru University, New Delhi<br />Postal Code: 110067<br />City: New Delhi<br />State: Delhi<br />Qualifications: Experience in many docking softwares and operating systems is essential. Additional experience in bioinformatics and computational biology tools will be useful.<br />Details will be available at: http://www.icgeb.org/vacancies.html<br /> <br />How To Apply: Submit curriculum vitae to: sb.icgeb@gmail.com<br />Last Date: 5 July 2015</p>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/22788/research-associate-bioinformatics-job-position-in-indian-agricultural-statistics-research-institute-iasri-pusa-new-delhi</guid>
  <pubDate>Wed, 17 Jun 2015 20:48:40 -0500</pubDate>
  <link></link>
  <title><![CDATA[Research Associate Bioinformatics job position in Indian Agricultural Statistics Research Institute (IASRI), Pusa, New Delhi]]></title>
  <description><![CDATA[
<p>Research Associate Statistics</p>

<p>Eligibility : M Phil / Phd, MSc</p>

<p>Location : Delhi</p>

<p>Last Date : 27 Jun 2015</p>

<p>Hiring Process : Walk - In<br />Indian Agricultural Statistics Research Institute (IASRI) - Job DetailsDate of posting:03 Jun 15</p>

<p>Research Associate Statisticsjob position in Indian Agricultural Statistics Research Institute (IASRI)<br />on purely contractual temporary basis</p>

<p>Project : “ICAR-Network Project of Transgenic in Crops”</p>

<p>Qualification : Ph.D. in Bioinformatics/ Agricultural Statistics/ Statistics/ Computer Science/ Computer Application/ Life Science/ Biotechnology/ Agricultural Science or equivalent OR Post-Graduation in Bioinformatics/ Agricultural Statistics/ Statistics/ Computer Science/ Computer Application/ Life Science/ Biotechnology/ Agricultural Science or equivalent with 1st Division or 60% marks or equivalent with at least two years of research experience.</p>

<p>No.of Post: 01</p>

<p>Emoluments for RA: Consolidated Rs. 24000/- per month + 30% HRA for Ph.D holders and consolidated Rs. 23000/- per month + 30% HRA for Master Degree.</p>

<p>Age Limit : 40 years<br />How to apply</p>

<p>Walk-in-interview will be held on 27th June 2015, 10.30 A.M at IASRI, Pusa, New Delhi</p>

<p>More at http://iasri.res.in/employment/employment.htm</p>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/22944/icgeb-bioinformatics-research-associate-vacancy</guid>
  <pubDate>Thu, 25 Jun 2015 20:41:00 -0500</pubDate>
  <link></link>
  <title><![CDATA[ICGEB Bioinformatics Research Associate Vacancy]]></title>
  <description><![CDATA[
<p>Research Associate Position at ICGEB, New Delhi with Dr. Amit Sharma</p>

<p>Starting 15th July 2015, the position relates to a project specifically for in silico drug docking, screening, design, optimisation and linkage with active chemists. </p>

<p>Experience in many docking softwares and operating systems is essential. </p>

<p>Additional experience in bioinformatics and computational biology tools will be useful. </p>

<p>Submit curriculum vitae to: sb.icgeb@gmail.com</p>

<p>Closing date: 5 July 2015</p>
]]></description>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/23384/research-scientist-at-dupont</guid>
  <pubDate>Fri, 17 Jul 2015 20:36:17 -0500</pubDate>
  <link></link>
  <title><![CDATA[Research Scientist at DuPONT]]></title>
  <description><![CDATA[
<p>Research Scientist<br />Hyderabad, Telangana<br />Job Description</p>

<p>Job Description</p>

<p>The Global Trait Discovery Informatics (GTDI) group located at the DuPont Knowledge Centre (DKC), Hyderabad, India is currently seeking applications for a highly motivated computational biologist. The GTDI group contributes to research programs in plant biotechnology at the DKC as well as across research centers located in DuPont Pioneer, Johnston, Iowa and at the DuPont Experimental Station in Wilmington, Delaware.</p>

<p>We are looking for candidates who have experience in analysis of high-throughput -omics datasets. The researcher will be primarily responsible for analyzing diverse -omics datatypes, such as transcriptomics, proteomics and metabolomics and actively contribute towards building streamlined solutions.</p>

