BOL: Related items

SocBiN Bioinformatics 2014

Tue, 03 Sep 2013 18:50:20 -0500

14th annual conference in Bioinformatics

Date : June 10-13

Organizers: The Society for Bioinformatics in Northern European countries (SocBiN) and the Norwegian Bioinformatics Platform / ELIXIR.NO

Venue: Department of Informatics, University of Oslo, Norway

Topics:
Tools and technologies for integrative bioinformatics
Metagenomics
Comparative genomics and phylogeny
Post-ENCODE bioinformatics
Gene regulation
Cancer genomes
Marine genomics

Computer experts in biotechnology laboratory

Jit — Wed, 04 Dec 2013 02:11:43 -0600

Only bioinformatician can understand that multiplication and division are different but same thing :)

Disclaimer: This cartoon is solely designed to create humour and fun, not to offend any computer experts.

Key Bioinformatics Scientists

Rahul Agarwal — Wed, 09 Oct 2013 13:37:07 -0500

Address of the bookmark: http://www.iscb.org/iscb-leadership-a-staff-/officers-and-board-directors

Hidden Markov Models, Viterbi Algorithm, Markov Chain Exploration with script

Manisha Mishra — Thu, 14 Nov 2013 13:36:56 -0600

Hidden Markov Models, the Viterbi Algorithm, and CpG Islands (in VB6)

Problem :

The CG island is a stretch of DNA (usually longer than 200 bases) in which the frequency of the CG sequence is higher than other regions. It is also called the CpG island, where "p" simply indicates that "C" and "G" are connected by a phosphodiester bond.

CpG islands are often located around the promoters of housekeeping genes (which are essential for general cell functions) or other genes frequently expressed in a cell. At these locations, the CG sequence is not methylated. By contrast, the CG sequences in inactive genes are usually methylated to suppress their expression. The methylated cytosine may be converted to thymine by accidental deamination. Unlike the cytosine to uracil mutation which is efficiently repaired, the cytosine to thymine mutation can be corrected only by the mismatch repair which is very inefficient. Hence, over evolutionary time scales, the methylated CG sequence will be converted to the TG sequence.

Find step wise explanationand implementation steps at http://dna.cs.byu.edu/bio465/Labs/hmm.shtml

Source code with explanation http://www.tannerhelland.com/1187/hidden-markov-models-viterbi-algorithm-cpg-islands-in-vb6/

Fore detail understanding of HMM read this excellent tutorial http://www.cs.ubc.ca/~murphyk/Software/HMM/labman2.pdf

Viterbi Algo at http://en.wikipedia.org/wiki/Viterbi_path

For firther reading Wiki page http://en.wikipedia.org/wiki/Hidden_Markov_model

On CpG island paper and for indepth understanding http://www.biomedcentral.com/1471-2164/12/S2/S10

If you are more interested in exploring Markov Chain Exploration and understand it with graphical version please visit http://www.planet-source-code.com/vb/scripts/ShowCode.asp?txtCodeId=75049&lngWId=1

Reference:

1.http://www.planet-source-code.com

2. http://www.tannerhelland.com

Bioinformatics infrastructure speed up Indian agriculture

Rahul Agarwal — Tue, 07 Jan 2014 12:44:44 -0600

"Realizing the paradigm shift it can bring about, the government is focusing on increased bioinformatics intervention in agri-sciences. Currently under process, the national grid on bioinformatics is expected make much better sense out of huge genomic" -

http://www.biospectrumindia.com/biospecindia/features/203849/supercomputing-indian-agriculture-fast-track-mode/page/1

Molecular Bioinformatics Lab (MBL)

Tue, 19 Nov 2013 18:23:27 -0600

The main subject of interest in our laboratory is the study of the relationship among sequence, structure, and function in proteins and nucleic acids. Our research can be divided in two major topics:

the study of the sequence-structure relationship
(application -> structure prediction)
the study of the structure-function relationship
(application -> function prediction)

Therefore, anything related to the configuration (sequence) and conformation (structure) in atomic systems of proteins and nucleic acids, and the interaction of these with other elements (function) is of our major interest.

