How does SEX-DETector work?

SEX-DETector does not require prior sequencing of a reference genome: the same sequencing data can be used for the assembly and for the mapping of the reads. A full documentation on the pipeline can be found here.

• we recommend Trinity for the assembly.
• Trinity components should be merged with cap3. Our code to perform the merging is available here.
• We recommend BWA for mapping of the reads.
• When the mapping has been perfomed, the individuals need to be genotyped; SEX-DETector takes files produced by Reads2snp (which is available for download on the PopPhyl website) as input.

Address of the bookmark: http://lbbe.univ-lyon1.fr/-SEX-DETector-.html?lang=eg

Mulan (http://mulan.dcode.org/), a novel method and a network server for comparing multiple draft and finished-quality sequences to identify functional elements conserved over evolutionary time. Mulan brings together several novel algorithms: the TBA multi-aligner program for rapid identification of local sequence conservation, and the multiTF program for detecting evolutionarily conserved transcription factor binding sites in multiple alignments. In addition, Mulan supports two-way communication with the GALA database; alignments of multiple species dynamically generated in GALA can be viewed in Mulan, and conserved transcription factor binding sites identified with Mulan/multiTF can be integrated and overlaid with extensive genome annotation data using GALA.

Address of the bookmark: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC540288/

Applications are invited from candidates for the temporary positions on contractual basis for academic arrangement in the School of Biotechnology, SKUAST-J:

3 Assistant Professor (Bioinformatics) (01)

Rs. 25000/- per month for Ph.D. and Rs. 20000/- per month for M. Sc. (Fixed)

High second class M.Sc. degree (55 % marks) in Biotechnology/ Bioinformatics

NET in concerned subject/ Ph.D. & Teaching/ research experience in Bioinformatics/ Computational Biology as evident from documents /publications

The application should reach the office of Coordinator, School of Biotechnology, SKUAST-J, Chatha, Jammu-180009 (J&K) along with attested copies of the certificates on or before 10.01.2019 through registered post only.

More Info: http://skuast.org/site/Templates%20HTML/jobs/2018/ap-sbt-21-12-2018.pdf

Online applications are invited from eligible & interested candidates for the following Teaching/Non-Teaching posts. Applications must be submitted online from 10.4.2018 to 30.4.2018 through the link available on the university website www.mdurohtak.ac.in

Applicants must read the instructions carefully before proceeding to fill the form. The detailed information/instructions/eligibility criteria are available on the university website www.mdurohtak.ac.in

Budgeted:

Teaching posts:-

Botany: Assistant Professor-1(UR); Biochemistry: Associate Professor-1(UR), Assistant Professor-2(UR-1, SC-1); Centre for Biotechnology: Assistant Professor-1(UR); Centre for Bioinformatics: Associate Professor-1(UR), Assistant Professor-1(SC); Chaudhary Ranbir Singh Institute of Social & Economic Change: Assistant Professor-1(UR); Computer Science & Applications: Assistant Professor-4(UR-3,SC-1); Environmental Science: Assistant Professor-1(UR); Food Technology: Assistant Professor:-2(UR-1, SC-1), Genetics: Professor-1(UR); Microbiology: Assistant Professor-1(SC); Pharmaceutical Sciences: Assistant Professor-1{ESM(UR)}; Physics: Assistant Professor-5{UR-1, SC-2, BC(A)-1, ESM(UR)-1}

Interested candidates may email their resume along with a cover letter to careers@arraygen.com

Official website: http://www.arraygen.com/

About 8,000 years ago, the gene EGLN1 changed by a single DNA base pair. Today, a relatively short time later on the scale of human history, 88 percent of Tibetans have the genetic variation, and it was virtually absent from closely related lowland Asians. The findings indicate the genetic variation endows its carriers with an advantage.

In those without the adaptation, low oxygen caused their blood to become thick with oxygen-carrying red blood cells, an attempt to feed starved tissues, which could cause long-term complications such as heart failure. The researchers found that the newly identified genetic variation protected Tibetans by decreasing the over-response to low oxygen.

Reference: http://www.nature.com/nature/journal/v512/n7513/abs/nature13408.html

Finally, I find the underlying R code in a file created by GrapheR. For more details read also the package vignette, which is available in English, French and German!

More at http://pythonhosted.org/pybedtools/

A powerful toolset for genome arithmetic.http://code.google.com/p/bedtools/

Please visit our site at www.arraygen.com