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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/27971?offset=840</link>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/pages/view/42813/bioinformatics-in-africa-part5-nigeria</guid>
	<pubDate>Sat, 06 Feb 2021 21:13:47 -0600</pubDate>
	<link>https://bioinformaticsonline.com/pages/view/42813/bioinformatics-in-africa-part5-nigeria</link>
	<title><![CDATA[Bioinformatics in Africa: Part5 - Nigeria]]></title>
	<description><![CDATA[<p>Covenant University (CU)&shy;Ota:<br />Covenant University (with her enriching and growing state&shy;of&shy;the&shy;art laboratories in the area of &nbsp;science and technology, arts, business and social sciences) is presently the Best University in &nbsp;Nigeria (Private University category), based on the recent over&shy;all rating just concluded by the &nbsp;Nigeria &nbsp; University &nbsp; Commission &nbsp; (NUC). &nbsp; Recently, &nbsp; Covenant &nbsp; University &nbsp; has &nbsp; initiated &nbsp; the &nbsp;establishment of a Centre for Applied Biotech, Bio&shy;Informatics and Microbiology (CBBM) to be &nbsp;situated at the University. The institute has been designed to be a Public&shy;Private Partnership for a productive synergy b/w Academia, Industry and Government. The whole concept is still evolving &nbsp;and more details will be release soon. As regards CBBM, a dedicated computing lab is in plan, but even our computing capacity is &nbsp;presently enormous. In the department of Computer and Information Sciences, we have more than &nbsp;250 Pentium 4 PCs set aside for teaching and research purposes. Furthermore, we have several &nbsp;moderate speed PCs at the Postgraduate research lab and our engineering departments and units. &nbsp;Our wet lab facilities is presently minimal (basic for teaching), the Centre requirement as it touches &nbsp;the wet&shy;laboratories is also set to upgrade this to basic tools expected at an international centre of learning.</p><p>University&nbsp;of&nbsp;Ibadan&nbsp;(UIB)&shy;Ibadan:<br />There&nbsp;has&nbsp;been&nbsp;significant&nbsp;increase&nbsp;in&nbsp;the&nbsp;number&nbsp;of&nbsp;bioinformatics&nbsp;activities&nbsp;in&nbsp;Nigeria&nbsp;(and&nbsp;West Africa)&nbsp;since&nbsp;2003&nbsp;when&nbsp;the&nbsp;program&nbsp;was&nbsp;initiated&nbsp;by&nbsp;the&nbsp;West&nbsp;African&nbsp;Biotechnology&nbsp;Workshops Series&nbsp;(WABWS,&nbsp;http://www.wabw.org)&nbsp;at&nbsp;the&nbsp;University&nbsp;of&nbsp;Ibadan,&nbsp;Nigeria&nbsp;(in&nbsp;collaboration&nbsp;with&nbsp; the&nbsp;South&nbsp;African&nbsp;National&nbsp;Bioinformatics&nbsp;Institute&nbsp;(SANBI,&nbsp;http:/www.sanbi.ac.za).&nbsp;Workshops&nbsp; that&nbsp;were&nbsp;open&nbsp;to&nbsp;scientists&nbsp;from&nbsp;all&nbsp;African&nbsp;countries&nbsp;have&nbsp;seen&nbsp;a&nbsp;very&nbsp;high&nbsp;number&nbsp;of&nbsp;applications&nbsp; from&nbsp;scientists&nbsp;based&nbsp;in&nbsp;West&nbsp;Africa.&nbsp;The&nbsp;encouraging&nbsp;desire&nbsp;to&nbsp;acquire&nbsp;cutting&shy;edge&nbsp;skills&nbsp;to&nbsp; computational&nbsp;process&nbsp;data&nbsp;and&nbsp;extract&nbsp;useful&nbsp;knowledge&nbsp;from&nbsp;genome&nbsp;projects&nbsp;led&nbsp;to&nbsp;the&nbsp;interest&nbsp;of&nbsp; the&nbsp;West&nbsp;African&nbsp;Biotechnology&nbsp;Workshops&nbsp;(WABW)&nbsp;to&nbsp;develop&nbsp;an&nbsp;agenda&nbsp;to&nbsp;address&nbsp;the&nbsp; bioinformatics&nbsp;skills&nbsp;gap&nbsp;among&nbsp;scientists&nbsp;in&nbsp;West&nbsp;Africa.