Lab page @ http://melolab.org/mbl/

7th International Conference on Bioinformatics and Computational Biology (BICoB)

Rahul Agarwal — Mon, 06 Oct 2014 16:19:36 -0500

In recent years, computational biology and medical informatics have seen significant advances driven by computational techniques in bioinformatics making bioinformatics and computational biology among the most vibrant research areas. The 7th international conference on Bioinformatics and Computational Biology (BICoB-2015) provides an excellent venue for researchers and practitioners in the fields of bioinformatics and computational biology to present and publish their research results and techniques. The BICoB conference seeks original and high quality papers in the fields of bioinformatics, computational biology, systems biology, medical informatics and the related disciplines. We also encourage work in progress and research results in the emerging and evolutionary computational areas. Computational techniques have already enabled unprecedented advances in modern biology and medicine. Work in the computational methods related to, or with application in, bioinformatics is also encouraged including: data mining, text mining, machine learning, modeling and simulation, pattern recognition, data visualization, biostatistics, .etc. The topics of interest include (and are not limited to):
Genome analysis: Genome assembly, genome annotation, gene finding, alternative splicing, EST analysis and comparative genomics.
Sequence analysis: Multiple sequence alignment, sequence search and clustering, function prediction, motif discovery, functional site recognition in protein, RNA and DNA sequences.
Phylogenetics: Phylogeny estimation, models of evolution, comparative biological methods, population genetics.
Structural Bioinformatics: Structure matching, prediction, analysis and comparison; methods and tools for docking; protein design
Analysis of high-throughput biological data: Microarrays (nucleic acid, protein, array CGH, genome tiling, and other arrays), EST, SAGE, MPSS, proteomics, mass spectrometry.
Genetics and population analysis: Linkage analysis, association analysis, population simulation, haplotyping, marker discovery, genotype calling.
Systems biology: Systems approaches to molecular biology, multiscale modeling, pathways,gene networks.
Computational Proteomics: Filtering and indexing sequence databases, Peptide quantification and identification, Genome annotations via mass spectrometry, Identification of post-translational modifications, Structural genomics via mass spectrometry, Protein-protein interactions, Computational approaches to analysis of large scale Mass spectrometry data, Exploration and visualization of proteomic data, Data models and integration for proteomics and genomics, Querying and retrieval of proteomics and genomics data etc.

Authors of selected high quality papers in BICoB-2015 will be invited to submit extended version of their papers for possible publication in bioinformatics journals (Journal of Bioinformatics and Computational Biology JBCB).

Deadlines:

Paper Submission Deadline October 24, 2014
Notification of Acceptance December 15, 2014
Camera-Ready Manuscript January 16, 2015

Address of the bookmark: http://www.cs.umb.edu/bicob/

Scientist Positions @ Gujarat State Biotechnology Mission

Mon, 25 Nov 2013 10:26:39 -0600

Gujarat State Biotechnology Mission invite applications [Online Only] under various projects* namely Gujarat Biodiversity Gene Bank (BioGene), Gujarat Institute of Genomics (GIG), Gujarat Institute of Bioinformatics [GIBS] and Gujarat Institute of Marine Biotechnology. Eligible candidates can Apply through online application portal.

1 Scientist E 3

50,000/-

M.Sc. in Life sciences or Plant Sciences or Biotechnology or Microbiology or Bioinformatics or Ph.D. from a recognized university in any of above subject.

Minimum 8 Yrs. of experience after M.Sc. or 5 Yrs. of experience after Ph.D. in responsible position of work in R & D in the area of genomics/ conservation biotechnology/bioinformatics/Planning/Scientific Administration in Science and technology organization. Highly qualified in the area of modern biology, as evidenced through research experience and proven ability to carry out work in the area of conservation biotechnology. Age limit not exceeding 40yrs.

