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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/28566?offset=20</link>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/914/welch-lab</guid>
  <pubDate>Mon, 15 Jul 2013 18:21:13 -0500</pubDate>
  <link></link>
  <title><![CDATA[Welch Lab]]></title>
  <description><![CDATA[
<p>They are based in the Department of Genetics at the University of Cambridge. </p>

<p>The research covers diverse areas of evolutionary biology, and molecular evolution in particular. It combines theoretical and empirical approaches, and particularly evolutionary inference from genome sequence data.</p>

<p>Links @ http://www.gen.cam.ac.uk/research/welch/GroupPage/Home.html</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/32465/tetra-nucleotide-analysis</guid>
	<pubDate>Thu, 04 May 2017 05:07:41 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/32465/tetra-nucleotide-analysis</link>
	<title><![CDATA[Tetra-Nucleotide Analysis]]></title>
	<description><![CDATA[<p>A tetra-nucleotide is a fragment of DNA sequence with 4 bases (e.g. AGTC or TTGG). Pride&nbsp;<em>et al.</em>&nbsp;(2003) showed that the frequency of tetra-nucleotides in bacterial genomes contain useful, albeit weak, phylogenetic signals. Even though tetra-nucleotide analysis (TNA) utilizes the information of whole genome, it is evident that it cannot replace other alignment-based phylogenetic methods such as&nbsp;<a href="https://chunlab.wordpress.com/orthoani/">OrthoANI</a>&nbsp;or&nbsp;16S rRNA phylogeny. However, TNA can be useful for&nbsp;phylogenetic characterization when whole genome or 16S rRNA gene information is not available. For example, a partial genomic fragment obtained from a metagenome can be identified by TNA (Teeling&nbsp;<em>et al.</em>, 2004). TNA is also fast enough that it can be&nbsp;used&nbsp;as a search engine against a large genome database.</p><p>Address of the bookmark: <a href="https://chunlab.wordpress.com/tetra-nucleotide-analysis/" rel="nofollow">https://chunlab.wordpress.com/tetra-nucleotide-analysis/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/926/list-of-popular-bioinformatics-softwaretools</guid>
	<pubDate>Tue, 16 Jul 2013 14:30:30 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/926/list-of-popular-bioinformatics-softwaretools</link>
	<title><![CDATA[List of popular bioinformatics software/tools]]></title>
	<description><![CDATA[<p><a href="http://samtools.sourceforge.net/swlist.shtml">I</a>n current genome era, our day to day work is to handle the huge geneome sequences, expression data, several other datasets. This link provide a comprehensive list of commonly used sofware/tools.</p><p>Address of the bookmark: <a href="http://samtools.sourceforge.net/swlist.shtml" rel="nofollow">http://samtools.sourceforge.net/swlist.shtml</a></p>]]></description>
	<dc:creator>Jitendra Narayan</dc:creator>
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<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/32496/bioinformatician-at-23andme</guid>
  <pubDate>Sat, 06 May 2017 17:57:39 -0500</pubDate>
  <link></link>
  <title><![CDATA[Bioinformatician at 23andMe]]></title>
  <description><![CDATA[
<p>23andMe’s mission is to help people access, understand, and benefit<br />from the human genome. We are a group of passionate individuals excited<br />to push the boundaries of what’s possible to help turn genetic insight<br />into better health and personal understanding.</p>

<p>Our Research Team prides itself on driving cutting edge, industrial-scale<br />science to make an impact that belies the team’s size, in an environment<br />and culture that fosters creativity, innovation, collaboration, and fun.</p>

<p>More than 80% of our customers consent to participate in research, and as<br />a result of their participation, we have one of the largest recontactable,<br />genotyped, and phenotyped research cohorts in the world. The scope and<br />breadth of our vision means that most of the methods and tools necessary<br />to unlock the potential of this unique resource for discovery have yet<br />to be developed.</p>

<p>Our science has garnered the respect of many members of the<br />broader scientific community. For a list of our publications, see<br />www.23andme.com/publications/for-scientists/.</p>

<p>Join us! Visit our Careers page (www.23andMe.com/careers) to learn more<br />about these open positions:</p>

<p>•	Scientist, Research Communications<br />•	Bioinformaticist<br />•	Computational Biologist, Ancestry R&amp;D<br />•	Scientist/Senior Scientist, Statistical Genetics<br />•	Scientist/Senior Scientist, Survey Methodology<br />•	Scientist/Senior Scientist, Health R&amp;D<br />•	Senior Computational Biologist<br />•	Biostatistician</p>