&nbsp;An&nbsp;increased&nbsp;commitment&nbsp;from&nbsp;agencies&nbsp; like&nbsp;NEPAD&nbsp;would&nbsp;be&nbsp;required&nbsp;in&nbsp;the&nbsp;provision&nbsp;of&nbsp;infrastructure&nbsp;to&nbsp;establish&nbsp;and&nbsp;sustain&nbsp;regional&nbsp; and&nbsp;national&nbsp;networks.</p><p>University&nbsp;of&nbsp;Ilorin&nbsp;(UIL)&shy;Ilorin:<br />The&nbsp;University&nbsp;of&nbsp;Ilorin&nbsp;was&nbsp;established&nbsp;in&nbsp;1976&nbsp;by&nbsp;the&nbsp;Federal&nbsp;Government&nbsp;of&nbsp;Nigeria.&nbsp; Bioinformatics&nbsp;activities&nbsp;started&nbsp;at&nbsp;the&nbsp;University&nbsp;in&nbsp;February&nbsp;2003&nbsp;with&nbsp;the&nbsp;establishment&nbsp;of&nbsp;the&nbsp; West&nbsp;African&nbsp;Bioinformatics&nbsp;Research&nbsp;Initiative&nbsp;(WABRI).&nbsp;However,&nbsp;progress&nbsp;has&nbsp;been&nbsp;rather&nbsp;slow&nbsp; due&nbsp;to&nbsp;inadequate&nbsp;funding.&nbsp;We&nbsp;are&nbsp;mainly&nbsp;engaged&nbsp;in&nbsp;Bioinformatics&nbsp;training&nbsp;at&nbsp;the&nbsp;introductory&nbsp; level&nbsp;and&nbsp;proteomics&nbsp;studies&nbsp;on&nbsp;various&nbsp;species&nbsp;of&nbsp;malaria&nbsp;parasites.&nbsp;Recently,&nbsp;we&nbsp;became&nbsp;interested&nbsp; in&nbsp;comparative&nbsp;genome&nbsp;analysis&nbsp;of&nbsp;various&nbsp;species&nbsp;of &nbsp;Plasmodium&nbsp; and&nbsp;the&nbsp;comparison&nbsp;of&nbsp; chloroquine&nbsp;sensitive&nbsp;and&nbsp;chloroquine&nbsp;resistant&nbsp;strains&nbsp;of&nbsp;Plasmodium&nbsp;falciparum.&nbsp;Other&nbsp;activities&nbsp; and&nbsp;areas&nbsp;of&nbsp;interest&nbsp;can&nbsp;be&nbsp;seen&nbsp;on&nbsp;our&nbsp;website,&nbsp;http://www.wabri.org,&nbsp;although&nbsp;not&nbsp;all&nbsp;our&nbsp; proposed&nbsp;interests&nbsp;have&nbsp;been&nbsp;fully&nbsp;implemented&nbsp;due&nbsp;to&nbsp;our&nbsp;level&nbsp;of&nbsp;funding.</p><p>Training:<br />The&nbsp;University&nbsp;of&nbsp;Ilorin&nbsp;has&nbsp;introduced&nbsp;M.Sc.&nbsp;and&nbsp;Ph.D.&nbsp;programmes&nbsp;in&nbsp;Computer&nbsp;Science&nbsp;(with&nbsp; options&nbsp;in&nbsp;Bioinformatics).&nbsp;The&nbsp;programme&nbsp;is&nbsp;based&nbsp;in&nbsp;the&nbsp;Department&nbsp;of&nbsp;Computer&nbsp;Science&nbsp;and&nbsp; emphasis&nbsp;is&nbsp;on&nbsp;the&nbsp;development&nbsp;of&nbsp;algorithms&nbsp;to&nbsp;solve&nbsp;problems&nbsp;in&nbsp;bioinformatics. The&nbsp;Covenant&nbsp;University&nbsp;offers&nbsp;M.Sc.&nbsp;and&nbsp;Ph.D&nbsp;in&nbsp;Computer&nbsp;Science&nbsp;with&nbsp;option&nbsp;in&nbsp;Bioinformatics&nbsp; (Computational&nbsp;Biology).&nbsp;Furthermore,&nbsp;through&nbsp;affiliated&nbsp;departments,&nbsp;the&nbsp;CBBM&nbsp;is&nbsp;been&nbsp;design&nbsp;to&nbsp;award&nbsp;Diploma&nbsp;and&nbsp;Degree&nbsp;certificates&nbsp;in&nbsp;Biotechnology.</p><p>Web&nbsp;sites&nbsp;and&nbsp;links: http://www.covenantuniversity.com http://www.run.edu.ng http://www.uniben.edu http://www.wabri.org http://www.wabw.org http://www.unilorin.edu.ng http://www.wabri.org http://www.asopah.org</p>]]></description>
	<dc:creator>BioStar</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/4656/pandey-lab</guid>
  <pubDate>Fri, 20 Sep 2013 13:19:18 -0500</pubDate>
  <link></link>
  <title><![CDATA[Pandey Lab]]></title>
  <description><![CDATA[
<p>The Pandey Lab at Johns Hopkins University is a Systems Biology lab that combines molecular biology, analytical chemistry and computational biology with various "Omics" technologies including genomics and proteomics to understand signaling pathways and to identify therapeutic targets and biomarkers in a number of cancers.</p>

