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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/27070?offset=780</link>
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	<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/26911/raca-reference-assisted-chromosome-assembly</guid>
	<pubDate>Wed, 06 Apr 2016 09:29:50 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/26911/raca-reference-assisted-chromosome-assembly</link>
	<title><![CDATA[RACA: Reference-Assisted Chromosome Assembly]]></title>
	<description><![CDATA[<p>Rreference-Assisted Chromosome Assembly (RACA), an algorithm to reliably order and orient sequence scaffolds generated by NGS and assemblers into longer chromosomal fragments using comparative genome information and paired-end reads.</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/23307812</p>
<p>http://bioen-compbio.bioen.illinois.edu/RACA/</p><p>Address of the bookmark: <a href="http://bioen-compbio.bioen.illinois.edu/RACA/" rel="nofollow">http://bioen-compbio.bioen.illinois.edu/RACA/</a></p>]]></description>
	<dc:creator>Priya Singh</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/26975/trimmomatic-a-flexible-read-trimming-tool-for-illumina-ngs-data</guid>
	<pubDate>Fri, 15 Apr 2016 05:58:53 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/26975/trimmomatic-a-flexible-read-trimming-tool-for-illumina-ngs-data</link>
	<title><![CDATA[Trimmomatic: A flexible read trimming tool for Illumina NGS data]]></title>
	<description><![CDATA[<h4>Paired End:</h4>
<p><code>java -jar trimmomatic-0.35.jar PE -phred33 input_forward.fq.gz input_reverse.fq.gz output_forward_paired.fq.gz output_forward_unpaired.fq.gz output_reverse_paired.fq.gz output_reverse_unpaired.fq.gz ILLUMINACLIP:TruSeq3-PE.fa:2:30:10 LEADING:3 TRAILING:3 SLIDINGWINDOW:4:15 MINLEN:36</code></p>
<p>This will perform the following:</p>
<ul>
<li>Remove adapters (ILLUMINACLIP:TruSeq3-PE.fa:2:30:10)</li>
<li>Remove leading low quality or N bases (below quality 3) (LEADING:3)</li>
<li>Remove trailing low quality or N bases (below quality 3) (TRAILING:3)</li>
<li>Scan the read with a 4-base wide sliding window, cutting when the average quality per base drops below 15 (SLIDINGWINDOW:4:15)</li>
<li>Drop reads below the 36 bases long (MINLEN:36)</li>
</ul>
<p>More at http://www.usadellab.org/cms/?page=trimmomatic</p><p>Address of the bookmark: <a href="http://www.usadellab.org/cms/?page=trimmomatic" rel="nofollow">http://www.usadellab.org/cms/?page=trimmomatic</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/27046/desai-lab</guid>
  <pubDate>Thu, 21 Apr 2016 10:21:07 -0500</pubDate>
  <link></link>
  <title><![CDATA[Desai Lab]]></title>
  <description><![CDATA[
<p>Evolutionary Dynamics and Population Genetics</p>

<p>Natural selection and other evolutionary forces lead to particular patterns of evolutionary dynamics, and they leave characteristic signatures on the genetic variation within populations.  We use a combination of theory and experiments to study the dynamics and population genetics of natural selection in asexual populations such as microbes and viruses. </p>

<p>We use both theory and experiments to study evolutionary dynamics and population genetics, particularly in situations where natural selection is pervasive.</p>

