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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/26322?offset=680</link>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/32719/download-assemblies-from-ncbi</guid>
	<pubDate>Mon, 15 May 2017 06:02:32 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/32719/download-assemblies-from-ncbi</link>
	<title><![CDATA[Download assemblies from NCBI]]></title>
	<description><![CDATA[<p>A new &ldquo;Download assemblies&rdquo; button is now available in the&nbsp;<a href="https://www.ncbi.nlm.nih.gov/assembly" target="_blank">Assembly</a>&nbsp;database. This makes it easy to download data for multiple genomes without having to write scripts.</p><p>For example, you can run a search in Assembly and use check boxes (see left side of screenshot below) to refine the set of genome assemblies of interest. Then, just open the &ldquo;Download assemblies&rdquo; menu, choose the source database (<a href="https://www.ncbi.nlm.nih.gov/genbank/" target="_blank">GenBank</a>&nbsp;or&nbsp;<a href="https://www.ncbi.nlm.nih.gov/refseq/" target="_blank">RefSeq</a>), choose the file type, and start the download. An archive file will be saved to your computer that can be expanded into a folder containing your selected genome data files.</p><p><img src="https://ncbiinsights.files.wordpress.com/2017/05/download_button.jpg?w=584" alt="image" width="584" height="444" style="border: 0px; border: 0px;"></p><p>&nbsp;</p><p>More at&nbsp;https://ncbiinsights.ncbi.nlm.nih.gov/2017/05/08/genome-data-download-made-easy/</p>]]></description>
	<dc:creator>Bulbul</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/32420/fastq-format</guid>
	<pubDate>Wed, 03 May 2017 04:23:32 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/32420/fastq-format</link>
	<title><![CDATA[Fastq format]]></title>
	<description><![CDATA[<p><strong>FASTQ format</strong>&nbsp;is a text-based&nbsp;<a href="https://en.wikipedia.org/wiki/File_format" title="File format">format</a>&nbsp;for storing both a biological sequence (usually&nbsp;<a href="https://en.wikipedia.org/wiki/Nucleotide_sequence" title="Nucleotide sequence">nucleotide sequence</a>) and its corresponding quality scores. Both the sequence letter and quality score are each encoded with a single&nbsp;<a href="https://en.wikipedia.org/wiki/ASCII" title="ASCII">ASCII</a>&nbsp;character for brevity.</p>
<p>It was originally developed at the&nbsp;<a href="https://en.wikipedia.org/wiki/Wellcome_Trust_Sanger_Institute" title="Wellcome Trust Sanger Institute">Wellcome Trust Sanger Institute</a>&nbsp;to bundle a&nbsp;<a href="https://en.wikipedia.org/wiki/FASTA_format" title="FASTA format">FASTA</a>&nbsp;sequence and its quality data, but has recently become the&nbsp;<em>de facto</em>&nbsp;standard for storing the output of high-throughput sequencing instruments such as the&nbsp;<a href="https://en.wikipedia.org/wiki/Illumina_(company)" title="Illumina (company)">Illumina</a>&nbsp;Genome Analyzer.<sup id="cite_ref-Cock2009_1-0"><a href="https://en.wikipedia.org/wiki/FASTQ_format#cite_note-Cock2009-1">[1]</a></sup></p><p>Address of the bookmark: <a href="https://en.wikipedia.org/wiki/FASTQ_format" rel="nofollow">https://en.wikipedia.org/wiki/FASTQ_format</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/36594/fragscaff-genome-assembly-with-contiguity-preserving-transposition</guid>
