Research Assistant Bioinformatics recruitment in National Institute Of Cancer Prevention & Research (ICMR) on Contract basis
Project entitled: “Next generation EGFR inhibitor identification using ligand based QSAR technique”

Essential: M.Sc. in Bioinformatics or related field. Desirable: Experience in QSAR and structure based drug designing.
Age: 28 years
No.of Post: 1

Pay Scale : Rs.27000

Application format is attached and should be sent by post to Dr. Subhash M Agarwal, Scientist D, Division of Bioinformatics, National Institute of Cancer Prevention & Research (ICMR), Plot No. I-7, Sector-39, Noida 201301 (U.P).

More at http://www.icmr.nic.in/icmrnews/NICPR_Advertisement%20for%20RA.pdf

https://academic.oup.com/nar/article/47/11/e63/5377471

Address of the bookmark: https://github.com/linzhi2013/MitoZ

Run Maq Now

Follow these steps to try Maq. All you need is a reference sequence file in the FASTA format.

1. Prepare a reference sequence (ref.fasta). Better a bacterial genome.
2. Download maq, maq-data and maqview at the download page.
3. Copy maq, maq.pl and maq_eval.pl to the $PATH or to the same directory.
4. Simulate diploid reference and read sequences, map reads, call variants and evaluate the results in one go:

   maq.pl demo ref.fasta calib-30.dat
   

   where calib-30.dat is contained in maq-data.
5. View the alignment:

   cd maqdemo/easyrun;
   maqindex -i -c consensus.cns all.map;
   maqview -c consensus.cns all.map

Even for advanced maq users, running `maq.pl demo' is recommended. You may find something helpful.

Address of the bookmark: http://maq.sourceforge.net

Careful encoding of graph entities allows odgi to efficiently compute and transform pangenomes with minimal overheads. odgi implements a dynamic data structure that leveraged multi-core CPUs and can be updated on the fly.

The edges and path steps are recorded as deltas between the current node id and the target node id, where the node id corresponds to the rank in the global array of nodes. Graphs built from biological data sets tend to have local partial order and, when sorted, the deltas be small. This allows them to be compressed with a variable length integer representation, resulting in a small in-memory footprint at the cost of packing and unpacking.

The RAM and computational savings are substantial. In partially ordered regions of the graph, most deltas will require only a single byte.

Address of the bookmark: https://github.com/pangenome/odgi

About Fellowship:
CSIR Nehru Science Postdoctoral Research Fellowship Scheme is an Research Fellowship awarded/given by HRD Ministry, Govt. of India every year to more than 100 fellows.

It was started to identify promising and young researchers with novel ideas and provide them research opportunities in the areas of basic science, engineering, medicine & agriculture.

The fellowship aims at facilitating their transition from mentored to independent research career.

In addition, check these ICTS Research Fellowships:
1.) Max-Planck Partner Group Fellowships 2017-18
2.) ICTS-Simons Postdoctoral Fellowships 2017
3.) ICTS Post Doctoral Fellowships 2017
4.) Airbus Prize Postdoctoral Fellowship 2017-18

Eligibility: To be eligible for this fellowship, you:
1.) PhD degree (within 3 years of award of PhD degree), OR
2.) Those who have submitted PhD theses.
3.) Applicants should have research publications in good impact factor SCI journals.
4.) Indian nationals, Persons of Indian Origin (PIO) & Overseas Citizen of India (OCI), a can also apply.
5.) Maximum Age Limit: 32 years.

Duration:
– 2 Years.
– extendable for a maximum of 1 more year based on performance.

Remuneration:
– Rs. 50,000/- per month plus House Rent Allowance (HRA)
– A contingency grant of Rs. 3.0 lakh per annum.
– 25% of the contingency grant can be used for domestic and international travel.

Mode of Selection: You can apply throughout the year, but selection will be made twice a year, in June and December.

How to Apply:
– Read the instructions, given at Annexure-I in this PDF file.
– And, application form is given as, Annexure-II.
– Fill the form & send it to the given address in the PDF file.