<p>The candidate will be part of a diverse team of experimental biologists, computational biologists and software developers. A critical aspect of this position involves working with global teams across multiple locations and will require effective project coordination and communication skills. This is an exciting opportunity for candidates with strong data driven skills, who want to work at the interface of computational and experimental biology and contribute towards scientific discovery.</p>

<p>Responsibilities</p>

<p>·Integrate and analyze multiple datatypes in the context of experimental observations with a goal towards formulating testable hypothesis.</p>

<p>·Understanding the research questions from experimental biologists and formulate relevant in silico analyses.</p>

<p>·Establish and implement systematic analysis workflows starting from processing of raw data to biological interpretation.</p>

<p>·Critically analyze a wide variety of experimental data with a view to solving the underlying research questions.</p>

<p>·Identify and generate datasets for scientific testing and evaluation of algorithms.</p>

<p>Qualifications</p>

<p>PhD in computational biology, bioinformatics, population genetics, complex systems, computer sciences or any relevant physical or mathematical sciences, with experience in analyzing diverse -omics datasets.</p>

<p>Job Qualifications</p>

<p>Qualifications</p>

<p>PhD in computational biology, bioinformatics, population genetics, complex systems, computer sciences or any relevant physical or mathematical sciences, with experience in analyzing diverse -omics datasets.</p>