	<pubDate>Mon, 14 May 2018 04:28:14 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/36594/fragscaff-genome-assembly-with-contiguity-preserving-transposition</link>
	<title><![CDATA[fragScaff: Genome Assembly with Contiguity Preserving Transposition]]></title>
	<description><![CDATA[<p>Contiguity preserving transposition and sequencing (CPT-seq) is an entirely in vitro means of generating libraries comprised of 9216 indexed pools, each of which contains thousands of sparsely sequenced long fragments ranging from 5 kilobases to &gt;1 megabase. This software, fragScaff, leverages coincidences between the content of different pools as a source of contiguity information for scaffolding de novo genome assemblies. FragScaff is complementary to Lachesis, providing midrange contiguity to support robust, accurate chromosome-scale de novo genome assemblies without the need for laborious in vivo cloning steps.</p>
<p>Further information about fragScaff, including source code, is available at:<a href="https://sourceforge.net/projects/fragscaff/files/">https://sourceforge.net/projects/fragscaff/files</a>.</p>
<p>Manuscript describing fragScaff was published as: Adey A, Kitzman JO, Burton JN, Daza R, Kumar A, Christiansen L, Ronaghi M, Amini S, L Gunderson K, Steemers FJ, Shendure J#.&nbsp;<em>In vitro, long-range sequence information for de novo genome assembly via transposase contiguity.</em>&nbsp;Genome Research 2014 Dec;24(12):2041-9. doi:&nbsp;<a href="http://dx.doi.org/10.1101/gr.178319.114">10.1101/gr.178319.114</a>. PubMed PMID:&nbsp;<a href="http://www.ncbi.nlm.nih.gov/pubmed/25327137">25327137</a>.</p>
<p>&nbsp;</p><p>Address of the bookmark: <a href="https://sourceforge.net/projects/fragscaff/files/" rel="nofollow">https://sourceforge.net/projects/fragscaff/files/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/34368/srbioinformatics-analyst-ngs-at-ocimum</guid>
  <pubDate>Fri, 17 Nov 2017 07:50:44 -0600</pubDate>
  <link></link>
  <title><![CDATA[Sr.Bioinformatics Analyst (NGS) at Ocimum]]></title>
  <description><![CDATA[
<p>JOB FUNCTIONBio Tech/R&amp;D/Scientist<br />INDUSTRYBiotechnology/Pharmaceutical/Medicine<br />SPECIALIZATIONBasic Research,Bio-Statistician,Clinical Research<br />QUALIFICATION<br />Any Post Graduate<br />BA (Arts), B.Com. (Commerce), BE/ B.Tech (Engineering), B.Pharm. (Pharmacy), B.Sc. (Science), BL/LLB, BDS (Dental Surgery), B.Ed. (Education), BHM (Hotel Management), BBA/ BBM/ BBS, B.Arch. (Architecture), BCA (Computer Application), Diploma-Other Diploma, B.Plan. (Planning), BGL, B.V.Sc. (Veterinary Science), Other School/ Graduation, BHMS (Homeopathy), BAMS (Ayurveda)<br />Job Description</p>

