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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/27845?offset=1320</link>
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	<description><![CDATA[]]></description>
	
	
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/27554/jrf-bioinformatics-at-actrec-navi-mumbai</guid>
  <pubDate>Mon, 30 May 2016 03:24:22 -0500</pubDate>
  <link></link>
  <title><![CDATA[JRF Bioinformatics at ACTREC, Navi Mumbai]]></title>
  <description><![CDATA[
<p>No. ACTREC/Advt./23/2016<br />JRF Bioinformatics recruitment in ACTREC (On contract Basis- Primeone Workforce Pvt. Ltd.)<br />Title : “Investigating the molecular basis of CaM/c-FLIP interaction to design specific c-FLIP inhibitor for modulating its anti-apoptotic function”.<br />Qualification : Master’s degree in bioinformatics, biochemistry, biotechnology and biological sciences from a recognized university with not less than 55% aggregate marks. Experience: Prior experience in modelling, protein-protein/ligand docking, Molecular dynamics simulation required. Knowledge in database development will be preferred.   </p>

<p>Pay Scale : Rs. 32,500/- <br />How to apply<br />Candidates fulfilling these requirements should pre-register by sending their application in the prescribed format with recent CV and contact details of 2 referees by e-mail to  ‘program.office@actrec.gov.in’ latest by  17.00 hrs on 23-06-2016. The interviews would be held on 27-06-2016 and only pre-registered candidates will be eligible to appear for interview. Candidates should report between 09.30 to 10.00 a.m. in Steno Pool,  3rd floor, Khanolkar Shodhika, ACTREC, Kharghar, Navi Mumbai.</p>

