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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/26303?offset=50</link>
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	<description><![CDATA[]]></description>
	
	<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/34328/dfast-a-flexible-prokaryotic-genome-annotation-pipeline-for-faster-genome-publication</guid>
	<pubDate>Tue, 14 Nov 2017 10:26:16 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/34328/dfast-a-flexible-prokaryotic-genome-annotation-pipeline-for-faster-genome-publication</link>
	<title><![CDATA[DFAST: a flexible prokaryotic genome annotation pipeline for faster genome publication]]></title>
	<description><![CDATA[<p>We developed a prokaryotic genome annotation pipeline, DFAST, that also supports genome submission to public sequence databases. DFAST was originally started as an on-line annotation server, and to date, over 7,000 jobs have been processed since its first launch in 2016. Here, we present a newly implemented background annotation engine for DFAST, which is also available as a standalone command-line program. The new engine can annotate a typical-sized bacterial genome within 10 minutes, with rich information such as pseudogenes, translation exceptions, and orthologous gene assignment between given reference genomes. In addition, the modular framework of DFAST allows users to customize the annotation workflow easily and will also facilitate extensions for new functions and incorporation of new tools in the future.</p>
<div>Availability and Implementation</div>
<p>The software is implemented in Python 3 and runs in both Python 2.7 and 3.4&ndash; on Macintosh and Linux systems. It is freely available at&nbsp;<a href="https://github.com/nigyta/dfast_core/" target="">https://github.com/nigyta/dfast_core/</a>&nbsp;under the GPLv3 license with external binaries bundled in the software distribution. An on-line version is also available at&nbsp;<a href="https://dfast.nig.ac.jp/" target="">https://dfast.nig.ac.jp/</a>.</p><p>Address of the bookmark: <a href="https://dfast.nig.ac.jp/" rel="nofollow">https://dfast.nig.ac.jp/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/27090/canu-assembling-large-genomes-with-single-molecule-sequencing-and-locality-sensitive-hashing</guid>
	<pubDate>Tue, 26 Apr 2016 11:38:10 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/27090/canu-assembling-large-genomes-with-single-molecule-sequencing-and-locality-sensitive-hashing</link>
	<title><![CDATA[CANU: Assembling Large Genomes with Single-Molecule Sequencing and Locality Sensitive Hashing.]]></title>
	<description><![CDATA[<p>Canu is a fork of the&nbsp;<a href="http://wgs-assembler.sourceforge.net/wiki/index.php?title=Main_Page" title="Celera Assembler">Celera Assembler</a>&nbsp;designed for high-noise single-molecule sequencing (such as the PacBio RSII or Oxford Nanopore MinION). The software is currently alpha level, feel free to use and report issues encountered.</p>
<p>Canu is a hierachical assembly pipeline which runs in four steps:</p>
<ul>
<li>Detect overlaps in high-noise sequences using&nbsp;<a href="https://github.com/marbl/MHAP" title="MHAP">MHAP</a></li>
<li>Generate corrected sequence consensus</li>
<li>Trim corrected sequences</li>
<li>Assemble trimmed corrected sequences</li>
</ul>
<p>Read the&nbsp;<a href="http://canu.readthedocs.org/" title="docs">documentation</a></p>
<p>New release https://github.com/marbl/canu/releases</p><p>Address of the bookmark: <a href="https://github.com/marbl/canu" rel="nofollow">https://github.com/marbl/canu</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/28999/redundans</guid>
	<pubDate>Thu, 01 Sep 2016 08:28:11 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/28999/redundans</link>
	<title><![CDATA[Redundans]]></title>
	<description><![CDATA[<p>Redundans pipeline assists&nbsp;<span>an assembly of heterozygous genomes</span>.<br>Program takes as input&nbsp;<span>assembled contigs</span>,&nbsp;<span>paired-end and/or mate pairs sequencing libraries</span>&nbsp;and returns&nbsp;<span>scaffolded homozygous genome assembly</span>, that should be&nbsp;<span>less fragmented</span>&nbsp;and with total&nbsp;<span>size smaller</span>&nbsp;than the input contigs. In addition, Redundans will automatically&nbsp;<span>close the gaps</span>&nbsp;resulting from genome assembly or scaffolding&nbsp;<a href="https://github.com/Gabaldonlab/redundans/blob/master/test#redundans-pipeline">more details</a>.</p>
<p>The pipeline consists of three steps/modules:</p>
<ul>
<li><span>redundancy reduction</span>: detection and selectively removal of redundant contigs from an initial&nbsp;<em>de novo</em>&nbsp;assembly</li>
<li><span>scaffolding</span>: joining of genome fragments using paired-end and/or mate-pairs reads</li>
<li><span>gap closing</span></li>
</ul>
<p>Redundans is:</p>
<ul>
<li><span>fast</span>&nbsp;&amp;&nbsp;<span>lightweight</span>, multi-core support and memory-optimised, so it can be run even on the laptop for small-to-medium size genomes</li>
<li><span>flexible</span>&nbsp;toward many sequencing technologies (Illumina, 454 or Sanger) and library types (paired-end, mate pairs, fosmids)</li>
<li><span>modular</span>: every step can be ommited or replaced by another tools</li>
