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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/2882?offset=260</link>
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<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/22402/alessandra-carbone-lab</guid>
  <pubDate>Tue, 26 May 2015 08:54:34 -0500</pubDate>
  <link></link>
  <title><![CDATA[Alessandra Carbone Lab]]></title>
  <description><![CDATA[
<p>Our group works on various problems connected with the functioning and evolution of biological systems. We use mathematical tools, coming from statistics and combinatorics, algorithmic tools and molecular physics tools to study basic principles of cellular functioning starting from genomic data. We run several projects in parallel, all aiming at understanding the basic principles of evolution and co-evolution of molecular structures in the cell. They are intimately linked to each other.</p>

<p>Our main research themes are:</p>

<p>Domain annotation and metagenomics <br />Transcriptomics and sequence analysis<br />Protein evolution and interactions<br />Protein conformational dynamics</p>

<p>More at http://www.lcqb.upmc.fr/AnalGenom/home.html</p>
]]></description>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/22769/ensembl-27</guid>
	<pubDate>Tue, 16 Jun 2015 16:10:36 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/22769/ensembl-27</link>
	<title><![CDATA[Ensembl 27]]></title>
	<description><![CDATA[<h3>What is new?</h3><ul>
<li>Expansion of Protists and Fungi with hundreds of annotated genomes</li>
<li>Variation data for bread wheat, rice, <em>Aedes aegypti</em>, and <em>Ixodes scapularis</em></li>
<li>Whole genome alignments for <em>O. longistaminata</em> and <em>T. cacao</em></li>
<li>Non-coding RNA gene models in <a href="http://bacteria.ensembl.org">Bacteria</a></li>
<li>New assembly of tomato (version 2.50)</li>
<li>Full support for UCSC Track Hub format for hosting your own data in Ensembl</li>
</ul><p>More at http://www.ensembl.info/blog/2015/06/16/ensembl-genomes-release-27-is-out/</p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/25400/arraygen-next-generation-genome-browser-coming-soon</guid>
	<pubDate>Thu, 03 Dec 2015 05:52:09 -0600</pubDate>
	<link>https://bioinformaticsonline.com/news/view/25400/arraygen-next-generation-genome-browser-coming-soon</link>
	<title><![CDATA[ArrayGen Next Generation Genome Browser Coming Soon !!!]]></title>
	<description><![CDATA[<p>The ANG genome browser is a visualization tool, developed by ArrayGen Technologies. This is a fast and an efficient genome browser, built with Javafx and Java swing. ANG genome browser was built for latest next generation sequencing data analysis. It is platform independent and much simpler to use.</p><p>The main features are, it supports many standard file formats such as GFF, BED, GTF, FASTA, VCF, BAM and it can be integrated with other browsers or tools for analysis of genome.</p>]]></description>
	<dc:creator>ArrayGen Technologies</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/26332/pilon</guid>
	<pubDate>Mon, 08 Feb 2016 15:56:18 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/26332/pilon</link>
	<title><![CDATA[Pilon]]></title>
	<description><![CDATA[<p>Pilon is a software tool which can be used to:</p>
<ul>
<li>Automatically improve draft assemblies</li>
<li>Find variation among strains, including large event detection</li>
</ul>
<p>Pilon requires as input a FASTA file of the genome along with one or more BAM files of reads aligned to the input FASTA file. Pilon uses read alignment analysis to identify inconsistencies between the input genome and the evidence in the reads. It then attempts to make improvements to the input genome, including:</p>
<ul>
<li>Single base differences</li>
<li>Small indels</li>
<li>Larger indel or block substitution events</li>
<li>Gap filling</li>
<li>Identification of local misassemblies, including optional opening of new gaps</li>
</ul>
<p>More at https://github.com/broadinstitute/pilon/wiki</p><p>Address of the bookmark: <a href="https://github.com/broadinstitute/pilon/wiki" rel="nofollow">https://github.com/broadinstitute/pilon/wiki</a></p>]]></description>
	<dc:creator>Rahul Nayak</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/30102/prism</guid>
	<pubDate>Sat, 10 Dec 2016 15:19:40 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/30102/prism</link>
	<title><![CDATA[PRISM]]></title>
	<description><![CDATA[<p><span>PRISM is a software for split read (reads which span across a structrual variant -- SV ) mapping and SV calling from the mapping result. PRISM is able to detect small insertions and abitrary size deletions, inversions and tandom duplications with the direction of discordant read pairs. PRISM_CTX is a tool for detecting inter-chromosome trans-location events.&nbsp;</span><br><br><span>PRISM and PRISM_CTX were originally designed and written by&nbsp;</span><a href="http://www.cs.toronto.edu/~brudno">Michael Brudno</a><span>&nbsp;and Yue Jiang, The original PRISM publication can be found&nbsp;</span><a href="http://bioinformatics.oxfordjournals.org/content/early/2012/07/31/bioinformatics.bts484.abstract">here</a><span>.&nbsp;</span><br><br><span>The authors may be contacted via e-mail at:&nbsp;</span><em>prism at cs.toronto.edu</em><span>.&nbsp;</span><br><br><span>Additional information is available in the&nbsp;</span><a href="http://compbio.cs.toronto.edu/prism/PRISM_README">PRISM README</a><span>&nbsp;file and&nbsp;</span><a href="http://compbio.cs.toronto.edu/prism/PRISM_CTX_README">PRISM_CTX README</a><span>&nbsp;file.&nbsp;</span></p>
<p>http://compbio.cs.toronto.edu/prism/</p><p>Address of the bookmark: <a href="http://compbio.cs.toronto.edu/prism/" rel="nofollow">http://compbio.cs.toronto.edu/prism/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/33903/visiting-scientist-computational-genomics</guid>
  <pubDate>Mon, 17 Jul 2017 07:20:18 -0500</pubDate>
  <link></link>
  <title><![CDATA[Visiting Scientist - Computational Genomics]]></title>
  <description><![CDATA[
<p>ICRISAT is a non-profit, non-political organization that conducts agricultural research for development in Asia and sub-Saharan Africa with a wide array of partners throughout the world. ICRISAT and its partners help empower those living in the semi-arid tropics, especially smallholder farmers, to overcome poverty, hunger, malnutrition and a degraded environment through more efficient and profitable agriculture. </p>