<p>1.  Must have basic understanding of molecular biology and Genomics.<br />2. Experience in application development or must have expertise in programming using either of Perl/Python.<br />3.  Experience in statistical programming using R/Bioconductor/Matlab.<br />4. Strong concept in statistical and mathematical modelling.<br />5.  Experience in designing and developing the bioinformatics pipeline.<br />6.  Must have minimum 2+ years of hands on experience in NSG data analysis such as RNA-Seq,Exome-Seq ,Chip-Seq and downstream analysis.<br />7. Knowledge in WGS ,WES, Targeted re-sequencing,GWAS and population genomics will be preferred.<br />8. Must have experience working on opensource software/Framework and commercial software for NGS data analysis and reporting.<br />9. Should be aware of handling big data and guiding team members on multiple projects simultaneously.<br />10. Should have experience coordinating with different groups of clinical research scientist for various project requirements.<br />11. Ability to work as team as well as independently with minimal support.</p>

<p>More at http://www3.ocimumbio.com/</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/40208/ragoo-fast-reference-guided-scaffolding-of-genome-assembly-contigs</guid>
	<pubDate>Sun, 27 Oct 2019 00:57:23 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/40208/ragoo-fast-reference-guided-scaffolding-of-genome-assembly-contigs</link>
	<title><![CDATA[RaGOO: Fast Reference-Guided Scaffolding of Genome Assembly Contigs]]></title>
	<description><![CDATA[<p>Alonge M, Soyk S, Ramakrishnan S, Wang X, Goodwin S, Sedlazeck FJ, Lippman ZB, Schatz MC:&nbsp;<a href="https://www.biorxiv.org/content/early/2019/01/13/519637">Fast and accurate reference-guided scaffolding of draft genomes</a>.&nbsp;<em>bioRxiv</em>&nbsp;2019.</p>
<p>RaGOO is a tool for coalescing genome assembly contigs into pseudochromosomes via minimap2 alignments to a closely related reference genome. The focus of this tool is on practicality and therefore has the following features:</p>
<ol>
<li>Good performance. On a MacBook Pro using Arabidopsis data, pseudochromosome construction takes less than a minute and the whole pipeline with SV calling takes ~2 minutes.</li>
<li>Intact ordering and orienting of contigs.</li>
<li><a href="https://github.com/malonge/RaGOO/wiki/Misassembly-Correction">Misassembly correction</a></li>
<li><a href="https://github.com/malonge/RaGOO/wiki/GFF-File-Lift-Over">GFF lift-over</a></li>
<li><a href="https://github.com/malonge/RaGOO/wiki/Calling-Structural-Variants">Structural variant calling with and integrated version of Assemblytics</a></li>
<li>Confidence scores associated with the grouping, localization, and orientation for each contig.</li>
</ol><p>Address of the bookmark: <a href="https://github.com/malonge/RaGOO" rel="nofollow">https://github.com/malonge/RaGOO</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/pages/view/40228/bioinformatics-services-cro-services</guid>
	<pubDate>Wed, 06 Nov 2019 00:33:11 -0600</pubDate>
	<link>https://bioinformaticsonline.com/pages/view/40228/bioinformatics-services-cro-services</link>
	<title><![CDATA[Bioinformatics Services / CRO Services]]></title>
	<description><![CDATA[<p>RASA is set to provide premium technical and scientific services in a form of solutions, product development and training. .We are also very proficient in providing the high quality Research &amp; Development services in life science informatics field like Next Generation Sequencing (NGS) Data Analysis,Computational Drug Discovery, Bioinformatics, Chemo-informatics and BIO-IT.</p><p>RASA offers faster, better and cost effective cutting edge technology solutions to chemical and life science research and industry. We provide our customers with A seamless model of wide expertise and comprehensive platforms. Our Value is to take our customers</p>]]></description>
	<dc:creator>RASA Life Sciences</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/843/structural-polymorphism-analysis-from-ngs-data</guid>
  <pubDate>Sat, 13 Jul 2013 17:12:47 -0500</pubDate>
  <link></link>
  <title><![CDATA[Structural polymorphism analysis from NGS data]]></title>
  <description><![CDATA[
<p>The LabEx BASC (Biodiversity, Agroecosystems, Society, Climate), a network of 13 laboratories of the Paris-Saclay Scientific Cluster, is seeking a bioinformatician to analyze Next Generation Sequencing (NGS) data analysis. In the context of a flagship project aiming at understanding and improving the adaptive capacity of agroecosystems it will be critical to establish a link between sequence variation, functional variation, gene/protein expression and phenotypic adaptation.</p>

<p>The successful candidate will be in charge of the detection of polymorphisms including structural variants, of the comparison of multiple and diverse genomes of a same species and of the construction of pan- and core-genomes. These challenging tasks will require bioinformatics developments and implementation of methods for accommodating the high level of repetitiveness of complex genomes. The tools will be integrated into pipelines and made available to end-users through the Galaxy platform. The bioinformatician will therefore also have to provide researchers with advices on their experimental designs in order to ensure compliance of produced datasets with pipelines requirements. He/she will be hosted by a bioinformatics/informatics team (7 people) (http://moulon.inra.fr/index.php/fr/equipestransversales/atelier-de-bioinformatique) which has computational facilities and expertise in NGS data analysis, and will benefit as well from national and international collaborative networks (Aplibio http://www.renabi.fr/platforms/aplibio/, Transplant http://transplantdb.eu, AMAIZING http://www.amaizing.fr/).</p>

<p>The position requires a doctoral degree (PhD) in bioinformatics with strong expertise in script writing (Python/Perl) and pipeline development. </p>

<p>Applicants should send a CV and the names of 2 referees willing to provide a letter of recommendation to joets@moulon.inra.fr.</p>
]]></description>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/914/welch-lab</guid>
  <pubDate>Mon, 15 Jul 2013 18:21:13 -0500</pubDate>
  <link></link>
  <title><![CDATA[Welch Lab]]></title>
  <description><![CDATA[
<p>They are based in the Department of Genetics at the University of Cambridge. </p>

<p>The research covers diverse areas of evolutionary biology, and molecular evolution in particular. It combines theoretical and empirical approaches, and particularly evolutionary inference from genome sequence data.</p>

