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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/27818?offset=1290</link>
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	<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/43926/aun-a-new-metric-to-measure-assembly-contiguity</guid>
	<pubDate>Tue, 02 Aug 2022 01:18:47 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/43926/aun-a-new-metric-to-measure-assembly-contiguity</link>
	<title><![CDATA[auN: a new metric to measure assembly contiguity]]></title>
	<description><![CDATA[<p><span>Given a de novo assembly, we often measure the &ldquo;average&rdquo; contig length by N50.&nbsp;</span><a href="https://en.wikipedia.org/wiki/N50,_L50,_and_related_statistics">N50</a><span>&nbsp;is neither the real average nor median. It is the length of the contig such that this and longer contigs cover at least 50% of the assembly. A longer N50 indicates better contiguity. We can similarly define N</span><em>x</em><span>&nbsp;such that contigs no shorter than N</span><em>x</em><span>&nbsp;covers&nbsp;</span><em>x</em><span>% of the assembly. The N</span><em>x</em><span>&nbsp;curve plots N</span><em>x</em><span>&nbsp;as a function of&nbsp;</span><em>x</em><span>, where&nbsp;</span><em>x</em><span>&nbsp;is ranged from 0 to 100.</span></p>
<p><span><img src="http://lh3.github.io/images/NGx_plot.png" alt="image" style="border: 0px;"></span></p><p>Address of the bookmark: <a href="https://lh3.github.io/2020/04/08/a-new-metric-on-assembly-contiguity" rel="nofollow">https://lh3.github.io/2020/04/08/a-new-metric-on-assembly-contiguity</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/pages/view/44377/mitochondrial-genome-assembly-tools</guid>
	<pubDate>Wed, 06 Sep 2023 00:37:18 -0500</pubDate>
	<link>https://bioinformaticsonline.com/pages/view/44377/mitochondrial-genome-assembly-tools</link>
	<title><![CDATA[Mitochondrial genome assembly tools !]]></title>
	<description><![CDATA[<p>Mitochondrial genome assembly tools are specialized software and algorithms designed to accurately reconstruct the mitochondrial genome (mitogenome) from sequencing data, typically obtained through techniques like next-generation sequencing (NGS). The mitochondrial genome is relatively small compared to the nuclear genome, making it an ideal target for assembly. Here are some commonly used mitochondrial genome assembly tools:</p><p><strong>MitoFinder:</strong> Mitofinder is a pipeline to assemble mitochondrial genomes and annotate mitochondrial genes from trimmed read sequencing data.</p><p><strong>MitoHiFi:</strong> a python pipeline for mitochondrial genome assembly from PacBio high fidelity reads</p><p>MITObim: MITObim is a tool specifically developed for the iterative assembly of mitochondrial genomes. It starts with a reference mitogenome and iteratively refines the assembly using the read data.</p><p><strong>MITOS:</strong> MITOS is a web-based platform that provides a pipeline for annotating mitochondrial genomes. It integrates multiple software tools for assembly, annotation, and visualization of mitogenomes.</p><p><strong>MIRA:</strong> MIRA (Mimicking Intelligent Read Assembly) is a versatile genome assembly tool that can be used for mitochondrial genome assembly. It supports various sequencing technologies and allows for reference-based or de novo assembly.</p><p><strong>NOVOPlasty:</strong> NOVOPlasty is a user-friendly tool designed for de novo assembly of organelle genomes, including mitochondria. It utilizes a seed-and-extend algorithm and is suitable for both short-read and long-read data.</p><p><strong>MITOS2:</strong> MITOS2 is an updated version of the MITOS pipeline, which automates the annotation of mitochondrial genomes. It provides improved accuracy and additional features for mitochondrial genome analysis.</p><p><strong>GetOrganelle:</strong> While primarily designed for chloroplast genome assembly, GetOrganelle can also be used for mitochondrial genome assembly. It is particularly useful for dealing with high-throughput sequencing data.</p><p><strong>SPAdes:</strong> SPAdes (St. Petersburg genome assembler) is a versatile genome assembly tool that can be employed for mitochondrial genome assembly, especially when dealing with complex datasets that may contain nuclear mitochondrial DNA sequences (numts).</p><p><strong>IDBA-UD:</strong> IDBA-UD (Iterative De Bruijn Graph De Novo Assembler) is another de novo assembly tool that can be used for mitochondrial genome assembly, especially in cases with relatively low coverage.</p><p><strong>Velvet:</strong> Velvet is a de novo assembly tool that can be applied to mitochondrial genome assembly, especially when working with short-read data.</p><p>When selecting a mitochondrial genome assembly tool, it's important to consider the specific characteristics of your sequencing data, such as read length and coverage, as well as the complexity of the mitochondrial genome. Additionally, some tools are better suited for specific organisms or research objectives, so choosing the right tool will depend on your particular project requirements.</p>]]></description>