<p>ICRISAT is headquartered in Patancheru near Hyderabad, India, with two regional hubs and five country offices in sub-Saharan Africa. ICRISAT, established in 1972, is a member of the CGIAR Consortium. For more details, see www.icrisat.org.</p>

<p>Job Responsibilities:<br />Planning and execution of different NGS/genomics data analysis<br />Apply, maintain, and support cutting-edge pipelines for the analysis and interpretation of NGS data<br />Analyze large-scale genomic datasets generated internally and through collaboration with others<br />Genome wide analysis- LD analysis, hapmap, genetic map construction and qtl mapping<br />Expression analysis based on RNA-seq, gene ontology and metabolic pathway data<br />Sequence level analysis like gene family analysis, orthology/paralogy etc.<br />Familiarity with genomic and biological information databases<br />Compilation and interpretation of results and writing reports<br />Experience working independently and in a team environment<br />Requirements:</p>

<p>PhD or M.Sc with 2-3 years experience from reputed institute in the area of life science or similar Knowledge in Next Generation Sequencing (NGS) data analysis. Should be familiar with various sequencing platforms. Sound knowledge of genomics and molecular biology is must. Proficient in any one of the programming/scripting in languages: Python, Perl, PHP, R, Shell Scripting. Must be experienced in working on Linux and CLI environment. Ability to work as team as well as independently with minimal support. Fluency in spoken and written English is essential. </p>

<p>NGS techniques like sequence alignment, variant calling based on whole genome re-sequencing and genotyping-by-sequencing (GBS), RNA-Seq/transcriptome analysis<br />Knowledge of various standard NGS related tool<br />Ability to solve complex problems in advanced genomics research areas<br />Ease and interest in working with people from diverse backgrounds<br />Excellent oral/written communication and interpersonal/networking skills<br />General: <br />This position is contract for a period of two years.</p>

<p>How to apply:<br />Applicants should apply on or before 27-July-2017, with latest Curriculum Vitae, and the names and contact information of three references that are knowledgeable about your professional qualifications and work experience. All applications will be acknowledged, however only short listed candidates will be contacted<br />Please CLICK HERE to submit your application. <br />ICRISAT is an equal opportunity employer</p>

<p>http://icrisat.careersitemanager.com/job-listings-Visiting-Scientist-Computational-Genomics-ICRISAT-Hyderabad-Secunderabad-2-to-4-years-060717000278</p>
]]></description>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/34929/shendurelab</guid>
  <pubDate>Thu, 28 Dec 2017 09:57:50 -0600</pubDate>
  <link></link>
  <title><![CDATA[ShendureLab]]></title>
  <description><![CDATA[
<p>The mission of our lab is to develop and apply new technologies and methods for genetics, genomics and molecular biology. Most of our work exploits next-generation DNA sequencing which is effectively emerging as a broadly enabling microscope for the measurement of biological phenomena. Our ongoing work generally falls into six areas. These are listed below as links to representative publications in each area.</p>

