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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/26629?offset=1120</link>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/13842/swabs-to-genomes-a-comprehensive-workflow</guid>
	<pubDate>Sun, 10 Aug 2014 03:01:21 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/13842/swabs-to-genomes-a-comprehensive-workflow</link>
	<title><![CDATA[Swabs to Genomes: A Comprehensive Workflow]]></title>
	<description><![CDATA[<p>The sequencing, assembly, and basic analysis of microbial genomes, once a painstaking and expensive undertaking, has become almost trivial for research labs with access to standard molecular biology and computational tools. However, there are a wide variety of options available for DNA library preparation and sequencing, and inexperience with bioinformatics can pose a significant barrier to entry for many who may be interested in microbial genomics. The objective of the present study was to design, test, troubleshoot, and publish a simple, comprehensive workflow from the collection of an environmental sample (a swab) to a published microbial genome; empowering even a lab or classroom with limited resources and bioinformatics experience to perform it.</p><p>Address of the bookmark: <a href="https://peerj.com/preprints/453.pdf" rel="nofollow">https://peerj.com/preprints/453.pdf</a></p>]]></description>
	<dc:creator>Rahul Nayak</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/42804/one-year-position-for-a-bioinformatician-computational-biologist-in-population-genetics</guid>
  <pubDate>Fri, 05 Feb 2021 11:19:02 -0600</pubDate>
  <link></link>
  <title><![CDATA[One-year position for a bioinformatician / computational biologist in population genetics]]></title>
  <description><![CDATA[
<p>The successful candidate will work as support staff mainly in the development, application and maintenance of pipelines for handling large omics datasets (including whole-genome sequences, high-density genotypes and mRNA sequences). These pipelines cover pre-processing of data, statistical analyses and genome bioinformatics. The postholder will also provide support in producing high-level graphic representations of<br />these data and of results from their analysis.  Our team is part of UMR<br />7268 ADES research unit (Anthropologie bio-culturelle, Droit, Ethique<br />et Sant=E9), located at the Timone Faculty of Medicine (Aix-Marseille<br />University, 13005 Marseille). </p>

<p>JOB QUALIFICATION<br />- PhD/Engineer/MSc in bioinformatics, biostatistics, genetics/genomics<br />  or any related field.<br />- Advanced knowledge of Bash/Perl scripting and job management on a Unix<br />  HPC and in at least one basic language for data<br />  manipulation/statistics (such as R/Python/Matlab) are required.<br />- Knowledge of at least one programming language (e.g. C), experience<br />  processing -omics data or skills in advanced graphical representation<br />  of data would be a plus.</p>

<p>DURATION<br />1 year, not extensible</p>

<p>SALARY<br />Gross salary is commensurate with experience and grade (MSc from<br />1,882=80/month and PhD/equivalent from 2,099=80/month).</p>

<p>APPLICATIONS/OPENING<br />Please send a motivation letter, a CV and the names of two referees to<br />pierre.faux@univ-amu.fr. The expected starting date is April 1st, 2021;<br />the job offer will however remain opened until the position is filled.</p>

<p>Pierre Faux</p>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/11175/next-generation-sequencingngs-books</guid>
	<pubDate>Fri, 30 May 2014 04:48:04 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/11175/next-generation-sequencingngs-books</link>
	<title><![CDATA[Next generation sequencing(NGS) books]]></title>
	<description><![CDATA[<p>Employing different technologies, the purpose of NGS platform is to decode the identity or modification on the nucleotides. NGS platforms evolve quickly and capture the main stream.</p>
<p>This bookmark is created to provide NGS online books links.</p><p>Address of the bookmark: <a href="http://en.wikibooks.org/wiki/Next_Generation_Sequencing_%28NGS%29/Print_version" rel="nofollow">http://en.wikibooks.org/wiki/Next_Generation_Sequencing_%28NGS%29/Print_version</a></p>]]></description>
	<dc:creator>Abhimanyu Singh</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/poll/view/23590/will-minion-nanopore-sequencing-increase-the-number-of-next-generation-sequencing-projects</guid>
	<pubDate>Tue, 04 Aug 2015 05:14:07 -0500</pubDate>
	<link>https://bioinformaticsonline.com/poll/view/23590/will-minion-nanopore-sequencing-increase-the-number-of-next-generation-sequencing-projects</link>
	<title><![CDATA[Will MinION Nanopore sequencing increase the number of Next Generation Sequencing projects?]]></title>
	<description><![CDATA[<p>Will MinION Nanopore sequencing increase the number of Next Generation Sequencing projects?</p>]]></description>
	<dc:creator>Strand</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/14758/phd-opportunity-at-universite-de-liege-belgium</guid>
  <pubDate>Mon, 01 Sep 2014 17:16:22 -0500</pubDate>
  <link></link>
  <title><![CDATA[PhD opportunity at Université de Liège - Belgium]]></title>
  <description><![CDATA[
<p>The Bioinformatics and Systems Biology Unit of Université de Liège (Belgium) is looking for a highly motivated master student with programming skills for a PhD thesis project (4 years, fully funded) with the goal of designing computational tools that use literature, genomic and structural data in order to infer regulatory and metabolic networks.  </p>

