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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/20585?offset=740</link>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/37618/snakemake%E2%80%94a-scalable-bioinformatics-workflow-engine</guid>
	<pubDate>Sun, 02 Sep 2018 16:32:42 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/37618/snakemake%E2%80%94a-scalable-bioinformatics-workflow-engine</link>
	<title><![CDATA[Snakemake—a scalable bioinformatics workflow engine]]></title>
	<description><![CDATA[<p><span>Snakemake is a workflow engine that provides a readable Python-based workflow definition language and a powerful execution environment that scales from single-core workstations to compute clusters without modifying the workflow.&nbsp;</span></p><p>Address of the bookmark: <a href="https://bioconda.github.io/recipes/snakemake/README.html" rel="nofollow">https://bioconda.github.io/recipes/snakemake/README.html</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/39469/introduction-to-bioinformatics</guid>
	<pubDate>Wed, 05 Jun 2019 14:58:11 -0500</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/39469/introduction-to-bioinformatics</link>
	<title><![CDATA[Introduction to Bioinformatics]]></title>
	<description><![CDATA[<p><img src="https://edu.t-bio.info/wp-content/uploads/2017/07/Introduction-Course-Title-11.jpg" alt="Introduction to Bioinformatics Course" width="600" height="315.6" style="vertical-align: top; border: 0px; border: 0px;"></p><p>Introduction to bioinformatics is a course for biologists and clinicians that would like to learn more about the way bioinformatics is used in healthcare, biotech and pharmaceuitcal industry as well as basic research. The course covers many of the topics transformed by the emergence of big data and computational technologies. To learn more about the course, visit:&nbsp;<a href="https://edu.t-bio.info/course/introduction-bioinformatics/">https://edu.t-bio.info/course/introduction-bioinformatics/</a></p>]]></description>
	<dc:creator>eliabrodsky</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/40881/liu-lab</guid>
  <pubDate>Tue, 04 Feb 2020 06:27:02 -0600</pubDate>
  <link></link>
  <title><![CDATA[Liu Lab]]></title>
  <description><![CDATA[
<p>Shirley is a computational biologist with expertise in cancer epigenetics. Her research focuses on algorithm development and integrative mining from big data generated on microarrays, massively parallel sequencing, and other high throughput techniques to model the specificity and function of transcription factors, chromatin regulators and lncRNAs in tumor development, progression, drug response and resistance.</p>

<p>https://liulab-dfci.github.io/software/</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/41202/biocontainers</guid>
	<pubDate>Thu, 20 Feb 2020 05:29:46 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/41202/biocontainers</link>
	<title><![CDATA[BioContainers]]></title>
	<description><![CDATA[<p><span>BioContainers is a community-driven project that provides the infrastructure and basic guidelines to create, manage and distribute bioinformatics packages (e.g conda) and containers (e.g docker, singularity). BioContainers is based on the popular frameworks&nbsp;</span><a href="https://conda.io/">Conda</a><span>,&nbsp;</span><a href="https://www.docker.com/">Docker</a><span>&nbsp;and&nbsp;</span><a href="https://www.sylabs.io/docs/">Singularity</a><span>.</span></p><p>Address of the bookmark: <a href="https://biocontainers.pro/#/" rel="nofollow">https://biocontainers.pro/#/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/42236/bioinformatics-focused-postdoctoral-fellow</guid>
  <pubDate>Fri, 23 Oct 2020 05:52:52 -0500</pubDate>
  <link></link>
  <title><![CDATA[Bioinformatics-focused postdoctoral fellow]]></title>
  <description><![CDATA[
<p>Jason Thomas Ladner currently recruiting for a bioinformatics-focused postdoctoral<br />fellow to join the group at the Pathogen and Microbiome Institute,<br />Northern Arizona University (http://www7.nau.edu/ladnerlab/). This<br />will be a multi-year, NIH-funded position focused on the development and<br />utilization of a novel platform for highly multiplexed antiviral serology,<br />which utilizes high-throughput sequencing technology.</p>

<p>To apply:<br />https://hr.peoplesoft.nau.edu/psp/ph92prta/EMPLOYEE/HRMS/c/HRS_HRAM.HRS_APP_SCHJOB.GBL?Page=HRS_APP_JBPST&amp;Action=U&amp;FOCUS=Applicant&amp;SiteId=1&amp;JobOpeningId=604999&amp;PostingSeq=1</p>

