BOL: Related items

HINGE: Long-Read Assembly Achieves Optimal Repeat Resolution

Jit — Wed, 07 Feb 2018 09:40:22 -0600

Software accompanying "HINGE: Long-Read Assembly Achieves Optimal Repeat Resolution"

Preprint: http://biorxiv.org/content/early/2016/08/01/062117
Paper: http://genome.cshlp.org/content/27/5/747.full
An ipython notebook to reproduce results in the paper can be found in this repository.

HINGE is an OLC(Overlap-Layout-Consensus) assembler. The idea of the pipeline is shown below.

Address of the bookmark: https://github.com/HingeAssembler/HINGE

Bioinformatics lectures !

Jit — Wed, 29 Nov 2017 05:39:54 -0600

Computational Biology is a huge field of study, that touches upon many distinct algorithmic and biological areas of study. What we are able to cover in this course will depend, in part, on the pace at which we move, which I will attempt to adjust as appropriate. However, here is a tentative list of topics I hope to cover this semester (not necessarily in order).

Optimal sequence alignment (global, local, and glocal alignment &mdash with constant & affine gap penalties
Algorithms and data structures for efficient text indexing and exact search
Heuristics for read alignment and mapping &mdash mapping DNA-seq and RNA-seq reads
Genome assembly &mdash k-mers, De Brujin graph construction and representation, long-read technology and read-overlap graph assembly
Motif finding via Gibbs sampling
Gene finding &mdash statistical models for ab initio and evidence-guided prediction of genes
RNA-seq and transcriptomics &mdash transcript assembly, abundance estimation and differential expression testing
Phylogenetics &mdash The small and large phylogeny problem; parsimony, maximum likelihood and Bayesian methods

Address of the bookmark: https://rob-p.github.io/CSE549F16/lectures/

EvidentialGene: tr2aacds, mRNA Transcript Assembly Software

Rahul Nayak — Tue, 08 May 2018 04:39:39 -0500

EvidentialGene is a genome informatics project, "Evidence Directed Gene Construction for Eukaryotes", to construct high quality, accurate gene sets for animals and plants, developed by Don Gilbert at Indiana University, see
http://arthropods.eugenes.org/EvidentialGene/

Construction refers to the combination of classical gene prediction, and more recent gene assembly (de-novo and genome-assisted) methods. The basic Evigene methods involve using available best-of-breed gene prediction and assembly software, combining all evidence for genes, from expressed sequences, genome assembly sequences, related species protein sequences, and any other, to annotate and score gene constructions. Over-produced constructions are classified by gene evidence for best qualities per "locus", including genome-aligned and gene-transcript aligned (genome-free) locus identification. All software developed for EvidentialGene is publicly available. See project wiki/blog for notes.

Download

http://arthropods.eugenes.org/EvidentialGene/trassembly.html

https://sourceforge.net/p/evidentialgene/blog/

Address of the bookmark: http://arthropods.eugenes.org/EvidentialGene/trassembly.html

Bioinformatics postdoctoral position at inStem

Tue, 13 Feb 2018 03:18:54 -0600

One postdoctoral position is available in the area of Bioinformatics. This position is available through a highly collaborative project involving multiple labs.

The primary focus here would be to analyse and integrate high throughput data from various aspects of translation regulation including non-coding RNAs, mRNAs and modification of ribosomal RNA. We request the interested candidates to approach either

Dasaradhi Palakodeti (dasaradhip@instem.res.in)
Or
Ravi Muddashetty (ravism@instem.res.in)

Bioinformatics postdoctoral position at CSIR - Institute of Himalayan Bioresource Technology, Palampur (H.P.)

Thu, 05 Apr 2018 06:57:17 -0500

Walk-in-Interview is scheduled to be held on the date as mentioned below for selection of Suitable candidates in the following areas under the DBT sponsored projecT on purely temporary basis for the duration of the project(s) or till completion of projects whichever is earlier:

Project Title:
"Exploration of RBP-RNA interactions to reveal the post-transcriptional regulatory impact, and development of related tools and resource server".

Position: Research Associate (1 position)
Age : 35 years as on 02.05.2018
Salary : Rs.36,000/- P.M. + H.R.A.

as per the funds provisions in the respective projects.

Eligibility Criteria :
Essential Qualifications: Ph.D. in any area of Bioinformatics/ Computational Biology/ Life Sciences.
Desirable: Candidate having experience in Bioinformatics will be preferred.

Essential Qualifications: M.Tech. in Bioinformatics/ Computation Biology/ Computer Science or any related area with 3 years of research experience.

Selection Procedure : Walk In Interview

Date : 02 May, 2018
Time : 9:30 A.M.
Venue : CSIR-IHBT Palampur (H.P.)

For more info refer to following doc:

http://ihbt.res.in/components/com_chronoforms5/chronoforms/uploads/Recruitment/20180404125233_AdvtNo11_2018.pdf

Bioinformatics Project Assistant Level II position at CSIR - Institute of Himalayan Bioresource Technology, Palampur (H.P.)

