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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/27967?offset=780</link>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/22286/jrf-bioinformatics-pune-university</guid>
  <pubDate>Wed, 06 May 2015 06:21:09 -0500</pubDate>
  <link></link>
  <title><![CDATA[JRF Bioinformatics @ Pune University]]></title>
  <description><![CDATA[
<p>Pune University is inviting applications from indian citizens for recruiting following posts:</p>

<p>Vacancies:<br />Junior Research Fellow-04<br />Age Limits:<br />Candidates age should be not more than 28 years.<br />Qualification:<br />Candidates should possess M.Sc in Microbiology/ Marine microbiology/Marine Biotechnology/ Bioinformatics/Zoology or equivalent degree with minimum 60% marks.<br />Selection Process:<br />Shortlisted candidates will be called for interview.<br />How to Apply:<br />Eligible candidates may send their applications in the prescribed format along with CV in an envelope should be superscribed as the "Application for the post of JRF" to Head Department of Zoology, Savitribai Phule Pune University on or before 10-05-2015.<br />Last Date:<br />10-05-2015</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/poll/view/23590/will-minion-nanopore-sequencing-increase-the-number-of-next-generation-sequencing-projects</guid>
	<pubDate>Tue, 04 Aug 2015 05:14:07 -0500</pubDate>
	<link>https://bioinformaticsonline.com/poll/view/23590/will-minion-nanopore-sequencing-increase-the-number-of-next-generation-sequencing-projects</link>
	<title><![CDATA[Will MinION Nanopore sequencing increase the number of Next Generation Sequencing projects?]]></title>
	<description><![CDATA[<p>Will MinION Nanopore sequencing increase the number of Next Generation Sequencing projects?</p>]]></description>
	<dc:creator>Strand</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/22352/affy-has-acquired-eureka-genomics-for-15m</guid>
	<pubDate>Wed, 20 May 2015 15:11:20 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/22352/affy-has-acquired-eureka-genomics-for-15m</link>
	<title><![CDATA[Affy has acquired Eureka Genomics for 15M $]]></title>
	<description><![CDATA[<p>Affymetrix Acquires Assets Of Eureka Genomics Corporation To Provide High Throughput And Economical Crop And Animal Genotyping</p><p>http://www.thestreet.com/story/13151062/1/affymetrix-acquires-assets-of-eureka-genomics-corporation-to-provide-high-throughput-and-economical-crop-and-animal-genotyping.html</p>]]></description>
	<dc:creator>Martin Jones</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/32875/finishing</guid>
	<pubDate>Sat, 20 May 2017 15:50:20 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/32875/finishing</link>
	<title><![CDATA[Finishing !!]]></title>
	<description><![CDATA[<p>The process of&nbsp;<em>finishing</em>&nbsp;a genome and moving it from a&nbsp;<em>draft</em>&nbsp;stage (the result of sequencing and initial assembly) to a complete genome is typically a time and resource intensive task. The advent of new sequencing technologies has come with its own set of opportunities and pitfalls in the finishing process. While genomes can now be sequenced to high redundancy in a cost-effective manner, the process of assembling the genomes is more challenging and often draft genomes are fragmented into hundreds of contigs. Correspondingly, the task of producing the complete genome can involve months of lab work and thousands of finishing experiments and is usually done in large genome centers.</p>
<p>The work in our lab has focussed on computational approaches to speed-up the finishing process. Specifically, we have explored the use of optical mapping and mate-pair data to augment assemblies and direct finishing experiments. The tools developed in our lab have been used in several finishing projects, producing complete genomes (and near-complete ones) with surprisingly little computational and experimental effort (Nagarajan et al., in submission). The executables (as well as source code) for these tools are freely available here:</p>
<ul>
<li><strong>Scaffolding using Optical Restriction Mapping</strong><br>Optical Maps are global, ordered maps of restriction site locations in a genome. This information can be quite useful in scaffolding contigs from a shotgun assembly to guide the finishing process. A set of programs to exploit optical maps for assembly can be found here:&nbsp;<a href="http://www.cbcb.umd.edu/finishing/soma-v2.tar.gz">SOMA v2.0 (63 MB tar.gz file)</a>. This version of SOMA contains several improvements to programs in v1.0 as well as new scripts for working with multiple maps, contig graphs and scaffolds.&nbsp;<br><br></li>
<li><strong>Augmenting assemblies with mate-pair data</strong><br>Mate-pair information can be valuable in augmenting short-read assemblies and reconstructing the genome as larger scaffolds. AMOS-Hybrid is a pipeline written in the AMOS framework (open-source assembly tools) to merge arbitrary mated reads into an existing assembly and merge contigs and create scaffolds where possible. Source code and executables for AMOS-Hybrid are available here:&nbsp;<a href="http://www.cbcb.umd.edu/finishing/AMOS-Hybrid-v1.tar.gz">AMOS-Hybrid v1.0 (142 MB tar.gz file)</a>.&nbsp;<br><br></li>
<li><strong>Assembly and sequence-composition guided finishing</strong><br>Contigs from a shotgun assembly are typically linked together in a graph structure that can serve to guide finishing and in some case close gaps&nbsp;<em>in-silico</em>. Also, in many cases, sequence composition of contigs can provide clues to fill gaps in scaffolds. A set of scripts to automate some of these tasks can be found here:&nbsp;<a href="http://www.cbcb.umd.edu/finishing/finishing-v1.tar.gz">Finishing Scripts v1.0 (63 MB tar.gz file)</a>.&nbsp;</li>
</ul>
<p>http://www.cbcb.umd.edu/finishing/</p><p>Address of the bookmark: <a href="http://www.cbcb.umd.edu/finishing/" rel="nofollow">http://www.cbcb.umd.edu/finishing/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>

