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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/2631?offset=380</link>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/34711/1mb-long-dna-with-nanopore-technology</guid>
	<pubDate>Tue, 19 Dec 2017 18:49:28 -0600</pubDate>
	<link>https://bioinformaticsonline.com/news/view/34711/1mb-long-dna-with-nanopore-technology</link>
	<title><![CDATA[1mb long DNA with Nanopore technology]]></title>
	<description><![CDATA[<p>The first continuous DNA read of more than a million bases (&gt;1Mb) has been achieved, using Oxford Nanopore sequencing technology. Congratulations to Martin Smith and collaborators! Read more: http://bit.ly/2j5TNCO</p>]]></description>
	<dc:creator>Jit</dc:creator>
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<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/17500/joao-pedro-de-magalhaes-lab</guid>
  <pubDate>Fri, 26 Sep 2014 19:08:34 -0500</pubDate>
  <link></link>
  <title><![CDATA[Joao Pedro de Magalhaes Lab]]></title>
  <description><![CDATA[
<p>Ageing has a profound impact on human society and modern medicine, yet it remains a major puzzle of biology. The goal of my work is to help understand the genetic, cellular, and molecular mechanisms of ageing. In the long term, I would like my work to help ameliorate age-related diseases and preserve health. No other biomedical field has so much potential to improve human health as research on the basic mechanisms of ageing. Please see our lab website for further details about our work and publications. </p>

<p>Functional and Comparative Genomics</p>

<p>http://jp.senescence.info/<br />http://www.senescence.info/<br />http://www.liv.ac.uk/integrative-biology/staff/joao-de-magalhaes/</p>
]]></description>
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<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/36271/heap-a-highly-sensitive-and-accurate-snp-detection-tool-for-low-coverage-high-throughput-sequencing-data</guid>
	<pubDate>Thu, 19 Apr 2018 08:06:03 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/36271/heap-a-highly-sensitive-and-accurate-snp-detection-tool-for-low-coverage-high-throughput-sequencing-data</link>
	<title><![CDATA[Heap: a highly sensitive and accurate SNP detection tool for low-coverage high-throughput sequencing data]]></title>
	<description><![CDATA[<p><span>Heap, that enables robustly sensitive and accurate calling of SNPs, particularly with a low coverage NGS data, which must be aligned to the reference genome sequences in advance. To reduce false positive SNPs, Heap determines genotypes and calls SNPs at each site except for sites at the both end of reads or containing a minor allele supported by only one read. Performance comparison with existing tools showed that Heap achieved the highest F-scores with low coverage (7X) restriction-site associated DNA sequencing reads of sorghum and rice individuals. This will facilitate cost-effective GWAS and GP studies in this NGS era. Code and documentation of Heap are freely available from&nbsp;</span><a href="https://github.com/meiji-bioinf/heap">https://github.com/meiji-bioinf/heap</a><span>&nbsp;and our web site (</span><a href="http://bioinf.mind.meiji.ac.jp/lab/en/tools.html">http://bioinf.mind.meiji.ac.jp/lab/en/tools.html</a><span>).</span></p><p>Address of the bookmark: <a href="https://github.com/meiji-bioinf/heap" rel="nofollow">https://github.com/meiji-bioinf/heap</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/23628/postgraduate-research-associate-bioinformatics-computational-biology-reference-code-59</guid>
  <pubDate>Tue, 04 Aug 2015 20:32:39 -0500</pubDate>
  <link></link>
  <title><![CDATA[Postgraduate Research Associate Bioinformatics / Computational Biology (Reference code: 59)]]></title>
  <description><![CDATA[
<p>The Department of Biotechnology, group “Genome Bioinformatics” is currently seeking a Postgraduate Research Associate Bioinformatics / Computational Biology (Reference code: 59)</p>

