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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/27080?offset=1150</link>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/videolist/watch/18384/big-genomic-data-on-google-cloud-platform</guid>
	<pubDate>Fri, 17 Oct 2014 02:16:00 -0500</pubDate>
	<link>https://bioinformaticsonline.com/videolist/watch/18384/big-genomic-data-on-google-cloud-platform</link>
	<title><![CDATA[Big genomic data on Google Cloud Platform]]></title>
	<description><![CDATA[<iframe width="" height="" src="https://www.youtube-nocookie.com/embed/ExNxi_X4qug" frameborder="0" allowfullscreen></iframe>As the cost of DNA sequencing has dropped, the volume of data produced has risen into the petabytes. Google is working with the genomics community to define a standard API for working with big genomic data sets in the cloud. Building on Google Cloud Platform, we show how to store, process, explore and share genomic data using technologies like BigQuery, AppEngine MapReduce, R and more.]]></description>
	
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/40889/rcorrector-efficient-and-accurate-error-correction-for-illumina-rna-seq-reads</guid>
	<pubDate>Tue, 04 Feb 2020 23:23:16 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/40889/rcorrector-efficient-and-accurate-error-correction-for-illumina-rna-seq-reads</link>
	<title><![CDATA[Rcorrector: efficient and accurate error correction for Illumina RNA-seq reads]]></title>
	<description><![CDATA[<p><span>Rcorrector has an accuracy higher than or comparable to existing methods, including the only other method (SEECER) designed for RNA-seq reads, and is more time and memory efficient. With a 5 GB memory footprint for 100 million reads, it can be run on virtually any desktop or server. The software is available free of charge under the GNU General Public License from&nbsp;</span><a href="https://github.com/mourisl/Rcorrector/" target="_blank">https://github.com/mourisl/Rcorrector/</a><span>.</span></p>
<pre><code>Usage: perl run_rcorrector.pl [OPTIONS]
OPTIONS:
	Required
	-s seq_files: comma separated files for single-end data sets
	-1 seq_files_left: comma separated files for the first mate in the paried-end data sets
	-2 seq_files_right: comma separated files for the second mate in the paired-end data sets
	-i seq_files_interleaved: comma sperated files for interleaved paired-end data sets
	Optional
	-k INT: kmer_length (&lt;=32, default: 23)
	-od STRING: output_file_directory (default: ./)
	-t INT: number of threads to use (default: 1)
	-trim : allow trimming (default: false)
	-maxcorK INT: the maximum number of correction within k-bp window (default: 4)
	-wk FLOAT: the proportion of kmers that are used to estimate weak kmer count threshold, lower for more divergent genome (default: 0.95)
	-ek INT: expected number of kmers; does not affect the correctness of program but affects the memory usage (default: 100000000)
	-stdout: output the corrected reads to stdout (default: not used)
	-verbose: output some correction information to stdout (default: not used)
	-stage INT: start from which stage (default: 0)
		0-start from begining(storing kmers in bloom filter) ;
		1-start from count kmers showed up in bloom filter;
		2-start from dumping kmer counts into a jf_dump file;
		3-start from error correction.</code></pre><p>Address of the bookmark: <a href="https://github.com/mourisl/Rcorrector/" rel="nofollow">https://github.com/mourisl/Rcorrector/</a></p>]]></description>
	<dc:creator>BioStar</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/18579/cluster-innovation-center-university-of-delhi</guid>
  <pubDate>Wed, 22 Oct 2014 10:39:49 -0500</pubDate>
  <link></link>
  <title><![CDATA[CLUSTER INNOVATION CENTER @ UNIVERSITY OF DELHI]]></title>
  <description><![CDATA[
<p>Applications for Pre-selection of  candidates under ‘Institutions Mode’ for DST-ISPIRE Faculty in  Computational Biology/ Systems Biology/ Bioinformatics</p>