Thu, 17 May 2018 01:53:17 -0500

Walk-in-Interview is scheduled to be held on the date as mentioned below for selection of Suitable candidates in the following areas under the DBT sponsored project on purely temporary basis for the duration of the project(s) or till completion of projects whichever is earlier:

Project Title:
"Exploration of RBP-RNA interactions to reveal the post-transcriptional regulatory impact, and development of related tools and resource server".

Position: Project Assistant Level II (1 position)
Age : 28 years as on 14.06.2018
Salary : Rs.25,000/- P.M.

as per the funds provisions in the respective projects.

Eligibility Criteria :
Essential Qualifications: M.Sc. in Bioinformatics / Computational Biology or any area of Bioinformatics with 55% marks.

Essential Qualifications: M.Sc. in any area of Life Sciences with 55% marks with Diploma in any area of Bloinformatics.

Essential Qualifications: B.Tech. / M.Tech. in Bioinformatics / Computer Science with 55% marks.

Selection Procedure : Walk In Interview

Date : 14 June, 2018
Time : 9:30 A.M.
Venue : CSIR-IHBT Palampur (H.P.)

For more info refer to following doc:

http://ihbt.res.in/components/com_chronoforms5/chronoforms/uploads/Recruitment/20180516114701_Advt15_2018.pdf

Applied Statistics for Bioinformatics using R

Neel — Thu, 30 Aug 2018 03:45:39 -0500

The purpose of this book is to give an introduction into statistics in order to solve some problems of bioinformatics. Statistics provides procedures to explore and visualize data as well as to test biological hypotheses. The book intends to be introductory in explaining and programming elementary statistical concepts, thereby bridging the gap between high school levels and the specialized statistical literature

SPADes team announce new version SPADes v3.15

BioStar — Fri, 15 Jan 2021 10:24:27 -0600

New SPAdes 3.15.0.0. announced by the SPADes team This release includes such new features as:
- CoronaSPAdes pipeline for the assembly of transcriptomic and metatranscriptomic data of full-length coronaviridae genomes;
- Meta-Viral and RNA-Viral pipelines for metagenomic and metatranscriptomic data defining viral genomes;
-New trusted contiguous use algorithm;
-Switched to the memory allocator mimalloc;
- PlasmidSPAdes and bgcSPAdes are now provided as an input assembly graph;
- Important improvements and corrections to the metaplasmid pipeline;
- Multiple performance improvements in procedures for simplification and repeat resolving.
Please, consider updating.

Check out more at https://cab.spbu.ru/software/spades/

BETSY: A new backward-chaining expert system for automated development of pipelines in Bioinformatics

Jit — Mon, 17 Dec 2018 18:46:51 -0600

The BETSY provides a command-line interface and available at https://github.com/jefftc/changlab. A user first searches in the knowledge base for desired output and then BETSY develops an initial workflow to produce that data which is later examined by the user. The user can optimize the parameters, the algorithm to preprocess the data, and normalize it depending on the task.

Currently, BETSY consists of modules required for the microarray and next-generation sequencing data [4] such as expression analysis, classification, peak calling, and visualization.

Address of the bookmark: https://github.com/jefftc/changlab

Tenure Track position in Bioinformatics at Institute of Neurobiology, UNAM, Querétaro, México

Mon, 10 Jun 2019 00:48:54 -0500

The Institute of Neurobiology UNAM (www.inb.unam.mx) offers a tenure-track position at the level of Assistant Professor (Investigador Asociado C) to develop an original research program in Bioinformatics with applications to neuroscience and to establish multidisciplinary collaboration with other members of the Institute. Applicants are expected to have a doctorate degree, postdoctoral experience related to bioinformatics or genome biology, and a strong track record of peer-reviewed publications. No previous experience in neuroscience is required.

Interested applicants must submit CV and addresses of three references to ataulfo@unam.mx.

Tenure Track position in Genomic Sciences

Laboratorio Internacional de Investigación sobre el Genoma Humano, UNAM Juriquilla, Querétaro, México

The International Laboratory for Human Genome Research, LIIGH-UNAM (www.liigh.unam.mx) offers a tenure-track position at the level of Assistant Professor (Investigador Asociado C) to perform research, teaching and formation of human resources in the area of: “Genomics of Mendelian Diseases”

Applicants are expected to have a doctorate degree, postdoctoral experience related to the above mentioned area and a strong track record of peer-reviewed publications. Interested applicants must submit CV, email addresses of three references, and a three-page project to Dr. Rafael Palacios, Coordinator of LIIGH-UNAM (palacios@liigh.unam.mx) before June 21, 2019 ………………………………………………………………

Tenure Track position in Genomic Sciences

Laboratorio Internacional de Investigación sobre el Genoma Humano, UNAM Juriquilla, Querétaro, México

Applicants are expected to have a doctorate degree, postdoctoral experience related to the above mentioned area and a strong track record of peer-reviewed publications. Interested applicants must submit CV, email addresses of three references, and a three-page statement of research interests to Dr. Rafael Palacios, Coordinator of LIIGH-UNAM (palacios@liigh.unam.mx) before June 21, 2019