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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/27696?offset=820</link>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/44930/bioinformatics-the-bridge-between-curiosity-and-discovery</guid>
	<pubDate>Mon, 24 Nov 2025 05:16:49 -0600</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/44930/bioinformatics-the-bridge-between-curiosity-and-discovery</link>
	<title><![CDATA[Bioinformatics: The Bridge Between Curiosity and Discovery]]></title>
	<description><![CDATA[<p>In the sprawling universe of modern science, bioinformatics stands as one of the most transformative and empowering fields of our time. It is where biology meets computation, where data becomes meaning, and where curiosity becomes discovery. If you&rsquo;ve stepped into this world&mdash;or are considering it&mdash;here&rsquo;s your reminder: you&rsquo;re part of a revolution.</p><p><strong>Why Bioinformatics Matters More Than Ever</strong></p><p>Every day, our world generates massive amounts of biological data&mdash;from genome sequences to microbiome profiles to real-time pathogen surveillance. Hidden within these datasets are the answers to some of the greatest challenges humanity faces: emerging diseases, antimicrobial resistance, environmental stress, genetic disorders, sustainable agriculture, and more.</p><p>Bioinformatics isn&rsquo;t just a skill.<br />It&rsquo;s the language of the future of biology.</p><p>By mastering it, you give yourself the power to:</p><p>Decode genomes and understand life at its most fundamental level</p><p>Identify patterns no microscope could ever reveal</p><p>Predict disease outbreaks before they occur</p><p>Accelerate drug discovery with computational precision</p><p>Contribute to open-source tools that empower scientists worldwide</p><p>You don&rsquo;t just follow science&mdash;you drive it.</p><p><strong>Every Expert Was Once a Beginner</strong></p><p>Many newcomers feel intimidated. Command-line interfaces. R scripts. Python packages. Next-generation sequencing data. Complex machine learning models.</p><p>But here&rsquo;s the truth: every bioinformatician started exactly where you are now&mdash;curious, unsure, but excited.</p><p>No one writes perfect code on day one.</p><p>No one understands genomics pipelines immediately.</p><p>What makes you a bioinformatician is not perfection, but perseverance.</p><p>When your script throws a cryptic error&hellip;<br />When your data refuses to format&hellip;<br />When your pipeline runs for 6 hours only to crash&hellip;</p><p>Remember: this is part of the journey.<br />Every error teaches you. Every retry strengthens you. Every breakthrough energizes you.</p><p>Bioinformatics Is Not Just a Career&mdash;It&rsquo;s a Mindset</p><p>It&rsquo;s the mindset of:</p><p>Problem-solving.</p><p>Continuous learning.</p><p>Turning chaos into clarity.</p><p>Seeing what others can&rsquo;t.</p><p>Bioinformaticians are detectives of biological complexity. You sit at the intersection of innovation, using tools that can shape public health, medicine, agriculture, and ecology. Few fields give you such direct impact on the world.</p><p><strong>Your Contribution Matters</strong></p><p>As you work on your script, pipeline, genome, or model, remember:</p><p>Somewhere, your analysis might contribute to:</p><p>A new therapy</p><p>A faster diagnostic test</p><p>A better understanding of a pathogen</p><p>A more resilient crop</p><p>An open-source dataset that helps thousands</p><p>A discovery that rewrites textbooks</p><p>Your code may be small, but its ripple effect is powerful.</p><p>The Future Is Bioinformatics&mdash;And You Are Part of It</p><p>The world is shifting. Wet labs are integrating AI. Hospitals rely on genomic insights. Farmers use gene-level predictions. Governments monitor disease in real time. Students launch pipelines that become global tools.</p><p>This is a golden era&mdash;and you are not late.<br />You are exactly where you need to be.</p><p>Keep Pushing. Keep Learning. Keep Discovering.</p><p>Bioinformatics is a journey filled with challenges, but also with unmatched rewards.</p><p>So the next time you feel stuck, frustrated, or overwhelmed, remember:<br />You&rsquo;re building the science of tomorrow.</p><p>Be proud. Stay curious. Keep going.<br />Your work matters more than you think.</p>]]></description>
	<dc:creator>BioStar</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/5255/walk-in-interview-indian-agricultural-statistics-research-institute</guid>
  <pubDate>Wed, 02 Oct 2013 15:40:17 -0500</pubDate>
  <link></link>
  <title><![CDATA[Walk-in-Interview @ Indian Agricultural Statistics Research Institute]]></title>
  <description><![CDATA[
<p>Indian Agricultural Statistics Research Institute<br />Library Avenue, Pusa, New Delhi – 110012</p>