</ul><p>Address of the bookmark: <a href="https://github.com/Gabaldonlab/redundans" rel="nofollow">https://github.com/Gabaldonlab/redundans</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/30130/scaffmatch</guid>
	<pubDate>Tue, 13 Dec 2016 10:23:56 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/30130/scaffmatch</link>
	<title><![CDATA[ScaffMatch]]></title>
	<description><![CDATA[<p>caffMatch is a novel scaffolding tool based on Maximum-Weight Matching able to produce high-quality scaffolds from NGS data (reads and contigs). The tool is written in Python 2.7. It also includes a bash script wrapper that calls aligner in case one needs to first map reads to contigs (instead of providing .sam files).</p>
<p>The arguments accepted by ScaffMatch are:</p>
<p>&nbsp; -w) Working directory -- this is the directory where ScaffMatch files are stored. These are .sam files produced after mapping reads to contigs and the resulting scaffolds file `scaffolds.fa` fasta file;</p>
<p>&nbsp; -c) Contig fasta file;</p>
<p>&nbsp; -m) Command line argument with no options. It is used when .sam files are used instead of reads .fastq files. Do not use this option if you provide reads files;</p>
<p>&nbsp; -1) (Comma separated list of) either .fastq or .sam file(s) corresponding to the first read of the read pair;</p>
<p>&nbsp; -2) (Comma separated list of) either .fastq or .sam file(s) corresponding to the second read of the read pair;</p>
<p>&nbsp; -i) (Comma separated list of) insert size(s) of the library(-ies);</p>
<p>&nbsp; -s) (Comma separated list of) library(-ies) standard deviation(s) of insert size(s);</p>
<p>&nbsp; -t) Bundle threshold. Pairs of contigs supported by number of read pairs less than the value of this argument are discarded. Optional argument, by default it is equal to 5;</p>
<p>&nbsp; -g) Matching heuristics: use `max_weight` for Maximum Weight Matching heuristics with the Insertion step, use `backbone` for Maximum Weight Matching heuristics without the Insertion step, use `greedy` for Greedy Matching heuristics;</p>
<p>&nbsp; -l) Log file - where to store the logs. Optional argument. By default, stdout is used.</p><p>Address of the bookmark: <a href="http://alan.cs.gsu.edu/NGS/?q=content/scaffmatch" rel="nofollow">http://alan.cs.gsu.edu/NGS/?q=content/scaffmatch</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/31353/concoct-clustering-contigs-with-coverage-and-composition</guid>
	<pubDate>Mon, 06 Mar 2017 04:08:16 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/31353/concoct-clustering-contigs-with-coverage-and-composition</link>
	<title><![CDATA[CONCOCT: Clustering cONtigs with COverage and ComposiTion]]></title>
	<description><![CDATA[<p>A program for unsupervised binning of metagenomic contigs by using nucleotide composition, coverage data in multiple samples and linkage data from paired end reads.</p>
<p>Warning! This software is to be considered under development. Functionality and the user interface may still change significantly from one version to another. If you want to use this software, please stay up to date with the list of known issues:<a href="https://github.com/BinPro/CONCOCT/issues">https://github.com/BinPro/CONCOCT/issues</a></p><p>Address of the bookmark: <a href="https://github.com/BinPro/CONCOCT" rel="nofollow">https://github.com/BinPro/CONCOCT</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/36592/lachesis-genome-assembly-with-hi-c-based-contact-probability-maps-lachesis</guid>
	<pubDate>Mon, 14 May 2018 04:26:30 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/36592/lachesis-genome-assembly-with-hi-c-based-contact-probability-maps-lachesis</link>
	<title><![CDATA[LACHESIS: Genome Assembly with Hi-C-based Contact Probability Maps (LACHESIS)]]></title>
	<description><![CDATA[<p>LACHESIS is method that exploits contact probability map data (e.g. from Hi-C) for chromosome-scale&nbsp;<em>de novo</em>&nbsp;genome assembly.</p>
<p>Further information about LACHESIS, including source code, documentation and a user's guide are available at:&nbsp;<a href="http://shendurelab.github.io/LACHESIS/">http://shendurelab.github.io/LACHESIS</a>.</p>
<p>Manuscript describing LACHESIS was published as: Burton JN#, Adey A, Patwardhan RP, Qiu R, Kitzman JO, Shendure J#.&nbsp;<em>Chromosome-scale scaffolding of de novo genome assemblies based on chromatin interactions.</em>&nbsp;Nature Biotechnology 2013 Dec;31(12):1119-25. doi:&nbsp;<a href="http://dx.doi.org/10.1038/nbt.2727">10.1038/nbt.272</a>. PubMed PMID:&nbsp;<a href="http://www.ncbi.nlm.nih.gov/pubmed/24185095">24185095</a>.</p>
<p>&nbsp;</p>
<p>http://shendurelab.github.io/LACHESIS/</p><p>Address of the bookmark: <a href="http://shendurelab.github.io/LACHESIS/" rel="nofollow">http://shendurelab.github.io/LACHESIS/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/4655/mathivanan-lab</guid>
  <pubDate>Fri, 20 Sep 2013 13:09:38 -0500</pubDate>
  <link></link>
  <title><![CDATA[Mathivanan Lab]]></title>
  <description><![CDATA[
<p>The major research interests are in exploring the role of extracellular matrix components (soluble secreted proteins and membrane vesicles) in cancer and intercellular communication. The lab integrates proteomic, genomic and bioinformatics methodologies to explore cancer cells. </p>