<p>More at http://www.actrec.gov.in/</p>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/27695/the-kingsley-lab</guid>
  <pubDate>Fri, 03 Jun 2016 09:55:10 -0500</pubDate>
  <link></link>
  <title><![CDATA[The Kingsley Lab]]></title>
  <description><![CDATA[
<p>The Molecular Basis of Vertebrate Evolution. Naturally occurring species show spectacular differences in morphology, physiology, behavior, disease susceptibility, and life span. Although the genomes of many organisms have now been completely sequenced, Kingsley lab still know relatively little about the specific DNA sequence changes that underlie interesting species-specific traits. Kingsley lab laboratory is using a combination of genetic and genomic approaches to identify the detailed molecular mechanisms that control evolutionary change in vertebrates.</p>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/27821/blobsplorer</guid>
	<pubDate>Tue, 14 Jun 2016 10:28:58 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/27821/blobsplorer</link>
	<title><![CDATA[Blobsplorer]]></title>
	<description><![CDATA[<p>Blobsplorer is a tool for interactive visualization of assembled DNA sequence data ("contigs") derived from (often unintentionally) mixed-species pools. It allows the simultaneous display of GC content, coverage, and taxonomic annotation for collections of contigs with a view to separating out those belonging to different taxa.</p>
<p>Blobsplorer is unlikely to be of use on its own as it requires contig data to be supplied in a format that involves considerable preprocessing (see below for a description). The easiest way to use Blobsplorer is as part of a workflow using scripts from <a href="https://github.com/blaxterlab/blobology">here</a>.</p><p>Address of the bookmark: <a href="http://nematodes.org/martin/blobsplorer/blobsplorer.html" rel="nofollow">http://nematodes.org/martin/blobsplorer/blobsplorer.html</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/27959/darkhorse</guid>
	<pubDate>Wed, 22 Jun 2016 05:37:38 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/27959/darkhorse</link>
	<title><![CDATA[DarkHorse]]></title>
	<description><![CDATA[<p><em>DarkHorse</em>&nbsp;is a bioinformatic method for rapid, automated identification and ranking of phylogenetically atypical proteins on a genome-wide basis. It works by selecting potential ortholog matches from a reference database of amino acid sequences, then using these matches to calculate a lineage probability index (LPI) score for each genome protein.</p>
<p>LPI scores are inversely proportional to the phylogenetic distance between database match sequences and the query genome. These scores are useful not only for large-scale<em>de novo</em>&nbsp;predictions of horizontally transferred proteins, but can also serve as an independent quality control test for potential horizontal transfer candidates identified by alternative methods, especially those based on nucleic acid signatures. Candidates having high LPI scores are unlikely to have been horizontally transferred, since they are highly conserved among closely related organisms.</p>
<p>One unique and powerful feature of the DarkHorse HGT Candidate database is the opportunity to explore the phylogenetic background of potential HGT donors as well as recipients. The breadth of the database allows not only query sequences, but also their database match partners to be evaluated for sequence similarity or novelty compared to taxonomically related organisms.</p>
<p><em>DarkHorse</em>&nbsp;is configurable for varying degrees of phylogenetic granularity and protein sequence conservation. Users should consult the&nbsp;<a href="http://darkhorse.ucsd.edu/#references">references</a>&nbsp;cited below for a complete explanation of parameter selection and result interpretation. A brief&nbsp;<a href="http://darkhorse.ucsd.edu/tutorial.html">tutorial</a>&nbsp;page is also available on-line.</p><p>Address of the bookmark: <a href="http://darkhorse.ucsd.edu/download.html" rel="nofollow">http://darkhorse.ucsd.edu/download.html</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/27961/nearhgt</guid>
	<pubDate>Wed, 22 Jun 2016 05:41:57 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/27961/nearhgt</link>
	<title><![CDATA[NearHGT]]></title>
	<description><![CDATA[<p>Horizontal gene transfer (HGT), the transfer of genetic material between organisms, is crucial for genetic innovation and the evolution of genome architecture. Existing HGT detection algorithms rely on a strong phylogenetic signal distinguishing the transferred sequence from ancestral (vertically derived) genes in its recipient genome. Detecting HGT between closely related species or strains is challenging, as the phylogenetic signal is usually weak and the nucleotide composition is normally nearly identical. Nevertheless, there is a great importance in detecting HGT between congeneric species or strains, especially in clinical microbiology, where understanding the emergence of new virulent and drug-resistant strains is crucial, and often time-sensitive.</p>
<p>We developed a novel, self-contained technique named&nbsp;<em>Near HGT</em>, based on the&nbsp;<em>synteny index</em>, to measure the divergence of a gene from its native genomic environment and used it to identify candidate HGT events between closely related strains. The method confirms candidate transferred genes based on the&nbsp;<em>constant relative mutability</em>&nbsp;(CRM). Using CRM, the algorithm assigns a confidence score based on &ldquo;unusual&rdquo; sequence divergence. A gene exhibiting exceptional deviations according to both synteny and mutability criteria, is considered a validated HGT product. We first employed the technique to a set of three&nbsp;<em>E. coli</em>&nbsp;strains and detected several highly probable horizontally acquired genes. We then compared the method to existing HGT detection tools using a larger strain data set.</p>
<p>When combined with additional approaches our new algorithm provides richer picture and brings us closer to the goal of detecting all newly acquired genes in a particular strain.</p>
<p><strong>Availability:</strong><span>&nbsp;The method is publicly available at</span><a href="http://research.haifa.ac.il/~ssagi/software/nearHGT.zip">http://research.haifa.ac.il/~ssagi/software/nearHGT.zip</a></p><p>Address of the bookmark: <a href="http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1004408" rel="nofollow">http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1004408</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/28199/genome-workbench-2107</guid>
	<pubDate>Fri, 01 Jul 2016 12:09:59 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/28199/genome-workbench-2107</link>
	<title><![CDATA[Genome Workbench 2.10.7]]></title>
	<description><![CDATA[<p>Genome Workbench 2.10.7 is here! New features include added support for local custom BLAST databases and improvements to Tree View.</p><p>For the full list of features, improvements and fixes, see the release notes:<a href="https://ncbi.nlm.nih.gov/tools/gbench/releasenotes" target="_blank">https://ncbi.nlm.nih.gov/tools/gbench/releasenotes</a></p><p>New Features</p><ul>
<li>BLAST Tool: added support for local custom BLAST databases</li>
<li>Graphical Sequence View: added log scaling option for graph tracks</li>
<li>Generic Table View:&nbsp;<a href="https://www.ncbi.nlm.nih.gov/tools/gbench/tutorial17">new tutorial</a>&nbsp;added</li>
</ul><p>Bug Fixes and Improvements</p><ul>
<li>Project Tree View: Genomic Collections/Assemblies now show accessions, not just names</li>
<li>Tree View: layout updated to better accommodate nodes of different sizes</li>
<li>Table Import Dialog (MacOS): fixed issue with table visibility</li>
<li>Fixed bug where different molecules IDs in GenBank could resolve to the same sequence</li>
<li>Graphical Sequence View: fixed issue where sequence track was not shown for some sequences</li>
<li>Graphical Sequence View: fixed protein coloration methods</li>
<li>Graphical Sequence View: improved rendering of Markers to better indicate boundaries and produce higher quality PDF images</li>
<li>Create Gene Model tool: fixed scenario when gene model tool failed with local sequences</li>
<li>Search View: ORF Finder &ndash; fixed incorrect protein lengths</li>
<li>Fixed bug with not opening project file (.gbp) on a click</li>
<li>Fixed issues in GVF import</li>
<li>Fixed BLAST Search tool against NCBI databases not working</li>
<li>Fixed tblastn (protein BLAST) not working in standalone mode</li>
<li>Fixed GTF export failure</li>
</ul>]]></description>
	<dc:creator>Gudiya Pal</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/28425/advertisement-for-junior-research-fellowjrf-at-school-of-computational-and-integrative-sciences-jawaharlal-nehru-university</guid>
  <pubDate>Thu, 14 Jul 2016 07:24:53 -0500</pubDate>
  <link></link>
  <title><![CDATA[Advertisement for Junior Research Fellow(JRF)  at School of Computational and Integrative Sciences  Jawaharlal Nehru University]]></title>
  <description><![CDATA[
<p>Advertisement for Junior Research Fellow(JRF) - (1)</p>