<p>Walk-in-Interview</p>

<p>Walk-in-interview will be held on October 5, 2013 at 10:00 A.M. at IASRI, New Delhi for a project “A New Distributed Computing Framework for Data Mining” funded by Department of Electronics and Information Technology, Government of India for the following posts. The appointment will be on contractual basis upto 14th October, 2015 or till the termination of the project whichever is earlier and the incumbent shall not have any claim for regular appointment under ICAR.</p>

<p>Research Associate</p>

<p>    Ph.D. in Bioinformatics/ Agricultural Statistics/ Statistics/ Computer Science/ Computer Application or equivalent or</p>

<p>    Post-Graduation in Bioinformatics/ Agricultural Statistics/ Statistics/ Computer Science/ Computer Application or equivalent with 1st Division and at least two years of research experience</p>

<p>     Knowledge of Statistical Analysis /Bioinformatics tools for computational genomics.</p>

<p>     Knowledge of R/Perl programming language</p>

<p>Research Associate</p>

<p>    Ph.D. in Computer Science/ Computer Application / Bioinformatics/ Agricultural<br />    Statistics/ Statistics or equivalent or</p>

<p>    Post-Graduation in Computer Science/ Computer Application /Bioinformatics/ Agricultural Statistics/ Statistics or equivalent with 1st Division and at least two years of research experience</p>

<p>     Expertise in Java programming.<br />     Knowledge of system administration and networking under Linux environment.<br />     Knowledge of parallel programming and cluster computing.</p>

<p>Emoluments for Research Associate: Consolidated Rs:24000/- per month + HRA (for Ph.D. Degree holders) and Rs:23000/- per month + HRA (for Master’s Degree holders)</p>

<p>Age Limit: Age should be not more than 40 years (5 years relaxation for  SC/ST/women candidates and 3 years for OBC candidates as on date of interview).</p>

<p>Interested candidates are requested to appear for Walk-in-Interview on the date and time as specified above in Room No. 106, Training Cum Administrative Block of the Institute along with their application giving bio-data with attested copies of certificates, degrees, testimonials, etc. and one passport size photograph.</p>

<p>Original certificates/ Degrees are needed to be produced at the time of interview.</p>

<p>No T.A. /D.A. will be paid for appearing in the interview.</p>

<p>Advertisement: http://www.iasri.res.in/employment/employment.htm</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/view/1926</guid>
	<pubDate>Sun, 11 Aug 2013 11:42:32 -0500</pubDate>
	<link>https://bioinformaticsonline.com/view/1926</link>
	<title><![CDATA[Want to Know which genome assembler rule the world ?]]></title>
	<description><![CDATA[<p><span><strong>Assemblathon 2</strong>: evaluating de novo methods of genome assembly&nbsp;</span></p><p><span><a href="http://www.gigasciencejournal.com/content/2/1/10/abstract">http://www.gigasciencejournal.com/content/2/1/10/abstract</a></span></p><p><span><a href="http://blogs.nature.com/news/2013/07/genome-assembly-contest-prompts-soul-searching.html">http://blogs.nature.com/news/2013/07/genome-assembly-contest-prompts-soul-searching.html</a></span></p><p><a href="http://assemblathon.org/post/44431915644/feedback-and-analysis-of-the-assemblathon-2-p">http://assemblathon.org/post/44431915644/feedback-and-analysis-of-the-assemblathon-2-p</a></p><p>&nbsp;</p>]]></description>
	<dc:creator>Rahul Agarwal</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/5422/shendure-lab</guid>
  <pubDate>Wed, 09 Oct 2013 14:21:58 -0500</pubDate>
  <link></link>
  <title><![CDATA[Shendure Lab]]></title>
  <description><![CDATA[
<p>The Shendure Lab is part of the Department of Genome Sciences at the University of Washington (Seattle, WA). The mission of the lab is to develop and apply new technologies in genomics and molecular biology. Most projects in the lab exploit new DNA sequencing technologies (Shendure et al., Nature Reviews Genetics 2004; Shendure &amp; Ji, Nature Biotechnology 2008; Shendure &amp; Lieberman Aiden, Nature Biotechnology 2012), and generally fall into one of six areas: 1) next-generation human genetics; 2) genome contiguity &amp; completeness; 3) massively parallel functional analysis; 4) molecular tagging; 5) synthetic biology; 6) translational genomics. Our interests in each of these areas are outlined briefly below, and a full list of publications is available via PubMed. http://www.ncbi.nlm.nih.gov/pubmed?cmd=search&amp;term=shendure<br />More http://krishna.gs.washington.edu/research.html</p>