<p>More at http://www.mathivananlab.org/index.html</p>

<p>http://scholar.google.com/citations?user=U6PyEdYAAAAJ&amp;hl=en</p>
]]></description>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/19090/deeptools</guid>
	<pubDate>Sat, 08 Nov 2014 15:02:08 -0600</pubDate>
	<link>https://bioinformaticsonline.com/news/view/19090/deeptools</link>
	<title><![CDATA[deepTools]]></title>
	<description><![CDATA[<p>deepTools addresses the challenge of handling the large amounts of data that are now routinely generated from DNA sequencing centers. To do so, deepTools contains useful modules to process the mapped reads data to create coverage files in standard bedGraph and bigWig file formats. By doing so, deepTools allows the creation of normalized coverage files or the comparison between two files (for example, treatment and control). Finally, using such normalized and standardized files, multiple visualizations can be created to identify enrichments with functional annotations of the genome.<br /><br />Publicaton: http://nar.oxfordjournals.org/content/early/2014/05/05/nar.gku365.full<br /><br />Source Code and Wiki: https://github.com/fidelram/deepTools/wiki<br /><br />Galaxy Tool Shed repository: http://toolshed.g2.bx.psu.edu/view/bgruening/deeptools<br /><br />and example Galaxy workflows: http://toolshed.g2.bx.psu.edu/view/bgruening/deeptools_workflows</p>]]></description>
	<dc:creator>Martin Jones</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/19631/rosalind-bioinformatics-problems</guid>
	<pubDate>Thu, 18 Dec 2014 10:32:48 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/19631/rosalind-bioinformatics-problems</link>
	<title><![CDATA[Rosalind Bioinformatics problems !!!]]></title>
	<description><![CDATA[<p>Rosalind is a platform for learning bioinformatics and programming through problem solving. <a href="http://rosalind.info/problems/list-view/">Take a tour</a> to get the hang of how Rosalind works.</p>
<p>http://rosalind.info/problems/list-view/</p><p>Address of the bookmark: <a href="http://rosalind.info/problems/list-view/" rel="nofollow">http://rosalind.info/problems/list-view/</a></p>]]></description>
	<dc:creator>Abhi</dc:creator>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/22410/nicolas-corradi-lab</guid>
  <pubDate>Tue, 26 May 2015 16:19:02 -0500</pubDate>
  <link></link>
  <title><![CDATA[Nicolas Corradi Lab]]></title>
  <description><![CDATA[
<p>The goal of our research is to better understand the biology of microbial organisms of significant ecological, veterinary and medical importance.<br />To achieve this goal, our team combines the power of next generation DNA sequencing and  bioinformatics with molecular biology and experimental procedures.</p>

<p>Main research topics:<br />- Comparative and Population Genomics of Plant Symbionts<br />- Parasite Genome Evolution<br />- Experimental Evolution of Microbial Symbionts and Parasites<br />- Phylogenomics of Early Branching Fungi</p>

<p>More at http://corradilab.weebly.com/</p>
]]></description>
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