<![CDATA[BOL: Related items]]> https://bioinformaticsonline.com/related/27113?offset=490 https://bioinformaticsonline.com/bookmarks/view/38304/lordfast-sensitive-and-fast-alignment-search-tool-for-long-noisy-read-sequencing-data Tue, 27 Nov 2018 04:43:57 -0600 https://bioinformaticsonline.com/bookmarks/view/38304/lordfast-sensitive-and-fast-alignment-search-tool-for-long-noisy-read-sequencing-data <![CDATA[lordFAST: sensitive and Fast Alignment Search Tool for LOng noisy Read sequencing Data]]> lordFAST is a sensitive tool for mapping long reads with high error rates. lordFAST is specially designed for aligning reads from PacBio sequencing technology but provides the user the ability to change alignment parameters depending on the reads and application.

lordFAST, a novel long-read mapper that is specifically designed to align reads generated by PacBio and potentially other SMS technologies to a reference. lordFAST not only has higher sensitivity than the available alternatives, it is also among the fastest and has a very low memory footprint.

 

Address of the bookmark: https://github.com/vpc-ccg/lordfast

]]> BioJoker https://bioinformaticsonline.com/opportunity/view/12218/assistant-professor-in-medical-bioinformatics Tue, 24 Jun 2014 01:46:36 -0500 <![CDATA[Assistant Professor in Medical Bioinformatics]]> Advt. No : ME-I/A-IV/03/14
No.of Posts:01 (SC)
Pay Scale:
Pay Band of Rs.15600-39100 + Rs.6000/- GP +NPA @ 25% of Basic Pay +Learning Resource Allowance @ Rs.20,000/-P.A.+ Conveyance Allowance @ Rs. 1650/-P.M.+ Academic Allowance @ Rs.2500/- P.M. and other admissible allowances.
Qualifications:
Area of Specialization:-
Bioinformatics/Computational/Biology/Genomics/ Proteomics/ Structural Biology
1. Postgraduate qualification, e.g. Master’s Degree in Biotechnology/Bioinformatics/ Biophysics.
2. A Doctorate Degree of recognized University/Institute in a basic or allied Medical Science subject e.g. Medical Biotechnology/Biophysics. Bioinformatics/X-ray Crystallography/
Immunology/Structural Biology etc
Experience:
1.Minimum three years teaching and/or research experience in a recognized medical/research Institution in an allied medical subject after obtaining doctorate degree and preferably in Medical
Molecular Biology/ Biophysics/Structural Biology/Genomics and Clinical Proteomics/Computational Biology.
2. Minimum two publication with atleast one in international journal and atleast one as first author
Desirable:-
Consistently excellent scholastic/academic record, demonstrated ability to write grant proposal/(s) successfully, Post Doctoral training in a frontier area of medical Bioinformatics Research and of direct relevance to clinical diagnosis or patient care (preferably from a recognized top-ranking medical institution abroad)
Send your applications to O/O, Deputy Registrar, Recruitment & Establishment Cell, University of Health Sciences, Rohtak by 08.7.2014
For more details,please visit website: http://pgimsrohtak.nic.in/2014%20AP%20Advt.pdf
Last Apply Date: 08 Jul 2014

]]> https://bioinformaticsonline.com/bookmarks/view/42204/g-nest-the-gene-neighborhood-scoring-tool Fri, 25 Sep 2020 20:09:18 -0500 https://bioinformaticsonline.com/bookmarks/view/42204/g-nest-the-gene-neighborhood-scoring-tool <![CDATA[G-NEST: The Gene NEighborhood Scoring Tool]]> The Gene NEighborhood Scoring Tool (G-NEST) combines genomic location, gene expression, and evolutionary sequence conservation data to score putative gene neighborhoods across all window sizes. Primary author of final code = William F. Martin. Example data files are in the separate repository.

Address of the bookmark: https://github.com/dglemay/G-NEST

]]> Neel https://bioinformaticsonline.com/opportunity/view/12582/postdoc-position-at-centre-mediterraneen-de-medecine-moleculaire Sun, 06 Jul 2014 11:23:06 -0500 <![CDATA[Postdoc position at Centre Méditerranéen de Médecine Moléculaire]]> The research group of Dr. Michele Trabucchi at the Centre Méditerranéen de Médecine Moléculaire (C3M) at INSERM U1065 (University of Nice Sophia-Antipolis, France) is seeking candidates for a Postdoctoral fellow position to start on October 2014 for 3 years funded by FRM (Fondation pour la Recherche Médicale).
The broad interest of the lab is in understanding the expression control and function of small RNAs in activated myeloid cells (visit our webpage to check research interests and publications of the group : http://www.unice.fr/c3m/EN/Equipe10.html ).

The work will focus on the functional studies of small RNAs by using next-generation sequencing approaches.

Candidates should hold a Ph.D. degree and have strong background in bioinformatics.
The University of Nice Sophia-Antipolis provides a wide range of facilities and training essential for biomedical research.
Interested applicants should send a PDF with a cover letter stating research interests and qualifications, an updated CV, a summary of previous research experience and contact information for two references to Michele Trabucchi ( mtrabucchi@unice.fr )