<p>Applications are invited for pre-selection  of candidates for Ministry of Science and Technology, Department of Science and Technology INSPIRE Faculty Scheme: a component of “Assured Opportunity for Research Career (AORC)” under INSPIRE in the area of computational Biology/Systems Biology/Bioinformatics.</p>

<p>Candidates having done their B.Tech/B.E.  and or M.Sc./M.Tech in Computer Science or Biotechnology and Ph.D. in Systems/ Computational Biology or Bioinformatics may apply in the following format prescribed by DST to the Director, Cluster Innovation Center, University Stadium, GC Narang Marg, University of Delhi, Delhi -11107. Detials of other qualification, age limits etc., please visit www.inspire-dst.gov.in.</p>

<p>Application on the prescribed format may be submitted by email to director@cic.du.ac.in before October 25, 2014. Selected candidates shall be called for an interview. The date, time and venue of the interview shall be informed by email/telephone. For more information about Cluster Innovation Center, please visit https://ducic.ac.in.</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/41030/slr-superscaffolder-a-scaffold-assemble-pipeline-for-stlfr-reads</guid>
	<pubDate>Fri, 14 Feb 2020 14:23:30 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/41030/slr-superscaffolder-a-scaffold-assemble-pipeline-for-stlfr-reads</link>
	<title><![CDATA[SLR-superscaffolder: A scaffold assemble pipeline for stLFR reads.]]></title>
	<description><![CDATA[<p>This is a scaffold assembler designed for stLFR reads[1]. It uses the link-reads information from stLFR reads to assemble contigs to scaffolds.</p>
<p>Here is an illustration of this pipeline:</p>
<p>&nbsp;<img src="https://github.com/BGI-Qingdao/SLR-superscaffolder/raw/master/image.png" alt="image" style="border: 0px;"></p><p>Address of the bookmark: <a href="https://github.com/BGI-Qingdao/SLR-superscaffolder" rel="nofollow">https://github.com/BGI-Qingdao/SLR-superscaffolder</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/19059/ipython-interactive-notebooks</guid>
	<pubDate>Fri, 07 Nov 2014 12:07:02 -0600</pubDate>
	<link>https://bioinformaticsonline.com/news/view/19059/ipython-interactive-notebooks</link>
	<title><![CDATA[IPython: Interactive notebooks]]></title>
	<description><![CDATA[<p>The IPython Notebook is a web-based interactive computational environment where you can combine code execution, text, mathematics, plots and rich media into a single document.</p><p>These notebooks are normal files that can be shared with colleagues, converted to other formats such as HTML or PDF, etc. You can share any publicly available notebook by using the IPython Notebook Viewer service which will render it as a static web page. This makes it easy to give your colleagues a document they can read immediately without having to install anything.</p><p><img src="http://ipython.org/_images/9_home_fperez_prof_grants_1207-sloan-ipython_proposal_fig_ipython-notebook-specgram.png" width="985" height="916" alt="image" style="border: 0px;"><br /><br />To learn more about using the IPython Notebook, you can visit our example collection, and you can read the documentation for all the details on how to use and configure the system. The Notebook Gallery showcases many interesting notebooks covering a variety of topics, from basic programming to advanced scientific computing.</p><p>&nbsp;</p><p>More http://www.nature.com/news/interactive-notebooks-sharing-the-code-1.16261</p><p>http://ipython.org/ipython-doc/1/interactive/notebook.html</p><p>Reference http://ipython.org/notebook.html</p>]]></description>
	<dc:creator>Rahul Nayak</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/41896/kad-assessing-genome-assemblies-using-k-mer-copies-in-assemblies-and-k-mer-abundance-in-illumina-reads</guid>
	<pubDate>Fri, 19 Jun 2020 07:34:12 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/41896/kad-assessing-genome-assemblies-using-k-mer-copies-in-assemblies-and-k-mer-abundance-in-illumina-reads</link>
	<title><![CDATA[KAD: Assessing genome assemblies using K-mer copies in assemblies and K-mer abundance in Illumina reads]]></title>
	<description><![CDATA[<p>KAD is designed for evaluating the accuracy of nucleotide base quality of genome assemblies. Briefly, abundance of k-mers are quantified for both sequencing reads and assembly sequences. Comparison of the two values results in a single value per k-mer, K-mer Abundance Difference (KAD), which indicates how well the assembly matches read data for each k-mer.</p>
<p><a href="https://render.githubusercontent.com/render/math?math=KAD=log_{2}\begin{pmatrix}\frac{c%2Bm}{m(n%2B1)}\end{pmatrix}" target="_blank"><img src="https://render.githubusercontent.com/render/math?math=KAD=log_{2}\begin{pmatrix}\frac{c%2Bm}{m(n%2B1)}\end{pmatrix}" alt="image" style="border: 0px;"></a></p>
<p>where,&nbsp;<em>c</em>&nbsp;is the count of a k-mer from reads,&nbsp;<em>m</em>&nbsp;is the mode of counts of read k-mers, and&nbsp;<em>n</em>&nbsp;is the copy of the k-mer in the assembly.</p><p>Address of the bookmark: <a href="https://github.com/liu3zhenlab/KAD" rel="nofollow">https://github.com/liu3zhenlab/KAD</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/42477/hifiasm-a-haplotype-resolved-assembler-for-accurate-hifi-reads</guid>
	<pubDate>Thu, 24 Dec 2020 10:03:36 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/42477/hifiasm-a-haplotype-resolved-assembler-for-accurate-hifi-reads</link>
	<title><![CDATA[Hifiasm: a haplotype-resolved assembler for accurate Hifi reads]]></title>
	<description><![CDATA[<p><span>Hifiasm is a fast haplotype-resolved de novo assembler for PacBio Hifi reads. It can assemble a human genome in several hours and works with the California redwood genome, one of the most complex genomes sequenced so far. Hifiasm can produce primary/alternate assemblies of quality competitive with the best assemblers. It also introduces a new graph binning algorithm and achieves the best haplotype-resolved assembly given trio data.</span></p><p>Address of the bookmark: <a href="https://github.com/chhylp123/hifiasm" rel="nofollow">https://github.com/chhylp123/hifiasm</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/19161/niab-molecular-biologybioinformatics-scientistra-openings</guid>
  <pubDate>Thu, 13 Nov 2014 13:37:27 -0600</pubDate>
  <link></link>
  <title><![CDATA[NIAB Molecular Biology/Bioinformatics Scientist/RA Openings]]></title>
  <description><![CDATA[
<p>D. No. 1-121/1, 4th and 5th Floors, Axis Clinicals Building, Miyapur, Hyderabad, Telangana, India- 500 049</p>