<p>Links @ http://www.gen.cam.ac.uk/research/welch/GroupPage/Home.html</p>
]]></description>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/42402/two-postdoc-positions-to-study-multiscale-genome-evolution-and-cephalopod-gene-regulation-university-of-vienna-austria</guid>
  <pubDate>Thu, 17 Dec 2020 11:45:16 -0600</pubDate>
  <link></link>
  <title><![CDATA[Two postdoc positions to study multiscale genome evolution and cephalopod gene regulation (University of Vienna, Austria)]]></title>
  <description><![CDATA[
<p>Vienna Biocenter are seeking two postdoctoral researchers to join our team and work on the ERC funded project "METASCALE: Modes of genome evolution during major metazoan transitions". The task of both positions will be to study co-evolutionary trends within animal genomes and their association with the emergence of new gene regulation. Our group employs methods of comparative and regulatory genomics to study the regulatory impact of transitions in animal genome architecture. More recently, we have identified a major genome reorganization in the "smart" coleoid cephalopod molluscs (squid, octopus, cuttlefish) that, together with other genomic changes, potentially comprises a unique path or mode of genome evolution among animals. We are thus interested in quantifying these modes of genome evolution across all available animal genomes and to test whether their shifts are associated with the emergence of novel regulation (e.g., in cephalopods). One of our main model species is the Hawaiian bobtail squid species Euprymna scolopes.  The tasks of the two candidates will be complimentary and highly collaborative with one position focusing on comparative genomics analyses across all metazoans and the other position on regulatory genomics in the squid. A solid background in in bioinformatics and comparative genomics is highly desired for the first position, whereas the second position will benefit from experience in molecular and regulatory genomics methods such as HiC, ATAC-seq, RNA-seq or single cell transcriptomics.</p>

<p>The postdocs will join an international group and network of researchers at the University of Vienna studying a diverse range of species and questions in molecular evolution, development, morphology and genomics. Our group is also part of the large evolVienna network of more than 50 evolutionary biology labs in Vienna, across several universities and research institutes. Our Faculty will be relocating to a new campus at the Vienna Biocenter in summer 2021 (https://biologiezentrum.univie.ac.at/en/). Vienna is a vibrant historic European capital with a high QOL. Information about postdoctoral salaries in Austria can be found on this webpage: https://www.fwf.ac.at/en/research-funding/personnel-costs/</p>

<p>Earliest start date will be after July 2021. Initial term of employment is for two years with the possibility of extension. Remote working, at least initially, is a possibility.</p>

<p>Requirements:<br />- PhD degree or equivalent by the start date <br />- Publishing record in peer-reviewed journals or evidence thereof <br />- At least 2 letters of support</p>

<p>Applications including a letter of motivation should be submitted via the Job Center to the University of Vienna (https://personalwesen.univie.ac.at/en/jobs-recruiting/job-center/,<br />job reference number 11615).</p>