<p>pfontanillas@23andme.com</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/1212/computational-proteomics-lets-remember-the-basics</guid>
	<pubDate>Thu, 01 Aug 2013 17:24:20 -0500</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/1212/computational-proteomics-lets-remember-the-basics</link>
	<title><![CDATA[Computational Proteomics : Lets remember the basics]]></title>
	<description><![CDATA[<p>I spend some of my valuable time in computational drug designing sector. I remember my initial proteomics days, playing with interactive protein visualization software and dreaming big. Fortunately or unfortunately, I switched to genomics and handling the genomic floods in Petabytes which is expected to be in Brontobytes in coming years. Did I mention Brontobytes ??? Let me call to my server personnel &hellip; it gonna tsunami !!!!!</p><p>Today, refreshing my old memories I decided to blog about the basic knowledge of biochemistry and computational proteomics&nbsp;skills, but after I found several article on internet saying exactly what I had wanted to say I thought I might as well just redirect BOL's blog readers there instead:</p><p>Here is the list of website and videos links which provide a good resource for you basic chemistry need:</p><p><a href="http://tecreativ.blogspot.co.uk/2012/09/funny-shortcut-remember-periodic-table.html"></a><a href="http://tecreativ.blogspot.co.uk/2012/09/funny-shortcut-remember-periodic-table.html"></a><a href="http://tecreativ.blogspot.co.uk/2012/09/funny-shortcut-remember-periodic-table.html"></a><a href="http://tecreativ.blogspot.co.uk/2012/09/funny-shortcut-remember-periodic-table.html">http://tecreativ.blogspot.co.uk/2012/09/funny-shortcut-remember-periodic-table.html</a></p><p>This blog have some specific hindi word to remember entire periodic table. I really like</p><p>Group 14 (C Si Ge Sn Pb) -&gt; Sentence &ldquo;<strong>C</strong>hemistry&nbsp;<strong>Si</strong>r&nbsp;<strong>G</strong>iv<strong>e</strong>s&nbsp;<strong>S</strong>a<strong>n</strong>ki&nbsp;<strong>P</strong>ro<strong>b</strong>lems&rdquo;</p><p>Sanki is a hindi word which mean crazy :P</p><p>I found this link useful as well&nbsp;<a href="http://www.wikihow.com/Memorise-the-Periodic-Table"></a><a href="http://www.wikihow.com/Memorise-the-Periodic-Table"></a><a href="http://www.wikihow.com/Memorise-the-Periodic-Table"></a><a href="http://www.wikihow.com/Memorise-the-Periodic-Table">http://www.wikihow.com/Memorise-the-Periodic-Table</a></p><p>The eagle genomics group provide an element of bioinformatics in periodic tables. Yes you got it, this is not periodic table rather bioinformatics tools with periodicals</p><p><a href="http://elements.eaglegenomics.com/"></a><a href="http://elements.eaglegenomics.com/"></a><a href="http://elements.eaglegenomics.com/"></a><a href="http://elements.eaglegenomics.com/">http://elements.eaglegenomics.com/</a></p><p>You can also try this video links, which provide you an overview with tricks on periodic tables:</p><p><a href="http://www.youtube.com/watch?v=fLSfgNxoVGk"></a><a href="http://www.youtube.com/watch?v=fLSfgNxoVGk"></a><a href="http://www.youtube.com/watch?v=fLSfgNxoVGk"></a><a href="http://www.youtube.com/watch?v=fLSfgNxoVGk">http://www.youtube.com/watch?v=fLSfgNxoVGk</a></p><p><a href="http://www.youtube.com/user/periodicvideos"></a><a href="http://www.youtube.com/user/periodicvideos"></a><a href="http://www.youtube.com/user/periodicvideos"></a><a href="http://www.youtube.com/user/periodicvideos">http://www.youtube.com/user/periodicvideos</a></p><p>For drug design educational material, software, tools, databses, viewer, file format and many more stuff at one place&nbsp;<a href="http://www.allfordrugs.com/drug-design/.%C2%A0I"></a><a href="http://www.allfordrugs.com/drug-design/"></a><a href="http://www.allfordrugs.com/drug-design/"></a><a href="http://www.allfordrugs.com/drug-design/">http://www.allfordrugs.com/drug-design/</a>&nbsp;I highly recommend you all computational drug designer to bookmark this page for future studies as well.