<p>More at http://careers.dupont.com/jobsearch/job-details/research-scientist/006077W-01/</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/33306/ancestral-sequence-reconstruction-asr-or-ancestral-genesequence-reconstructionresurrection-tools-to-study-molecular-evolution</guid>
	<pubDate>Tue, 30 May 2017 04:20:05 -0500</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/33306/ancestral-sequence-reconstruction-asr-or-ancestral-genesequence-reconstructionresurrection-tools-to-study-molecular-evolution</link>
	<title><![CDATA[Ancestral sequence reconstruction (ASR) or ancestral gene/sequence reconstruction/resurrection tools to study molecular evolution]]></title>
	<description><![CDATA[<p><span><strong>Ancestral sequence reconstruction</strong><span>&nbsp;(</span><strong>ASR</strong><span>) &ndash; also known as&nbsp;</span><strong>ancestral gene</strong><span>/</span><strong>sequence reconstruction</strong><span>/</span><strong>resurrection</strong><span>&nbsp;&ndash; is a technique used in the study of&nbsp;</span>molecular evolution<span>. The method consists of the synthesis of an ancestral&nbsp;</span>gene<span>&nbsp;and expression of the corresponding ancestral&nbsp;</span>protein<span>.&nbsp;</span><sup id="cite_ref-thornton_1-0"><a href="https://en.wikipedia.org/wiki/Ancestral_sequence_reconstruction#cite_note-thornton-1"></a></sup><span>The idea of protein 'resurrection' was suggested in 1963 by Pauling and Zuckerkandl.</span><sup id="cite_ref-2"><a href="https://en.wikipedia.org/wiki/Ancestral_sequence_reconstruction#cite_note-2"></a></sup><span>&nbsp;Some early efforts were made in the eighties-nineties, led by the laboratory of&nbsp;</span>Steven A. Benner<span>, showing the potential of this technique &ndash; one that only started to be fulfilled in the post-genomic era.</span><sup id="cite_ref-3"><a href="https://en.wikipedia.org/wiki/Ancestral_sequence_reconstruction#cite_note-3"></a></sup><span>&nbsp;Thanks to the improvement of algorithms and of better sequencing and synthesis techniques, the method was developed further in the early 2000s to allow the resurrection of a greater variety of and much more ancient genes.</span><sup id="cite_ref-4"><a href="https://en.wikipedia.org/wiki/Ancestral_sequence_reconstruction#cite_note-4"></a></sup><span>&nbsp;Over the last decade, ancestral protein resurrection has developed as a strategy to reveal the mechanisms and dynamics of protein evolution.&nbsp;</span></span></p><p><img src="https://upload.wikimedia.org/wikipedia/commons/thumb/e/e4/ASR_phylogeny.png/510px-ASR_phylogeny.png" alt="image" width="610" height="435" style="border: 0px; border: 0px;"></p><p><span>Following are the list of&nbsp;</span><strong style="font-size: 12.8px;">Ancestral /sequence/ reconstruction</strong><span>&nbsp;(</span><strong style="font-size: 12.8px;">ASR</strong><span>) tools:&nbsp;</span></p><p><a href="http://www.bx.psu.edu/miller_lab/car/" target="_blank" title="To inferCars official website"><span>inferCars</span></a></p><p><span><span><span><span><span>Reconstructs contiguous regions of an ancestral genome. Given information about adjacencies between conserved segments in each modern species, our goal is to infer segment order in the ancestral genome. To get a clean and precise statement of the problem, we formalize it using graph theory. We develop an algorithm that identifies a most parsimonious scenario for the history of each individual adjacency, although the whole-genome prediction is not guaranteed to optimize traditional measures like the number of breakpoints. We introduce weights to the graph edges to model the reliability of each adjacency.</span></span></span></span></span></p><p><span><span><a href="http://paleogenomics.irmacs.sfu.ca/ANGES/" target="_blank" title="To ANGES official website">ANGES</a>:</span><a href="http://paleogenomics.irmacs.sfu.ca/ANGES/" target="_blank" title="To ANGES official website">reconstructing ANcestral GEnomeS maps</a></span></p><p><span><span><span><span><span><span>A suite of Python programs that allows reconstructing ancestral genome maps from the comparison of the organization of extant-related genomes. ANGES can reconstruct ancestral genome maps for multichromosomal linear genomes and unichromosomal circular genomes. It implements methods inspired from techniques developed to compute physical maps of extant genomes.</span></span></span></span></span></span></p><p><a href="http://virulence.molgen.mpg.de/cocos/" target="_blank" title="To Cocos official website"><span>Cocos</span></a></p><p><span><span><span><span><span><span><span>Constructs phylogenies of multi-domain proteins. With a given species tree and domain phylogenies, the procedure infers the composition of ancestral multi-domain proteins. Cocos implements and extend a suggested algorithmic approach by Behzadi and Vingron in an easy-to-use program. Such method could be applied to reconstruction of partial homologous units such as bacterial operons or protein complexes.</span></span></span></span></span></span></span></p><p><a href="https://github.com/msrosenberg/MySSP" target="_blank" title="To MySSP official website"><span>MySSP</span></a></p><p><span><span><span><span><span><span><span><span>Constructs an initial DNA sequence at the root of the tree and simulates evolution across the tree using a variety of common models of DNA evolution. MySSP is a program for the simulation of DNA sequence evolution across a phylogenetic tree. It is designed for large-scale studies, including simulation of multiple replicates and outputs sequences into NEXUS, MEGA, or FASTA formats. MySSP has a fairly simple graphical user interface (GUI) for basic use, but also has a specialized batch script interpreter to allow for more complicated or large-scale simulations.