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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/28906?offset=1190</link>
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	<description><![CDATA[]]></description>
	
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/41362/genemates-an-r-package-for-detecting-horizontal-gene-co-transfer-between-bacteria-using-gene-gene-associations-controlled-for-population-structure</guid>
	<pubDate>Sat, 07 Mar 2020 05:52:20 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/41362/genemates-an-r-package-for-detecting-horizontal-gene-co-transfer-between-bacteria-using-gene-gene-associations-controlled-for-population-structure</link>
	<title><![CDATA[GeneMates: an R package for Detecting Horizontal Gene Co-transfer between Bacteria Using Gene-gene Associations Controlled for Population Structure]]></title>
	<description><![CDATA[<p><span>GeneMates is an R package implementing a network approach to identify horizontal gene co-transfer (HGcoT) between bacteria using whole-genome sequencing (WGS) data. It is particularly useful for investigating intra-species HGcoT, where presence-absence status of acquired genes is usually confounded by bacterial population structure due to clonal reproduction.</span></p>
<p><a href="https://www.biorxiv.org/content/10.1101/2020.02.29.970970v1">https://www.biorxiv.org/content/10.1101/2020.02.29.970970v1</a></p><p>Address of the bookmark: <a href="https://github.com/wanyuac/GeneMates" rel="nofollow">https://github.com/wanyuac/GeneMates</a></p>]]></description>
	<dc:creator>Rahul Nayak</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/5957/assistant-professor-in-molecular-synthesis-for-drug-discovery-and-development-cbmr-lucknow</guid>
  <pubDate>Wed, 30 Oct 2013 06:42:27 -0500</pubDate>
  <link></link>
  <title><![CDATA[Assistant Professor in Molecular Synthesis for Drug Discovery and Development @ CBMR, Lucknow]]></title>
  <description><![CDATA[
<p>ADVERTISEMENT FOR FACULTY POSITIONS AT CENTRE OF BIOMEDICAL RESEARCH (CBMR), LUCKNOW</p>

<p>Details of the Positions and Pay Structure:</p>

<p>03 Posts for Assistant Professor in Molecular Synthesis for Drug Discovery and Development</p>

<p>Essential Qualifications and Requirements:</p>

<p>1. PhD in Synthetic Organic Chemistry/Medicinal Chemistry with research publications in high quality international journals and first class grade at the preceding degree from recognised University/Institute in India or abroad with consistently good academic record.<br />2. Three Yrs of Post-doctoral experience in relevant area.<br />3. Below 35 Yrs of age at the time of application</p>

<p>Desirable Experience: Candidates having strong research background in organic synthesis, total synthesis of structurally complex and medicinally important natural products/drugs related to cancer, neurodegenerative diseases (neurotropically active molecules for Alzheimer's, Parkinson’s, dementia etc) and infectious diseases such as malaria, TB etc. will be preferred.</p>

<p>Interested candidates may apply with:</p>

<p>1. Filled up Application Form (download from CBMR Website: http://www.cbmr.res.in) along with the Cover Letter, Curriculum Vitae including academic record (Bachelor degree onwards), awards, honours, list of Publications and reprints of 5 best publications.<br />2. Proposed research plan (max 3-4 pages).<br />3. Names and address (with valid e-mail and Phone number) of at least 3 academic referees.<br />4. Online Payment Receipt with transaction reference no. of Rs. 1000/- (USD 100 or equivalent foreign currency) on following details.<br />Account Number: 30054847814 Name: Director, Centre of Biomedical Research<br />Bank: STATE BANK OF INDIA, SGPGI Campus Branch, LUCKNOW</p>

<p>IFSC Code: SBIN0007789<br />MICR No: 22602034</p>

<p>Applications can be sent by registered/speed post or by e-mail to the following address:</p>

<p>The Director,<br />Centre of Biomedical Research (CBMR),<br />Sanjay Gandhi PGI Campus,<br />Raebareli Road, Lucknow-226014<br />e-mail: cbmr.admin@cbmr.res.in,<br />gp.pandey@cbmr.res.in</p>

