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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/2261?offset=30</link>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/25993/hoffman-lab</guid>
  <pubDate>Tue, 12 Jan 2016 02:47:41 -0600</pubDate>
  <link></link>
  <title><![CDATA[Hoffman Lab]]></title>
  <description><![CDATA[
<p>They develop machine learning techniques to better understand chromatin biology. These models and algorithms transform high-dimensional functional genomics data into interpretable patterns and lead to new biological insight.</p>

<p>https://www.pmgenomics.ca/hoffmanlab/</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/pages/view/918/data-mining-in-bioinformatics</guid>
	<pubDate>Tue, 16 Jul 2013 03:21:28 -0500</pubDate>
	<link>https://bioinformaticsonline.com/pages/view/918/data-mining-in-bioinformatics</link>
	<title><![CDATA[Data Mining in Bioinformatics]]></title>
	<description><![CDATA[<p>Data mining, the extraction of hidden predictive information from large databases. Data mining is becoming an increasingly important tool to transform this data into information. It is commonly used in a wide range of profiling practices, such as marketing, surveillance, fraud detection and scientific discovery. Data Mining for Bioinformatics enables researchers to meet the challenge of mining vast amounts of biomolecular data to discover real knowledge. In other words, you&rsquo;re a bioinformatician, and data has been dumped in your lap. Find the patterns, trend, answers, or what ever meaningful knowledge the data is hiding. They scour databases for hidden patterns, finding predictive information that experts may miss because it lies outside their expectations.This page Covering theory, algorithms, and methodologies, as well as data mining technologies. Unfortunately life is never simple. In molecular biology, it&rsquo;s becoming more common to generate reams of data then ask someone in bioinformatics to produce an answer. This is exploratory data analysis, one of the most difficult things to do well. Especially if you&rsquo;re thrown in at the deep end.</p><p><strong>Data mining commonly involves four classes of tasks:</strong></p><ul>
<li>Classification - Arranges the data into predefined groups. For example, an email program might attempt to classify an email as legitimate or spam. Common algorithms include decision tree learning, nearest neighbor, naive Bayesian classification and neural networks.</li>
<li>Clustering - Is like classification but the groups are not predefined, so the algorithm will try to group similar items together.</li>
<li>Regression - Attempts to find a function which models the data with the least error.</li>
<li>Association rule learning - Searches for relationships between variables. For example a supermarket might gather data on customer purchasing habits. Using association rule learning, the supermarket can determine which products are frequently bought together and use this information for marketing purposes. This is sometimes referred to as market basket analysis.</li>
<li>From experience, I can say that is one of the most frustrating positions to be in. Data mining is a huge field and can easily be bewildering for a beginner. However, high through-put techniques in molecular biology require, more and more, that bioinformatics is required to interpret the data. Furthermore, people working in bioinformatics generally come from computer science, or biology backgrounds. Data mining, however, involves statistics to one degree or another, which means entering a field that is may not be your strong point.</li>
<li>Excel is fine for creating graphs. If you&rsquo;re serious about data mining though, you&rsquo;ll need something more heavy weight. I use R, free, and with good data mining packages such as vegan and labdsv. For beginners R can be impenetrable, I recommend this book an introduction to R as well as the underlying statistics.</li>
<li>Any of us can rush head on into a land of support vector machines, hidden markov models and neural networks. But coming back to the first point, what are you trying to prove? Always question what are you doing, how does it fit in to the wider picture? Try to regularly review, and keep track of where you are going? This will prevent you from falling into data mining despair.</li>