<p>More at http://pandeylab.igm.jhmi.edu/</p>

<p>http://scholar.google.com/citations?user=OhuG0FcAAAAJ&amp;hl=en</p>
]]></description>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/42953/ra-bioinformatics-at-sir-ganga-ram-hospital-new-delhi</guid>
  <pubDate>Sun, 14 Mar 2021 10:40:18 -0500</pubDate>
  <link></link>
  <title><![CDATA[RA Bioinformatics at Sir Ganga Ram Hospital, New Delhi]]></title>
  <description><![CDATA[
<p>Opportunities available at Institute of Medical Genetics &amp; Genomics, Sir Ganga Ram Hospital, New Delhi.</p>

<p>1) Senior Research Fellow under ICMR Project: M.Sc. (Life Sciences) with 2 years of experience (preferable in the field of Bioinformatics) or MBBS Degree.</p>

<p>2) Research Associate under ICMR Project: . Ph.D.(Life Science/Biotechnology/Bioinformatics) or equivalent degree or having 3 years of research, teaching and design and development experience after M.Tech with at least one research paper in science Citation Indexed (SCI) Journal.<br />Work experience in the area of Human genomics/Next Generation Sequencing data analysis/Big data genomics would be preferred.<br />Application link:</p>

<p>https://sgrh.com/joblist</p>

<p>Post Code: 2023, 2024</p>
]]></description>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/4873/vveks-lab</guid>
  <pubDate>Thu, 26 Sep 2013 11:11:39 -0500</pubDate>
  <link></link>
  <title><![CDATA[Vvek's Lab]]></title>
  <description><![CDATA[
<p>Broad Area of Research: RNA biology (microRNA, lncRNA), Stem cells, Functional genomics, Epigenomics and Cancer</p>

<p>RNAs, especially non-coding RNAs (such as microRNA, long ncRNAs) are recently identified to be very abundant in mammalian organisms and play some key roles in gene expression regulation, gene silencing, and also implicated in disease progression, stem cell pluripotency etc. Current research activities of our lab include analysis of expression pattern of ncRNAs by microarray and next-gen sequencing data and understanding the role of miRNAs or other regulatory RNAs in various diseases, especially cancer and validation by reporter assays (renilla/luciferase) and other experimental tools.</p>

<p>More @ http://vvekslab.in/index.html</p>
]]></description>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/43341/nigerian-bioinformatics-and-genomics-network-nbgn</guid>
  <pubDate>Tue, 31 Aug 2021 08:29:40 -0500</pubDate>
  <link></link>
  <title><![CDATA[Nigerian Bioinformatics and Genomics Network (NBGN)]]></title>
  <description><![CDATA[
<p>This is to announce the second official conference of the Nigerian Bioinformatics and Genomics Network (NBGN). October 11-13,2021 at Landmark University, Omu-Aran, Kwara State and Zoom ( conference link to be announced soon</p>

<p>#NBGN21</p>

<p>www.nbgn21conference.com</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/videolist/watch/5462/showreel-2008-cortical-studios</guid>
	<pubDate>Sat, 12 Oct 2013 18:33:40 -0500</pubDate>
	<link>https://bioinformaticsonline.com/videolist/watch/5462/showreel-2008-cortical-studios</link>
	<title><![CDATA[Showreel 2008 - Cortical Studios]]></title>
	<description><![CDATA[<iframe width="" height="" src="https://www.youtube-nocookie.com/embed/qrReqMKe7Xg" frameborder="0" allowfullscreen></iframe>We are a bioinformatics company that combines 3D animation, multimedia and scientific knowledge to meet your communication needs. With our academic background in the fields of biotechnology and molecular cellbiology and our computer expertise we provide cutting edge 3D animation productions for even the most complex projects. We translate complex scientific information into comprehensible artistic imagery in order to improve communication in the life sciences. Please feel free to contact us with any questions regarding the possibilities for your unique project.