<p>Applicants are invited to send their resume and a recommendation letter to Prof. Patrick Meyer (more details at   www.biosys.ulg.ac.be )</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/32875/finishing</guid>
	<pubDate>Sat, 20 May 2017 15:50:20 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/32875/finishing</link>
	<title><![CDATA[Finishing !!]]></title>
	<description><![CDATA[<p>The process of&nbsp;<em>finishing</em>&nbsp;a genome and moving it from a&nbsp;<em>draft</em>&nbsp;stage (the result of sequencing and initial assembly) to a complete genome is typically a time and resource intensive task. The advent of new sequencing technologies has come with its own set of opportunities and pitfalls in the finishing process. While genomes can now be sequenced to high redundancy in a cost-effective manner, the process of assembling the genomes is more challenging and often draft genomes are fragmented into hundreds of contigs. Correspondingly, the task of producing the complete genome can involve months of lab work and thousands of finishing experiments and is usually done in large genome centers.</p>
<p>The work in our lab has focussed on computational approaches to speed-up the finishing process. Specifically, we have explored the use of optical mapping and mate-pair data to augment assemblies and direct finishing experiments. The tools developed in our lab have been used in several finishing projects, producing complete genomes (and near-complete ones) with surprisingly little computational and experimental effort (Nagarajan et al., in submission). The executables (as well as source code) for these tools are freely available here:</p>
<ul>
<li><strong>Scaffolding using Optical Restriction Mapping</strong><br>Optical Maps are global, ordered maps of restriction site locations in a genome. This information can be quite useful in scaffolding contigs from a shotgun assembly to guide the finishing process. A set of programs to exploit optical maps for assembly can be found here:&nbsp;<a href="http://www.cbcb.umd.edu/finishing/soma-v2.tar.gz">SOMA v2.0 (63 MB tar.gz file)</a>. This version of SOMA contains several improvements to programs in v1.0 as well as new scripts for working with multiple maps, contig graphs and scaffolds.&nbsp;<br><br></li>
<li><strong>Augmenting assemblies with mate-pair data</strong><br>Mate-pair information can be valuable in augmenting short-read assemblies and reconstructing the genome as larger scaffolds. AMOS-Hybrid is a pipeline written in the AMOS framework (open-source assembly tools) to merge arbitrary mated reads into an existing assembly and merge contigs and create scaffolds where possible. Source code and executables for AMOS-Hybrid are available here:&nbsp;<a href="http://www.cbcb.umd.edu/finishing/AMOS-Hybrid-v1.tar.gz">AMOS-Hybrid v1.0 (142 MB tar.gz file)</a>.&nbsp;<br><br></li>
<li><strong>Assembly and sequence-composition guided finishing</strong><br>Contigs from a shotgun assembly are typically linked together in a graph structure that can serve to guide finishing and in some case close gaps&nbsp;<em>in-silico</em>. Also, in many cases, sequence composition of contigs can provide clues to fill gaps in scaffolds. A set of scripts to automate some of these tasks can be found here:&nbsp;<a href="http://www.cbcb.umd.edu/finishing/finishing-v1.tar.gz">Finishing Scripts v1.0 (63 MB tar.gz file)</a>.&nbsp;</li>
</ul>
<p>http://www.cbcb.umd.edu/finishing/</p><p>Address of the bookmark: <a href="http://www.cbcb.umd.edu/finishing/" rel="nofollow">http://www.cbcb.umd.edu/finishing/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/14905/internship-in-computational-biology</guid>
  <pubDate>Thu, 04 Sep 2014 04:19:40 -0500</pubDate>
  <link></link>
  <title><![CDATA[Internship in Computational Biology]]></title>
  <description><![CDATA[
<p>We are looking for a motivated and autonomous intern to study gene expression in hybrid organisms. The student will work on natural hybrids of two or three different species of fungal endosymbionts of grasses. The pupose of this project is to build software allowing us to identify the genomic origin of expressed genes. To do that, the intern will have to analyze expression data (from RNA-seq) to find SNPs on the sequenced mRNAs allowing to identify from which of the parental genome the expressed gene come from. The data will have to be saved in a database using the standard BioSQL schema.</p>