<p>Lab page @ http://krishna.gs.washington.edu/index.html</p>
]]></description>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/5661/shankar-lab</guid>
  <pubDate>Wed, 16 Oct 2013 07:02:22 -0500</pubDate>
  <link></link>
  <title><![CDATA[Shankar Lab]]></title>
  <description><![CDATA[
<p>Research Interest:</p>

<p>(A) Regulatory System Analysis with respect to microRNAs</p>

<p>(B) Computational Epigenomics &amp; Regulomics:</p>

<p>(C) Computational issues with Next Generation Sequencing:</p>

<p>Department of Biotechnology, <br />Institute of Himalyan Bioresources Technology<br />CSIR, Palampur(Himachal Pradesh), India.<br />Email: ravishihbt.res.in; ravish9gmail.com</p>

<p>More @ http://scbb.ihbt.res.in/SCBB_dept/Lab_Member.php</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/videolist/watch/4762/how-dna-is-packaged-advanced</guid>
	<pubDate>Mon, 23 Sep 2013 18:08:34 -0500</pubDate>
	<link>https://bioinformaticsonline.com/videolist/watch/4762/how-dna-is-packaged-advanced</link>
	<title><![CDATA[How DNA is Packaged (Advanced)]]></title>
	<description><![CDATA[<iframe width="" height="" src="https://www.youtube-nocookie.com/embed/gbSIBhFwQ4s" frameborder="0" allowfullscreen></iframe>Each chromosome consists of one continuous thread-like molecule of DNA coiled tightly around proteins, and contains a portion of the 6,400,000,000 basepairs (DNA building blocks) that make up your DNA. 
Originally created for DNA Interactive ( http://www.dnai.org ).
TRANSCRIPT: In this animation we'll see the remarkable way our DNA is tightly packed up to fit into the nucleus of every cell. The process starts with assembly of a nucleosome, which is formed when eight separate histone protein subunits attach to the DNA molecule. The combined tight loop of DNA and protein is the nucleosome. Six nucleosomes are coiled together and these then stack on top of each other. The end result is a fiber of packed nucleosomes known as chromatin. This structure, is then looped and further packaged using other proteins (which are not shown here) to give the final "chromosomal" shapes. It is this remarkable multiple folding which allows six feet of DNA to fit into the nucleus of each cell in our body. And a typical cell nucleus is so small that ten thousand could fit on the tip of a needle. It is important to realize that chromosomes are not always present, they form only when cells are dividing. At other times, as we can see here at the end of cell division, our DNA becomes less highly organized.)]]></description>
	
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/5747/dbbrowser-attwood-lab</guid>
  <pubDate>Fri, 18 Oct 2013 10:48:19 -0500</pubDate>
  <link></link>
  <title><![CDATA[DbBrowser: Attwood Lab]]></title>
  <description><![CDATA[
<p>DbBrowser: Attwood Lab research concerns protein sequence analysis, primarily using the method of protein 'fingerprinting'. DbBrowser: Attwood Lab maintain a diagnostic fingerprint database (PRINTS), one of the founding partner of InterPro. We also design software to display sequence and structural data in visually-striking ways (e.g., Ambrosia, CINEMA); DbBrowser: Attwood Lab are building re-usable software components to create semantically integrated bioinformatics applications through UTOPIA, including a 'smart' PDF reader that links bioinformatics databases and tools directly with scientific articles (Utopia Documents); and have developed a number of tools for automatic annotation and text mining (e.g., MINOTAUR, PRECIS, METIS). </p>

<p>More @ http://www.bioinf.manchester.ac.uk/dbbrowser/index.php</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/42965/nucl2vec-local-alignment-of-dna-sequences-using-distributed-vector-representation</guid>
	<pubDate>Tue, 16 Mar 2021 05:45:44 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/42965/nucl2vec-local-alignment-of-dna-sequences-using-distributed-vector-representation</link>
	<title><![CDATA[Nucl2Vec: Local alignment of DNA sequences using Distributed Vector Representation]]></title>
	<description><![CDATA[<p><span>We demonstrate a novel approach for</span><span>local alignment of DNA reads with respect to reference genome.</span><span>For this process we have used Skip-gram model for creating</span><span>encoding(Nucl2Vec) and k-nearest neighbor for the alignment.</span><span>With our new approach we have reduced computation cost for</span><span>local alignment , while achieving accuracy comparable to existing</span><span>defacto standard BWA-MEM tool.</span> </p>
<p><em>https://prakharg24.github.io/papers/401851.full.pdf</em></p><p>Address of the bookmark: <a href="https://prakharg24.github.io/papers/401851.full.pdf" rel="nofollow">https://prakharg24.github.io/papers/401851.full.pdf</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/5946/bioinformatics-tata-memorial-centre-navi-mumbai</guid>
  <pubDate>Mon, 28 Oct 2013 10:40:25 -0500</pubDate>
  <link></link>
  <title><![CDATA[Bioinformatics @ TATA MEMORIAL CENTRE, NAVI MUMBAI]]></title>
  <description><![CDATA[
<p>TATA MEMORIAL CENTRE<br />ADVANCED CENTRE FOR TREATMENT, RESEARCH AND EDUCATION IN CANCER<br />KHARGHAR, NAVI MUMBAI – 410210</p>