	<dc:creator>Abhi</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/30168/gene-synteny-database</guid>
	<pubDate>Fri, 16 Dec 2016 11:09:39 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/30168/gene-synteny-database</link>
	<title><![CDATA[Gene Synteny Database]]></title>
	<description><![CDATA[<p>Comparative genomics remains a pivotal strategy to study the evolution of gene organization, and this primacy is reinforced by the growing number of full genome sequences available in public repositories. Despite this growth, bioinformatic tools available to visualize and compare genomes and to infer evolutionary events remain restricted to two or three genomes at a time, thus limiting the breadth and the nature of the question that can be investigated. Here we present Genomicus, a new synteny browser that can represent and compare unlimited numbers of genomes in a broad phylogenetic view. In addition, Genomicus includes reconstructed ancestral gene organization, thus greatly facilitating the interpretation of the data.</p>
<p><strong>Availability:</strong>&nbsp;Genomicus is freely available for online use at&nbsp;<a href="http://www.dyogen.ens.fr/genomicus" target="pmc_ext">http://www.dyogen.ens.fr/genomicus</a>&nbsp;while data can be downloaded at&nbsp;<a href="ftp://ftp.biologie.ens.fr/pub/dyogen/genomicus" target="pmc_ext">ftp://ftp.biologie.ens.fr/pub/dyogen/genomicus</a></p>
<p><strong>Contact:</strong>&nbsp;<a href="mailto:dev@null">rf.sne.eigoloib@crh</a></p><p>Address of the bookmark: <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853686/" rel="nofollow">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853686/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/30355/meme-suite</guid>
	<pubDate>Fri, 23 Dec 2016 08:49:55 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/30355/meme-suite</link>
	<title><![CDATA[MEME suite]]></title>
	<description><![CDATA[<p>Motif based sequence analysis suits&nbsp;</p>
<p>The MEME Suite allows the biologist to discover novel motifs in collections of unaligned nucleotide or protein sequences, and to perform a wide variety of other motif-based analyses.</p>
<p>The MEME Suite supports motif-based analysis of DNA, RNA and protein sequences. It provides motif discovery algorithms using both probabilistic (MEME) and discrete models (MEME), which have complementary strengths. It also allows discovery of motifs with arbitrary insertions and deletions (GLAM2). In addition to motif discovery, the MEME Suite provides tools for scanning sequences for matches to motifs (FIMO, MAST and GLAM2Scan), scanning for clusters of motifs (MCAST), comparing motifs to known motifs (Tomtom), finding preferred spacings between motifs (SpaMo), predicting the biological roles of motifs (GOMo), measuring the positional enrichment of sequences for known motifs (CentriMo), and analyzing ChIP-seq and other large datasets (MEME-ChIP).</p>
<p>The MEME Suite is comprised of a collection of tools that work together, as shown below. Not all the tools are available as webservices, so to get the full power of the MEME Suite you will need to&nbsp;<a href="http://meme-suite.org/doc/download.html">download</a>&nbsp;and&nbsp;<a href="http://meme-suite.org/doc/install.html">install</a>&nbsp;a local copy of the software. To see what has changed recently you can peruse the&nbsp;<a href="http://meme-suite.org/doc/release-notes.html">release notes</a>.</p>
<p>http://meme-suite.org/</p><p>Address of the bookmark: <a href="http://meme-suite.org/" rel="nofollow">http://meme-suite.org/</a></p>]]></description>
	<dc:creator>Bulbul</dc:creator>
</item>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/30744/binc-2017</guid>
	<pubDate>Wed, 01 Feb 2017 09:36:22 -0600</pubDate>
	<link>https://bioinformaticsonline.com/news/view/30744/binc-2017</link>
	<title><![CDATA[BINC 2017]]></title>