<p>http://desailab.oeb.harvard.edu/home</p>
]]></description>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/27078/homer-software-for-motif-discovery-and-next-gen-sequencing-analysis</guid>
	<pubDate>Tue, 26 Apr 2016 03:48:23 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/27078/homer-software-for-motif-discovery-and-next-gen-sequencing-analysis</link>
	<title><![CDATA[HOMER:  Software for motif discovery and next-gen sequencing analysis]]></title>
	<description><![CDATA[<p><span>This tutorial covers topics independently of HOMER, and represents knowledge which is important to know before diving head first into more advanced analysis tools such as HOMER.</span></p>
<ol>
<li><a href="http://homer.salk.edu/homer/basicTutorial/computerSetup.html">Setting up your computing environment</a></li>
<li><a href="http://homer.salk.edu/homer/basicTutorial/retrieveFiles.html">Retrieving and storing sequencing files</a>&nbsp;(your own data or from public sources)</li>
<li><a href="http://homer.salk.edu/homer/basicTutorial/fastqFiles.html">Checking sequence quality, trimming, general sequence manipulation</a></li>
<li><a href="http://homer.salk.edu/homer/basicTutorial/mapping.html">Mapping reads to a reference genome</a></li>
<li><a href="http://homer.salk.edu/homer/basicTutorial/samfiles.html">Manipulating SAM/BAM alignment files</a></li>
<li><a href="http://homer.salk.edu/homer/basicTutorial/genomeBrowsers.html">Visualizing data in a genome browser</a></li>
</ol>
<p><br>RNA-Seq</p>
<ol>
<li><a href="http://homer.salk.edu/homer/basicTutorial/rnaseqCufflinks.html">De novo transcript discovery and differential analysis with Cufflinks</a></li>
<li><a href="http://homer.salk.edu/homer/basicTutorial/rnaseqR.html">Differential expression analysis with R/Bioconductor</a></li>
<li><a href="http://homer.salk.edu/homer/basicTutorial/clustering.html">Clustering of large expression datasets (microarray or RNA-Seq)</a></li>
</ol>
<p><br><span>Microarray</span></p>
<ol>
<li><a href="http://homer.salk.edu/homer/basicTutorial/affymetrix.html">Basic analysis of Affymetrix Gene Expression Arrays using R/Bioconductor</a></li>
</ol>
<p><span>General Tips for Data Analysis</span></p>
<ol>
<li><a href="http://homer.salk.edu/homer/basicTutorial/excelTips.html">Excel workarounds, adding gene annotation, X-Y plots tips, etc.</a></li>
</ol><p>Address of the bookmark: <a href="http://homer.salk.edu/homer/basicTutorial/" rel="nofollow">http://homer.salk.edu/homer/basicTutorial/</a></p>]]></description>
	<dc:creator>Neel</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/27094/smash-an-alignment-free-method-to-find-and-visualise-rearrangements-between-pairs-of-dna-sequences</guid>
	<pubDate>Tue, 26 Apr 2016 12:18:49 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/27094/smash-an-alignment-free-method-to-find-and-visualise-rearrangements-between-pairs-of-dna-sequences</link>
	<title><![CDATA[Smash: An alignment-free method to find and visualise rearrangements between pairs of DNA sequences]]></title>
	<description><![CDATA[<p><strong>Smash is a completely alignment-free method/tool to find and visualise genomic rearrangements</strong><span>. The detection is based on&nbsp;</span><strong>conditional exclusive compression</strong><span>, namely using a FCM (Markov model), of high context order (typically 20). For visualisation, Smash outputs a&nbsp;</span><strong>SVG image</strong><span>, with an&nbsp;</span><strong>ideogram</strong><span>output architecture, where the patterns are represented with several&nbsp;</span><strong>HSV values</strong><span>&nbsp;(only value varies). The method can perform both in small- and large-scale. Nevertheless is more directed to large-scale since that the main aim of the research is to&nbsp;</span><strong>know where the large-scale [chromosomal by chromosome] of several primates was equal/different, having at a glance a map of the entire genomes</strong><span>.</span></p><p>Address of the bookmark: <a href="http://bioinformatics.ua.pt/software/smash/" rel="nofollow">http://bioinformatics.ua.pt/software/smash/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/27104/gatb-genome-analysis-toolbox-with-de-bruijn-graph</guid>
	<pubDate>Thu, 28 Apr 2016 11:16:51 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/27104/gatb-genome-analysis-toolbox-with-de-bruijn-graph</link>
	<title><![CDATA[GATB : Genome Analysis Toolbox with de-Bruijn graph]]></title>
	<description><![CDATA[<p>The&nbsp;<strong><strong>Genome Analysis Toolbox with de-Bruijn graph</strong> (GATB)</strong> provides a set of <a href="https://gatb.inria.fr/gatb-global-architecture/">highly efficient algorithms to analyse NGS data sets</a>. These methods enable the analysis of data sets of any size on multi-core desktop computers, including very huge amount of reads data coming from any kind of organisms such as bacteria, plants, animals and even complex samples (<em>e.g.</em> metagenomes).</p>
<p>More at https://gatb.inria.fr/</p><p>Address of the bookmark: <a href="https://gatb.inria.fr/" rel="nofollow">https://gatb.inria.fr/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/27238/slurm</guid>
	<pubDate>Wed, 04 May 2016 05:13:21 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/27238/slurm</link>
	<title><![CDATA[SLURM]]></title>
	<description><![CDATA[<p><a href="http://www.schedmd.com/">SLURM</a> workload manager software, a free open-source workload manager designed specifically to satisfy the demanding needs of high performance computing.</p>
<p>This page is a <em>HOWTO</em> guide for setting up a <a href="http://www.schedmd.com/">SLURM</a> installation, currently focused on a CentOS 7 Linux OS. Please send feedback to Ole.H.Nielsen /at/ fysik.dtu.dk.</p>
<p>See the <a href="http://www.schedmd.com/">SLURM</a> homepage (also <a href="https://computing.llnl.gov/linux/slurm/">https://computing.llnl.gov/linux/slurm/</a>).</p><p>Address of the bookmark: <a href="https://wiki.fysik.dtu.dk/niflheim/SLURM" rel="nofollow">https://wiki.fysik.dtu.dk/niflheim/SLURM</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/27290/scientists-post-at-monsanto</guid>
  <pubDate>Wed, 11 May 2016 07:58:44 -0500</pubDate>
  <link></link>
  <title><![CDATA[Scientists post at Monsanto]]></title>
  <description><![CDATA[
<p>Sustainable agriculture is at the core of Monsanto. We develop technologies that enable farmers to produce more crops while conserving natural resources. Monsanto scientists are conducting research and development (R&amp;D) to revolutionize plant breeding and biotechnology.</p>