<p>No. ACTREC/Advt./ 72 /2013</p>

<p>WALK IN INTERVIEW</p>

<p>1. JRF*<br />Genome-wide RNAi screen with human pooled tyrosine kinase shRNA libraries in head and neck squamous call carcinoma (HNSCC) cell lines<br />DBT A/C No. 3071, Dr. Amit Dutt</p>

<p>2. JRF<br />IRB Project ACTREC Funds<br />Dr. Amit Dutt</p>

<p>3. RA<br />Defining the cancer genome of Head and Neck Squamous Cell Carcinoma (HNSCC) with SNP arrays and next generation sequencing technology<br />A/C No. 2895, Dr. Amit Dutt</p>

<p>Duration of the Project: One year from the date of appointment, or as and when project terminates.</p>

<p>Consolidated Salary: RA : Rs. 40,000/- p.m.<br />JRF* (DBT): Rs. 20,800/- p.m.<br />JRF: Rs. 16,000/- p.m.<br />Date &amp; Time: 6th November, 2013, at 10.00 a.m.</p>

<p>Venue: Conference Room</p>

<p>Minimum Qualifications and Experience:</p>

<p>RA: The ideal applicant should have a PhD in a relevant field. He/she should have a strong computational biology background, with demonstrated experience in coding using Perl, Python, Java or C++. He/she should be familiar with working in unix enviromnent, devising computational algorithms for data analysis, statistical data analysis in R and matlab and database programming using MySQL. Hands on experience in analyzing high throughput data would be an added advantage.</p>

<p>JRF* (DBT project): M.Sc. in Life Sciences or M.Tech in Biotechnology with good academic record (Minimum of 60% aggregate). Valid UGC-CSIR/DBT/ICMR JRF qualification and laboratory experience in molecular biology. Previous experience in molecular biology and animal tissue culture with high throughput platforms and ability to work with a large team would be desirable.</p>

<p>JRF (ACTREC project): M.Sc. in Life Sciences or M.Tech in Biotechnology with good academic record (Minimum of 60% aggregate). Minimum 2 yrs experience in molecular biology and animal tissue culture with high throughput platforms and ability to work with a large team is essential.</p>

<p>*M.Sc. degree obtained after a one year course will not be considered.</p>

<p>Candidates fulfilling above requirements should send their application by e-mail to<br />‘careers.duttlab@gmail.com. in the format given below so as to reach on or before<br />4th November, 2013.</p>

<p>Advertisement:</p>

<p>http://www.actrec.gov.in/data%20files/2013/AD-RA-JR-TECHN-6-NOV.pdf</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/34386/slidesort-bpr</guid>
	<pubDate>Mon, 20 Nov 2017 09:19:52 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/34386/slidesort-bpr</link>
	<title><![CDATA[SLIDESORT-BPR]]></title>
	<description><![CDATA[<p>Chromosomal rearrangement events are caused by abnormal breaking and rejoining of DNA molecules. They are responsible for many of the cancer related diseases. Detecting the DNA breaking and repairing mechanism, therefore, may offer vital clues about the pathologic causes and diagnostic/therapeutic target of these diseases. But this effort also poses considerable challenges, because the structural variations and the genomes are different from one person to another. Intermediate comparison via reference genome could lead to the loss information. Unlike the current methods which make use the reference genome, we developed a method to detect the breakpoint reads directly from observing the differences between two (or more) NGS short reads samples. Slidesort-BPR is a command line tool implemented in C++.</p><p>Address of the bookmark: <a href="https://github.com/ewijaya/slidesort-bpr" rel="nofollow">https://github.com/ewijaya/slidesort-bpr</a></p>]]></description>
	<dc:creator>Abhimanyu Singh</dc:creator>
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