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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/27845?offset=1130</link>
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	<description><![CDATA[]]></description>
	
	
<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/27240/bioinformatics-tutor-at-pgimer</guid>
  <pubDate>Wed, 04 May 2016 08:40:26 -0500</pubDate>
  <link></link>
  <title><![CDATA[Bioinformatics Tutor at PGIMER]]></title>
  <description><![CDATA[
<p>Postgraduate Institute of Medical Education and Research (PGIMER) - Chandigarh, Chandigarh<br />₹9,300 - ₹34,800 a month<br />Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh invites Online Applications for recruitment of following Group 'A', 'B' and 'C' posts. The closing date for submission of online applications is up to 12th May 2016.</p>

<p>No of Vacancies: 01<br />Pay Scale: Rs. 9300-34800 + Grade Pay Rs. 4600/-</p>

<p>Educational Qualification and Experience: (From Recognized University / Institute) M.Sc. in Biotechnology, Molecular Biology, Human Genomics / Biochemistry / Biophysics.</p>

<p>Age Limit: 18-50 years</p>

<p>Please see Detailed Advertisement Link for full info: https://drive.google.com/file/d/0Bz3xO6e_7OeeZllINnRyWlN5UFE/view</p>
]]></description>
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<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/27291/summer-internship-positions-at-dupont</guid>
  <pubDate>Wed, 11 May 2016 08:05:54 -0500</pubDate>
  <link></link>
  <title><![CDATA[Summer internship positions at DuPont]]></title>
  <description><![CDATA[
<p>DuPont Industrial Biosciences has several summer internship positions<br />for undergrads available. We are looking for driven and creative interns<br />to conduct research in the following areas:</p>

<p>· Enzyme immobilization supports for select enzyme systems.</p>

<p>· New tools for microbial strain and genome engineering using<br />state-of-the-art methodologies.</p>

<p>· Rapid high throughput assays to screen microorganisms from various<br />sources for enzymatic activities of interest.</p>

<p>· High throughput combinatorial approaches to the formulation of growth<br />media in support of microbial enrichments, strain isolations and growth<br />optimization.</p>

<p>· Meta-transcriptomics for the discovery of new enzymes.</p>

<p>· Strain adaptation techniques in defined chemostat environments for<br />microbial strain development.</p>

<p>The internships are based at the Experimental Station R&amp;D Center in<br />Wilmington, DE.</p>

<p>If interested, apply fast!</p>

<p>For more information and to apply, go to:</p>

<p>http://careers.dupont.com/jobsearch/job-details/industrial-biosciences-summer-internship/008549W-10/</p>
]]></description>
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<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/pages/view/27321/slurm-basics</guid>
	<pubDate>Fri, 13 May 2016 04:42:24 -0500</pubDate>
	<link>https://bioinformaticsonline.com/pages/view/27321/slurm-basics</link>
	<title><![CDATA[SLURM basics !]]></title>
	<description><![CDATA[<p><a href="http://bioinformaticsonline.com/bookmarks/view/27238/slurm" target="_blank">SLURM</a> is a queue management system and stands for Simple Linux Utility for Resource Management. SLURM was developed at the Lawrence Livermore National Lab and currently runs some of the largest compute clusters in the world.</p><p>SLURM is similar in many ways to most other queue systems. You write a batch script then submit it to the queue manager. The queue manager then schedules your job to run on the queue (or partition in SLURM parlance) that you designate. Below we will provide an outline of how to submit jobs to SLURM, how SLURM decides when to schedule your job and how to monitor progress.</p><p>SLURM has a number of valuable features compared to other job management systems:</p><ul>
<li><em>Kill and Requeue</em> SLURM&rsquo;s ability to kill and requeue is superior to that of other systems. It waits for jobs to be cleared before scheduling the high priority job. It also does kill and requeue on memory rather than just on core count.</li>
<li><em>Memory</em> Memory requests are sacrosanct in SLURM. Thus the amount of memory you request at run time is guaranteed to be there. No one can infringe on that memory space and you cannot exceed the amount of memory that you request.</li>
<li><em>Accounting Tools</em> SLURM has a back end database which stores historical information about the cluster. This information can be queried by the users who are curious about how much resources they have used.</li>
</ul><p><strong>Summary of SLURM commands</strong></p><p>The table below shows a summary of SLURM commands. These commands are described in more detail below along with links to the SLURM doc site.</p><table>
<tbody>
<tr><th>&nbsp;</th><th>SLURM</th><th>SLURM Example</th></tr>
<tr>
<td>Submit a batch serial job</td>
<td><a href="http://slurm.schedmd.com/sbatch.html">sbatch</a></td>
<td><code>sbatch runscript.sh</code></td>
</tr>
<tr>
<td>Run a script interatively</td>
<td><a href="http://slurm.schedmd.com/srun.html">srun</a></td>
<td><code>srun --pty -p interact -t 10 --mem 1000 /bin/bash /bin/hostname</code></td>
</tr>
<tr>
<td>Kill a job</td>
<td><a href="http://slurm.schedmd.com/scancel.html">scancel</a></td>
<td><code>scancel 999999</code></td>
</tr>
<tr>
<td>View status of queues</td>
<td><a href="http://slurm.schedmd.com/squeue.html">squeue</a></td>
<td><code>squeue -u akitzmiller</code></td>
</tr>
<tr>
<td>Check current job by id</td>
<td><a href="http://slurm.schedmd.com/squeue.html">sacct</a></td>
<td><code>sacct -j 999999</code></td>
</tr>
</tbody>
</table>]]></description>
	<dc:creator>Radha Agarkar</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/27461/maftools</guid>
	<pubDate>Sat, 21 May 2016 22:40:21 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/27461/maftools</link>
	<title><![CDATA[mafTools]]></title>
	<description><![CDATA[<p><span>Bioinformatics tools for dealing with Multiple Alignment Format (MAF) files.</span></p><p>Address of the bookmark: <a href="https://github.com/dentearl/mafTools" rel="nofollow">https://github.com/dentearl/mafTools</a></p>]]></description>
	<dc:creator>Radha Agarkar</dc:creator>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/27473/project-assistantjunior-research-fellow-position-at-centre-of-biomedical-research-sanjay-gandhi-postgraduate-institute-of-medical-sciences-campus-lucknow</guid>
  <pubDate>Mon, 23 May 2016 01:31:29 -0500</pubDate>
  <link></link>
  <title><![CDATA[Project Assistant/Junior Research Fellow Position at  Centre of Biomedical Research, Sanjay Gandhi Postgraduate Institute of Medical Sciences Campus, Lucknow.]]></title>
  <description><![CDATA[
<p>Applications are invited from eligible candidates willing to join in a Department of Science and Technology (DST) project entitled “"Mapping neural regions involved in reading process in skilled adult Deaf reader: From neuroimaging perspective (functional Magnetic Resonance Imaging (fMRI) and Diffuse Tensor Imaging (DTI.)" as a Project Assistant/Junior Research Fellow (JRF) at Centre of Biomedical Research, Sanjay Gandhi Postgraduate Institute of Medical Sciences Campus, Lucknow.</p>