Deadline: Rolling Deadline (Applications accepted throughout the year)

Also See: Research Internship/ Fellowship in India:
1.) IIT Bombay Research Internship Awards Programme 2016-17
2.) IIT Delhi Internship Program 2016-17
3.) DAAD WISE – International Internship in Germany
4.) Summer Research Fellowship Programme| JNCASR Bangalore
5.) Indian Academy of Sciences Summer Internships 2017
6.) Winter Internship – IIT Bombay NPDE-TCA
7.) Viterbi – India Program 2017 | Research Internship in US
8.) Internship – Centre for Stem Cell Research, Vellore

Accommodation & other benefits:
– Accommodation may be provided by CSIR, if available.
– Medical benefits as per CSIR norms.

For more details:
– Check this PDF Notification of Fellowship.
– List of CSIR Labs & their work/activities can be seen at www.csir.res.in.

Advertisement for Faculty Positions

The IISER Berhampur, an Institute of national importance, established through an act of Parliament is an autonomous organization under the Ministry of HRD, Govt. of India, to promote quality education and cutting edge research in basic sciences and to provide a platform for the faculty to engage in high quality education, at undergraduate and postgraduate levels. The Institute invites applications for faculty positions at the level of Assistant Professor (C) /Assistant Professor in the following disciplines:

1. Biological Sciences

2. Chemistry

3. Computer Sciences

4. Mathematics

5. Physics

Only hard copy of application in the prescribed format, via Speed Post should be sent to the Dean, Faculty Affairs, IISER Berhampur, Industrial Training Institute (ITI) Berhampur, Engineering School Road, Berhampur - 760 010, Ganjam District, Odisha, before 1700 hrs., December 30, 2016.

http://www.iiserbpr.ac.in

More Info : http://www.iiserbpr.ac.in/vacancies/Advertisement%20for%20Faculty%20Positions%20at%20IISER%20Berhampur.pdf

• AssemblyMapper : reference-guided genome assembly
• GapFiller : long-reads based gap filling
• TeloExplorer : telomere identification
• CentroMiner : centromere candidate prediction

https://academic.oup.com/hr/article/10/8/uhad127/7197191?login=false 

Address of the bookmark: http://www.atcgn.com:8080/quarTeT/home.html

http://compbio.cs.toronto.edu/prism/

Address of the bookmark: http://compbio.cs.toronto.edu/prism/

More at https://sourceforge.net/projects/sb2nhri/files/MyPro/

Address of the bookmark: http://www.sciencedirect.com/science/article/pii/S0167701215001207

• paired-end (PE) and/or mate-pair libraries (NGS-based mode)
• long reads (NGS-based mode)
• synteny to the genome of some related species (reference-based mode)

Scaffolding 

In reference-based mode, pyScaf uses synteny to the genome of closely related species in order to order contigs and estimate distances between adjacent contigs.

Contigs are aligned globally (end-to-end) onto reference chromosomes, ignoring:

• matches not satisfying cut-offs (--identity and --overlap)
• suboptimal matches (only best match of each query to reference is kept)
• and removing overlapping matches on reference.

In preliminary tests, pyScaf performed superbly on simulated heterozygous genomes based on C. parapsilosis (13 Mb; CANPA) and A. thaliana (119 Mb; ARATH) chromosomes, reconstructing correctly all chromosomes always for CANPA and nearly always for ARATH (Figures in dropbox, CANPA table, ARATH table).
Runs took ~0.5 min for CANPA on 4 CPUs and ~2 min for ARATH on 16 CPUs.

Important remarks:

• Reduce your assembly before (fasta2homozygous.py) as any redundancy will likely break the synteny.
• pyScaf works better with contigs than scaffolds, as scaffolds are often affected by mis-assemblies (no de novo assembler / scaffolder is perfect...), which breaks synteny.
• pyScaf works very well if divergence between reference genome and assembled contigs is below 20% at nucleotide level.
• pyScaf deals with large rearrangements ie. deletions, insertion, inversions, translocations. Note however, this is experimental implementation!
• Consider closing gaps after scaffolding.

Address of the bookmark: https://github.com/lpryszcz/pyScaf