<p>Extent of employment: 30 Hours per Week<br />Duration of employment: 1st of October 2015 to 30th of September 2019<br />Gross monthly salary and pay grade in terms of collective agreement for university staff (payable 14 times per year): B1, € 1.997,20</p>

<p>Responsibilities<br />The successful candidate (f/m) will pursue a Ph.D. project related to the interpretation of plant genome and transcriptome sequencing data from next-generation sequencing (NGS) platforms. In particular, the candidate will characterize the unexplored genome of quinoa, a crop plant of long-standing tradition in Latin America. We collaborate with research partners in Austria and abroad, and the candidate’s project will be of central importance in the context of this research network.</p>

<p>Required skills and qualifications<br />We are looking for a graduate student (f/m) with a Master’s degree in bioinformatics or in a related field, solid programming skills (e.g. developing sequence analysis tools), experience with the analysis of NGS data sets, understanding of lab methods and knowledge of genomics/transcriptomics. The group has successfully performed several projects using NGS technology. We have recently published the reference genome sequence of sugar beet (Dohm et al., Nature, 2014), a crop plant closely related to quinoa (same family, but different genus). Not yet published is a quinoa genome assembly that we have generated, and which will serve as the starting point of the candidate’s project. We are a multidisciplinary team and offer work in a lively and friendly atmosphere, and state-of-the-art computing infrastructure. We are looking forward to expanding our team by a dedicated and strongly motivated person with a distinct interest in the challenges of plant genomics.</p>

<p>Applications can be submitted until: 16th of August 2015</p>

<p>University of Natural Resources and Life Sciences Vienna seeks to increase the number of its female faculty and staff members. Therefore qualified women are strongly encouraged to apply. In case of equal qualification, female candidates will be given preference unless reasons specific to an individual male candidate tilt the balance in his favour.</p>

<p>Please send your job application (incl. letter of motivation, CV, summary of Master’s thesis and contact details for two referees) to Personnel department, University of Natural Resources and Life Sciences, 1190 Vienna, Peter-Jordan-Straße 70; E-Mail: kerstin.buchmueller@boku.ac.at. (Reference code: 59)</p>

<p>We regret that we cannot reimburse applicants travel and lodging expenses incurred as part of the selection and hiring process.</p>