<p>Essential Qualification:</p>

<p>1. Master's degree in Bioinformatics / Computer Applications / Cognitive Science /Neuroscience/ Neuropsychology or equivalent. (Advantage will be given to NET JRF qualified candidate) Additional</p>

<p>Desirable Skills:</p>

<p>1) Programming skills (e.g., C++, Matlab, Python) 2) Experience/competent in working Window and Linux based programme.</p>

<p>Please mail your CV and covering letter to dr.uttam.kumar@gmail.com.</p>

<p>To know more about lab works please visit http://uttambrainlab.co.in/lab/.</p>

<p>Last date: 15/06/16</p>

<p>Advertisement: http://cbmr.res.in/wp-content/uploads/2016/05/Advertisement-19-5-2016.pdf</p>
]]></description>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/27554/jrf-bioinformatics-at-actrec-navi-mumbai</guid>
  <pubDate>Mon, 30 May 2016 03:24:22 -0500</pubDate>
  <link></link>
  <title><![CDATA[JRF Bioinformatics at ACTREC, Navi Mumbai]]></title>
  <description><![CDATA[
<p>No. ACTREC/Advt./23/2016<br />JRF Bioinformatics recruitment in ACTREC (On contract Basis- Primeone Workforce Pvt. Ltd.)<br />Title : “Investigating the molecular basis of CaM/c-FLIP interaction to design specific c-FLIP inhibitor for modulating its anti-apoptotic function”.<br />Qualification : Master’s degree in bioinformatics, biochemistry, biotechnology and biological sciences from a recognized university with not less than 55% aggregate marks. Experience: Prior experience in modelling, protein-protein/ligand docking, Molecular dynamics simulation required. Knowledge in database development will be preferred.   </p>

<p>Pay Scale : Rs. 32,500/- <br />How to apply<br />Candidates fulfilling these requirements should pre-register by sending their application in the prescribed format with recent CV and contact details of 2 referees by e-mail to  ‘program.office@actrec.gov.in’ latest by  17.00 hrs on 23-06-2016. The interviews would be held on 27-06-2016 and only pre-registered candidates will be eligible to appear for interview. Candidates should report between 09.30 to 10.00 a.m. in Steno Pool,  3rd floor, Khanolkar Shodhika, ACTREC, Kharghar, Navi Mumbai.</p>

