<![CDATA[BOL: Related items]]> https://bioinformaticsonline.com/related/2882?offset=160 https://bioinformaticsonline.com/researchlabs/view/44400/pevzner-lab Thu, 02 Nov 2023 05:39:26 -0500 <![CDATA[Pevzner Lab !]]> The laboratory works on genome sequencing, immunoproteogenomics, antibiotics sequencing, and comparative genomics - computational technologies that enabled new applications and allowed scientists to attack biological problems that remained beyond the reach of previous techniques.

https://bioalgorithms.ucsd.edu/research4.html

]]> https://bioinformaticsonline.com/news/view/6302/a-allele-of-slc24a5-gene-is-found-to-be-responsible-for-variation-in-skin-color-of-south-east-asians-and-europeans Tue, 12 Nov 2013 21:02:27 -0600 https://bioinformaticsonline.com/news/view/6302/a-allele-of-slc24a5-gene-is-found-to-be-responsible-for-variation-in-skin-color-of-south-east-asians-and-europeans <![CDATA[A-allele of SLC24A5 gene is found to be responsible for variation in skin color of South-East Asians and Europeans]]> Key finding:

  1. rs1426654 SNP of SLC24A5 gene is decider of skin pigmentation variation in South Asia
  2. rs1426654-A allele is widely spread throughout the Indian subcontinent 
  3. Skin pigmentation is also account by the combination of processes like selection and demographic history of populations affected by their language and origin
  4. Sign of positive selection in Europeans, Middle East, Pakistan, Central Asia and North India but not in South India
  5. In European , A-allele is almost reached to fixation

Paper:

http://www.plosgenetics.org/article/info%3Adoi%2F10.1371%2Fjournal.pgen.1003912

]]> Rahul Agarwal https://bioinformaticsonline.com/blog/view/40953/explore-taxdump-files Sat, 08 Feb 2020 04:44:55 -0600 https://bioinformaticsonline.com/blog/view/40953/explore-taxdump-files <![CDATA[Explore taxdump files !]]> This is an extract of taxdump-readme.txt to be found at ftp://ftp.ncbi.nih.gov/pub/taxonomy/ The content of the archive -------------------------- It may look like this: delnodes.dmp division.dmp gencode.dmp merged.dmp names.dmp nodes.dmp readme.txt The readme.txt file gives a brief description of *.dmp files. These files contain taxonomic information and are briefly described below. Each of the files store one record in the single line that are delimited by "\t|\n" (tab, vertical bar, and newline) characters. Each record consists of one or more fields delimited by "\t|\t" (tab, vertical bar, and tab) characters. The brief description of field position and meaning for each file follows. nodes.dmp --------- This file represents taxonomy nodes. The description for each node includes the following fields: tax_id -- node id in GenBank taxonomy database parent tax_id -- parent node id in GenBank taxonomy database rank -- rank of this node (superkingdom, kingdom, ...) embl code -- locus-name prefix; not unique division id -- see division.dmp file inherited div flag (1 or 0) -- 1 if node inherits division from parent genetic code id -- see gencode.dmp file inherited GC flag (1 or 0) -- 1 if node inherits genetic code from parent mitochondrial genetic code id -- see gencode.dmp file inherited MGC flag (1 or 0) -- 1 if node inherits mitochondrial gencode from parent GenBank hidden flag (1 or 0) -- 1 if name is suppressed in GenBank entry lineage hidden subtree root flag (1 or 0) -- 1 if this subtree has no sequence data yet comments -- free-text comments and citations names.dmp --------- Taxonomy names file has these fields: tax_id -- the id of node associated with this name name_txt -- name itself unique name -- the unique variant of this name if name not unique name class -- (synonym, common name, ...) division.dmp ------------ Divisions file has these fields: division id -- taxonomy database division id division cde -- GenBank division code (three characters) division name -- e.g. BCT, PLN, VRT, MAM, PRI... comments gencode.dmp ----------- Genetic codes file: genetic code id -- GenBank genetic code id abbreviation -- genetic code name abbreviation name -- genetic code name cde -- translation table for this genetic code starts -- start codons for this genetic code delnodes.dmp ------------ Deleted nodes (nodes that existed but were deleted) file field: tax_id -- deleted node id merged.dmp ---------- Merged nodes file fields: old_tax_id -- id of nodes which has been merged new_tax_id -- id of nodes which is result of merging ]]> Jit https://bioinformaticsonline.com/researchlabs/view/42958/claus-peter-stelzer-lab Mon, 15 Mar 2021 15:24:41 -0500 <![CDATA[Claus-Peter Stelzer Lab]]> Interested in various topics at the intersection of ecology and evolution. In my research I use rotifers as model organisms for experimental studies at the individual and population level. Rotifers are ideally suited for this, because populations of thousands can be kept in small containers in the lab, while single individuals can still be handled conveniently.

More at https://www.uibk.ac.at/limno/personnel/stelzer/index.html.en#research

]]> https://bioinformaticsonline.com/researchlabs/view/5254/mike-ritchie-lab Wed, 02 Oct 2013 15:25:45 -0500 <![CDATA[Mike Ritchie Lab]]> Mike Ritchie Lab primary research focus is the detection of susceptibility genes for common diseases such as cancer, diabetes, hypertension, and cardiovascular disease, among others. The approaches will involve the development and application of new statistical methods with a focus on the detection of gene-gene interactions associated with human disease.