<p>This job will allow the intern to become more familiar with new biological and bioinformatics tools like next generation sequencing, RNA-Seq data analysis and comparative genomics.</p>

<p>To apply for this position, send the following documents (in PDF format) to Dr Pierre-Yves Dupont (email p.y.dupont@massey.ac.nz):</p>

<p>1. A short cover letter.<br />2. A curriculum vitae, with transcript details.<br />3. The names and contact details of two referees willing to provide a confidential letter of recommendation upon request.</p>

<p>Informal enquiries are welcome. Formal applications are due by Sunday 2nd December 2012.<br />Requirements: </p>

<p>This position requires a good understanding of genetic problems, a good command of at least one scripting language (Perl, Python...), a basic knowledge of MySQL or any relational database management system. Knowledge in biological programming libraries (BioPython, BioPerl, BioRuby...), Java, C++ or any compiled language is an asset but not required. Undergraduate or Master degree is required.<br />Contact Information: </p>

<p>Dr. Pierre-Yves Dupont<br />Institute of Molecular BioSciences<br />Massey University<br />Private Bag 11 222<br />Palmerston North 4442<br />NEW ZEALAND</p>

<p>http://massey.genomicus.com/<br />p.y.dupont@massey.ac.nz</p>

<p>Information about the Institute of Molecular BioSciences (http://imbs.massey.ac.nz/) and the Computational Biology Research Group (http://massey.genomicus.com/) is available online. For more information about the position, you can contact Dr Pierre-Yves Dupont (email p.y.dupont@massey.ac.nz).</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/34493/plast-a-fast-accurate-and-ngs-scalable-bank-to-bank-sequence-similarity-search-tool</guid>
	<pubDate>Fri, 01 Dec 2017 04:10:54 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/34493/plast-a-fast-accurate-and-ngs-scalable-bank-to-bank-sequence-similarity-search-tool</link>
	<title><![CDATA[PLAST: A fast, accurate and NGS scalable bank-to-bank sequence similarity search tool]]></title>
	<description><![CDATA[<p><strong>PLAST is a fast, accurate and NGS scalable bank-to-bank sequence similarity search tool providing significant accelerations of seeds-based heuristic comparison methods, such as the Blast suite of algorithms.</strong></p>
<p><strong>Relying on unique software architecture, PLAST takes full advantage of recent multi-core personal computers without requiring any additional hardware devices.</strong></p>
<p>PLAST stands for&nbsp;<em>Parallel Local Sequence Alignment Search Tool&nbsp;</em>and is was&nbsp;<a href="http://www.biomedcentral.com/1471-2105/10/329" target="_blank">published in BMC Bioinformatics.</a></p>
<p>PLAST is a general purpose sequence comparison tool providing the following benefits:</p>
<ul>
<li>PLAST is a high-performance sequence comparison tool designed to compare two sets of sequences (query vs. reference),</li>
<li>Reduces the processing time of sequences comparisons while providing highest quality results,</li>
<li>Contains a fully integrated data filtering engine capable of selecting relevant hits with user-defined criteria (E-Value, identity, coverage, alignment length, etc.),</li>
<li>Does not require any additional hardware, since it is a software solution. It is easy to install, cost-effective, takes full advantage of multi-core processors and uses a small RAM footprint,</li>
<li>Ready to be used on desktop computer, cluster, cloud as well as within distributed system running Hadoop.</li>
</ul>
<p>https://plast.inria.fr/</p><p>Address of the bookmark: <a href="https://plast.inria.fr/" rel="nofollow">https://plast.inria.fr/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/16158/bioinformatics-position-at-irccs-casa-sollievo-della-sofferenza</guid>
  <pubDate>Wed, 10 Sep 2014 14:25:34 -0500</pubDate>
  <link></link>
  <title><![CDATA[Bioinformatics position at IRCCS Casa Sollievo della Sofferenza]]></title>
  <description><![CDATA[
<p>The bioinformatics unit at IRCCS Casa Sollievo della Sofferenza - Mendel laboratory in Rome is looking for one young bioinformatician with specific experience and/or interest in the analysis of genomics and transcriptomic data.</p>