<p>Email: admin@niab.org.in Telephones: +91 40 2304 9403 Telefax: +91 40 2304 2740<br />Advertisement No: 5/2014</p>

<p>About NIAB National Institute of Animal Biotechnology (NIAB), Hyderabad, an autonomous institute under the aegis of Department of Biotechnology, Government of India, is aimed to harness novel and emerging biotechnologies and create knowledge in the cutting edge areas for improving animal health and productivity.</p>

<p>Applications are invited for the following temporary research positions to work in ongoing DBTBBSRC sponsored research project entitled “Transcriptome Analysis in Indian buffalo and the Genetics of Innate Immunity” at the National Institute of Animal Biotechnology, Hyderabad.</p>

<p>(A) Project Scientist – Level B (One Position)</p>

<p>Emoluments: Rs. 15600 + GP Rs. 5400 + 30 % HRA p.m. (Total emoluments will be Rs. 49,770/-p.m. for the duration of the project)</p>

<p>Essential Qualification: Candidates having M.V.Sc. in Veterinary Microbiology / Veterinary Pathology / Veterinary Public Health / Ph.D. degree in Life Sciences, Biotechnology, Molecular Biology or any other related field from the recognized university are eligible to apply.</p>

<p>The candidate should have a good academic record and research experience as evidenced from published in standard referred journals / patents.</p>

<p>Desirable: Candidates having research experience in the area of tissue culture, genomics, Transcriptomics and Advanced Molecular Biology will be given preference.</p>

<p>Age Limit: Not exceeding 30 years as on last date of the submission of the application.</p>

<p>(B) Research Associate in Bioinformatics (One position)</p>

<p>Fellowship: Rs. 22,000 + 30 % HRA</p>

<p>Essential Qualification: Candidates having Ph.D. degree or M.Tech. with three years of<br />experience in Bioinformatics, Computational Biology, Biotechnology, Life Sciences or any other related field are eligible to apply.</p>

<p>Desirable: Candidate having research experience in the area of next generation sequencing (NGS) data analysis, Genome wide association studies, Genomic selection, advance genomic data analysis etc., will be given preference. The candidate should have a good academic record and research experience as evidenced from published papers in standard journals / patents.</p>

<p>Age Limit: Not exceeding 30 years as on last date of the submission of the application.</p>

<p>Project Duration: The duration of the project is Three years and the positions are co- terminus with the duration of the project. (Initial appointment will be for one year and further extension will be granted based on annual review).</p>

<p>Mode of submission of application: Only online applications are to be submitted through<br />www.niab.org.in on or before 08 December, 2014. Link for online submission of applications will be available from 10 November 2014.</p>

<p>Advertisement: www.niab.org.in/Notifications/Advt_5_2014/Advt_5_2014.pdf</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/43260/bioinformatics-tools-for-telomere-to-telomere-assembly</guid>
	<pubDate>Tue, 17 Aug 2021 13:17:09 -0500</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/43260/bioinformatics-tools-for-telomere-to-telomere-assembly</link>
	<title><![CDATA[Bioinformatics tools for telomere to telomere assembly !]]></title>