	<description><![CDATA[<p><span>Pondicherry University,Puducherry,on behalf of Department of Biotechnology, Government of India, conducted the BINC examination in&nbsp;</span><span style="color: blue;">2015 and 2016.&nbsp;</span><span>The objective of this examination is to certify bioinformatics professionals, trained formally as well as self-trained.</span><span style="color: blue;">Registration for BINC 2017 examination will open from January 29,2017 to February 28,2017.</span><span>&nbsp;</span></p><p><span>Pondicherry University, Puducherry has been identified as a nodal agency by the Department of Biotechnology, Govt. of India to coordinate this examination along with nine centres namely, </span></p><p><span>Pune University, Pune; </span></p><p><span>Anna University, Chennai; </span></p><p><span>Bose Institute, Kolkata; </span></p><p><span>Institute of Bioinformatics &amp; Applied Biotechnology, Bangalore; </span></p><p><span>North-Eastern Hill University, Shillong, University of Hyderabad, Hyderabad; </span></p><p><span>University of Kerala, Thiruvananthapuram; </span></p><p><span>Jawaharlal Nehru University, New Delhi and </span></p><p><span>Assam Agricultural University, Guwahati.</span><span style="color: blue;"><strong>&nbsp;</strong></span></p><p><span style="color: blue;"><strong>In the BINC 2015 and 2016 examination, 23 candidates and five candidates were certified respectively.</strong></span><span>&nbsp;DBT has agreed to fund Research fellowships for all the BINC qualified Indian nationals to pursue Ph.D. in Indian Institutes/Universities. </span></p><p><span>Note that the candidate must possess a postgraduate degree(or equivalent) &amp; meet the criteria of the institutes/universities in order to avail research fellowship. </span></p><p><span>In addition, cash prize of Rs. 10,000/- will be awarded to the top 10 BINC qualifiers.</span></p><p><span>More at&nbsp;http://www.pondiuni.edu.in/exams/binc/</span></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/30901/ideoplot</guid>
	<pubDate>Mon, 13 Feb 2017 09:47:32 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/30901/ideoplot</link>
	<title><![CDATA[Ideoplot]]></title>
	<description><![CDATA[<p>Simple ideogram plotting and annotation in R.</p>
<p>Basic usage:</p>
<p>Rscript Ideoplot.R --heatmap hm.bed --annotate annotations.bed --out ideogram.pdf<br> -or-<br> Rscript Ideoplot.R --annotate annotations.bed</p>
<pre>Options
  --ideobed, i      A bed file of reference contig lengths/chromosome names
  --heatmap, -h     Fill chromosomes with normalized heatmap
                   (described below)
  --annotate, -a    Add character annotations.
  --out, -o         PDF output name.
  --stripes, -s     Specify a file containing the layout of the
                    annotations (description below)
  --bars, -b        Add track annotations
  --reference, -f   Either hg19, or hg38
  --topdown, r      Flag, when set, flips the orientation (P arms
                    drawn on top).
</pre><p>Address of the bookmark: <a href="https://github.com/mchaisso/Ideoplot" rel="nofollow">https://github.com/mchaisso/Ideoplot</a></p>]]></description>
	<dc:creator>Shruti Paniwala</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/31207/laj-viewing-and-manipulating-the-output-from-pairwise-alignment-programs</guid>
	<pubDate>Wed, 01 Mar 2017 08:35:40 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/31207/laj-viewing-and-manipulating-the-output-from-pairwise-alignment-programs</link>
	<title><![CDATA[Laj: viewing and manipulating the output from pairwise alignment programs]]></title>
	<description><![CDATA[<p>Laj is a tool for viewing and manipulating the output from pairwise alignment programs such as <a href="http://bio.cse.psu.edu/">blastz</a>. It can display interactive dotplot, pip, and text representations of the alignments, a diagram showing the locations of exons and repeats, and annotation links to other web sites containing additional information about particular regions.</p>
<p>The program is written in Java in order to provide a graphical user interface that is portable across a variety of computer platforms; indeed its name stands for "Local Alignments with Java". Currently it exists in two forms, a stand-alone application and a web-based applet, with slightly different capabilities.</p><p>Address of the bookmark: <a href="http://www.bx.psu.edu/~ratan/" rel="nofollow">http://www.bx.psu.edu/~ratan/</a></p>]]></description>
	<dc:creator>Abhimanyu Singh</dc:creator>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/31251/bioinformatics-opening-at-icgeb-new-delhi</guid>
  <pubDate>Thu, 02 Mar 2017 04:16:36 -0600</pubDate>
  <link></link>
  <title><![CDATA[Bioinformatics opening at ICGEB NEW DELHI]]></title>
  <description><![CDATA[
<p>ICGEB NEW DELHI</p>