</ul><p><strong>Data Mining Resources on the net:</strong><br /><br />A laboratory of data mining and bioinformatics is headed by Prof. Ambuj Singh. There are currently seven graduate students in the research group. Our research focuses on image informatics and scalable querying and mining of graphs.For more detail visit:&nbsp;<a href="http://www.cs.ucsb.edu/~dbl/">http://www.cs.ucsb.edu/~dbl/</a></p><p>Here are the materials (Lecture notes) from several past courses on data mining and/or Web mining by Stanford: For detail visit:&nbsp;<a href="http://infolab.stanford.edu/~ullman/mining/mining.html">http://infolab.stanford.edu/~ullman/mining/mining.html</a><br />Statistical Data Mining Tutorial Slides by Andrew Moore The following links point to a set of tutorials on many aspects of statistical data mining, including the foundations of probability, the foundations of statistical data analysis, and most of the classic machine learning and data mining algorithms. For detail visit:&nbsp;<a href="http://www.autonlab.org/tutorials/">http://www.autonlab.org/tutorials/</a></p><p>A tutorial on Introduction to Data Mining for Discovering hidden value in your data warehouse:<a href="http://www.thearling.com/text/dmwhite/dmwhite.htm">http://www.thearling.com/text/dmwhite/dmwhite.htm</a>&nbsp;<br />Wiki Links:&nbsp;<a href="http://en.wikipedia.org/wiki/Data_mining">http://en.wikipedia.org/wiki/Data_mining</a><br />Bioinformatics with Clementine&nbsp;<a href="http://www.spss.ch/upload/1051192224_inseratClemBio.pdf">http://www.spss.ch/upload/1051192224_inseratClemBio.pdf</a>&nbsp;<br />Causal Data Mining in Bioinformatics by Ioannis Tsamardinos:&nbsp;<a href="http://www.forth.gr/ics/bmi/In_the_News/2007/EN69-4.pdf">http://www.forth.gr/ics/bmi/In_the_News/2007/EN69-4.pdf</a></p><p>Report on ACM Text Mining in Bioinformatics (TMBIO 006)&nbsp;<a href="http://www.sigir.org/forum/2007J/2007j_sigirforum_song.pdf">http://www.sigir.org/forum/2007J/2007j_sigirforum_song.pdf</a>&nbsp;<br />BIOKDD 2002: Recent Advances in Data Mining for&nbsp;<br />Bioinformatics:&nbsp;<a href="http://www.acm.org/sigs/sigkdd/explorations/issue4-2/zaki.pdf">http://www.acm.org/sigs/sigkdd/explorations/issue4-2/zaki.pdf</a></p><p><strong>Bioinformatics and Medical Informatics:</strong>&nbsp;<br /><br />Tools for Mining and Applying Genetic Information in Patient Care:<a href="http://www.biomedtechalliance.org/pdfs/03_03_05/03_03_05.pdf">http://www.biomedtechalliance.org/pdfs/03_03_05/03_03_05.pdf</a></p><p>DATA MINING OF MICROARRAY DATABASES FOR HUMAN LUNG CANCER:&nbsp;<a href="http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.106.385&amp;rep=rep1&amp;type=pdf">http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.106.385&amp;rep=rep1&amp;type=pdf</a></p><p>Towards knowledge-based gene expression data mining:&nbsp;<a href="http://www.ailab.si/blaz/papers/2007-JBI-BellazziZupan.pdf">http://www.ailab.si/blaz/papers/2007-JBI-BellazziZupan.pdf</a></p><p>DRAFT Accepted for publication in 'Data Mining in Bioinformatics'<br />Jason Wang, Mohammed Zaki, Hannu Toivonen, and Dennis Shasha (Eds.), Springer:<a href="http://www.cs.helsinki.fi/u/htoivone/pubs/gene_mapping_by_pattern_discovery.pdf">http://www.cs.helsinki.fi/u/htoivone/pubs/gene_mapping_by_pattern_discovery.pdf</a></p><p>Data Mining and Text Mining for Bioinformatics: Proceedings of the European Workshop:&nbsp;<a href="http://www.rok.informatik.hu-berlin.de/wbi/research/publications/2003/proceedings_ws_mining.pdf">http://www.rok.informatik.hu-berlin.de/wbi/research/publications/2003/proceedings_ws_mining.pdf</a></p><p><strong>Biological Network Analysis:<br /></strong><br />Graph Mining in Bioinformatics:&nbsp;<a href="http://agbs.kyb.tuebingen.mpg.de/wikis/bg/BNA-5.pdf">http://agbs.kyb.tuebingen.mpg.de/wikis/bg/BNA-5.pdf</a>.</p><p>Text mining in bioinformatics:&nbsp;<a href="http://agbs.kyb.tuebingen.mpg.de/wikis/bg/4.pdf">http://agbs.kyb.tuebingen.mpg.de/wikis/bg/4.pdf</a></p><p>Some datamining books that are available on google books:</p><p>Data mining and bioinformatics: first international workshop, VDMB 2006 By Mehmet M. Dalkilic</p><p>Data mining: concepts and techniques By Jiawei Han, Micheline Kamber</p>]]></description>
	<dc:creator>Jitendra Narayan</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/1295/five-points-for-bioinformatics-softwaretools</guid>
	<pubDate>Mon, 05 Aug 2013 04:12:32 -0500</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/1295/five-points-for-bioinformatics-softwaretools</link>
	<title><![CDATA[Five points for bioinformatics software/tools]]></title>