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  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/22402/alessandra-carbone-lab</guid>
  <pubDate>Tue, 26 May 2015 08:54:34 -0500</pubDate>
  <link></link>
  <title><![CDATA[Alessandra Carbone Lab]]></title>
  <description><![CDATA[
<p>Our group works on various problems connected with the functioning and evolution of biological systems. We use mathematical tools, coming from statistics and combinatorics, algorithmic tools and molecular physics tools to study basic principles of cellular functioning starting from genomic data. We run several projects in parallel, all aiming at understanding the basic principles of evolution and co-evolution of molecular structures in the cell. They are intimately linked to each other.</p>

<p>Our main research themes are:</p>

<p>Domain annotation and metagenomics <br />Transcriptomics and sequence analysis<br />Protein evolution and interactions<br />Protein conformational dynamics</p>

<p>More at http://www.lcqb.upmc.fr/AnalGenom/home.html</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/34493/plast-a-fast-accurate-and-ngs-scalable-bank-to-bank-sequence-similarity-search-tool</guid>
	<pubDate>Fri, 01 Dec 2017 04:10:54 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/34493/plast-a-fast-accurate-and-ngs-scalable-bank-to-bank-sequence-similarity-search-tool</link>
	<title><![CDATA[PLAST: A fast, accurate and NGS scalable bank-to-bank sequence similarity search tool]]></title>
	<description><![CDATA[<p><strong>PLAST is a fast, accurate and NGS scalable bank-to-bank sequence similarity search tool providing significant accelerations of seeds-based heuristic comparison methods, such as the Blast suite of algorithms.</strong></p>
<p><strong>Relying on unique software architecture, PLAST takes full advantage of recent multi-core personal computers without requiring any additional hardware devices.</strong></p>
<p>PLAST stands for&nbsp;<em>Parallel Local Sequence Alignment Search Tool&nbsp;</em>and is was&nbsp;<a href="http://www.biomedcentral.com/1471-2105/10/329" target="_blank">published in BMC Bioinformatics.</a></p>
<p>PLAST is a general purpose sequence comparison tool providing the following benefits:</p>
<ul>
<li>PLAST is a high-performance sequence comparison tool designed to compare two sets of sequences (query vs. reference),</li>
<li>Reduces the processing time of sequences comparisons while providing highest quality results,</li>
<li>Contains a fully integrated data filtering engine capable of selecting relevant hits with user-defined criteria (E-Value, identity, coverage, alignment length, etc.),</li>
<li>Does not require any additional hardware, since it is a software solution. It is easy to install, cost-effective, takes full advantage of multi-core processors and uses a small RAM footprint,</li>
<li>Ready to be used on desktop computer, cluster, cloud as well as within distributed system running Hadoop.</li>
</ul>
<p>https://plast.inria.fr/</p><p>Address of the bookmark: <a href="https://plast.inria.fr/" rel="nofollow">https://plast.inria.fr/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/22414/x-shirley-liu-lab</guid>
  <pubDate>Tue, 26 May 2015 17:28:23 -0500</pubDate>
  <link></link>
  <title><![CDATA[X. Shirley Liu Lab]]></title>
  <description><![CDATA[
<p>The research in our laboratories are focused on the following three areas: </p>

