“It’s like a subway map,” she said, “but for DNA.”

That idea is exactly what Sequence Tube Map brings to life.

Instead of showing a genome as one long, confusing sequence, it displays different genomic paths like routes on a metro map. Where sequences are shared, the paths travel together. Where genetic variation occurs, they branch into different routes and may join again later.

This makes complex genome graphs much easier to explore.

Maya could now see how different haplotypes moved through the same genomic region and where they took different paths. She could even view sequencing reads mapped onto the graph, helping her understand what was happening in regions with genetic variation.

What once looked like a tangled network now looked like a journey.

Sequence Tube Map turns the complexity of graph genomes into a visual story—making it easier for scientists to see how DNA can take different routes.

Read more at  https://github.com/vgteam/sequencetubemap 

and

https://academic.oup.com/bioinformatics/article/35/24/5318/5542397

Demo at https://vgteam.github.io/sequenceTubeMap/

Pay Scale: Rs. 40,000/-per month +HRA (as admissible) for Ph.D. holders and Rs. 38,000/-p.m. + HRA (as admissible) for Master degree holder

Qualifications: a)Essential :

Ph.D.in Biotechnology/ Molecular B iology/ Genetics & Plant Breeding/ Bioinformatics ( Should have the degree in life sciences at gra duate level) OR Post - Graduation in Biotechnology/ Molecular Biology/ Bioinformati cs/Genetics & Plant Breeding

or equivalent with at least two years of research experience and 60% marks. ( should have a degree in life sciences at graduate level)

b) Desirable :

1. Working experience in plant molecular biology

2. Knowledge of Computational Genomics/Proteomics/ Bioinformatics

3. Working knowledge on Computer programming

Walk-in Interview will be held at The Indian Institute of Spices Research, Marikunnu P.O., Kozikode-673012, Kerala on 28/7/2015 at 10.00 AM.

For more details: http://www.spices.res.in/pdf/Mining%20and%20Validation%20Website.pdf

Instead of asking only whether two genes occur together across genomes, CORGIAS asks a deeper question: did these genes actually evolve together, repeatedly gaining or losing their presence in concert, or are they merely travelling together because of their inherited history? The framework introduces two complementary approaches, Ancestral State Adjustment (ASA) and the Simultaneous EVolution test (SEV), which incorporate evolutionary information into the search for gene associations. This distinction becomes increasingly important as genome sequencing continues to uncover enormous numbers of microbial genomes, many from organisms that have never been cultured and whose genes remain functionally mysterious. In this growing genomic landscape, simply finding a gene is no longer enough—we need clues about what that gene might be doing. CORGIAS approaches this problem almost like a genomic detective: rather than treating every association as evidence, it reconstructs the evolutionary story behind the association and asks whether the evidence survives that history. By doing so, it offers a way to separate coincidence from biological connection and potentially uncover functional relationships hidden within the vast microbial genomic landscape. The broader message is beautifully simple: genes do not evolve in isolation, and understanding what they do may require us to look beyond where they are today and reconstruct how they arrived there. Sometimes, the most important clue in a genome is not the gene itself, but the evolutionary journey it has taken.

More at https://academic.oup.com/nargab/article/7/4/lqaf182/8377910?

Desirable qualification: M.Sc (Life Sciences) with Bioinformatics knowledge and hands on molecular biology tools.

Age: Not exceeding 30 years on the last date of receipt of application

Job work: Molecular modelling studies, Database curation, Metagenomic studies on Dengue virus

Advertisement: http://vcrc.res.in/writereaddata/BIPrj15.pdf

Is this available, or still under trial mode? 

https://www.nanoporetech.com/

https://www.nanoporetech.com/technology/the-minion-device-a-miniaturised-sensing-system/the-minion-device-a-miniaturised-sensing-system

WALK-IN-INTERVIEW (EMPLOYMENT NOTIFICATION)

Eligible candidates are invited to apply for the following post on the ad hoc research project entitled “Biomedical Informatics Centre’s of ICMR” - funded by ICMR at this Institute. The Applications will be received from the individuals on 31st July, 2015 between 9:30 A.M. and 10:30 A.M. at Conference Hall, NIN, Tarnaka, Hyderabad.

Late applications will not be entertained after 10:30 A.M. at any circumstances.

The Candidates may download the Application Form from NIN website: www.ninindia.org

Selection Procedure: Written test and Interview will be conducted to the eligible candidates, if the large numbers of candidates are found to be eligible in the screening. If the lesser number of candidates are found to be eligible in the screening, interview will be conducted only to the short listed candidates for final selection. The names of the shortlisted candidates will be displayed on the Notice Board, which is kept in front of the Conference Hall by 11:30 A.M.

Date of Written Test / Interview: 31st July, 2015. The essential qualification, experience, consolidated Pay and service tenure are as under:

1. Scientist-II (no. of vacancies -1 No.) (UR)

Essential Qualifications :

(i) First Class Master’s Degree in Bio-informatics/ Life Sciences form a recognized University with 4 years R&D experience in the biomedical informatics subject. (or)

(ii) 2nd Class M.Sc./ M.Tech. in Bio-informatics + Ph.D. in the relevant subject from recognized University with 4 years research experience in the biomedical informatics subject.

