Address of the bookmark: https://github.com/martinjvickers/KAST

Applications are invited along with complete bio-data and attested copies of certificates of qualifications, experience etc. for the one post of Research Fellow and one post of Program Assistant under PURSE Grant of the University in Centre for Systems Biology & Bioinformatics, UIEAST, Panjab University, Chandigarh which is tenable till the period of
the project.

Essential Qualification

For Research Fellow:-

M.Sc. in Systems Biology and Bioinformatics / Life Sciences with minimum 55% marks.

Preference will be given to NET/GATE/ICMR qualified candidates without fellowship however, candidates who have cleared the Panjab University Ph.D. entrance test in Systems Biology & Bioinformatics will also be eligible.

For Program Assistant:-

The candidate must have M.Sc./M.Tech/MCA/PGDCA in Computer Science and must be able to handle LAN, Linex. Preference will be given to the candidate having experience in
System Administration.

Emoluments

For Research Fellow Rs. 12,500/- per month (Fixed)
For Program Assistant Rs. 12,500/- per month (Fixed)

Applications should be reach on or before 19-11-2014 in the office of the undersigned.

Interview will be held on 21-11-2014 in the office of the Coordinator, Centre for Systems Biology & Bioinformatics, South Campus, Block-3, Sector-25, Panjab University, Chandigarh. No TA/DA will be paid.

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Address of the bookmark: https://github.com/sc932/ALE

Reference Number IIT/SRIC/R/DIC/2014/314, DATED 28thNovember, 2014

Temporary Position(s)

i) Junior/ Senior Project Officer (1)
ii) Junior Project Assistant (2)

Consolidated Compensation

i) Rs.16,000/- to Rs.18,000/- p.m. (depending on qualification & experience)
ii) Rs.8,000/- to Rs.10,000/- p.m. (depending on qualification & experience)

Coordinator / PI Dr. Sudip K. Ghosh, Dept of Biotechnology.

Department / Centre / School Dept of Biotechnology

Qualifications & Experience

(i) M. Sc in any branch of Life Sciences with experience in Molecular Biology/Genetics/Biochemistry preferably a Post Graduate diploma in Bioinformatics or two years working experience in bioinformatics (Minimum 60% marks starting from matriculation examination).

(ii) B. Sc. /B.A. /B. Com/Diploma in Management or Computer Science. Knowledge in computer software will be preferred (minimum 50% marks starting from matriculation examination).

More Information

Interested eligible persons may apply on plain paper, giving full bio-data along with attested copies of testimonials to the undersigned on or before 11thDecember, 2014.

Sponsor DBT, NEW DELHI

Last Date 11 Dec 2014

Application Fee Demand Draft for Rs.50/- (Not for female candidates) drawn in favour of IIT Kharagpur payable at Kharagpur

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To find repeats in a genome from 2 to 9 length using a Perl script, you can use the RepeatMasker tool with the "--length" option[0]. Here's a step-by-step guide:

Overview of SLiM and msprime

SLiM: Forward Genetic Simulator

SLiM is a free, open-source tool designed for forward genetic simulations. It allows researchers to model complex evolutionary scenarios, including selection, recombination, and demographic events, making it particularly useful for studying adaptation and selection in populations.

Key Features of SLiM:

• Simulates population evolution forward in time

• Supports custom evolutionary models using an embedded scripting language

• Allows modeling of spatial and ecological dynamics

• Provides high flexibility and extensibility for user-defined scenarios

• Available on GitHub as an open-source project

msprime: Ancestry and Mutation Simulator

msprime is an efficient, open-source tool that simulates ancestry and mutations using a coalescent framework. It is known for its high-speed performance and low memory requirements, making it a popular choice for large-scale genomic simulations.

Key Features of msprime:

• Implements coalescent simulations for ancestry modeling

• Efficiently simulates large population histories

• Supports the addition of mutations to genealogies

• Developed using an open-source community model

• Often faster and more memory-efficient than alternative simulators

Using SLiM and msprime with slendr

Both SLiM and msprime can be integrated with slendr, a framework that facilitates structured population genetic simulations. This integration allows for seamless comparison of simulation outputs.

How They Work Together:

• SLiM and msprime simulations can be analyzed within slendr.

• The ts_read() function in slendr enables loading and comparing tree sequence outputs from both simulators.

• This integration allows researchers to validate simulation results and gain deeper insights into evolutionary processes.

Performance Considerations

While SLiM offers powerful forward simulations with extensive customization, msprime is often preferred for its speed and memory efficiency when simulating ancestry and mutations. The choice between the two depends on the research goals:

• For detailed evolutionary modeling with selection and recombination: Use SLiM.

• For large-scale coalescent simulations with mutations: Use msprime.

• For comparing different simulation models and their outputs: Use slendr to integrate SLiM and msprime results.

Conclusion

SLiM and msprime are valuable tools for genome simulation, each serving distinct but complementary purposes in population genetics research. By leveraging the strengths of both simulators with slendr, researchers can conduct robust and efficient evolutionary simulations, enhancing our understanding of genetic diversity and adaptation.

For more information, check out the official GitHub repositories for SLiM and msprime, and explore the slendr framework for streamlined simulation workflow

Originally design to map the location of objects in a 10 km map IrishGrid includes:

• native support of the Irish Grid System (see http://www.osi.ie/)
• optimize for speed (there's as less as possible data to conversion)
• customized color functions

https://code.google.com/p/irishgrid/downloads/detail?name=irishgrid.pl

Address of the bookmark: https://code.google.com/p/irishgrid/

More information:

https://genome.ucsc.edu/ENCODE/pilot.html

Address of the bookmark: https://genome.ucsc.edu/ENCODE/