	<description><![CDATA[<p>●&nbsp;<a href="https://github.com/arangrhie/merfin" target="_blank">Merfin</a>&nbsp;&ndash; k-mer-based assembly and variant calling evaluation for improved consensus accuracy (Arang Rhie)<br />●&nbsp;<a href="https://www.biorxiv.org/content/10.1101/2020.11.11.378133v1" target="_blank">PanGenie</a>&nbsp;&ndash; algorithm that leverages a pangenome reference built from haplotype-resolved genome assemblies in conjunction with k-mer count information from raw, short-read sequencing data to genotype a wide spectrum of genetic variation (Tobias Marschall)<br />●&nbsp;<a href="https://github.com/ConesaLab/SQANTI3" target="_blank">SQANTI3</a>&nbsp;&ndash; an automated pipeline for the classification of long-read transcripts that can assess the quality of data and the preprocessing pipeline (Roc&iacute;o Amor&iacute;n de Heged&uuml;s&nbsp;<a href="https://twitter.com/rocioadh" target="_blank">@rocioadh</a>)<br />●&nbsp;<a href="https://github.com/GenomeRIK/tama" target="_blank">tama</a>&nbsp;(Transcriptome Annotation by Modular Algorithms) &ndash; software designed for processing Iso-Seq data and other long-read transcriptome data (Richard Kuo&nbsp;<a href="https://twitter.com/GenomeRIK" target="_blank">@GenomeRIK</a>)<br />●&nbsp;<a href="https://github.com/PacificBiosciences/pbAA" target="_blank">pbaa</a>&nbsp;(PacBio Amplicon Analysis) &ndash; separates complex mixtures of amplicon targets from genomic samples to cluster and generate high-quality consensus sequences from HiFi reads (Zev Kronenberg&nbsp;<a href="https://twitter.com/zevkronenberg" target="_blank">@zevkronenberg</a>)<br />●&nbsp;<a href="https://github.com/yuanyuan929/bellerophon" target="_blank">bellerophon</a>&nbsp;&ndash; analyzes MHC typing and other low-complexity gene amplicon data; performs allele calling while detecting polymorphic sites within the sequences and removing potential chimeric sequence variants (Yuanyuan Cheng&nbsp;<a href="https://twitter.com/Yuanyuan929" target="_blank">@Yuanyuan929</a>)<br />●&nbsp;<a href="https://github.com/amwenger/svpack" target="_blank">svpack</a>&nbsp;&ndash; tools for filtering, comparing, and annotating structural variant (SV) calls in VCF format (Aaron Wenger)<br />●&nbsp;<a href="https://github.com/AntonBankevich/jumboDB" target="_blank">JumboDB</a>&nbsp;&ndash; tool for de Bruijn graph construction (Anton Bankevich&nbsp;<a href="https://twitter.com/AntonBankevich" target="_blank">@AntonBankevich</a>)<br />●&nbsp;<a href="https://github.com/ksahlin/ultra" target="_blank">uLTRA</a>&nbsp;&ndash; tool for splice alignment of long transcriptomic reads to a genome, guided by a database of exon annotations. (Kristoffer Sahlin&nbsp;<a href="https://twitter.com/krsahlin" target="_blank">@krsahlin</a>)<br />●&nbsp;<a href="https://www.biorxiv.org/content/10.1101/2021.01.25.428044v1.full.pdf" target="_blank">LeafGo</a>&nbsp;&ndash; workflow to rapidly produce high-quality de novo plant genomes (Luca Ermini&nbsp;<a href="https://twitter.com/ermini_luca" target="_blank">@ermini_luca</a>)</p><p>Reference:</p><p>https://www.pacb.com/blog/young-investigators-share-stellar-science-career-advice-and-bioinformatics-tools-at-smrt-leiden-2021/</p><p>&nbsp;</p>]]></description>
	<dc:creator>BioStar</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/19249/bioinformatics-jrfrasrf-position-at-panjab-university</guid>
  <pubDate>Wed, 19 Nov 2014 20:19:49 -0600</pubDate>
  <link></link>
  <title><![CDATA[Bioinformatics JRF/RA/SRF position at PANJAB UNIVERSITY]]></title>
  <description><![CDATA[
<p>CENTRE FOR SYSTEMS BIOLOGY &amp; BIOINFORMATICS<br />UIEAST, PANJAB UNIVERSITY, CHANDIGARH</p>