<p>For more information, feel free to contact me: jason.ladner@nau.edu</p>
]]></description>
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<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/42664/common-bioinformatics-interview-questions</guid>
	<pubDate>Sat, 23 Jan 2021 06:07:50 -0600</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/42664/common-bioinformatics-interview-questions</link>
	<title><![CDATA[Common Bioinformatics Interview Questions !]]></title>
	<description><![CDATA[<p>The possibility of an interview for a bioinformatics position in the life sciences may be very disquieting, but the same concerns emerge time and again in my experience. So, it is exceedingly worthwhile to plan for future bioinformatics interview questions. Doing this will really give you the advantage in obtaining the position.</p><p>The following 5 questions are those that I have heard many times during the job-search process. There is no reason for not planning responses in such situations.</p><p><strong>1. Tell Us About Yourself</strong><br />This is a very typical opener in interviews. It's a perfect question to ask, and getting something planned will really help you concentrate and ease in the conversation. However, you need to make sure that your response is applicable to the job you're interviewing.<br />It's probably better to keep your answer professional. Try to include these in the answer as well: where did your love of science and bioinformatics come from? How the heck did you end up in this field? Why programming and scripting ?</p><p><strong>2. What is your plan for your bioinformatics career? / How do you look at yourself in five years? / How are your personal objectives to accomplish these goals / What are the plan for your research fundings ?</strong></p><p>Your CV/resume has already impressed the selection panel if you have been invited for an interview. The questions from the bioinformatics interview team provide an incentive for you to market yourself and illustrate the work in question with the most appropriate knowledge.</p><p><strong>3. What do you understand about the job description/What would your suggested research path be if you were a successful candidate?</strong><br />Summarize the specifics of the advertised bioinformatics position in your own words. Follow on with some suggestions of how you want to extend your research and create your own projects within the community.</p><p><strong>4. Will you work as a group or do you want to work on your own?</strong><br />This requirement can vary from jobs to job, so when addressing, be alert. A company/research PI may need a bioinformatician that is able to work on a single project autonomously, or they may need a person who can help direct and organize a team. In your response, refer to the job description.</p><p><strong>5. What particular methods have you used to date with your experiments?</strong><br />You might have experience with all the laboratory techniques described in the job description, but stress the ones you highly experienced with. Highlight your professional abilities and stress that you are extremely capable of mastering new techniques with others ...</p><p>At the end of the day, remember that you're questioning the jury as well as they're interviewing you. You will ought to think of any questions you would like the interview panel to pose. This indicates that you have done your homework and serious about the position.</p><p>All the best for your future job interview.</p>]]></description>
	<dc:creator>Jit</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/43044/kanthida-lab</guid>
  <pubDate>Wed, 28 Apr 2021 02:27:22 -0500</pubDate>
  <link></link>
  <title><![CDATA[Kanthida Lab !]]></title>
  <description><![CDATA[
<p>Research Interest: </p>

<p>Bioinformatics </p>

<p>High-throughput and high-dimensional data analysis</p>

<p>Microbiome data analysis (Main focus)</p>

<p>Next-generation and third-generation sequencing data analysis for genomics</p>

<p>Gene expression data analysis</p>

<p>Machine learning for biological data</p>

<p>Biomarkers identification </p>

<p>Database and web-application for biological data</p>

<p>More at <br />https://sites.google.com/mail.kmutt.ac.th/kanthida-k/home?authuser=0</p>
]]></description>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/14191/scalpel</guid>
	<pubDate>Wed, 20 Aug 2014 02:07:58 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/14191/scalpel</link>
	<title><![CDATA[Scalpel]]></title>
	<description><![CDATA[<p>A team from Cold Spring Harbor Laboratory has released an algorithm, called Scalpel, for finding insertions and deletions in next generation sequencing data sets. Scalpel, which is open source and <a href="http://scalpel.sourceforge.net/" title="available for download">available for download</a> on SourceForge,&nbsp;<span>outperformed the popular tools GATK HaplotypeCaller and SOAPindel in test runs on both simulated and real whole human exomes.</span></p><p>Like other indel callers, Scalpel works by performing <em>de novo</em>&nbsp;assembly of regions of interest, so that misalignment to the reference genome cannot obscure the presence of an insertion or deletion. Scalpel's innovation is to repeatedly check its assembly before comparing to the reference genome, to account for simple sequence repeats that are a regular source of error in indel calling. When Scalpel assembles an exon, it collects reads that map to that exon (including partial matches), splits them into k-mers, and creates a de Bruijn graph to span the exon; however, if it detects repeats in the map, it iteratively increases the size of the k-mers by one base until the repeats are eliminated. This ensures that the final assembly of the exon is highly accurate while minimizing compute time.</p><p>The Cold Spring Harbor team's validation of Scalpel, <a href="http://www.nature.com/nmeth/journal/vaop/ncurrent/full/nmeth.3069.html" title="published over the weekend in Nature Methods">published over the weekend in <em>Nature Methods</em></a>, compares Scalpel's performance on a live whole exome against HaplotypeCaller and SOAPindel. The donor is an individual with serious neurological disorders, which may be linked to a high incidence of indels. One thousand indels from this individual's exome, called by one or more of the informatics pipelines, were selected for focused resequencing. This resequencing revealed a 77% true positive rate for Scalpel calls, dramatically better than the rates for either of the competing tools; Scalpel performed especially well with indels longer than five base pairs, a traditional weak point for indel callers.</p><p>Finally, the authors demonstrate Scalpel's use on a large set of genetic data from nearly 600 families who donated samples to the Simons Simplex Collection, a project of the Simons Foundation Autism Research Initiative. Scalpel found a very high enrichment for indels in children affected by autism, compared with their unaffected siblings, a pattern that persisted even after excluding common variants.</p>]]></description>
	<dc:creator>Shruti Paniwala</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/43323/biostarhandbook</guid>
	<pubDate>Fri, 27 Aug 2021 01:31:01 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/43323/biostarhandbook</link>
	<title><![CDATA[biostarhandbook]]></title>
	<description><![CDATA[<p>Nice book collection for bioinformatician ... highly recommended.</p><p>Address of the bookmark: <a href="https://www.biostarhandbook.com/" rel="nofollow">https://www.biostarhandbook.com/</a></p>]]></description>
	<dc:creator>Neel</dc:creator>
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<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/44400/pevzner-lab</guid>
  <pubDate>Thu, 02 Nov 2023 05:39:26 -0500</pubDate>
  <link></link>
  <title><![CDATA[Pevzner Lab !]]></title>
  <description><![CDATA[
<p>The laboratory works on genome sequencing, immunoproteogenomics, antibiotics sequencing, and comparative genomics - computational technologies that enabled new applications and allowed scientists to attack biological problems that remained beyond the reach of previous techniques.</p>

<p>https://bioalgorithms.ucsd.edu/research4.html</p>
]]></description>
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