<p>Developing New Molecular Methods</p>

<p>Genomic Approaches to Developmental Biology</p>

<p>Massively Parallel Functional Genomics</p>

<p>Translating Genomics to the Clinic</p>

<p>Genetic Basis of Human Disease</p>

<p>Genome Sequencing Technologies</p>

<p>http://krishna.gs.washington.edu/index.html<br />http://www.gs.washington.edu/faculty/shendure.htm</p>
]]></description>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/37579/cbs-comparative-microbial-genomics-group-biotools-download-page</guid>
	<pubDate>Wed, 22 Aug 2018 21:59:41 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/37579/cbs-comparative-microbial-genomics-group-biotools-download-page</link>
	<title><![CDATA[CBS Comparative Microbial Genomics group - BioTools download page]]></title>
	<description><![CDATA[<div id="section2">
<p>he CMG-biotools system presents a stand-alone interface for comparative microbial genomics. The package is a customized operating system, based on Xubuntu 10.10, available through the open source Ubuntu project. The system can be installed on a virtual computer, allowing the user to run the system alongside any other operating system. Source codes for all programs are provided under GNU license, which makes it possible to transfer the programs to other systems if so desired. We here demonstrate the package by comparing and analyzing the diversity within the class&nbsp;<em>Negativicutes</em>, represented by 31 genomes including 10 genera. The analyses include 16S rRNA phylogeny, basic DNA and codon statistics, proteome comparisons using BLAST and graphical analyses of DNA structures.</p>
<p>&nbsp;Paper:&nbsp;http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0060120</p>
</div>
<div id="section3"><a name="" title="Conclusion"></a><span></span></div><p>Address of the bookmark: <a href="http://www.cbs.dtu.dk/biotools/CMGtools/" rel="nofollow">http://www.cbs.dtu.dk/biotools/CMGtools/</a></p>]]></description>
	<dc:creator>Neel</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/40955/the-global-alliance-for-genomics-and-health-ga4gh</guid>
	<pubDate>Sat, 08 Feb 2020 07:37:31 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/40955/the-global-alliance-for-genomics-and-health-ga4gh</link>
	<title><![CDATA[The Global Alliance for Genomics and Health (GA4GH)]]></title>
	<description><![CDATA[<p>The Global Alliance for Genomics and Health (GA4GH) is a policy-framing and technical standards-setting organization, seeking to enable responsible genomic data sharing within a <a href="https://www.ga4gh.org/genomic-data-toolkit/regulatory-ethics-toolkit/framework-for-responsible-sharing-of-genomic-and-health-related-data/">human rights framework</a>.</p>
<p>GA4GH core funders and sponsors enable our work and allow us to convene the international genomic data sharing community.</p>
<p>https://www.ga4gh.org/</p><p>Address of the bookmark: <a href="https://www.ga4gh.org/" rel="nofollow">https://www.ga4gh.org/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/42324/comparative-genomics-data-set-including-240-mammals-released</guid>
	<pubDate>Thu, 19 Nov 2020 06:45:39 -0600</pubDate>
	<link>https://bioinformaticsonline.com/news/view/42324/comparative-genomics-data-set-including-240-mammals-released</link>
	<title><![CDATA[Comparative Genomics Data Set Including 240 Mammals Released !]]></title>
	<description><![CDATA[<p>The genome of 130 mammals was sequenced by a large international consortium and the data was analyzed together with 110 existing genomes to allow scientists to identify the important positions in the DNA. This report, published in Nature today will help advance research on human disease mutations and inform how best to protect endangered species.</p><p>In addition to the knowledge of the human genome, all these genomes, widely sampled across mammals, can be used to research how particular organisms respond to different conditions. Some otters, for example, have a thick, water-resistant shell, and some rodents, but not all, have adapted to hibernation. These animal traits will help us to understand human traits, such as metabolic diseases.</p><p><img src="https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41586-020-2876-6/MediaObjects/41586_2020_2876_Fig1_HTML.png?as=webp" alt="image" style="border: 0px; border: 0px;"></p><p>With climate change and more animal ecosystems being threatened by human activity, the protection of endangered species is becoming increasingly important. Scientists have historically researched several people in various populations of a species to understand the genetic variation that occurs in that species. This is important for understanding how particular species can be protected. In this study, animals on the Red List of Endangered Species of the International Union for Conservation of Nature had fewer differences in their genomes, which is consistent with their endangered status.</p><p>Ref @&nbsp;A comparative genomics multitool for scientific discovery and conservation&nbsp;https://www.nature.com/articles/s41586-020-2876-6</p><p>&nbsp;Data at&nbsp;http://zoonomiaproject.org/</p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>

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