<p>More at http://www.actrec.gov.in/</p>
]]></description>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/27695/the-kingsley-lab</guid>
  <pubDate>Fri, 03 Jun 2016 09:55:10 -0500</pubDate>
  <link></link>
  <title><![CDATA[The Kingsley Lab]]></title>
  <description><![CDATA[
<p>The Molecular Basis of Vertebrate Evolution. Naturally occurring species show spectacular differences in morphology, physiology, behavior, disease susceptibility, and life span. Although the genomes of many organisms have now been completely sequenced, Kingsley lab still know relatively little about the specific DNA sequence changes that underlie interesting species-specific traits. Kingsley lab laboratory is using a combination of genetic and genomic approaches to identify the detailed molecular mechanisms that control evolutionary change in vertebrates.</p>
]]></description>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/27821/blobsplorer</guid>
	<pubDate>Tue, 14 Jun 2016 10:28:58 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/27821/blobsplorer</link>
	<title><![CDATA[Blobsplorer]]></title>
	<description><![CDATA[<p>Blobsplorer is a tool for interactive visualization of assembled DNA sequence data ("contigs") derived from (often unintentionally) mixed-species pools. It allows the simultaneous display of GC content, coverage, and taxonomic annotation for collections of contigs with a view to separating out those belonging to different taxa.</p>
<p>Blobsplorer is unlikely to be of use on its own as it requires contig data to be supplied in a format that involves considerable preprocessing (see below for a description). The easiest way to use Blobsplorer is as part of a workflow using scripts from <a href="https://github.com/blaxterlab/blobology">here</a>.</p><p>Address of the bookmark: <a href="http://nematodes.org/martin/blobsplorer/blobsplorer.html" rel="nofollow">http://nematodes.org/martin/blobsplorer/blobsplorer.html</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/27959/darkhorse</guid>
	<pubDate>Wed, 22 Jun 2016 05:37:38 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/27959/darkhorse</link>
	<title><![CDATA[DarkHorse]]></title>
	<description><![CDATA[<p><em>DarkHorse</em>&nbsp;is a bioinformatic method for rapid, automated identification and ranking of phylogenetically atypical proteins on a genome-wide basis. It works by selecting potential ortholog matches from a reference database of amino acid sequences, then using these matches to calculate a lineage probability index (LPI) score for each genome protein.</p>
<p>LPI scores are inversely proportional to the phylogenetic distance between database match sequences and the query genome. These scores are useful not only for large-scale<em>de novo</em>&nbsp;predictions of horizontally transferred proteins, but can also serve as an independent quality control test for potential horizontal transfer candidates identified by alternative methods, especially those based on nucleic acid signatures. Candidates having high LPI scores are unlikely to have been horizontally transferred, since they are highly conserved among closely related organisms.</p>
<p>One unique and powerful feature of the DarkHorse HGT Candidate database is the opportunity to explore the phylogenetic background of potential HGT donors as well as recipients. The breadth of the database allows not only query sequences, but also their database match partners to be evaluated for sequence similarity or novelty compared to taxonomically related organisms.</p>
<p><em>DarkHorse</em>&nbsp;is configurable for varying degrees of phylogenetic granularity and protein sequence conservation. Users should consult the&nbsp;<a href="http://darkhorse.ucsd.edu/#references">references</a>&nbsp;cited below for a complete explanation of parameter selection and result interpretation. A brief&nbsp;<a href="http://darkhorse.ucsd.edu/tutorial.html">tutorial</a>&nbsp;page is also available on-line.</p><p>Address of the bookmark: <a href="http://darkhorse.ucsd.edu/download.html" rel="nofollow">http://darkhorse.ucsd.edu/download.html</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/27961/nearhgt</guid>
	<pubDate>Wed, 22 Jun 2016 05:41:57 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/27961/nearhgt</link>
	<title><![CDATA[NearHGT]]></title>
	<description><![CDATA[<p>Horizontal gene transfer (HGT), the transfer of genetic material between organisms, is crucial for genetic innovation and the evolution of genome architecture. Existing HGT detection algorithms rely on a strong phylogenetic signal distinguishing the transferred sequence from ancestral (vertically derived) genes in its recipient genome. Detecting HGT between closely related species or strains is challenging, as the phylogenetic signal is usually weak and the nucleotide composition is normally nearly identical. Nevertheless, there is a great importance in detecting HGT between congeneric species or strains, especially in clinical microbiology, where understanding the emergence of new virulent and drug-resistant strains is crucial, and often time-sensitive.</p>
<p>We developed a novel, self-contained technique named&nbsp;<em>Near HGT</em>, based on the&nbsp;<em>synteny index</em>, to measure the divergence of a gene from its native genomic environment and used it to identify candidate HGT events between closely related strains. The method confirms candidate transferred genes based on the&nbsp;<em>constant relative mutability</em>&nbsp;(CRM). Using CRM, the algorithm assigns a confidence score based on &ldquo;unusual&rdquo; sequence divergence. A gene exhibiting exceptional deviations according to both synteny and mutability criteria, is considered a validated HGT product. We first employed the technique to a set of three&nbsp;<em>E. coli</em>&nbsp;strains and detected several highly probable horizontally acquired genes. We then compared the method to existing HGT detection tools using a larger strain data set.</p>
<p>When combined with additional approaches our new algorithm provides richer picture and brings us closer to the goal of detecting all newly acquired genes in a particular strain.</p>
<p><strong>Availability:</strong><span>&nbsp;The method is publicly available at</span><a href="http://research.haifa.ac.il/~ssagi/software/nearHGT.zip">http://research.haifa.ac.il/~ssagi/software/nearHGT.zip</a></p><p>Address of the bookmark: <a href="http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1004408" rel="nofollow">http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1004408</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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