Gene expression and protein expression patterns between normal and non-normal tissues is a growing area of research that may lead to the identification of candidate genes for understanding the etiology of common, complex diseases.

Lab homepage @ http://ritchielab.psu.edu/ritchielab/

]]> https://bioinformaticsonline.com/videolist/watch/10659/gps-dna-tracking-university-of-sheffield Sat, 10 May 2014 04:33:28 -0500 https://bioinformaticsonline.com/videolist/watch/10659/gps-dna-tracking-university-of-sheffield <![CDATA[GPS DNA tracking - University of Sheffield]]> University of Sheffield geneticist and bioinformatics expert Dr Eran Elhaik demonstrates the power of his new DNA research, which allows people to discover their genetic homeland from 1000 years ago. Find out more about our biological research here http://www.sheffield.ac.uk/aps]]> https://bioinformaticsonline.com/researchlabs/view/12989/center-for-molecular-dynamics-nepal-cmdn-nepal Wed, 23 Jul 2014 13:54:51 -0500 <![CDATA[Center for Molecular Dynamics Nepal (CMDN), Nepal]]> Center for Molecular Dynamics Nepal (CMDN), established 2007 prides itself as a research driven nongovernmental organization. Unlike other civil society organizations, CMDN is dedicated entirely to promoting research in the country. With its team of energetic and highly motivated experts, CMDN is now recognized as the leading public health and wildlife research organization of the country.

More at http://www.cmdn.org.np/main/index.php

]]> https://bioinformaticsonline.com/opportunity/view/14899/post-doc-positions-at-the-institute-of-evolution-university-of-haifa-haifa-israel Thu, 04 Sep 2014 03:59:38 -0500 <![CDATA[Post-Doc Positions at the Institute of Evolution, University of Haifa, Haifa, Israel]]> We are looking for independent, motivated, diligent, laborious, dedicated Bioinformaticians as post-doctorate fellows for a project aimed at revealing the mechanisms of cancer-resistance and anti-cancer activity of the hypoxia-tolerant subterranean, blind mole-rat, Spalax along its underground evolutionary adaptations. Our project has captured the interest of the scientific community and we have ample financial support for the studies. Generous fellowships ($30K to $40K according to qualifications and performance) are available, immediately, for Post-Docs experts in bioinformatics with a background of good understanding biological questions. That is that can independently handle raw output data of RNA-seq / miR seq/ Genomic, analyze it and can interpret intelligently the relevant biological background. Outstanding candidates for PhD experienced in Bioinformatics will also be considered. Familiarity with cancer research is an advantage. Experience of writing manuscripts for publication and a publication record in relevant journals are expected. English skills both oral and written are required. American, Western-European or Israeli education is a significant benefit.

Our present objectives is to identify and isolate the substances secreted by Spalax cells, resolve with which components they interact that are active only on cancer cells, in order to unravel the biological mechanisms and pathways that evolved in Spalax cell machinery and ultimately lead to the death of cancer-cells. The study could attest to be a breakthrough in cancer research, using the long lived, hypoxia- and cancer-tolerant Spalax as a significant biological resource for biomedical research that hopefully could open new horizons in treatment and prevention of cancer in humans.

Contact: The applications should be submitted, together with extended CV and bibliography, summary of past accomplishments, and contact information of 3 referees, to Prof of Research Aaron Avivi (aaron@research.haifa.ac.il) AND Dr. Imad Shams (imadshams@gmail.com). (http://bit.ly/1lywShk) aaron@research.haifa.ac.il

More at http://evolution.haifa.ac.il/index.php/29-people/personal-websites/77-personal-site-avivi

]]> https://bioinformaticsonline.com/researchlabs/view/26234/manolis-kellis-lab Sun, 31 Jan 2016 20:51:06 -0600 <![CDATA[Manolis Kellis Lab]]> A major focus of our lab is understanding the effects of genetic variation on molecular phenotypes and human disease. We develop methods for integrating diverse functional genomic datasets of transcription, chromatin modifications, regulator binding, and their changes across multiple conditions to interpret genetic associations, identify causal variants, and predict the effects of genetic perturbations.

More at http://compbio.mit.edu

]]> https://bioinformaticsonline.com/bookmarks/view/27331/andi Fri, 13 May 2016 05:16:35 -0500 https://bioinformaticsonline.com/bookmarks/view/27331/andi <![CDATA[Andi]]> This is the andi program for estimating the evolutionary distance between closely related genomes. These distances can be used to rapidly infer phylogenies for big sets of genomes. Because andi does not compute full alignments, it is so efficient that it scales even up to thousands of bacterial genomes.

This readme covers all necessary instructions for the impatient to get andi up and running. For extensive instructions please consult the manual.

More at https://github.com/evolbioinf/andi/

Address of the bookmark: http://bioinformatics.oxfordjournals.org/content/early/2015/01/13/bioinformatics.btu815.full

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