</p><p>I just remember one of my mini project in which I use my flash knowledge (flash .. oh ya flash) to explain amino acids in interactive and user friendly manner. I can&rsquo;t provide It right now, but promise you to provide a link in near future. I hope that you will enjoy my flashy creative skills :).</p><p>Moreover, I found some of very interesting tricks to remember all amino acids chemical formulae on youtube at</p><p><a href="http://www.youtube.com/watch?v=gqrWb0fmzQ&amp;list=PL6132651E70BB5575"></a><a href="http://www.youtube.com/watch?v=gqrWb0fmzQ&amp;list=PL6132651E70BB5575"></a><a href="http://www.youtube.com/watch?v=gqrWb0fmzQ&amp;list=PL6132651E70BB5575"></a><a href="http://www.youtube.com/watch?v=gqrWb0fmzQ&amp;list=PL6132651E70BB5575">http://www.youtube.com/watch?v=gqrWb0fmzQ&amp;list=PL6132651E70BB5575</a></p><p><a href="http://www.youtube.com/watch?v=C2GfoGXfySQ&amp;list=PL6132651E70BB5575"></a><a href="http://www.youtube.com/watch?v=C2GfoGXfySQ&amp;list=PL6132651E70BB5575"></a><a href="http://www.youtube.com/watch?v=C2GfoGXfySQ&amp;list=PL6132651E70BB5575"></a><a href="http://www.youtube.com/watch?v=C2GfoGXfySQ&amp;list=PL6132651E70BB5575">http://www.youtube.com/watch?v=C2GfoGXfySQ&amp;list=PL6132651E70BB5575</a></p><p><br />Key points for computer added drug designers?<br />1. A shortage of biochemistry skills means that you absolutely nowhere in understanding the key concept and do research.<br />2. Keep handy with complex mathematical formula, before merely running tools or software.<br />3. Dig it better and deeper guys .. design it.</p>]]></description>
	<dc:creator>Jitendra Narayan</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/32633/a-post-assembly-genome-improvement-toolkit-pagit-to-obtain-annotated-genomes-from-contigs</guid>
	<pubDate>Fri, 12 May 2017 10:50:29 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/32633/a-post-assembly-genome-improvement-toolkit-pagit-to-obtain-annotated-genomes-from-contigs</link>
	<title><![CDATA[A Post-assembly genome-improvement toolkit (PAGIT) to obtain annotated genomes from contigs]]></title>
	<description><![CDATA[<p>PAGIT addresses the need for software to generate high quality draft genomes. It is based on a series of programs that we developed:</p>
<p><a href="https://sourceforge.net/projects/abacas/files/">ABACAS</a>, that is able to contiguate contigs from a de novo assembly against a closely related reference.</p>
<p><a href="https://sourceforge.net/projects/image2/files/">IMAGE</a>, an iterative approach for closing gaps in assembled genomes using mate pair information. It is able to close gaps left open by the assembler in a draft genome, even when using the same data sets as used by the original assembler.</p>
<p><a href="http://icorn.sourceforge.net/">iCORN</a>, that enables errors in the consensus sequence to be corrected by iteratively mapping reads to the current assembly. An improved version, especially correction Pacfic Bioscience assemblies (PacBio) can be found&nbsp;<a href="ftp://ftp.sanger.ac.uk/pub4/resources/software/pagit/ICORN2/icorn2.V0.95.tgz">here</a>.</p>
<p><a href="https://ratt.svn.sourceforge.net/svnroot/ratt">RATT</a>, a tool to transfer the annotation from a reference genome, or an earlier assembly, onto the latest assembly.</p>
<p>PAGIT bundles these software and makes them more accessible for users.</p><p>Address of the bookmark: <a href="http://www.sanger.ac.uk/science/tools/pagit" rel="nofollow">http://www.sanger.ac.uk/science/tools/pagit</a></p>]]></description>
	<dc:creator>Abhimanyu Singh</dc:creator>
</item>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/file/view/2780/life-of-bi</guid>
	<pubDate>Thu, 22 Aug 2013 16:13:36 -0500</pubDate>
	<link>https://bioinformaticsonline.com/file/view/2780/life-of-bi</link>
	<title><![CDATA[Life of BI !!!]]></title>
	<description><![CDATA[<p>Hmm .. Don't worry you read it right .. this is not pi but bi ... "life of Bioinformatician(BI)".&nbsp;</p><p><span>Disclaimer:</span>&nbsp;This cartoon is solely designed to create humour and fun, not to offend any PI, supervisor or student.</p>]]></description>
	<dc:creator>Jitendra Narayan</dc:creator>