	<description><![CDATA[<p><span>In the bioinformatics sector we mostly spend time on computational analysis of huge amounts of data and try to make sense of it, biologically. But, most of the newbie bioinformaticians are faced with dilemma when they receive biological sequence data for the first time. They mostly found confusing over open source, user friendly GUI, and commercial bioinformatics software. Don&rsquo;t be surprise this is true and also not an easy task to decide, because analytical step is the most crucial part and believe to be the biggest bottleneck in publishing paper in high impact journals. Through this blog I would like to address the pros and cons of both kind of software/tools and try to assist (Hmmm not really, It looks convince) you to make decision on your software selections.</span></p><p><span><img src="http://bioinformaticsonline.com/mod/photo/five.jpg" alt="image" style="border: 0px;"></span></p><p><span>The most common newbie questions are:</span><span></span></p><p><span>Should I try to use these free open source programs? &nbsp;Why are we not trying GUI software for computational analysis? Should I use commercial bioinformatics programs/software?&rdquo;</span><span><br /></span><span><br />1. Let&rsquo;s be open</span><span></span></p><p><span>We generally think free and cheap are useless. But this concept is not applicable when we discuss open source software. Mostly, the bioinformatics software is developed by highly competitive biological programmers who believe in open sharing of knowledge. They come under Open Bioinformatics Foundation or O|B|F which is a non-profit, volunteer run organization focused on supporting open source programming in bioinformatics. The best part about open source tools/software is that they&rsquo;re free to download the source code and read exactly what the program does. If you are so inclined, you can view all of the parts of the program and see the logical flow of the pipeline. In addition, open source makes an excellent learning tool for any beginning bioinformatician. Moreover, you can modify existing open source programs to deal with cutting-edge problems or to customize your pipeline.</span><span>&nbsp;</span><span>Apart from your computational and analysis work, most of the reviewer also prefers the open source based results so that they can validate the results if validation required.</span></p><p><span>2. Code headache</span><span></span></p><p><span>As a bioinformatician you are supposed to know the basics of programming languages, and if you are not good at it, then please learn it as soon as possible because you are not a bio-analyst but biological programmers. The<span>&nbsp;</span>open source programs usually lack dedicated service and support teams (often because they were the product of an overworked doc/postdoc!) so you are responsible for troubleshooting your own errors most of the time.<span>&nbsp;</span>We commonly receive the HELP email to support and assist to setup the pipeline; you can also find this kind of request on any QA forum. I personally believe this coding horror brings the biggest downside of open-source programs; where you need some programming skills in order to implement the program in your pipeline. But, if you are not able to fix the pipeline and modify the open source code according to your requirements them you should re-think on your bioinformatician name tag!!!</span><span></span></p><p><span>3. Dive into the codes</span><span></span></p><p><span>Some of the biologist turn bioinformatician says &ldquo;if you can do the same thing with commercial software then why to get migraine with weird codes&rdquo;, well this statement looks to me that guys are keen to learn swimming but still don&rsquo;t like to get wet. If you are still using paid software and doing your work by customer support and clicking some of the well-designed GUI button then perhaps you are not interested in learning and trying new and challenging bioinformatics works. You are missing the basic flavour of bioinformatics. Let&rsquo;s dive into the coding world, I am sure your will enjoy it. I recommend your to swim freely in code&rsquo;s sea, and enjoy the journey; do not merely watch it from the outside. &nbsp;</span></p><p><span>4. Paid does not mean better</span><span></span></p><p><span>The bioinformatics company which are specializes in bioinformatics solutions develop well designed/packed, user friendly software by using a large number of specialised scientist, programmers and support staff. They also provide good services to accomplice your biological analysis work. This means that if you hit a &lsquo;snag&rsquo; with your data, help is likely only a phone call away! These companies price their products competitively against the cost of a dedicated bioinformatician. You may be able to afford the program, but not the additional staff! Additionally, most of the functionality that you need in your analysis is already coded into the program. Need to plot a graph? Just click this button right here. It is that easy.