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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/2041?offset=100</link>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/32465/tetra-nucleotide-analysis</guid>
	<pubDate>Thu, 04 May 2017 05:07:41 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/32465/tetra-nucleotide-analysis</link>
	<title><![CDATA[Tetra-Nucleotide Analysis]]></title>
	<description><![CDATA[<p>A tetra-nucleotide is a fragment of DNA sequence with 4 bases (e.g. AGTC or TTGG). Pride&nbsp;<em>et al.</em>&nbsp;(2003) showed that the frequency of tetra-nucleotides in bacterial genomes contain useful, albeit weak, phylogenetic signals. Even though tetra-nucleotide analysis (TNA) utilizes the information of whole genome, it is evident that it cannot replace other alignment-based phylogenetic methods such as&nbsp;<a href="https://chunlab.wordpress.com/orthoani/">OrthoANI</a>&nbsp;or&nbsp;16S rRNA phylogeny. However, TNA can be useful for&nbsp;phylogenetic characterization when whole genome or 16S rRNA gene information is not available. For example, a partial genomic fragment obtained from a metagenome can be identified by TNA (Teeling&nbsp;<em>et al.</em>, 2004). TNA is also fast enough that it can be&nbsp;used&nbsp;as a search engine against a large genome database.</p><p>Address of the bookmark: <a href="https://chunlab.wordpress.com/tetra-nucleotide-analysis/" rel="nofollow">https://chunlab.wordpress.com/tetra-nucleotide-analysis/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/1149/system-biologist-at-millennium-software-productions-india-private-limited</guid>
  <pubDate>Fri, 19 Jul 2013 09:43:53 -0500</pubDate>
  <link></link>
  <title><![CDATA[System Biologist at Millennium Software productions India Private Limited]]></title>
  <description><![CDATA[
<p>Millennium Software productions India Private Limited</p>

<p>www.cytosolve.com</p>

<p>Post - System Biologist</p>

<p>Job Description: Role of system biology is to design quantitative models of bimolecular networks and to study interactions between the components of biological systems, and how these interactions give rise to the function and behavior of that system (Enzyme, metabolites and pathway).</p>

<p>Qualification : B.Tech or M.Sc in Bioinformatics</p>

<p>Required Skills:</p>

<p>1) Basic knowledge of cell signaling pathways, chemical/enzyme kinetics, and differential equation based modeling approach.<br />2) Previous laboratory experience could be an advantage<br />3) Good Communication skills.</p>

<p>santhiya.ram@mproductions.com and 044-42946555.</p>
]]></description>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/32496/bioinformatician-at-23andme</guid>
  <pubDate>Sat, 06 May 2017 17:57:39 -0500</pubDate>
  <link></link>
  <title><![CDATA[Bioinformatician at 23andMe]]></title>
  <description><![CDATA[
<p>23andMe’s mission is to help people access, understand, and benefit<br />from the human genome. We are a group of passionate individuals excited<br />to push the boundaries of what’s possible to help turn genetic insight<br />into better health and personal understanding.</p>

<p>Our Research Team prides itself on driving cutting edge, industrial-scale<br />science to make an impact that belies the team’s size, in an environment<br />and culture that fosters creativity, innovation, collaboration, and fun.</p>

<p>More than 80% of our customers consent to participate in research, and as<br />a result of their participation, we have one of the largest recontactable,<br />genotyped, and phenotyped research cohorts in the world. The scope and<br />breadth of our vision means that most of the methods and tools necessary<br />to unlock the potential of this unique resource for discovery have yet<br />to be developed.</p>

<p>Our science has garnered the respect of many members of the<br />broader scientific community. For a list of our publications, see<br />www.23andme.com/publications/for-scientists/.</p>

<p>Join us! Visit our Careers page (www.23andMe.com/careers) to learn more<br />about these open positions:</p>

<p>•	Scientist, Research Communications<br />•	Bioinformaticist<br />•	Computational Biologist, Ancestry R&amp;D<br />•	Scientist/Senior Scientist, Statistical Genetics<br />•	Scientist/Senior Scientist, Survey Methodology<br />•	Scientist/Senior Scientist, Health R&amp;D<br />•	Senior Computational Biologist<br />•	Biostatistician</p>

<p>pfontanillas@23andme.com</p>
]]></description>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/1217/studentship-at-bioinformatics-infrastructure-facility-bif-department-of-biotechnology-alagappa-university</guid>
  <pubDate>Fri, 02 Aug 2013 10:33:54 -0500</pubDate>
  <link></link>
  <title><![CDATA[Studentship at Bioinformatics Infrastructure Facility (BIF), Department of Biotechnology, Alagappa University]]></title>
  <description><![CDATA[
<p>WALK IN INTERVIEW</p>