<p>Application deadline: January 15th 2021.<br />Application link: https://univis.univie.ac.at/ebewerbung</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/1212/computational-proteomics-lets-remember-the-basics</guid>
	<pubDate>Thu, 01 Aug 2013 17:24:20 -0500</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/1212/computational-proteomics-lets-remember-the-basics</link>
	<title><![CDATA[Computational Proteomics : Lets remember the basics]]></title>
	<description><![CDATA[<p>I spend some of my valuable time in computational drug designing sector. I remember my initial proteomics days, playing with interactive protein visualization software and dreaming big. Fortunately or unfortunately, I switched to genomics and handling the genomic floods in Petabytes which is expected to be in Brontobytes in coming years. Did I mention Brontobytes ??? Let me call to my server personnel &hellip; it gonna tsunami !!!!!</p><p>Today, refreshing my old memories I decided to blog about the basic knowledge of biochemistry and computational proteomics&nbsp;skills, but after I found several article on internet saying exactly what I had wanted to say I thought I might as well just redirect BOL's blog readers there instead:</p><p>Here is the list of website and videos links which provide a good resource for you basic chemistry need:</p><p><a href="http://tecreativ.blogspot.co.uk/2012/09/funny-shortcut-remember-periodic-table.html"></a><a href="http://tecreativ.blogspot.co.uk/2012/09/funny-shortcut-remember-periodic-table.html"></a><a href="http://tecreativ.blogspot.co.uk/2012/09/funny-shortcut-remember-periodic-table.html"></a><a href="http://tecreativ.blogspot.co.uk/2012/09/funny-shortcut-remember-periodic-table.html">http://tecreativ.blogspot.co.uk/2012/09/funny-shortcut-remember-periodic-table.html</a></p><p>This blog have some specific hindi word to remember entire periodic table. I really like</p><p>Group 14 (C Si Ge Sn Pb) -&gt; Sentence &ldquo;<strong>C</strong>hemistry&nbsp;<strong>Si</strong>r&nbsp;<strong>G</strong>iv<strong>e</strong>s&nbsp;<strong>S</strong>a<strong>n</strong>ki&nbsp;<strong>P</strong>ro<strong>b</strong>lems&rdquo;</p><p>Sanki is a hindi word which mean crazy :P</p><p>I found this link useful as well&nbsp;<a href="http://www.wikihow.com/Memorise-the-Periodic-Table"></a><a href="http://www.wikihow.com/Memorise-the-Periodic-Table"></a><a href="http://www.wikihow.com/Memorise-the-Periodic-Table"></a><a href="http://www.wikihow.com/Memorise-the-Periodic-Table">http://www.wikihow.com/Memorise-the-Periodic-Table</a></p><p>The eagle genomics group provide an element of bioinformatics in periodic tables. Yes you got it, this is not periodic table rather bioinformatics tools with periodicals</p><p><a href="http://elements.eaglegenomics.com/"></a><a href="http://elements.eaglegenomics.com/"></a><a href="http://elements.eaglegenomics.com/"></a><a href="http://elements.eaglegenomics.com/">http://elements.eaglegenomics.com/</a></p><p>You can also try this video links, which provide you an overview with tricks on periodic tables:</p><p><a href="http://www.youtube.com/watch?v=fLSfgNxoVGk"></a><a href="http://www.youtube.com/watch?v=fLSfgNxoVGk"></a><a href="http://www.youtube.com/watch?v=fLSfgNxoVGk"></a><a href="http://www.youtube.com/watch?v=fLSfgNxoVGk">http://www.youtube.com/watch?v=fLSfgNxoVGk</a></p><p><a href="http://www.youtube.com/user/periodicvideos"></a><a href="http://www.youtube.com/user/periodicvideos"></a><a href="http://www.youtube.com/user/periodicvideos"></a><a href="http://www.youtube.com/user/periodicvideos">http://www.youtube.com/user/periodicvideos</a></p><p>For drug design educational material, software, tools, databses, viewer, file format and many more stuff at one place&nbsp;<a href="http://www.allfordrugs.com/drug-design/.%C2%A0I"></a><a href="http://www.allfordrugs.com/drug-design/"></a><a href="http://www.allfordrugs.com/drug-design/"></a><a href="http://www.allfordrugs.com/drug-design/">http://www.allfordrugs.com/drug-design/</a>&nbsp;I highly recommend you all computational drug designer to bookmark this page for future studies as well.</p><p>I just remember one of my mini project in which I use my flash knowledge (flash .. oh ya flash) to explain amino acids in interactive and user friendly manner. I can&rsquo;t provide It right now, but promise you to provide a link in near future. I hope that you will enjoy my flashy creative skills :).</p><p>Moreover, I found some of very interesting tricks to remember all amino acids chemical formulae on youtube at</p><p><a href="http://www.youtube.com/watch?v=gqrWb0fmzQ&amp;list=PL6132651E70BB5575"></a><a href="http://www.youtube.com/watch?v=gqrWb0fmzQ&amp;list=PL6132651E70BB5575"></a><a href="http://www.youtube.com/watch?v=gqrWb0fmzQ&amp;list=PL6132651E70BB5575"></a><a href="http://www.youtube.com/watch?v=gqrWb0fmzQ&amp;list=PL6132651E70BB5575">http://www.youtube.com/watch?v=gqrWb0fmzQ&amp;list=PL6132651E70BB5575</a></p><p><a href="http://www.youtube.com/watch?v=C2GfoGXfySQ&amp;list=PL6132651E70BB5575"></a><a href="http://www.youtube.com/watch?v=C2GfoGXfySQ&amp;list=PL6132651E70BB5575"></a><a href="http://www.youtube.com/watch?v=C2GfoGXfySQ&amp;list=PL6132651E70BB5575"></a><a href="http://www.youtube.com/watch?v=C2GfoGXfySQ&amp;list=PL6132651E70BB5575">http://www.youtube.com/watch?v=C2GfoGXfySQ&amp;list=PL6132651E70BB5575</a></p><p><br />Key points for computer added drug designers?<br />1. A shortage of biochemistry skills means that you absolutely nowhere in understanding the key concept and do research.<br />2. Keep handy with complex mathematical formula, before merely running tools or software.<br />3. Dig it better and deeper guys .. design it.</p>]]></description>
	<dc:creator>Jitendra Narayan</dc:creator>
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