2 Scientist B 6

30,000/-

M.Sc. in Life sciences or Plant Sciences or Biotechnology or Microbiology or Bioinformatics or Ph.D. from a recognized university in any of above subject shall be preferred.

Minimum 3 Yrs. of experience after M.Sc. in responsible position of work in R & D in the area of genomics/ conservation biotechnology/ bioinformatics /Planning/Scientific Administration in Science and technology organization. Highly qualified in the area of modern biology, as evidenced through research experience and proven ability to carry out work in the area of conservation biotechnology. Age limit not exceeding 35yrs.

The positions are purely on contractual basis for 11 months. Interested candidates can apply online in specified format available at "http://leogen.in/recruit/" The last date of applying is 24th December, 2013. Applications must be submitted online only. Applications submitted in any other format except online prescribed performa will be rejected. Candidates in service must apply through proper channel. Candidates will be required to provide original documents along with duly filled and signed application Performa, as and when called for interview.

For more details please visit the website URL : http://leogen.in/recruit

Marie Curie PhD position available immediately

Fri, 24 Apr 2015 09:23:57 -0500

Sub-project 10: Development of bioinformatic tools for the analysis of MACE data
Host Organizations GenXPRO (Germany)
Objectives : The ESR will be in charge of standardising pipelines that will be used for RNA-seq and MACE analyses by all the participants. He will be involved in performing next generation sequencing to characterise environmental adaptation. A single pipeline to analyse listerial transcriptomic and proteomic data will be developed and implemented by each partner for the sake of uniformity of all the data produced within List_MAPS. The ESR will be involved in the interpretation of transcriptomic and proteomic data for which pathway analyses and good data visualization will be required. A cytoscape app will be developed as visualization tool.
Expected Results: MACE analysis pipeline. Database. Transcriptome comparisons in selected habitats. Data visualization tool.
Duration (months) 24
Contact Dr. Bjorn ROTTER: rotter@genxpro.de

11. Development of innovative tools for rapid phenotypic characterisation of intraspecific diversity of Listeria monocytogenes (Joint supervision PhD)
Host Organizations BioFilm Control (France) and GenXPRO (Germany)
Objectives
1. The ESR will develop an assay to test biofilm phenotype in a large array of food processing-related environmental conditions (salt, acides, disinfectants, preservatives) in BFC facilities. He will be in charge of the development and validation of an in silico virulence assay. This assay will target specific mRNAs in order to estimate the virulence potential of strains of L. monocytogenes. Transcript targets will be selected and tested by qPCR in GXP premises. In the process of validation, virulence results of several strains collected in a humanised mouse model will be compared with the in silico analysis. Once these innovative tools will be validated, intraspecific phenotypic diversity (biofilm and virulence) will be assessed on a collection of environmental and clinical isolates of L. monocytogenes. Genotypic diversity will be assessed under the supervision of GPX.
Expected Results : Adaptation of the BioFilm Ring test R to test food processing environmental conditions. Development of an innovative in silico virulence assay surrogate to animal models. Diversity results will inform stakeholders on the level of health hazard according to the strain. This in turn will help secure food safety all along the shelf life of foodstuff.
Duration (months) 36
Contact : Dr. Thierry BERNARDI: thbe@biofilmcontrol.com
Dr. Bjorn ROTTER: rotter@genxpro.de
ELIGIBLE CRITERIA of Marie Sklokowska Curie actions:
Researchers may be of any nationality
Candidates shall at the time of recruitment by the host organization, be in the first four years (full-time equivalent research experience) of their research careers. Full-time equivalent research experience is measured from the date when a researcher obtained the degree which would formally entitle him or her to embark on a doctorate, either in the co

GABi

Fri, 06 Dec 2013 16:43:01 -0600

GABi Research
The major researching fields defined as the GABi scope are described next:
Sequence Analysis
Protein Structure Prediction
Comparative Genomics
Functional Analysis of Residues on Protein Families
Gene/Protein Networks
Genome structure & base composition
Highthroughput data analysis from NGS

Lab Page http://gabi.cidbio.org/index/