</span><span>&nbsp;</span><span>But, as a bioinformatician this is not generally well encouraged approach in biological analysis work, because the software is not available to everyone and your data can&rsquo;t be validated. Moreover, there is very less chances that anyone will repeat your work or love to do similar kind of research (because not all the labs in the world are rich like yours).</span></p><p><span>5. Take a caution<br /><br />In biological analysis work, in which you deal GB/TB of data are having maximum chances of getting errors, so please be careful and always cross check your data before coming to any conclusion. Even an error in two line code can alter your entire analysis and display weird results. Some of the scientist blindly believes on commercial software, which is entirely wrong. Using proprietary tools does not absolve you of the need to actually read and research the type of analysis that you are doing. This is particularly true in the case of genome assembly and annotation.</span></p><p><span><br />At the end, I would like to tell only one think that open source solutions allows you to do more cutting edge analysis than the commercial tools. So let&rsquo;s go for it.</span></p><p>Disclaimer:</p><p>This is my personal view. I have nothing to do with any company or open source community.&nbsp;The views expressed on these pages are mine alone and not those of my current/past employers. I do reserve the right to remove comments left by spammers or off-topic comments.</p>]]></description>
	<dc:creator>Jitendra Narayan</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/1469/prime-minister%E2%80%99s-100k-genome-project</guid>
	<pubDate>Thu, 08 Aug 2013 09:40:39 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/1469/prime-minister%E2%80%99s-100k-genome-project</link>
	<title><![CDATA[Prime Minister’s 100k Genome Project]]></title>
	<description><![CDATA[<p>Genomics Ebgland is destined to sequence 100,000 patients over the next five year in England.&nbsp; A landmark project by british government.</p><p>Genomics England will play a key role in building on the UK&rsquo;s long track record as leader in medical science advances to push the boundaries by unlocking the power of DNA data. The UK will become the first ever country to introduce this technology in its mainstream health system &ndash; leading the global race for better tests, better drugs and above all better, more personalised care.</p><p>http://www.genomicsengland.co.uk/100k-genome-project/</p>]]></description>
	<dc:creator>Jitendra Narayan</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/view/2021</guid>
	<pubDate>Mon, 12 Aug 2013 09:27:57 -0500</pubDate>
	<link>https://bioinformaticsonline.com/view/2021</link>
	<title><![CDATA[What are the difference between BioRuby and BioGem?]]></title>
	<description><![CDATA[<p>I came across two diferent but matching term BioRuby and BioGem. What are the difference between these two term? If both are using same Ruby language for development then why did they develope two different biological packages.</p>]]></description>
	<dc:creator>Neel</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/videolist/watch/4090/computational-biology-in-the-21st-century-making-sense-out-of-massive-data</guid>
	<pubDate>Thu, 29 Aug 2013 08:32:26 -0500</pubDate>
	<link>https://bioinformaticsonline.com/videolist/watch/4090/computational-biology-in-the-21st-century-making-sense-out-of-massive-data</link>
	<title><![CDATA[Computational Biology in the 21st Century: Making Sense out of Massive Data]]></title>
	<description><![CDATA[<iframe width="" height="" src="https://www.youtube-nocookie.com/embed/I99UiA_vaJQ" frameborder="0" allowfullscreen></iframe>Computational Biology in the 21st Century: Making Sense out of Massive Data    
    