<p>Monsanto is seeking a very talented Genomics Scientistto become an integral member of our Global Pipeline Analytics team with a focus on quantitative genetics. The ideal candidate will have familiarity with modeling and analysis of genetic data sets using a variety of statistical techniques.</p>

<p>Major Responsibilities:<br />- Provide guidance on experimental design for genomic-related experiments<br />- Familiarity with analysis of the following methods: GWS, QTL, eQTL, RNA-Seq<br />- Provide written and oral presentations of methods, results, conclusions, and recommendations to peer and management groups.<br />- Ensure timely delivery and clear communication of results<br />- Develop strong and successful collaborations among various Monsanto enabling teams.</p>

<p>Required Skills:</p>

<p>- PhD degree in Statistics, Biostatistics, Statistical Genetics, Quantitative Genetics, Breeding, Bioinformatics or a related field with 2 years of experience<br />- Working knowledge and experience with one of the following quantitative languages:R, Python, Perl, SAS<br />- Background in Windows and Linux operating systems<br />- Very strong problem solving skills will be required to work well as a member of a dynamic team<br />- Strong verbal and written communication skills.<br />- Demonstrated ability to deliver timely results and be results oriented.<br />- Extensive knowledge of quantitative genetics and experimental design.&nbsp;<br />- Demonstrated track record of solving challenging and complex problems.</p>

<p>Desired Skills/Experience:</p>

<p>- Excellent communication skills, with the ability to summarize complex concepts in language understandable by scientists from a variety of disciplines.<br />- Experience in agronomy and/or plant breeding in vegetables or row crops.</p>

<p>Please apply to<br />https://jobs.monsanto.com/job/st-louis/genomics-scientist/769/2081771</p>
]]></description>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/file/view/27318/sample-binc-question-paper-2016-part2</guid>
	<pubDate>Fri, 13 May 2016 03:42:56 -0500</pubDate>
	<link>https://bioinformaticsonline.com/file/view/27318/sample-binc-question-paper-2016-part2</link>
	<title><![CDATA[Sample BINC question paper 2016 - part2]]></title>
	<description><![CDATA[<p>Download the sample question paper for BINC 2016 - paer II</p>]]></description>
	<dc:creator>Radha Agarkar</dc:creator>
	<enclosure url="https://bioinformaticsonline.com/file/download/27318" length="52024" type="application/pdf" />
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/27331/andi</guid>
	<pubDate>Fri, 13 May 2016 05:16:35 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/27331/andi</link>
	<title><![CDATA[Andi]]></title>
	<description><![CDATA[<p>This is the <code>andi</code> program for estimating the evolutionary distance between closely related genomes. These distances can be used to rapidly infer phylogenies for big sets of genomes. Because <code>andi</code> does not compute full alignments, it is so efficient that it scales even up to thousands of bacterial genomes.</p>
<p>This readme covers all necessary instructions for the impatient to get <code>andi</code> up and running. For extensive instructions please consult the <a href="https://github.com/EvolBioInf/andi/blob/master/andi-manual.pdf">manual</a>.</p>
<p>More at https://github.com/evolbioinf/andi/</p><p>Address of the bookmark: <a href="http://bioinformatics.oxfordjournals.org/content/early/2015/01/13/bioinformatics.btu815.full" rel="nofollow">http://bioinformatics.oxfordjournals.org/content/early/2015/01/13/bioinformatics.btu815.full</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>

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