<p>Applications are invited for a post in DST, India funded Project entitled: "Positive and negative impacts of macromolecular crowding agents during target site location by DNA binding proteins – origin of optimal search at physiological ionic concentration (Reference Number: ECR/2016/000188) ''. The selected candidate will be appointed purely on temporary basis, initially for two years as a JRF that may be extended to one year of SRF based on the performance.</p>

<p>Position: Junior Research Fellow (1)</p>

<p>Qualifications &amp; Experience: Candidate must have a consistently good academic record with at least 60% marks in all throughout and must have qualified NET/GATE.</p>

<p>Desirable: Basic knowledge in the field of biophysics, molecular simulations and computational biology are desirable.</p>

<p>Salary: Consolidated Rs. 25,000 per month.</p>

<p>Tenure: The project duration is for three years and the selected candidate would be appointed after an interview. Appointment will be purely on temporary basis as stipulated by the existing rules of the University.</p>

<p>Interested candidates need to send an application to the address mentioned below mentioning the name of the project and post applied for (on the cover of the envelope).</p>

<p>The applications along with CV should be mailed at the address given below. Name, address, contact number and e. mail address of two referees must be enclosed with the application. The last date for the application is July 31st 2016.</p>

<p>Dr. Arnab Bhattacharjee (Principal Investigator) <br />Assistant Professor <br />School of Computational and Integrative Sciences <br />Jawaharlal Nehru University <br />New Delhi-110067 <br />E-mail: arnab@jnu.ac.in</p>

<p>Note: 1. Only shortlisted candidates will be communicated to appear in the interview at SCIS, JNU and no other communications in this regard will be entertained.</p>