Air date:  Wednesday, February 01, 2012, 3:00:00 PM
Category:  Wednesday Afternoon Lectures  
 
Description:  The last two decades have seen an exponential increase in genomic and biomedical data, which will soon outstrip advances in computing power to perform current methods of analysis. Extracting new science from these massive datasets will require not only faster computers; it will require smarter algorithms. We show how ideas from cutting-edge algorithms, including spectral graph theory and modern data structures, can be used to attack challenges in sequencing, medical genomics and biological networks. 

The NIH Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide. 

Author:  Dr. Bonnie Berger  
Runtime:  00:58:06  
Permanent link:  http://videocast.nih.gov/launch.asp?17563]]></description>
	
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/2334/binc-bioinformatics-national-certification-website-address</guid>
	<pubDate>Wed, 14 Aug 2013 09:40:22 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/2334/binc-bioinformatics-national-certification-website-address</link>
	<title><![CDATA[BINC (BioInformatics National Certification) Website address]]></title>
	<description><![CDATA[<p><span>BINC (BioInformatics National Certification) is an initiative of Department of Biotechnology(DBT), Government Of India in coordination with Bioinformatics Center, University of Pune. The objective of the examination is to recognize trained manpower in the area of Bioinformatics. Currently, various Indian universities, Government and private institutions are involved in imparting courses in Bioinformatics in India.</span></p>
<p>Foreign nationals intending to have certification are eligible to appear for BINC examination.<br>Minimum qualification includes a degree from a recognized university/institute in the areas listed in FAQ.<br>Formal training in the area of Bioinformatics is not a prerequisite.<br>Note that the foreign students will only be certified by DBT and are not eligible for the cash award as well as junior research fellowship.</p><p>Address of the bookmark: <a href="http://binc.scisjnu.ernet.in/" rel="nofollow">http://binc.scisjnu.ernet.in/</a></p>]]></description>
	<dc:creator>Kamalakshi Mukherjee</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/2457/rdataminingcom-r-and-data-mining</guid>
	<pubDate>Thu, 15 Aug 2013 18:37:23 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/2457/rdataminingcom-r-and-data-mining</link>
	<title><![CDATA[Rdatamining.com : R and Data Mining]]></title>
	<description><![CDATA[<p>This website presents examples, documents and resources on data mining with R. <br>Documents on using R for data mining are available to download for non-commercial personal use, including&nbsp;R Reference card for Data Mining, R and Data Mining: Examples and Case Studies and Time Series Analysis and Mining with R.</p><p>Address of the bookmark: <a href="http://www.rdatamining.com/" rel="nofollow">http://www.rdatamining.com/</a></p>]]></description>
	<dc:creator>Poonam Mahapatra</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/2646/bioinformatics-infrastructure-facility-bif-gargi-college-university-of-delhi-traineeship</guid>
  <pubDate>Mon, 19 Aug 2013 18:43:03 -0500</pubDate>
  <link></link>
  <title><![CDATA[Bioinformatics Infrastructure Facility (BIF), Gargi College, University of Delhi @ Traineeship]]></title>
  <description><![CDATA[
<p>Gargi College was established in the year 1967 and is a leading South Campus college of the University of Delhi. It is a college for women and offers education in Arts and Humanities, Commerce, Science and Education.</p>

<p>Gargi believes in its mission statement that every student who passes through the portals of the college emerges as a wholly developed individual symbolizing the spirit of enterprise and inquiry that characterizes Gargi.</p>

<p>Bioinformatics Infrastructure Facility (BIF), Gargi College, University of Delhi invites candidates for filling up the following purely temporary positions sponsored by DBT, New Delhi.</p>

<p>1. Name of the post: Traineeship<br />Essential Qualification: Post Graduate degree in Bioinformatics or any other branch of Life Sciences preferably with dissertation in Bioinformatics.<br />Desirable Qualification: Prior knowledge of programming languages such as C, VB, SQL etc. and software/database development.</p>

<p>2. Name of the post: Research Associate<br />Essential Qualification: PhD in Bioinformatics/Biological Sciences/Computer Science or allied sciences with proven experience in bioinformatics.</p>

<p>3. Name of the post: Studentship<br />Essential Qualifications: Final year Post Graduate students pursuing a degree in Bioinformatics or any branch of Life Science with knowledge of bioinformatics.</p>

<p>How to apply:<br />Interested candidates are required to appear for the walk in interview on 29th Aug, 2013 at 10.00 AM in Principal’s Office, Gargi College, Sirifort Road, N. Delhi-110049, with their CVs, original documents and a set of Photostat copies of all original documents.</p>

<p>http://www.du.ac.in/fileadmin/DU/students/Pdf/du/advt/2013/16082013_Gargi_RAplus2_Advt.pdf</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/42672/introduction-to-bioinformatics-and-computational-biology</guid>
	<pubDate>Mon, 25 Jan 2021 01:32:30 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/42672/introduction-to-bioinformatics-and-computational-biology</link>
	<title><![CDATA[Introduction to Bioinformatics and Computational Biology]]></title>
	<description><![CDATA[<p><span>This is the course material for STAT115/215 BIO/BST282 at Harvard University.</span></p>
<p>Xiaole Shirley Liu (lead instructor)<br>Joshua Starmer<br>Martin Hemberg<br>Ting Wang<br>Feng Yue</p>
<p>Ming Tang<br>Yang Liu<br>Jack Kang<br>Scarlett Ge<br>Jiazhen Rong<br>Phillip Nicol<br>Maartin De Vries</p>
<p>We thank many colleagues in the community, who helped Dr.&nbsp;Liu in prepare the STAT115/215 BIO/BST282 course over the years.&nbsp;</p><p>Address of the bookmark: <a href="https://liulab-dfci.github.io/bioinfo-combio/" rel="nofollow">https://liulab-dfci.github.io/bioinfo-combio/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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