<p>The candidate will be mainly in charge of developing research on Gene Expression/SNP Arrays data, NGS whole -exome and -transcriptome datasets and biological networks in the contexts of genetic diseases, innovative therapies and regenerative medicine. Main activities will be: (i) data analysis (short-reads mapping, genomics aberrations discovery and annotation, variants pathogenicity detection); (ii) functional/pathway enrichment analysis; (iii) biological networks analysis (artificial knockout, redundancy and lethality analysis, gene set essentiality); (iv) developing of ad-hoc software solutions/routines on clusters of CPUs and GPUs.</p>

<p>The correct cultural background (training in Biology / Computer Science / Statistics or a mix of the three) and a strong interest in working in high throughput data analysis will be considered at the same level of specific experience in the above-mentioned fields.</p>

<p>Knowledge of molecular modeling and simulation and willingness to learn one or more of these languages: python, perl, R, Java, C++, C# is a golden plus. Good knowledge of Scientific English will be positively evaluated for this position, together with good presentation and teamwork skills.</p>

<p>Candidates should send:<br />• a cover letter explaining the role they would like to undertake within the Center, even if it is not listed in this job adv, stating clearly why they would be a good fit to the proposed role, and what they would bring to the Center in terms of expertise, ideas, talent;<br />• a CV including a list of publications;<br />• List of referees.</p>

<p>A CV with one professional reference, details on educational background and of the biological and/or bioinformatic and/or data analysis skills and experience should be sent by email for a preliminary selection to: Tommaso Mazza t.mazza@css-mendel.it</p>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/17187/urdip-bioinformatics-rajrf-vacancies</guid>
  <pubDate>Sat, 20 Sep 2014 20:52:56 -0500</pubDate>
  <link></link>
  <title><![CDATA[URDIP Bioinformatics RA/JRF Vacancies]]></title>
  <description><![CDATA[
<p>CSIR - UNIT FOR RESEARCH AND DEVELOPMENT OF INFORMATION PRODUCTS (CSIR- URDIP)</p>

<p>Adv. No. URDIP/ 6/2014</p>

<p>Opportunity for young Bioinformatics Professionals to make a career in the area of Intellectual Property CSIR has set up a Unit for Research and Development of Information Products (CSIR-URDIP) at Pune to work in the area of scientific informatics. One of the major focus areas of research work at CSIR-URDIP is PATENT INFORMATICS. With the increasing applications of Bioinformatics in the areas of life sciences industry such as Agriculture and Health Care (Diagnostics and Drugs), the output of research in these area is being protected by different forms of Intellectual Property rights. Realizing the importance of IP in the Bioinformatics field, Department of Biotechnology (DBT) has sanctioned a project on “Development, Facilitation and Harvesting of Bioinformatics related Intellectual Property” at CSIR-URDIP.</p>

<p>The project will involve application of Patent Informatics tools and techniques to Bioinformatics (including creation of patent landscapes, preparation of techno-legal reports of patentability, freedom to operate studies) to help protect IPRs and develop and conduct training programmes on IPRs related to Bioinformatics.</p>

<p>CSIR-URDIP invites applications from young Bioinformatics professionals to work on this emerging area which offers challenging opportunities and attractive career possibilities in future.</p>

<p>Position I: Research Associate</p>

<p>No of Positions: One</p>

<p>Consolidated amount Payable: Rs. 22,000/- per month + 20% HRA= Rs.26,400</p>

<p>Qualification:  PhD in Bioinformatics. In exceptional cases, candidature of M. Tech. candidates with First class in Bioinformatics with three years of relevant work experience will also be considered.</p>

<p>Age Limit: 35 years. The age should not exceed the limit indicated as on a closing date of receipt of completed application form.</p>

<p>Upper age limit is relaxable for 5 years for SC/ST, OBC, Physically handicapped and female candidates as per CSIR/Government of India rules.</p>

<p>Position II: Junior Research Fellow</p>

<p>No of Positions: one</p>

<p>Consolidated amount Payable: Rs. 16,000/- + 20% HRA = 19,200</p>

<p>Qualification: M.Sc / BE or equivalent in Bioinformatics with minimum of 55% marks in aggregate Job requirement: Scientific literature and patent search, analysis and Report Writing</p>

<p>Preference: Preference will be given to candidates with knowledge of patents and or 1-2 years of experience + Knowledge of Computers (MS Excel + Word Processing)</p>

<p>Age Limit: 28 years. The age should not exceed the limit indicated as on a closing date of receipt of completed application form.</p>

<p>For details please visit our website (www.urdip.res.in/careers) for further details and apply online by 30th September, 2014.</p>

<p>Advertisement: http://www.urdip.res.in/download/Advt6_2014.pdf</p>
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