<p>2. No TA/DA will be paid for appearing in interview.</p>
]]></description>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/28547/jrf-bioinformatics-at-iit-delhi</guid>
  <pubDate>Mon, 25 Jul 2016 03:26:20 -0500</pubDate>
  <link></link>
  <title><![CDATA[JRF Bioinformatics at IIT, Delhi]]></title>
  <description><![CDATA[
<p>No. IITD/IRD/RP03017/4254/Advertisement No.: IITD/IRD/093/2016<br />JRF Bioinformatics  job vacancies in Indian Institute of Technology Delhi (IIT Delhi)<br />Title : Elucidation of Pathologically Relevant miRNAs Responsible for Disease Progression and Resistance to Chemotherapy in Chronic Lymphocytic Leukemia (CLL) (RP03017)<br />Qualification : Candidates having first class B. Tech. / M.Sc. Degree or equivalent in Bioinformatics or Biotechnology with NET qualification. Desirable: Candidates having computer programming skills (C++, Python, Java, Web designing using Materialize frameworks, database management, offline software GUI development) with knowledge of Linux server environment and / or experience in next generation sequencing (NGS) data analysis, MD simulations will be preferred.<br />No. of Post : 01<br />Pay Scale : Rs.25,000/-<br />How to apply<br />Walk-in test / interview will be held on 04/08/2016, 03.00 p.m. at Committee Room No. 230, Block-I, Department of Biochemical Engineering &amp; Biotechnology, Indian Institute of Technology Delhi, Hauz Khas, New Delhi-110016.</p>

<p>More at http://ird.iitd.ac.in/sites/default/files/jobs/project/IITD-IRD-093-2016.pdf</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/28566/emboss-apps</guid>
	<pubDate>Wed, 27 Jul 2016 06:00:41 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/28566/emboss-apps</link>
	<title><![CDATA[EMBOSS Apps]]></title>
	<description><![CDATA[<p>The programs are listed in alphabetical order, Look at the individual applications or go to the&nbsp;<a href="http://emboss.sourceforge.net/apps/release/6.6/emboss/apps/groups.html">GROUPS</a>&nbsp;page to search by category.</p>
<p><a href="http://emboss.sourceforge.net/apps/release/6.6/embassy/index.html">EMBASSY applications</a>&nbsp;are described in separate documentation for each package.</p>
<h3><a name="current" id="current"></a>Applications&nbsp;in the&nbsp;<a href="ftp://emboss.open-bio.org/pub/EMBOSS/">current release</a></h3><p>Address of the bookmark: <a href="http://emboss.sourceforge.net/apps/release/6.6/emboss/apps/" rel="nofollow">http://emboss.sourceforge.net/apps/release/6.6/emboss/apps/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/28602/srf-and-jrf-bioinformatics-at-tezpur-university-napaam</guid>
  <pubDate>Wed, 03 Aug 2016 03:47:38 -0500</pubDate>
  <link></link>
  <title><![CDATA[SRF and JRF Bioinformatics at Tezpur University, Napaam]]></title>
  <description><![CDATA[
<p>Applications are invited for the following temporary positions unde MHRD sponsored Centre of Excellence<br />in the Department of Computer Science and Engineering (CSE), Tezpur University<br /> <br />Qualification<br />and Experience : Senior Research Fellow (SRF) and JRF : First Class in M.E/M.Tech in CSE/IT/ECE with research<br />experience in relevant fields of research (Candidates having valid GATE/NET Score would be preferred).</p>

<p> <br />Fellowship: Rs. 18,000/- per month (fixed)<br /> <br />Duration : 2 (Two) years and may be extended<br />depending on status of the project<br /> <br />Age Limit: Candidates should not be more than 32 years of<br />age in case of SRF and 28 years of age in case of JRF and TA. Upper age limit may be relaxed up to 5<br />years in the case of candidate belonging to SC/ ST/ OBC/ Women/ Differently abled.<br /> <br />How to Apply:<br />Interested candidates may send their application on plain paper by post along with his/her educational<br />qualifications, research experience certificates (for SRF), 02 copies of recent passport/stamp size photographs<br />and contact phone number to Professor D.K Bhattacharyya, Principal Investigator, Department of Computer<br />Science &amp; Engineering, Tezpur University, Napaam – 784 028, or mail it to dkb@tezu.ernet.in<br />(or to smh@tezu.ernet.in) within 15 days of publication of this advertisement.<br /> <br />No TA/DA shall<br />be paid for attending the interview.<br /> <br />For more details: http://www.tezu.ernet.in/ProjectWalkin/Advt-DoRD-CSE-DKB-20-225-6779-A.pdf</p>
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