	<enclosure url="https://bioinformaticsonline.com/file/download/2780" length="63826" type="image/jpeg" />
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	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/32719/download-assemblies-from-ncbi</guid>
	<pubDate>Mon, 15 May 2017 06:02:32 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/32719/download-assemblies-from-ncbi</link>
	<title><![CDATA[Download assemblies from NCBI]]></title>
	<description><![CDATA[<p>A new &ldquo;Download assemblies&rdquo; button is now available in the&nbsp;<a href="https://www.ncbi.nlm.nih.gov/assembly" target="_blank">Assembly</a>&nbsp;database. This makes it easy to download data for multiple genomes without having to write scripts.</p><p>For example, you can run a search in Assembly and use check boxes (see left side of screenshot below) to refine the set of genome assemblies of interest. Then, just open the &ldquo;Download assemblies&rdquo; menu, choose the source database (<a href="https://www.ncbi.nlm.nih.gov/genbank/" target="_blank">GenBank</a>&nbsp;or&nbsp;<a href="https://www.ncbi.nlm.nih.gov/refseq/" target="_blank">RefSeq</a>), choose the file type, and start the download. An archive file will be saved to your computer that can be expanded into a folder containing your selected genome data files.</p><p><img src="https://ncbiinsights.files.wordpress.com/2017/05/download_button.jpg?w=584" alt="image" width="584" height="444" style="border: 0px; border: 0px;"></p><p>&nbsp;</p><p>More at&nbsp;https://ncbiinsights.ncbi.nlm.nih.gov/2017/05/08/genome-data-download-made-easy/</p>]]></description>
	<dc:creator>Bulbul</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/2041/uk-genome-science-meeting-sept-2nd-4th-2013</guid>
	<pubDate>Mon, 12 Aug 2013 12:03:21 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/2041/uk-genome-science-meeting-sept-2nd-4th-2013</link>
	<title><![CDATA[UK Genome Science Meeting, sept 2nd-4th, 2013]]></title>
	<description><![CDATA[<p>Following the success of the last three years' UK Next Gen Sequencing meetings at Nottingham, the newly named UK Genome Science meeting aims to bring together experts from around the world to meet and discuss the current and future state of all aspects and applications of Next Generation Sequencing.</p><p>More at &gt;&gt;&nbsp;<a href="http://www.nottingham.ac.uk/deepseq/events.aspx">http://www.nottingham.ac.uk/deepseq/events.aspx</a></p>]]></description>
	<dc:creator>Poonam Mahapatra</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/32849/car-reconstructing-contiguous-regions-of-an-ancestral-genome</guid>
	<pubDate>Thu, 18 May 2017 05:24:01 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/32849/car-reconstructing-contiguous-regions-of-an-ancestral-genome</link>
	<title><![CDATA[CAR: Reconstructing Contiguous Regions of an Ancestral Genome]]></title>
	<description><![CDATA[<div id="abstract-1">
<p id="p-5">We describe a new method for predicting the ancestral order and orientation of those intervals from their observed adjacencies in modern species. We combine the results from this method with data from chromosome painting experiments to produce a map of an early mammalian genome that accounts for 96.8% of the available human genome sequence data. The precision is further increased by mapping inversions as small as 31 bp. Analysis of the predicted evolutionary breakpoints in the human lineage confirms certain published observations but disagrees with others. Although only a few mammalian genomes are currently sequenced to high precision, our theoretical analyses and computer simulations indicate that our results are reasonably accurate and that they will become highly accurate in the foreseeable future. Our methods were developed as part of a project to reconstruct the genome sequence of the last ancestor of human, dogs, and most other placental mammals;</p>
</div><p>Address of the bookmark: <a href="http://www.bx.psu.edu/miller_lab/car/" rel="nofollow">http://www.bx.psu.edu/miller_lab/car/</a></p>]]></description>
	<dc:creator>Abhimanyu Singh</dc:creator>
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