Cortical Studios
Keizersgracht 8
1015 CN
Amsterdam
The Netherlands
info@corticalstudios.nl
www.corticalstudios.nl]]></description>
	
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	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/43670/useful-bioinformatics-analysis-tools</guid>
	<pubDate>Thu, 23 Dec 2021 23:10:02 -0600</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/43670/useful-bioinformatics-analysis-tools</link>
	<title><![CDATA[Useful Bioinformatics Analysis Tools !]]></title>
	<description><![CDATA[<h3><a href="http://sun.aei.polsl.pl/REFRESH/index.php?page=projects&amp;project=cometa&amp;subpage=about">CoMeta</a></h3><p><strong>Classificier of reads from metagenomic sequencing experiments.</strong></p><p><span>&bull;&nbsp;&nbsp;Kawulok, J., Deorowicz, S.,&nbsp;</span><em>CoMeta: Classification of Metagenomes Using k-mers</em><span>,&nbsp;</span><a href="http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0121453">PLOS ONE,&nbsp;</a><span>2015; 10(4):1&ndash;23,</span></p><h3><a href="http://sun.aei.polsl.pl/REFRESH/index.php?page=projects&amp;project=CoMSA&amp;subpage=about">CoMSA</a></h3><p><strong>Compressor of multiple sequence alignments of proteins.</strong></p><p><span>&bull;&nbsp;&nbsp;Deorowicz, S., Walczyszyn, J., Debudaj-Grabysz, A.,&nbsp;</span><em>CoMSA: compression of protein multiple sequence alignment files</em><span>,&nbsp;</span><a href="https://doi.org/10.1093/bioinformatics/bty619">Bioinformatics,&nbsp;</a><span>2019; 35(2):22&ndash;234,</span></p><h3><a href="http://sun.aei.polsl.pl/REFRESH/index.php?page=projects&amp;project=dsrc&amp;subpage=about">DSRC</a></h3><p><strong>Compressor of sequencing reads.</strong></p><p><span>&bull;&nbsp;&nbsp;Roguski, L., Deorowicz, S.,&nbsp;</span><em>DSRC 2: Industry-oriented compression of FASTQ files</em><span>,&nbsp;</span><a href="http://bioinformatics.oxfordjournals.org/content/30/15/2213">Bioinformatics,&nbsp;</a><span>2014; 30(15):2213&ndash;2215,</span><br /><span>&bull;&nbsp;&nbsp;Deorowicz, S., Grabowski, Sz.,&nbsp;</span><em>Compression of DNA sequences in FASTQ format</em><span>,&nbsp;</span><a href="http://bioinformatics.oxfordjournals.org/">Bioinformatics,&nbsp;</a><span>2011; 27(6):860&ndash;862,</span></p><h3><a href="http://sun.aei.polsl.pl/REFRESH/index.php?page=projects&amp;project=famsa&amp;subpage=about">FAMSA</a></h3><p><strong>Multiple sequence alignment designed for huge families of proteins (even containing hundreds of thousands of sequences).</strong></p><p><span>&bull;&nbsp;&nbsp;Deorowicz, S., Debudaj-Grabysz, A., Gudys, A.,&nbsp;</span><em>FAMSA: Fast and accurate multiple sequence alignment of huge protein families</em><span>,&nbsp;</span><a href="http://www.nature.com/articles/srep33964">Scientific Reports,&nbsp;</a><span>2016; 6(33964):</span></p><h3><a href="http://sun.aei.polsl.pl/REFRESH/index.php?page=projects&amp;project=fastore&amp;subpage=about">FaStore</a></h3><p><strong>Compressor of FASTQ files.</strong></p><p><span>&bull;&nbsp;&nbsp;Roguski, L., Ochoa, I., Hernaez, M., Deorowicz, S.,&nbsp;</span><em>FaStore - a space-saving solution for raw sequencing data</em><span>,&nbsp;</span><a href="https://doi.org/10.1093/bioinformatics/bty205">Bioinformatics,&nbsp;</a><span>2018; 34(16):2748&ndash;2756,</span></p><h3><a href="http://sun.aei.polsl.pl/REFRESH/index.php?page=projects&amp;project=fqsqueezer&amp;subpage=about">FQSqueezer</a></h3><p><strong>Experimental high-end compressor of FASTQ files.</strong></p><p><span>&bull;&nbsp;&nbsp;Deorowicz, S.,&nbsp;</span><em>FQSqueezer: k-mer-based compression of sequencing data</em><span>,&nbsp;</span><a href="https://www.nature.com/articles/s41598-020-57452-6">Scientific Reports,&nbsp;</a><span>2020; 10(578):</span></p><h3><a href="http://sun.aei.polsl.pl/REFRESH/index.php?page=projects&amp;project=gdc&amp;subpage=about">GDC</a></h3><p><strong>Compressor of collections of genome sequences.