Age limit : Not exceeding 40 years. Cons.

Pay : Rs.45,954/- p.m. plus 30% HRA p.m. (fixed) without any other allowances.

Tenure : Initially upto 29th February, 2016 and extendable for three more years based on the performance of the candidate and funds position.

Note: Age relaxation will be given to the deserving Candidates. The short listed candidates should bring all original certificates of educational qualification (from SSC onwards), experience, SC/ST/OBC Community Certificate / PH Certificates along with a pass port size photograph and set of Photo copies duly attested for attending the Written Test/Interview. The persons belonging to Other Backward Category should bring the latest O.B.C. (Non-creamy layer) Certificate issued by the respective Tahsildar/ MRO specifically issued for the purpose of applying for Central Government Post. No TA/DA will be paid for attending the Written Test /Interview.

GENERAL CONDITIONS: The conditions of employment will be the same as are for the project staff on contract basis. The candidates have no right to claim for any regular employment at this Institute. The Director In-charge & Appointing Authority has the right to accept / reject any application without assigning any reason/s and no correspondence in this matter will be entertained.

More at http://ninindia.org/31July2015.pdf

Our main advantages over other similar tools are:

• GeneAnalytics is very simple and intuitive to use.
• GeneAnalytics is based on our proprietary databases – GeneCards, MalaCards, PathCards and LifeMap Discovery, each of them integrates information from a very large number of resources.
• GeneAnalytics supplies links for extensive background information on each of the matched results.

I invite you to try it out for free at geneanalytics.genecards.org, and would be happy to hear your comments and thoughts on how we can improve.

Yours,

Shani Ben-Ari Fuchs

LifeMap Sciences Team

In fact, there are huge demands for expert biological data analyst. It’s a fairly new  (not exactly) hot area, these bioinformatician are invaluable because they know and understand the significance of biological data for your research and how you can use it for better understanding of biological problems.

The bioinformatics can discover biological patterns and stories in genomic and proteomics data. They can develop the pipeline needed to properly collect, store and analyse it.

Once your research group is ready to make a larger investment and hire a bioinformatician to gain a competitive edge, there are several key traits to seek out in potential candidates. The best bioinformatician are:

1. Highly Skilled - programming skills, experience with the biological software and tools.

The biological data won’t illuminate much if the scientist analysing it doesn’t possess practical programming skills, experience with the biological software and tools and a thorough understanding of basic biological stuff. A solid background in mathematics and statistics is also an indispensable trait.

2. Insight - Real vision, robust understanding and deep insight.

In order to hire the best bioinformatics and computational biologist scientist for your needs, it is always recommended and mostly practiced by the recruiters, to ask each contender to write and develop a sample script/presentation based on a specific set of data you provide. Then, explore the approaches used to deal with data provided and pick up those candidates who convey real vision, robust understanding and deep insight.

3. Energetic – Curiosity to explore

Mostly natural curiosity and enthusiasm for solving big biological problems coupled with an ability to transform data into a scientific stories may place one candidate above the rest. In addition to achieve that, the bioinformatician should be agile enough to quickly modify their methods to suit changes within a particular research.

4. Researcher – Publications

Look for someone who has a keen sense and understanding of concern biological problems. You can judge it by looking at previously published papers and data. It is always recommended to have a look at GitHub and other repository for codes written by her/him.

5. Impressive communicator - Insight that can’t be expressed is worthless.

Good bioinformatics scientists are able to uncover biological patterns and are willing to explain those patterns in clear and helpful ways through thoughtful and open communication. In other words, they should must have good scientific writing skills. A computational biologis/bioinformatician  should know how to present the data and tell a scientific story through numbers/images.

Address of the bookmark: https://bernatgel.github.io/karyoploter_tutorial/

Applications are invited for one JRF position supported by DST sponsored project in Bioinformatics with Dr. Tarun Kumar Bhatt.

Title of the project: Molecular Modeling of malaria parasite ‘secretome’: A potential drug target

Fellowship: Rs. 14000 consolidated

Duration of project: 36 months.

Essential Qualification: Master’s degree in Biotechnology/Bioinformatics with minimum 55% marks. Age limit as per government rule.

Candidates with good experience of molecular modeling, In-silico screening, MD simulation and database formation will be preferred. Good knowledge of Linux operating system is desirable.

How to apply: Interested candidate can send soft copy of application in format given below to tarun@curaj.ac.in on or before 29/08/2015.

1. Name
2. Fathers name
3. Date of Birth
5. Age
6. Sex
7. Address
8. Telephone / mobile no.
9. Email:
10. Academic qualifications starting from 10th class.
11. Summary of experience in molecular modeling, In-silico screening and database formation.

General Conditions:

1.Selected candidate would be informed for date and time of the interview via email .
2. No TA/DA will be paid for attending the interview.

More at http://www.curaj.ac.in/2015/Rec/aug/Advertisement%20for%20post%20of%20JRF%20under%20DST%20project%28BioTech%29.pdf