<p>Applications are invited for:</p>

<p>Junior Research Fellow, in a DBT funded project, is available in Translational Health Group, ICGEB, New Delhi</p>

<p>Qualifications:</p>

<p>Education: M.Sc. (preferably in Biotechnology, Life Sciences or Zoology, Chemistry, Bioinformatics). Candidates with hands on experience on GC-MS data acquisition and analysis will be given preference. Bioinformatics expertise required.</p>

<p>Fellowship: As per DBT guidelines.</p>

<p>Tenure: The position is purely on temporary basis with an initial tenure of six months and based on satisfactory performance may continue until the completion of the project.</p>

<p>Closing date for applications: 04/03/2017</p>

<p>Please send a "TWO PAGE" CV by email to:  th.icgeb@gmail.com on or before the last date.</p>

<p>Research Associate, in a DBT funded project, is available in Translational Health Group, ICGEB, New Delhi</p>

<p>Qualifications:</p>

<p>Education: Ph.D. (in Biology, Biotechnology, Chemistry, Bioinformatics). Candidates with hands on experience on GC-MS data acquisition and analysis will be given preference. </p>

<p>Fellowship: As per DBT guidelines.</p>

<p>Tenure: The position is purely on temporary basis with an initial tenure of six months and  based on satisfactory performance may continue until the completion of the project.</p>

<p>Closing date for applications: 04/03/2017</p>

<p>Please send a "TWO PAGE" CV by email to: th.icgeb@gmail.com on or before the last date.</p>
]]></description>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/31526/sequenceserver</guid>
	<pubDate>Fri, 10 Mar 2017 08:51:55 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/31526/sequenceserver</link>
	<title><![CDATA[sequenceserver]]></title>
	<description><![CDATA[<p><span>SequenceServer lets you rapidly set up a BLAST+ server with an intuitive user interface for use locally or over the web.</span></p>
<p><span><span>More at&nbsp;</span><a href="http://sequenceserver.com/">http://sequenceserver.com</a><span>.</span></span></p><p>Address of the bookmark: <a href="https://github.com/wurmlab/sequenceserver" rel="nofollow">https://github.com/wurmlab/sequenceserver</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/32018/tmap-torrent-mapping-alignment-program-general-notes</guid>
	<pubDate>Sun, 02 Apr 2017 15:53:47 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/32018/tmap-torrent-mapping-alignment-program-general-notes</link>
	<title><![CDATA[TMAP - torrent mapping alignment program General Notes]]></title>
	<description><![CDATA[<p>TMAP - torrent mapping alignment program <a href="https://github.com/iontorrent/TS/tree/master/Analysis/TMAP#general-notes"></a>General Notes</p>
<p>TMAP is a fast and accurate alignment software for short and long nucleotide sequences produced by next-generation sequencing technologies.</p>
<ul>
<li>
<p>The latest TMAP is unsupported. To use a supported version, please see the TMAP version associated with a Torrent Suite release below.</p>
</li>
<li>
<p>Get the latest source code:</p>
<div>
<pre>git clone git://github.com/iontorrent/TMAP.git
 <span>cd</span> TMAP
 git submodule init
 git submodule update</pre>
</div>
</li>
</ul>
<p>https://github.com/iontorrent/TS/tree/master/Analysis/TMAP</p><p>Address of the bookmark: <a href="https://github.com/iontorrent/TS/tree/master/Analysis/TMAP" rel="nofollow">https://github.com/iontorrent/TS/tree/master/Analysis/TMAP</a></p>]]></description>
	<dc:creator>Poonam Mahapatra</dc:creator>
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