</strong></p><p><span>&bull;&nbsp;&nbsp;Deorowicz, S., Danek, A., Niemiec, M.,&nbsp;</span><em>GDC 2: Compression of large collections of genomes</em><span>,&nbsp;</span><a href="http://www.nature.com/srep/2015/150625/srep11565/full/srep11565.html">Scientific Reports,&nbsp;</a><span>2015; 5(11565):1&ndash;12,</span><br /><span>&bull;&nbsp;&nbsp;Deorowicz, S., Grabowski, Sz.,&nbsp;</span><em>Robust relative compression of genomes with random access</em><span>,&nbsp;</span><a href="http://sun.aei.polsl.pl/REFRESH/bioinformatics.oxfordjournals.org/content/27/21/2979.abstract">Bioinformatics,&nbsp;</a><span>2011; 27(21):2979&ndash;2986,</span></p><h3><a href="http://sun.aei.polsl.pl/REFRESH/index.php?page=projects&amp;project=gtc&amp;subpage=about">GTC</a></h3><p><strong>Genotype databases compressor with support for fast queries.</strong></p><p><span>&bull;&nbsp;&nbsp;Danek, A., Deorowicz, S.,&nbsp;</span><em>GTC: how to maintain huge genotype collections in a compressed form</em><span>,&nbsp;</span><a href="https://doi.org/10.1093/bioinformatics/bty023">Bioinformatics,&nbsp;</a><span>2018; 34(11):1834&ndash;1840,</span></p><h3><a href="http://sun.aei.polsl.pl/REFRESH/index.php?page=projects&amp;project=gtshark&amp;subpage=about">GTShark</a></h3><p><strong>Genotypes compressor.</strong></p><p><span>&bull;&nbsp;&nbsp;Deorowicz, S., Danek, A.,&nbsp;</span><em>GTShark: Genotype compression in large projects</em><span>,&nbsp;</span><a href="https://doi.org/10.1093/bioinformatics/btz508">Bioinformatics,&nbsp;</a><span>2019; 35(22):4791&ndash;4793,</span></p><h3><a href="http://sun.aei.polsl.pl/REFRESH/index.php?page=projects&amp;project=kmc&amp;subpage=about">KMC</a></h3><p><strong>Memory frugal&nbsp;<em>k</em>-mer counter.</strong></p><p><span>&bull;&nbsp;&nbsp;Kokot, M., Długosz, M., Deorowicz, S.,&nbsp;</span><em>KMC 3: counting and manipulating k -mer statistics</em><span>,&nbsp;</span><a href="https://doi.org/10.1093/bioinformatics/btx304">Bioinformatics,&nbsp;</a><span>2017; 33(17):2759&ndash;2761,</span><br /><span>&bull;&nbsp;&nbsp;Deorowicz, S., Kokot, M., Grabowski, Sz., Debudaj-Grabysz, A.,&nbsp;</span><em>KMC 2: Fast and resource-frugal k-mer counting</em><span>,&nbsp;</span><a href="https://doi.org/10.1093/bioinformatics/btv022">Bioinformatics,&nbsp;</a><span>2015; 31(10):1569&ndash;1576,</span><br /><span>&bull;&nbsp;&nbsp;Deorowicz, S., Debudaj-Grabysz, A., Grabowski, Sz.,&nbsp;</span><em>Disk-based k-mer counting on a PC</em><span>,&nbsp;</span><a href="http://www.biomedcentral.com/1471-2105/14/160">BMC Bioinformatics,&nbsp;</a><span>2013; 14():Article no. 160,</span></p><h3><a href="http://sun.aei.polsl.pl/REFRESH/index.php?page=projects&amp;project=kmer-db&amp;subpage=about">Kmer-db</a></h3><p><strong>Tool for estimation of evolutionary distances in a collection of genomes.</strong></p><p><span>&bull;&nbsp;&nbsp;Deorowicz, S., Gudys, A., Dlugosz, M., Kokot, M., Danek, A.,&nbsp;</span><em>Kmer-db: instant evolutionary distance estimation</em><span>,&nbsp;</span><a href="https://doi.org/10.1093/bioinformatics/bty610">Bioinformatics,&nbsp;</a><span>2019; 35(1):133&ndash;136,</span></p><h3><a href="http://sun.aei.polsl.pl/REFRESH/index.php?page=projects&amp;project=mugi&amp;subpage=about">MuGI</a></h3><p><strong>Index allowing queries for a collection of multiple genome sequences.</strong></p><p><span>&bull;&nbsp;&nbsp;Danek, A., Deorowicz, S., Grabowski, Sz.,&nbsp;</span><em>Indexes of Large Genome Collections on a PC</em><span>,&nbsp;</span><a href="http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0109384">PLOS ONE,&nbsp;</a><span>2014; 9(10):e109384,</span></p><h3><a href="http://sun.aei.polsl.pl/REFRESH/index.php?page=projects&amp;project=orcom&amp;subpage=about">ORCOM</a></h3><p><strong>Experimental compressor of sequencing reads.</strong></p><p><span>&bull;&nbsp;&nbsp;Grabowski, Sz., Deorowicz, S., Roguski, L.,&nbsp;</span><em>Disk-based compression of data from genome sequencing</em><span>,&nbsp;</span><a href="http://bioinformatics.oxfordjournals.org/content/early/2014/12/22/bioinformatics.btu844.abstract">Bioinformatics,&nbsp;</a><span>2014; 31(9):1389&ndash;1395,</span></p><h3><a href="http://sun.aei.polsl.pl/REFRESH/index.php?page=projects&amp;project=pgsa&amp;subpage=about">PgSA</a></h3><p><strong>Index allowing queries for a collection of sequencing reads.