<p>Applications are invited along with complete bio-data and attested copies of certificates of qualifications, experience etc. for the one post of Research Fellow and one post of Program Assistant under PURSE Grant of the University in Centre for Systems Biology &amp; Bioinformatics, UIEAST, Panjab University, Chandigarh which is tenable till the period of<br />the project.</p>

<p>Essential Qualification</p>

<p>For Research Fellow:-</p>

<p>M.Sc. in Systems Biology and Bioinformatics / Life Sciences with minimum 55% marks.</p>

<p>Preference will be given to NET/GATE/ICMR qualified candidates without fellowship however, candidates who have cleared the Panjab University Ph.D. entrance test in Systems Biology &amp; Bioinformatics will also be eligible.</p>

<p>For Program Assistant:-</p>

<p>The candidate must have M.Sc./M.Tech/MCA/PGDCA in Computer Science and must be able to handle LAN, Linex. Preference will be given to the candidate having experience in<br />System Administration.</p>

<p>Emoluments</p>

<p>For Research Fellow Rs. 12,500/- per month (Fixed)<br />For Program Assistant Rs. 12,500/- per month (Fixed)</p>

<p>Applications should be reach on or before 19-11-2014 in the office of the undersigned.</p>

<p>Interview will be held on 21-11-2014 in the office of the Coordinator, Centre for Systems Biology &amp; Bioinformatics, South Campus, Block-3, Sector-25, Panjab University, Chandigarh. No TA/DA will be paid.</p>

<p>Advertisement:</p>

<p>http://jobs.puchd.ac.in/includes/jobs/2014/20141110143634-Advertisement.pdf</p>
]]></description>
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