<p>www.boku.ac.at</p>
]]></description>
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<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/36533/mecat-fast-mapping-error-correction-and-de-novo-assembly-for-single-molecule-sequencing-reads</guid>
	<pubDate>Fri, 11 May 2018 05:07:45 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/36533/mecat-fast-mapping-error-correction-and-de-novo-assembly-for-single-molecule-sequencing-reads</link>
	<title><![CDATA[MECAT: fast mapping, error correction, and de novo assembly for single-molecule sequencing reads]]></title>
	<description><![CDATA[<p>MECAT is an ultra-fast Mapping, Error Correction and de novo Assembly Tools for single molecula sequencing (SMRT) reads. MECAT employs novel alignment and error correction algorithms that are much more efficient than the state of art of aligners and error correction tools. MECAT can be used for effectively de novo assemblying large genomes. For example, on a 32-thread computer with 2.0 GHz CPU , MECAT takes 9.5 days to assemble a human genome based on 54x SMRT data, which is 40 times faster than the current&nbsp;<a href="http://cbcb.umd.edu/software/pbcr/mhap/">PBcR-Mhap pipeline</a>. MECAT performance were compared with&nbsp;<a href="http://cbcb.umd.edu/software/pbcr/mhap/">PBcR-Mhap pipeline</a>,&nbsp;<a href="https://github.com/PacificBiosciences/falcon">FALCON</a>&nbsp;and&nbsp;<a href="http://canu.readthedocs.io/en/latest/">Canu(v1.3)</a>&nbsp;in five real datasets. The quality of assembled contigs produced by MECAT is the same or better than that of the&nbsp;<a href="http://cbcb.umd.edu/software/pbcr/mhap/">PBcR-Mhap pipeline</a>&nbsp;and&nbsp;<a href="https://github.com/PacificBiosciences/falcon">FALCON</a>.&nbsp;</p>
<p>https://www.nature.com/articles/nmeth.4432</p><p>Address of the bookmark: <a href="https://github.com/xiaochuanle/MECAT" rel="nofollow">https://github.com/xiaochuanle/MECAT</a></p>]]></description>
	<dc:creator>Rahul Nayak</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/17898/ensembl-77-has-been-released</guid>
	<pubDate>Sun, 05 Oct 2014 16:38:58 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/17898/ensembl-77-has-been-released</link>
	<title><![CDATA[Ensembl 77 has been released!]]></title>
	<description><![CDATA[<h3>New updates in e!77 !!</h3><ul>
<li>Updated&nbsp;<a href="http://e77.ensembl.org/Homo_sapiens/Info/Index" title="Human species page">human</a>&nbsp;gene set (GENCODE 21)</li>
<li>Updated <a href="http://e77.ensembl.org/Rattus_norvegicus/Info/Index">rat</a> gene set&nbsp;including manual annotation from HAVANA</li>
<li>New species:&nbsp;<a href="http://e77.ensembl.org/Chlorocebus_sabaeus/Info/Index">Vervet-African green monkey</a></li>
<li>Imported Transcript Support Levels (TSLs) from UCSC&nbsp;for&nbsp;<a href="http://e77.ensembl.org/Homo_sapiens/Info/Index">human</a>&nbsp;and&nbsp;<a href="http://e77.ensembl.org/Mus_musculus/Info/Index">mouse</a></li>
<li>Imported <a href="http://appris.bioinfo.cnio.es/" target="_blank" title="APPRIS">APPRIS</a> flag for&nbsp;<a href="http://e77.ensembl.org/Homo_sapiens/Info/Index">human</a> and <a href="http://e77.ensembl.org/Mus_musculus/Info/Index">mouse</a></li>
<li>Updated <a href="http://e77.ensembl.org/Poecilia_formosa/Info/Index" title="Amazon molly">Amazon molly</a> gene set</li>
</ul><p>Find more at http://www.ensembl.info/blog/2014/10/02/ensembl-77-has-been-released/</p>]]></description>
	<dc:creator>Seema Singh</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/36806/manta-rapid-detection-of-structural-variants-and-indels-for-germline-and-cancer-sequencing-applications</guid>
	<pubDate>Mon, 28 May 2018 09:41:39 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/36806/manta-rapid-detection-of-structural-variants-and-indels-for-germline-and-cancer-sequencing-applications</link>
	<title><![CDATA[Manta: rapid detection of structural variants and indels for germline and cancer sequencing applications.]]></title>
	<description><![CDATA[Manta calls structural variants (SVs) and indels from mapped paired-end sequencing reads. It is optimized for analysis of germline variation in small sets of individuals and somatic variation in tumor/normal sample pairs. Manta discovers, assembles and scores large-scale SVs, medium-sized indels and large insertions within a single efficient workflow.<p>Address of the bookmark: <a href="https://github.com/Illumina/manta" rel="nofollow">https://github.com/Illumina/manta</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/17926/orange-bioinformatics-2534</guid>
	<pubDate>Mon, 06 Oct 2014 12:51:37 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/17926/orange-bioinformatics-2534</link>
	<title><![CDATA[Orange-Bioinformatics 2.5.34]]></title>
	<description><![CDATA[<p>Orange Bioinformatics extends <a href="http://orange.biolab.si/">Orange</a>, a data mining software package, with common functionality for bioinformatics. The provided functionality can be accessed as a Python library or through a visual programming interface (Orange Canvas). The latter is also suitable for non-programmers.</p>
<p>Orange Bioinformatics provides access to publicly available data, like GEO data sets, Biomart, GO, KEGG, Atlas, ArrayExpress, and PIPAx database. As for the analytics, there is gene selection, quality control, scoring distances between experiments with multiple factors. All features can be combined with powerful visualization, network exploration and data mining techniques from the Orange data mining framework.</p><p>Address of the bookmark: <a href="https://pypi.python.org/pypi/Orange-Bioinformatics/2.5.34" rel="nofollow">https://pypi.python.org/pypi/Orange-Bioinformatics/2.5.34</a></p>]]></description>
	<dc:creator>Robert M Willioms</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/37457/nanofilt-filtering-and-trimming-of-long-read-sequencing-data</guid>
	<pubDate>Mon, 30 Jul 2018 12:01:52 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/37457/nanofilt-filtering-and-trimming-of-long-read-sequencing-data</link>
	<title><![CDATA[nanofilt: Filtering and trimming of long read sequencing data]]></title>
	<description><![CDATA[<p>Filtering on quality and/or read length, and optional trimming after passing filters.<br>Reads from stdin, writes to stdout.</p>
<p>Intended to be used:</p>
<ul>
<li>directly after fastq extraction</li>
<li>prior to mapping</li>
<li>in a stream between extraction and mapping</li>
</ul>
<p>https://github.com/wdecoster/nanofilt</p><p>Address of the bookmark: <a href="https://github.com/wdecoster/nanofilt" rel="nofollow">https://github.com/wdecoster/nanofilt</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/18380/jrfsrf-at-university-of-hyderabad</guid>
  <pubDate>Fri, 17 Oct 2014 01:55:44 -0500</pubDate>
  <link></link>
  <title><![CDATA[JRF/SRF at University of Hyderabad]]></title>
  <description><![CDATA[
<p>Applications are invited for the following post of Junior Research Fellow (temporary position coterminous with the project) under DBT funded research project on ““Understanding the functions of α1β1γ1/α2β1γ1 selective AMPK Modulators in dissecting the pharmacological role of these isozymes in metabolic diseases”</p>