</strong></p><p><span>&bull;&nbsp;&nbsp;Kowalski, T., Grabowski, Sz., Deorowicz, S.,&nbsp;</span><em>Indexing arbitrary-length k-mers in sequencing reads</em><span>,&nbsp;</span><a href="http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0133198">PLOS ONE,&nbsp;</a><span>2015; 10(7):1&ndash;16,</span></p><h3><a href="http://sun.aei.polsl.pl/REFRESH/index.php?page=projects&amp;project=quickprobs&amp;subpage=about">QuickProbs</a></h3><p><strong>Multiple sequence alignment designed especially for GPU.</strong></p><p><span>&bull;&nbsp;&nbsp;Gudys, A., Deorowicz, S.,&nbsp;</span><em>QuickProbs 2: towards rapid construction of high-quality alignments of large protein families</em><span>,&nbsp;</span><a href="http://www.nature.com/articles/srep41553">Scientific Reports,&nbsp;</a><span>2017; 7(41553):</span><br /><span>&bull;&nbsp;&nbsp;Gudys, A., Deorowicz, S.,&nbsp;</span><em>QuickProbs &ndash; A Fast Multiple Sequence Alignment Algorithm Designed for Graphics Processors</em><span>,&nbsp;</span><a href="http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0088901">PLOS ONE,&nbsp;</a><span>2014; 9(2):e88901,</span></p><h3><a href="http://sun.aei.polsl.pl/REFRESH/index.php?page=projects&amp;project=reckoner&amp;subpage=about">RECKONER</a></h3><p><strong>Read error corrector.</strong></p><p><span>&bull;&nbsp;&nbsp;Maciej Długosz, M., Deorowicz, S.,&nbsp;</span><em>RECKONER: read error corrector based on KMC</em><span>,&nbsp;</span><a href="https://academic.oup.com/bioinformatics/article-abstract/33/7/1086/2843893/RECKONER-read-error-corrector-based-on-KMC">Bioinformatics,&nbsp;</a><span>2017; 33(7):1086&ndash;1089,</span></p><h3><a href="http://sun.aei.polsl.pl/REFRESH/index.php?page=projects&amp;project=tgc&amp;subpage=about">TGC</a></h3><p><strong>Compressor of collections of genomes given in Variant Call Format (VCF) files.</strong></p><p><span>&bull;&nbsp;&nbsp;Deorowicz, S., Danek, A., Grabowski, Sz.,&nbsp;</span><em>Genome compression: a novel approach for large collections</em><span>,&nbsp;</span><a href="http://bioinformatics.oxfordjournals.org/content/early/2013/08/29/bioinformatics.btt460">Bioinformatics,&nbsp;</a><span>2013; 29(20):2572&ndash;2578,</span></p><h3><a href="http://sun.aei.polsl.pl/REFRESH/index.php?page=projects&amp;project=vcfshark&amp;subpage=about">VCFShark</a></h3><p><strong>Compressor of VCF files.</strong></p><p><span>&bull;&nbsp;&nbsp;Deorowicz, S., Danek, A.,&nbsp;</span><em>GTShark: Genotype compression in large projects</em><span>,&nbsp;</span><a href="https://www.biorxiv.org/content/10.1101/2020.12.18.423437v1">biorxiv.org,&nbsp;</a><span>2020; ():</span></p><h3><a href="http://sun.aei.polsl.pl/REFRESH/index.php?page=projects&amp;project=whisper&amp;subpage=about">Whisper</a></h3><p><strong>Experimental mapper of whole genome sequencing data.</strong></p><p><span>&bull;&nbsp;&nbsp;Deorowicz, S., Gudys, A.,&nbsp;</span><em>Whisper 2: indel-sensitive short read mapping</em><span>,&nbsp;</span><a href="https://doi.org/10.1101/2019.12.18.881292">bioRxiv.org,&nbsp;</a><span>2019; :</span><br /><span>&bull;&nbsp;&nbsp;Deorowicz, S., Debudaj-Grabysz, A., Gudys, A., Grabowski, Sz.,&nbsp;</span><em>Whisper: read sorting allows robust robust mapping of DNA sequencing data</em><span>,&nbsp;</span><a href="https://doi.org/10.1093/bioinformatics/bty927">Bioinformatics,&nbsp;</a><span>2019; 35(12):2043&ndash;2050,</span><br /><span>&bull;&nbsp;&nbsp;Deorowicz, S., Debudaj-Grabysz, A., Gudys, A., Grabowski, Sz.,&nbsp;</span><em>Robust mapping of whole genome sequencing data</em><span>,&nbsp;</span><a href="https://meetings.cshl.edu/abstracts.aspx?meet=GENOME&amp;year=17">Poster at The Biology of Genomes Conference,&nbsp;</a><span>2017;</span></p>]]></description>
	<dc:creator>Neel</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/videolist/watch/5380/04-informatics-approach-to-cancer-interview-with-dr-joel-saltz</guid>
	<pubDate>Mon, 07 Oct 2013 14:35:43 -0500</pubDate>
	<link>https://bioinformaticsonline.com/videolist/watch/5380/04-informatics-approach-to-cancer-interview-with-dr-joel-saltz</link>
	<title><![CDATA[04- Informatics Approach to Cancer - Interview with Dr. Joel Saltz]]></title>
	<description><![CDATA[<iframe width="" height="" src="https://www.youtube-nocookie.com/embed/8Kf5EP4LY7k" frameborder="0" allowfullscreen></iframe>For additional information visit http://www.cancerquest.org/joel-saltz-interview.