<p>A walk-in Interview for the following position tenable at the Bioinformatics Infrastructure Facility (BIF), Department of Biotechnology, Alagappa University will be held at the Department of Biotechnology, Science Campus, Alagappa University, Karaikudi 630 004 on 03.08.2013 (Saturday) at 12:30 PM. This national facility is funded by the Department of Biotechnology, Ministry of Science and Technology, Government of India, New Delhi. The main objectives of the Centre involve teaching and research activities in bioinformatics/biotechnology.</p>

<p>1. Studentship (One Post):</p>

<p>Stipend : Rs. 5000 p.m. (consolidated)</p>

<p>Qualification: M.Sc., in Bioinformatics/Biotechnology/Biophysics/Biochemistry/<br />Life Sciences</p>

<p>Interested candidates are encouraged to send their Curriculum Vitae by email to alagappauniv.btisnet@nic.in in advance. On the day of interview, the candidates must produce original certificates in proof of their educational qualification and experience and a recommendation letter from the Head of the Department/Institution where last studied/worked. Candidates who have already passed the required Degree alone are eligible to appear for interview. No TA&amp;DA will be given for attending the interview.</p>

<p>Advertisement: http://www.alagappabiotech.org/Notification.pdf</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/32633/a-post-assembly-genome-improvement-toolkit-pagit-to-obtain-annotated-genomes-from-contigs</guid>
	<pubDate>Fri, 12 May 2017 10:50:29 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/32633/a-post-assembly-genome-improvement-toolkit-pagit-to-obtain-annotated-genomes-from-contigs</link>
	<title><![CDATA[A Post-assembly genome-improvement toolkit (PAGIT) to obtain annotated genomes from contigs]]></title>
	<description><![CDATA[<p>PAGIT addresses the need for software to generate high quality draft genomes. It is based on a series of programs that we developed:</p>
<p><a href="https://sourceforge.net/projects/abacas/files/">ABACAS</a>, that is able to contiguate contigs from a de novo assembly against a closely related reference.</p>
<p><a href="https://sourceforge.net/projects/image2/files/">IMAGE</a>, an iterative approach for closing gaps in assembled genomes using mate pair information. It is able to close gaps left open by the assembler in a draft genome, even when using the same data sets as used by the original assembler.</p>
<p><a href="http://icorn.sourceforge.net/">iCORN</a>, that enables errors in the consensus sequence to be corrected by iteratively mapping reads to the current assembly. An improved version, especially correction Pacfic Bioscience assemblies (PacBio) can be found&nbsp;<a href="ftp://ftp.sanger.ac.uk/pub4/resources/software/pagit/ICORN2/icorn2.V0.95.tgz">here</a>.</p>
<p><a href="https://ratt.svn.sourceforge.net/svnroot/ratt">RATT</a>, a tool to transfer the annotation from a reference genome, or an earlier assembly, onto the latest assembly.</p>
<p>PAGIT bundles these software and makes them more accessible for users.</p><p>Address of the bookmark: <a href="http://www.sanger.ac.uk/science/tools/pagit" rel="nofollow">http://www.sanger.ac.uk/science/tools/pagit</a></p>]]></description>
	<dc:creator>Abhimanyu Singh</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/2042/ngs-course-medical-genomics-scheduled-for-17-20-september-2013-in-uz-leuven-belgium</guid>
	<pubDate>Mon, 12 Aug 2013 12:08:24 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/2042/ngs-course-medical-genomics-scheduled-for-17-20-september-2013-in-uz-leuven-belgium</link>
	<title><![CDATA[NGS course Medical Genomics, scheduled for 17-20 September 2013 in UZ Leuven (Belgium).]]></title>
	<description><![CDATA[<p>This course is open to all students and postdocs and registration for all academic participants is free of charge. To help us in organizing the course, please register online via http://gc.uzleuven.be where the preliminary program is also available.</p><p>This course is organized with support from the IAP &ldquo;Belgian Medical Genomics Initiative&rdquo;, SymBioSys and the Genomics Core.</p><p>For inquiries, please email Ms Narcisse Opdekamp ( narcisse.opdekamp@uzleuven.be ).</p><p>More at &gt;&gt;&nbsp;<a href="http://gc.uzleuven.be/">http://gc.uzleuven.be/</a></p>]]></description>
	<dc:creator>Poonam Mahapatra</dc:creator>
</item>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/32719/download-assemblies-from-ncbi</guid>
	<pubDate>Mon, 15 May 2017 06:02:32 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/32719/download-assemblies-from-ncbi</link>
	<title><![CDATA[Download assemblies from NCBI]]></title>