</span></span></span></span></span></span></span></span></p><p><span><span><a href="http://www.cs.cmu.edu/~ckingsf/software/parana/" target="_blank" title="To PARANA official website">PARANA</a>:&nbsp;</span><a href="http://www.cs.cmu.edu/~ckingsf/software/parana/" target="_blank" title="To PARANA official website">Parsimonious Ancestral Reconstruction And Network Analysis</a></span></p><p><span><span><span><span><span><span><span><span><span>Performs parsimony based inference of ancestral biological networks. Given multiple extant networks and phylogenetic information relating extant nodes, PARANA finds a parsimonious set of ancestral interaction events (edge gains and losses) which explain the extant networks. The framework adopted by PARANA is able to represent network evolution under models that support gene duplication and loss and independent interaction gain and loss. The method works on both directed and undirected networks and can incorporate asymmetric interaction gain and loss costs. In contrast to previous approaches, PARANA does not require knowing the relative ordering of unrelated duplication events and thus, works on phylogenetic trees even where branch lengths are not provided.</span></span></span></span></span></span></span></span></span></p><p><span><span><a href="http://www-labs.iro.umontreal.ca/~mabrouk/" target="_blank" title="To GapAdj official website">GapAdj</a>:&nbsp;</span><a href="http://www-labs.iro.umontreal.ca/~mabrouk/" target="_blank" title="To GapAdj official website">Gapped Adjacencies</a></span></p><p><span><span><span><span><span><span><span><span><span><span>A synteny-based method that is flexible enough to handle a model of evolution involving whole genome duplication events, in addition to rearrangements, gene insertions, and losses. Ancestral relationships between markers are defined in term of Gapped Adjacencies, i.e. pairs of markers separated by up to a given number of markers. It improves on a previous restricted to direct adjacencies, which revealed a high accuracy for adjacency prediction, but with the drawback of being overly conservative, i.e. of generating a large number of contiguous ancestral regions (CARs).</span></span></span></span></span></span></span></span></span></span></p><p><a href="http://ancestors.bioinfo.uqam.ca/"><span><span><span><span><span><span><span><span><span><span>ANCESTOR</span></span></span></span></span></span></span></span></span></span></a></p><p><span><span><span><span><span><span><span><span><span><span><span>A web server allowing one to easily and quickly perform the last three steps of the ancestral genome reconstruction procedure. Ancestors implements several alignment algorithms, an indel maximum likelihood solver and a context-dependent maximum likelihood substitution inference algorithm. The results presented by the server include the posterior probabilities for the last two steps of the ancestral genome reconstruction and the expected error rate of each ancestral base prediction.</span></span></span></span></span></span></span></span></span></span></span></p><p><a href="http://bioinfo.lifl.fr/procars/" target="_blank" title="To ProCARs official website"><span>ProCARs</span></a></p><p>Reconstructs ancestral gene orders as contiguous ancestral regions (CARs) with a progressive homology-based method. ProCARs runs from a phylogeny tree (without branch lengths needed) with a marked ancestor and a block file. This homology-based method is based on iteratively detecting and assembling ancestral adjacencies, while allowing some micro-rearrangements of synteny blocks at the extremities of the progressively assembled CARs. The method starts with a set of blocks as the initial set of CARs, and detects iteratively the potential ancestral adjacencies between extremities of CARs, while building up the CARs progressively by adding, at each step, new non-conflicting adjacencies that induce the less homoplasy phenomenon. The species tree is used, in some additional internal steps, to compute a score for the remaining conflicting adjacencies, and to detect other reliable adjacencies, in order to reach completely assembled ancestral genomes.</p><p><a href="http://fastml.tau.ac.il/" target="_blank" title="To FastML official website"><span>FastML</span></a></p><p>A user-friendly tool for the reconstruction of ancestral sequences. FastML implements various novel features that differentiate it from existing tools: (i) FastML uses an indel-coding method, in which each gap, possibly spanning multiples sites, is coded as binary data. FastML then reconstructs ancestral indel states assuming a continuous time Markov process. FastML provides the most likely ancestral sequences, integrating both indels and characters; (ii) FastML accounts for uncertainty in ancestral states: it provides not only the posterior probabilities for each character and indel at each sequence position, but also a sample of ancestral sequences from this posterior distribution, and a list of the k-most likely ancestral sequences; (iii) FastML implements a large array of evolutionary models, which makes it generic and applicable for nucleotide, protein and codon sequences; and (iv) a graphical representation of the results is provided, including, for example, a graphical logo of the inferred ancestral sequences.</p><p><a href="http://rth.dk/resources/maxAlike/" target="_blank" title="To maxAlike official website"><span>maxAlike</span></a></p><p>Reconstructs a genomic sequence for a specific taxon based on sequence homologs in other species. The input is a multiple sequence alignment and a phylogenetic tree that also contains the target species. For this target species, the algorithm computes nucleotide probabilities at each sequence position. Consensus sequences are then reconstructed based on a certain confidence level.</p><p><span><span><a href="http://www.geneorder.org/server.php" target="_blank" title="To MLGO official website">MLGO</a>:&nbsp;</span><a href="http://www.geneorder.org/server.php" target="_blank" title="To MLGO official website">Maximum Likelihood for Gene Order Analysis</a></span></p><p>A web tool for the reconstruction of phylogeny and/or ancestral genomes from gene-order data. MLGO was designed for analysis of large-scale genomic changes including not only rearrangements but also gene insertions, deletions and duplications. MLGO can be used to infer a phylogeny from genome rearrangement and gene order data, and can also obtain an estimation of ancestral genomes, given an input tree. MLGO takes the advantage of binary encoding on gene-order data, supports a fairly general model of genomic evolution (rearrangements plus duplications, insertions, and losses of genomic regions), and successfully accommodates itself into the framework of maximized likelihood.</p><p>Image Reference : Wiki</p>]]></description>
	<dc:creator>Jit</dc:creator>
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