Dr. Joel Saltz is a Professor in the Departments of Pathology, Biostatistics and Bioinformatics, and Mathematics and Computer Science at
Emory University. Dr. Saltz's research on bioinformatics spans several disciplines.  One project involves applying computer analysis to medical imaging to yield better results for patients.  As an example, a computer program may able to help doctors detect small cancers in a CT scan or mammogram. 

In this interview segment, Dr. Saltz  discusses the informatics approach to cancer.

To learn more about cancer and watch additional interviews, please visit the CancerQuest website at http://www.cancerquest.org.]]></description>
	
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	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/44002/interesting-bioinformatics-resources</guid>
	<pubDate>Fri, 11 Nov 2022 06:30:46 -0600</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/44002/interesting-bioinformatics-resources</link>
	<title><![CDATA[Interesting Bioinformatics Resources !]]></title>
	<description><![CDATA[<p>1. a reproducible workflow.&nbsp;<a href="https://www.youtube.com/watch?v=s3JldKoA0zw">https://www.youtube.com/watch?v=s3JldKoA0zw</a>&nbsp;This two minute video will change your mind on reproducible research&nbsp;</p><p>2. Parallel sequencing lives, or what makes large sequencing projects successful&nbsp;<a href="https://academic.oup.com/gigascience/article/6/11/gix100/4557140?login=false">https://academic.oup.com/gigascience/article/6/11/gix100/4557140?login=false</a></p><p>3. Common-sense approaches to sharing tabular data alongside publication&nbsp;<a href="https://www.sciencedirect.com/science/article/pii/S2666389921002300">https://www.sciencedirect.com/science/article/pii/S2666389921002300</a></p><p>4. A Reproducible Data Analysis Workflow with R Markdown, Git, Make, and Docker&nbsp;<a href="https://psyarxiv.com/8xzqy/">https://psyarxiv.com/8xzqy/</a></p><p>5. Practical Computational Reproducibility in the Life Sciences&nbsp;<a href="https://www.cell.com/cell-systems/fulltext/S2405-4712(18)30140-6">https://www.cell.com/cell-systems/fulltext/S2405-4712(18)30140-6</a></p><p>6. A video by Dr.Keith A. Baggerly from MD Anderson [The Importance of Reproducible Research in High-Throughput Biology](<a href="https://www.youtube.com/watch?v=7gYIs7uYbMo">https://www.youtube.com/watch?v=7gYIs7uYbMo</a>) highly recommended.</p><p>7. Ten Simple Rules for Reproducible Computational Research&nbsp;<a href="http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1003285">http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1003285</a>)</p><p>8. Good Enough Practices in Scientific Computing&nbsp;<a href="http://arxiv.org/abs/1609.00037">http://arxiv.org/abs/1609.00037</a>&nbsp;</p><p>9. Best Practices for Scientific Computing&nbsp;<a href="https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1001745">https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1001745</a></p><p>10. A Quick Guide to Organizing Computational Biology Projects&nbsp;<a href="http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.100042">http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.100042</a>&nbsp; A must read for computational biologists!</p><p>11. Reproducibility of computational workflows is automated using continuous analysis&nbsp;<a href="https://www.nature.com/articles/nbt.3780">https://www.nature.com/articles/nbt.3780</a></p><p>12. Five selfish reasons to work reproducibly&nbsp;<a href="https://genomebiology.biomedcentral.com/articles/10.1186/s13059-015-0850-7">https://genomebiology.biomedcentral.com/articles/10.1186/s13059-015-0850-7</a></p>]]></description>
	<dc:creator>Abhi</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/videolist/watch/4959/evolution-and-cancer</guid>
	<pubDate>Fri, 27 Sep 2013 11:28:49 -0500</pubDate>
	<link>https://bioinformaticsonline.com/videolist/watch/4959/evolution-and-cancer</link>
	<title><![CDATA[Evolution and Cancer]]></title>
	<description><![CDATA[<iframe width="" height="" src="https://www.youtube-nocookie.com/embed/j3uKOcNwYBw" frameborder="0" allowfullscreen></iframe>Air date:  Wednesday, January 04, 2012, 3:00:00 PM
Time displayed is Eastern Time, Washington DC Local  
 