<p>Qualified and interested candidates can send their curriculum vitae by e-mail to hr@drils.org on or before 27th October 2014 mention in the subject line of the mail the following code: AMPK-Biology.</p>

<p>Selected candidates will be called for a personal interview to Dr. Reddy’s Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad. The selected candidate is expected to report within two weeks from the date of selection to start work on the project.</p>

<p>Junior Research Fellowship (Molecular Modeling/Biology) for two years and Senior Research fellowship for one year</p>

<p>Junior Research Fellowship: Rs. 15,600/- (consolidated) per month for first two years.<br />Senior Research Fellowship: Rs. 18,200/-(consolidated) per month for the 3rd year.</p>

<p>Duration: The duration of the fellowship is for three years. However, the performance of the candidate will be reviewed after the completion of every year and the fellowship will be renewed only upon satisfactory performance.</p>

<p>Responsibilities:</p>

<p>1) Literature search.<br />2) Design, plan and execute experiments under the supervision of the scientist.<br />3) Provide scientific support to the scientist in his/her research activities.<br />4) Book keeping and maintenance of stocks and consumables.</p>

<p>Essential Qualifications:</p>

<p>Required: M.Sc. in Microbiology/Biotechnology/Bioinformatics or any other related branch of basic Sciences from a recognized university/institute with a consistent academic record of minimum 60% aggregate in all qualifying examinations. The candidate should be NET qualified for lectureship. The candidate should be motivated to work with dedication.</p>

<p>Desirable: expertise/experience in both Molecular Modeling and Molecular Biology.</p>

<p>Experience: 0-2 years in the areas of Molecular Modeling and/or Molecular Biology and cell biology and Biochemistry.</p>

<p>Preferable: Relevant research experience as evident from thesis/dissertation/project work.</p>

<p>Advertisement: http://www.ilsresearch.org/userfiles/Junior%20REsearch%20Fellowship%20-%20AMPK(Biology).pdf</p>
]]></description>
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