]]> https://bioinformaticsonline.com/pages/view/44637/tools-to-access-the-quality-of-your-assembled-genome Thu, 08 Aug 2024 23:31:18 -0500 https://bioinformaticsonline.com/pages/view/44637/tools-to-access-the-quality-of-your-assembled-genome <![CDATA[Tools to access the quality of your assembled genome !]]>
  • FASTA VALIDATOR + SEQKIT RMDUP: FASTA validation
  • GENOMETOOLS GT GFF3VALIDATOR: GFF3 validation
  • ASSEMBLATHON STATS: Assembly statistics
  • GENOMETOOLS GT STAT: Annotation statistics
  • NCBI FCS ADAPTOR: Adaptor contamination pass/fail
  • NCBI FCS GX: Foreign organism contamination pass/fail
  • BUSCO: Gene-space completeness estimation
  • TIDK: Telomere repeat identification
  • LAI: Continuity of repetitive sequences
  • KRAKEN2: Taxonomy classification
  • HIC CONTACT MAP: Alignment and visualisation of HiC data
  • MUMMER → CIRCOS + DOTPLOT & MINIMAP2 → PLOTSR: Synteny analysis
  • MERQURY: K-mer completeness, consensus quality and phasing assessment
    • ]]>     LEGE     https://bioinformaticsonline.com/researchlabs/view/12870/nuclear-dynamics-lab Thu, 17 Jul 2014 15:03:27 -0500 <![CDATA[Nuclear Dynamics Lab]]> Lab focus is to elucidate fundamental principles, new mechanisms, machineries and emergent properties that are involved in maintaining the genome and gene expression programmes for improvements in lifelong health and well-being for all.

    More at http://www.babraham.ac.uk/our-research/nuclear-dynamics/

    ]]>         https://bioinformaticsonline.com/blog/view/45270/when-dna-data-tells-the-wrong-story-crossfit-assist-to-resolve Fri, 04 Sep 2026 03:41:38 -0500 https://bioinformaticsonline.com/blog/view/45270/when-dna-data-tells-the-wrong-story-crossfit-assist-to-resolve <![CDATA[When DNA Data Tells the Wrong Story - CrossFit assist to resolve !]]> Imagine comparing humans and chimpanzees to discover which genes make us different. You have millions of RNA-sequencing reads—but there is a catch: the computer may align these reads more easily to one species' genome than the other.

    Suddenly, a technical error can look like a biological difference.

    This is the problem Kenneth A. Barr and Yoav Gilad tackle with CrossFilt, a new computational tool introduced in Genome Biology journal.

    CrossFilt acts like a careful referee. It keeps only sequencing reads that can be reliably compared across species, filtering out reads that could create alignment bias.

    When tested on human, chimpanzee, and rhesus macaque data, CrossFilt reduced false discoveries and produced more reliable cross-species comparisons.

    The message is simple: before asking what makes species different, we need to make sure our methods aren't creating those differences.

    In genomics, sometimes the most important discovery is finding—and removing—the bias hiding in the data.

    Read more at https://link.springer.com/article/10.1186/s13059-026-04082-2?

    ]]>     BioStar     https://bioinformaticsonline.com/videolist/watch/14218/pimp-your-brain-bioinformatics Wed, 20 Aug 2014 22:09:21 -0500 https://bioinformaticsonline.com/videolist/watch/14218/pimp-your-brain-bioinformatics <![CDATA[Pimp your brain: Bioinformatics]]> Jan Lisec from the Max Planck Institute of Molecular Plant Physiology explains, in this "pimp your brain" episode, what bioinformatics is and why bioinformatics is so important and indispensable for biological research. In the video serial "Pimp your brain" scientists from the Max Planck Institute of Molecular Plant Physiology describe their research. More videos from the 'Pimp your brain' serial are available on www.youtube.com/playlist?list=PL-l9VItC9Gn2Ur2Xj6PTOAkjLUlVPbIOO More videos are available on www.mpimp-golm.mpg.de]]> https://bioinformaticsonline.com/bookmarks/view/33693/circleator Sun, 25 Jun 2017 18:04:32 -0500 https://bioinformaticsonline.com/bookmarks/view/33693/circleator <![CDATA[Circleator]]> The Charm City Circleator--or Circleator for short--is a Perl-based visualization tool developed at the Institute for Genome Sciences in the University of Maryland's School of Medicine. Circleator produces circular plots of genome-associated data, like this one:

    Sample Circleator image

    Common uses of the tool include:

    • Displaying the sequence and/or genes in a GenBank flat file.
    • Highlighting differences and/or similarities in gene content between related organisms.
    • Comparing SNPs and indels between closely-related strains or serovars.
    • Comparing gene expression values across multiple samples or timepoints.
    • Visualizing coverage plots of RNA-Seq read alignments.

    Key Features

    Circleator...

    • Builds on BioPerl and the input file formats that it supports, including:
    • Accepts a number of other commonly-used datatypes and file formats:
      • BSR and TRF output, SAM/BAM files, VCF-encoded SNPs, tab-delimited files
    • Outputs publication-ready figures in the SVG (Scalable Vector Graphics) format.
    • Requires only a single configuration file whose layout mirrors that of the figure itself.
      • Predefined configuration files and "track" types are supplied for common datasets.
      • Advanced features allow limited analyses to be performed as a figure is drawn.
    • Includes an extensive set of regression tests.
    • Offers a prototype web-based GUI (under the "Ringmaster" project.)

    https://github.com/jonathancrabtree/Circleator

    Address of the bookmark: https://github.com/jonathancrabtree/Circleator

    ]]>     Jit     https://bioinformaticsonline.com/researchlabs/view/12989/center-for-molecular-dynamics-nepal-cmdn-nepal Wed, 23 Jul 2014 13:54:51 -0500 <![CDATA[Center for Molecular Dynamics Nepal (CMDN), Nepal]]> Center for Molecular Dynamics Nepal (CMDN), established 2007 prides itself as a research driven nongovernmental organization. Unlike other civil society organizations, CMDN is dedicated entirely to promoting research in the country. With its team of energetic and highly motivated experts, CMDN is now recognized as the leading public health and wildlife research organization of the country.

    More at http://www.cmdn.org.np/main/index.php

    ]]>