Category:  Wednesday Afternoon Lectures  
Description:  There is a broad consensus that cancer is the result of somatic cells having serially gained, by a series of mutations, the ability to grow independently, to recruit resources from the circulation and the stroma, to invade local tissues, and to found anatomically distant metastases, ultimately killing the host. From the point of view of the cancer-causing somatic cell population, this is evolution driven by mutation and selection. Genomics has resulted in a parallel consensus that the central functions of all eukaryotes are highly conserved, not only at the level of individual protein functions, but also complex biological pathways and systems. These ideas motivated a comparison between results of molecular genetic studies of experimental evolution in yeast and the molecular genetic phenomena associated with tumorigenesis and tumor progression. We find some very striking similarities, including recurring genomic rearrangements, alterations of the regulation of specific growth-promoting genes, population-genetic features that affect the fitness trajectories of growth rate variants in evolving populations, and physiological and metabolic similarities derived from the conservation of the basic plan of growth and cell multiplication among all eukaryotes. It is hoped that some of the insights from yeast will aid the interpretation of sequence changes found in tumors, especially in the urgent necessity to distinguish 'driver' from 'passenger' mutations." 

David Botstein's fundamental contributions to modern genetics include the development of genetic methods for understanding biological functions and the discovery of the functions of many yeast and bacterial genes. In 1980, Botstein and three colleagues proposed a method for mapping human genes that laid the groundwork for the Human Genome Project. The basic principle of the mapping scheme was to develop, by recombinant DNA techniques, random single-copy DNA probes capable of detecting DNA sequence polymorphisms when hybridized to restriction digests, or specific fragments, of an individual's DNA. The method was used in subsequent years to identify several human disease genes, such as Huntington's and BRCA1. Variations of this method enabled the sequencing phase of the Human Genome Project. 

In the 1990s Botstein, having moved to Stanford University School of Medicine, collaborated with Patrick O. Brown of Stanford in exploiting DNA microarrays to study genome-wide gene expression patterns in yeast and in human cancers. This required developing a new statistical method and graphical interface, widely used today to interpret genomic data. Botstein also has helped to create, with Michael Ashburner and Gerald Rubin, a bioinformatics initiative to unify the representation of gene and gene product attributes across all species, called Gene Ontology. He graduated from Harvard College and earned his doctorate from the University of Michigan. He worked at Massachusetts Institute of Technology from 1967 to 1988; served as vice president for science at Genentech from 1988 to 1990; chaired the Department of Genetics at the Stanford University School of Medicine from 1990 to 2003; and joined the Princeton University faculty in 2003. He has sat on numerous editorial boards and was the founding editor of Molecular Biology of the Cell. Among recent major awards, Bostein won the Peter Gruber Foundation Prize in Genetics in 2003, the Apple Science Innovator Award in 2008, and the Albany Medical Center Prize in 2010. 

The NIH Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide. 

For more information, visit: The NIH Director's Wednesday Afternoon Lecture Series  
Author:  Dr. David Botstein, Princeton University  
Runtime:  00:59:58  

Permanent link:  http://videocast.nih.gov/launch.asp?17046]]></description>
	
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