	<description><![CDATA[<p>A new &ldquo;Download assemblies&rdquo; button is now available in the&nbsp;<a href="https://www.ncbi.nlm.nih.gov/assembly" target="_blank">Assembly</a>&nbsp;database. This makes it easy to download data for multiple genomes without having to write scripts.</p><p>For example, you can run a search in Assembly and use check boxes (see left side of screenshot below) to refine the set of genome assemblies of interest. Then, just open the &ldquo;Download assemblies&rdquo; menu, choose the source database (<a href="https://www.ncbi.nlm.nih.gov/genbank/" target="_blank">GenBank</a>&nbsp;or&nbsp;<a href="https://www.ncbi.nlm.nih.gov/refseq/" target="_blank">RefSeq</a>), choose the file type, and start the download. An archive file will be saved to your computer that can be expanded into a folder containing your selected genome data files.</p><p><img src="https://ncbiinsights.files.wordpress.com/2017/05/download_button.jpg?w=584" alt="image" width="584" height="444" style="border: 0px; border: 0px;"></p><p>&nbsp;</p><p>More at&nbsp;https://ncbiinsights.ncbi.nlm.nih.gov/2017/05/08/genome-data-download-made-easy/</p>]]></description>
	<dc:creator>Bulbul</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/1469/prime-minister%E2%80%99s-100k-genome-project</guid>
	<pubDate>Thu, 08 Aug 2013 09:40:39 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/1469/prime-minister%E2%80%99s-100k-genome-project</link>
	<title><![CDATA[Prime Minister’s 100k Genome Project]]></title>
	<description><![CDATA[<p>Genomics Ebgland is destined to sequence 100,000 patients over the next five year in England.&nbsp; A landmark project by british government.</p><p>Genomics England will play a key role in building on the UK&rsquo;s long track record as leader in medical science advances to push the boundaries by unlocking the power of DNA data. The UK will become the first ever country to introduce this technology in its mainstream health system &ndash; leading the global race for better tests, better drugs and above all better, more personalised care.</p><p>http://www.genomicsengland.co.uk/100k-genome-project/</p>]]></description>
	<dc:creator>Jitendra Narayan</dc:creator>
</item>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/32849/car-reconstructing-contiguous-regions-of-an-ancestral-genome</guid>
	<pubDate>Thu, 18 May 2017 05:24:01 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/32849/car-reconstructing-contiguous-regions-of-an-ancestral-genome</link>
	<title><![CDATA[CAR: Reconstructing Contiguous Regions of an Ancestral Genome]]></title>
	<description><![CDATA[<div id="abstract-1">
<p id="p-5">We describe a new method for predicting the ancestral order and orientation of those intervals from their observed adjacencies in modern species. We combine the results from this method with data from chromosome painting experiments to produce a map of an early mammalian genome that accounts for 96.8% of the available human genome sequence data. The precision is further increased by mapping inversions as small as 31 bp. Analysis of the predicted evolutionary breakpoints in the human lineage confirms certain published observations but disagrees with others. Although only a few mammalian genomes are currently sequenced to high precision, our theoretical analyses and computer simulations indicate that our results are reasonably accurate and that they will become highly accurate in the foreseeable future. Our methods were developed as part of a project to reconstruct the genome sequence of the last ancestor of human, dogs, and most other placental mammals;</p>
</div><p>Address of the bookmark: <a href="http://www.bx.psu.edu/miller_lab/car/" rel="nofollow">http://www.bx.psu.edu/miller_lab/car/</a></p>]]></description>
	<dc:creator>Abhimanyu Singh</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/1491/2013-nextgen-genomics-bioinformatics-technologies-ngbt-conference-new-delhi-india</guid>
  <pubDate>Thu, 08 Aug 2013 16:21:16 -0500</pubDate>
  <link></link>
  <title><![CDATA[2013 NextGen Genomics &amp; Bioinformatics Technologies (NGBT) Conference, New Delhi, INDIA]]></title>
  <description><![CDATA[
<p>2013 NextGen Genomics &amp; Bioinformatics Technologies (NGBT) Conference</p>

<p>SciGenom Research Foundation (SGRF) and Institute of Genomics and Integrative Biology (IGIB) are pleased to host the Next-Generation Sequencing and Bioinformatics for Genomics &amp; Healthcare conference.</p>

<p>In the ten years since the first human reference genome was completed for US$3 billion the sequencing technologies have radically changed leading to great reduction in sequencing cost. Today a human genome can be sequenced for under US$ 5000 in less than two weeks. It is expected that by the end of 2015 the cost of sequencing a human genome will drop to below thousand dollars. The next generation sequencing technologies over the past five years have enabled a large number of genomic studies that impact human health and disease. Also, this has made possible the growth of microbial, animal and plant genomics studies. While the data production has increased at a rapid pace challenges remain in analyzing and understanding the data. The conference will cover the next generation sequencing (NGS) technologies, bioinformatics for NGS and applications of NGS in many areas including personalized medicine.</p>

<p>For more info : http://www.scigenomconferences.com/2013/default.php</p>
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