This book is suitable for classroom use as a general introduction to programming concepts.

More at http://tldp.org/LDP/abs/html/

Address of the bookmark: http://tldp.org/LDP/abs/html/

Eligibility : MSc, M Phil / Phd, BE/B.Tech

Location : Delhi

Last Date : 08 Mar 2016

Hiring Process : Walk - In
Regional Medical Research Centre -

Notification Order No.1-51/Proj/RMRC/PB/

Scientist – II (Post Code: BIC-II) job position in Regional Medical Research Centre (ICMR)

Essential Qualification: 1 st class Master’s degree in Bioinformatics / Computational Biology. B.E / B.Tech (Bioinformatics / Computer Science / Biotechnology) OR 2nd Class M.Sc. with Ph.D. in Bioinformatics / Computational Biology / Life Science.

Desirable Qualification: Post-doctoral research experience in Bioinformatics / Computational Biology / Computer Science / Life Science at a recognized institution. Experience in handling and analyzing sequencing data. Experience in scripting languages (PERL/PYTHON) etc./ Statistical software. Experience in developing research projects.

Number of Post: 1 UR

Place of Posting: RMRC, Port Blair

Age Limit: 40 years

Pay Scale : Rs.45,954
How to apply

Interested candidates are invited to submit applications along with copies of all the certificates of educational qualifications, date of birth, working experience etc . on the affixing a passport size photograph by Application Format to attend a walk-in interview on 8th March 2016 at 10:30 AM.

More at http://www.icmr.nic.in/icmrnews/port%20blair%20Bioinf%2003-2016.pdf

JRF jobs in International Centre for Genetic Engineering and Biotechnology

Area of research: Computational analysis of protein-protein interactions and metabolic reconstruction of pathways

Qualification : Suitable candidate must have completed Masters in Computer Science/Physics/Mathematics/Bioinformatics or PG diploma in Bioinformatics with very sound programming skills shown in the form of completed project or paper. Programming Skill required: Java/perl/python or any other scripting language and working knowledge of MySQL. Candidate should have some familiarity with R statistical package.

The salary will be as per the guidelines of DBT/DST, based on qualification and experience.

How to apply

Interested candidates may send application along with CV via email to hemant@icgeb.res.in (Dr. Hemant Ritturaj Kushwaha) on or before 08/03/2016. Candidates applying through Email must mention “Application for JRF” in their subject line.

More at http://www.icgeb.org/vacancies.html

The Program Officer, Bioinformatics, operating under the Senior Advisor for Metagenomics & Lab Systems, will play a pivotal role in leveraging bioinformatics to advance the objectives of the Health Security and AMR program. This position offers a unique opportunity to contribute to cutting-edge genomics research and its application in public health.

More detail at https://jobs-jhpiego.icims.com/jobs/5440/program-officer-%e2%80%93-bio-informatics/job

PEAR evaluates all possible paired-end read overlaps and without requiring the target fragment size as input. In addition, it implements a statistical test for minimizing false-positive results. Together with a highly optimized implementation, it can merge millions of paired end reads within a couple of minutes on a standard desktop computer.

More at http://www.exelixis-lab.org/web/software/pear

Paper: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933873/

Address of the bookmark: http://www.exelixis-lab.org/web/software/pear

1. Setting up your computing environment
2. Retrieving and storing sequencing files (your own data or from public sources)
3. Checking sequence quality, trimming, general sequence manipulation
4. Mapping reads to a reference genome
5. Manipulating SAM/BAM alignment files
6. Visualizing data in a genome browser

RNA-Seq

1. De novo transcript discovery and differential analysis with Cufflinks
2. Differential expression analysis with R/Bioconductor
3. Clustering of large expression datasets (microarray or RNA-Seq)

Microarray

1. Basic analysis of Affymetrix Gene Expression Arrays using R/Bioconductor

General Tips for Data Analysis

1. Excel workarounds, adding gene annotation, X-Y plots tips, etc.

Address of the bookmark: http://homer.salk.edu/homer/basicTutorial/

Experience Required: 3-5 years of experience
No of Positions : Multiple
Qualifications: Candidates with minimum qualification as M.Sc Bioinformatics with 3-5 years of experience in Life sciences R&D or Pharma Industry.
Ph.D candidates with research experience in Bioinformatics with publications in International journal and minimum 2 years of industry experience in clinical genomics will be preferred for this position.

Requirement:

1. Must have basic understanding of molecular biology and Genomics.
2. Experience in application development or must have expertise in programming using either of Perl/Python.
3. Experience in statistical programming using R/Bioconductor/Matlab.
4. Strong concept in statistical and mathematical modelling.
5. Experience in designing and developing the bioinformatics pipeline.
6. Must have minimum 2+ years of hands on experience in NSG data analysis such as RNA-Seq,Exome-Seq ,Chip-Seq and downstream analysis.
7. Knowledge in WGS ,WES, Targeted re-sequencing,GWAS and population genomics will be preferred.
8. Must have experience working on opensource software/Framework and commercial software for NGS data analysis and reporting.
9. Should be aware of handling big data and guiding team members on multiple projects simultaneously.
More at http://www.ocimumbio.com/careers1/
10. Should have experience coordinating with different groups of clinical research scientist for various project requirements.
11. Ability to work as team as well as independently with minimal support.

Main features of YASS are:

• multiple, possibly overlapping seeds and a new hit criterion to ensure a good sensitivity/selectivity trade-off
• transition-constrained spaced seeds to improve sensitivity (transition mutations are purine to purine [A<->G] or pyrimidine to pyrimidine [C<->T])
• using different scoring schemes with bit-score and E-value evaluated according to the sequence background frequencies
• parameterizable output filter for low complexity repeats
• reporting of various alignment statistical parameters (mutation bias along triplets, transition/transversion)
• post-processing step to group gapped alignments

Address of the bookmark: http://bioinfo.lifl.fr/yass/

If you are using Windows you can easily upgrade to the latest version of R using the installr package. Simply run the following code in Rgui:

install.packages("installr") # install 
setInternet2(TRUE)
installr::updateR() # updating R.

Running “updateR()” will detect if there is a new R version available, and if so it will download+install it (etc.). There is also a step by step tutorial (with screenshots) on how to upgrade R on Windows, using the installr package. If you only see the option to upgrade to an older version of R, then change your mirror or try again in a few hours (it usually take around 24 hours for all CRAN mirrors to get the latest version of R).

I try to keep the installr package updated and useful, so if you have any suggestions or remarks on the package – you are invited to open an issue in the github page.

More at http://www.sanger.ac.uk/science/groups/lawley-lab