<p>Bioinformatics<br />Cancer<br />Epigenetics</p>

<p>More at http://liulab.dfci.harvard.edu/</p>
]]></description>
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<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/36812/porechop-tool-for-finding-and-removing-adapters-from-oxford-nanopore-reads</guid>
	<pubDate>Tue, 29 May 2018 07:33:44 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/36812/porechop-tool-for-finding-and-removing-adapters-from-oxford-nanopore-reads</link>
	<title><![CDATA[Porechop:  tool for finding and removing adapters from Oxford Nanopore reads]]></title>
	<description><![CDATA[<p>Porechop is a tool for finding and removing adapters from <a href="https://nanoporetech.com/">Oxford Nanopore</a> reads. Adapters on the ends of reads are trimmed off, and when a read has an adapter in its middle, it is treated as chimeric and chopped into separate reads. Porechop performs thorough alignments to effectively find adapters, even at low sequence identity.</p>
<p>Porechop also supports demultiplexing of Nanopore reads that were barcoded with the <a href="https://store.nanoporetech.com/native-barcoding-kit-1d.html">Native Barcoding Kit</a>, <a href="https://store.nanoporetech.com/pcr-barcoding-kit-96.html">PCR Barcoding Kit</a> or <a href="https://store.nanoporetech.com/rapid-barcoding-sequencing-kit.html">Rapid Barcoding Kit</a>.</p><p>Address of the bookmark: <a href="https://github.com/rrwick/Porechop" rel="nofollow">https://github.com/rrwick/Porechop</a></p>]]></description>
	<dc:creator>Rahul Nayak</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/22436/ra-bioinformatics-at-national-bureau-of-animal-genetic-resources</guid>
  <pubDate>Thu, 28 May 2015 19:25:33 -0500</pubDate>
  <link></link>
  <title><![CDATA[RA Bioinformatics at NATIONAL BUREAU OF ANIMAL GENETIC RESOURCES]]></title>
  <description><![CDATA[
<p>NATIONAL BUREAU OF ANIMAL GENETIC RESOURCES</p>

<p>Near Basant Vihar G.T. Road Bypass P.O. Box No.129</p>

<p>Karnal - 132001 (Haryana)</p>

<p>WALK-IN-INTERVIEW</p>

<p>A walk-in-Interview is proposed to be held at National Bureau of Animal Genetic Resources, Karnal (Haryana)-132001 at 10:30 AM on 10.06.2015 to select One Research Associate as per details given below:</p>

<p>1. One post of Research Associate under National Fellow project entitled “Genome data mining to unravel molecular basis of thermotolerance and adaptation to diverse environments in native cattle and buffaloes”.</p>

<p>The post duration is Upto 22.05.2016 or earlier &amp; Co-terminus with the project.</p>

<p>Essential Qualifications: Master’s degree (M.Sc. / M.V.Sc.) in Biotechnology/ Animal Genetics and Breeding/ Life Sciences/ Bioinformatics with 2 Years research experience in relevant subject or Ph.D in any of the above subjects.</p>

<p>Desirable: Working Experience in molecular biology, gene expression/ microarray data analysis, SNP genotyping and sequence data analysis, mammalian cell-culture handling etc.</p>

<p>Emolument: Rs. 23,000/- per month + HRA as per admissibility</p>

<p>Research Associate: ONE</p>

<p>Duration of engagement: Upto 22.05.2016 or earlier Co-terminus with the project</p>

<p>Age Limit:  40 years for Men  45 years for women as on date of interview</p>

<p>Note: Relaxation in age will be admissible for SC/ST &amp; OBC candidates as per Govt. of India /ICAR norms</p>

<p>1. The applicants must bring with them original documents and brief of research work done during post graduation along with a set of photocopy and latest two passport size photographs. 2. A panel of selected candidates will also be made which may be utilized for filling of positions of shorter durations in future if demand arises. 3. Experience certificate in original, if any 4. The above positions are purely on temporary basis and are coterminus with the project. No TA/DA will be paid to attend the interview. 5. Any other clarifications can be had on the date of interview. 6. The Director’s decision will be final and binding on all respects.</p>

<p>Advertisement: http://210.212.93.85/RAadvertisiment.pdf</p>
]]></description>
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<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/37233/rna-seq-analysis-workshop-course-materials</guid>
	<pubDate>Tue, 03 Jul 2018 08:14:14 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/37233/rna-seq-analysis-workshop-course-materials</link>
	<title><![CDATA[RNA-seq Analysis Workshop Course Materials]]></title>
	<description><![CDATA[RNAseq can be roughly divided into two "types":

Reference genome-based - an assembled genome exists for a species for which an RNAseq experiment is performed. It allows reads to be aligned against the reference genome and significantly improves our ability to reconstruct transcripts. This category would obviously include humans and most model organisms but excludes the majority of truly biologically intereting species (e.g., Hyacinth macaw);

Reference genome-free - no genome assembly for the species of interest is available. In this case one would need to assemble the reads into transcripts using de novo approaches. This type of RNAseq is as much of an art as well as science because assembly is heavily parameter-dependent and difficult to do well.
In this lesson we will focus on the Reference genome-based type of RNA seq.

http://chagall.med.cornell.edu/RNASEQcourse/<p>Address of the bookmark: <a href="http://chagall.med.cornell.edu/RNASEQcourse/" rel="nofollow">http://chagall.med.cornell.edu/RNASEQcourse/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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