<p>More Info:</p>

<p>http://www.cbmr.res.in/career/Advertisement%20for%20the%20post%20of%20Professors%20and%20Assistant%20Professors.pdf</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/43698/mimilook-a-phylogenetic-workflow-for-detection-of-gene-acquisition-in-major-orthologous-groups-of-megavirales</guid>
	<pubDate>Mon, 10 Jan 2022 06:32:22 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/43698/mimilook-a-phylogenetic-workflow-for-detection-of-gene-acquisition-in-major-orthologous-groups-of-megavirales</link>
	<title><![CDATA[MimiLook: A Phylogenetic Workflow for Detection of Gene Acquisition in Major Orthologous Groups of Megavirales]]></title>
	<description><![CDATA[<p><span>This tool detects statistically validated events of gene acquisitions with the help of the T-REX algorithm by comparing individual gene tree with NCBI species tree. In between the steps, the workflow decides about handling paralogs, filtering outputs, identifying Megavirale specific OGs, detection of HGTs, along with retrieval of information about those OGs that are monophyletic with organisms from cellular domains of life.&nbsp;</span></p>
<p>https://www.readcube.com/articles/10.3390%2Fv9040072</p><p>Address of the bookmark: <a href="https://pubmed.ncbi.nlm.nih.gov/28387730/" rel="nofollow">https://pubmed.ncbi.nlm.nih.gov/28387730/</a></p>]]></description>
	<dc:creator>Abhi</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/24041/junior-bioinformatic-position</guid>
  <pubDate>Wed, 26 Aug 2015 05:35:28 -0500</pubDate>
  <link></link>
  <title><![CDATA[Junior Bioinformatic position]]></title>
  <description><![CDATA[
<p>Junior Bioinformatic position in the laboratory of Inflammation and immunology in cardiovascular pathologies at Humanitas:</p>

<p>We are seeking a highly motivated young PhD student with strong interest in high throughput data analysis.<br />Detailed descriptions of our recent research activities may be found here:<br />http://www.humanitas-research.org/condorelli-gianluigi-md-phd/</p>

<p>Position is available starting from October/November. A probationary period of one month will be required.<br /> <br />Please send a CV along with a cover letter stating the reasons for applying and contact details of one or more referees to Dr. Paolo Kunderfranco (paolo.kunderfranco@humanitasresearch.it).</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/45299/the-gene-detectives-how-a-new-computational-tool-is-helping-us-read-the-history-written-in-our-genes</guid>
	<pubDate>Thu, 10 Sep 2026 21:23:42 -0500</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/45299/the-gene-detectives-how-a-new-computational-tool-is-helping-us-read-the-history-written-in-our-genes</link>
	<title><![CDATA[The Gene Detectives: How a New Computational Tool Is Helping Us Read the History Written in Our Genes]]></title>
	<description><![CDATA[<p>Imagine opening an ancient family album with no names, dates, or captions. Some photographs are missing, others have been copied, and a few show people who look almost identical. Your challenge is to discover who is related to whom and reconstruct the family story. In evolutionary biology, scientists face a similar mystery when they study genes. Every genome contains clues about its past, but genes can be duplicated, lost, and changed over millions of years, making their history difficult to trace.</p><p>A recent study published in PLOS Computational Biology introduces REvolutionH-tl 2.0 (https://pypi.org/project/revolutionhtl/), a computational tool designed to help solve this mystery. The software analyzes protein sequences and identifies evolutionary relationships between genes. It can help researchers detect important events such as gene duplication, gene loss, and speciation, allowing them to reconstruct how genes evolved across different organisms.</p><p>What makes the tool especially interesting is its focus on both speed and interpretation. The researchers compared REvolutionH-tl 2.0 with several existing computational tools and reported that it achieved competitive accuracy while requiring less computational time in their tests. The tool also includes visualization features, helping researchers turn complicated genetic data into evolutionary stories that are easier to explore.</p><p>Genes are more than simple sequences of DNA; they are records of life&rsquo;s long history. Each surviving gene carries traces of the changes that shaped it. By bringing together computational analysis and visualization, REvolutionH-tl 2.0 acts like a detective, helping scientists uncover these hidden stories. Ultimately, tools like this can improve our understanding of how genomes evolved and how genes acquired the roles they perform today.</p><p>More at&nbsp;https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1013017</p>]]></description>
	<dc:creator>BioStar</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/6268/project-fellow-national-institute-of-malaria-research</guid>
  <pubDate>Tue, 12 Nov 2013 07:40:51 -0600</pubDate>
  <link></link>
  <title><![CDATA[Project Fellow @ National Institute of Malaria Research]]></title>
  <description><![CDATA[
<p>National Institute of Malaria Research</p>

<p>Sector 8, Dwarka, Delhi -110077</p>

<p>WALK IN INTERVIEW</p>

<p>One position of project fellow is to be filled up in a DRL- funded research project on Molecular and morphological characterization of An. fluviatilis in North-eastern states and bordering areas. The position is purely temporary for one year and can be extended</p>

<p>Essential qualifications</p>

<p>Master’s degree in any branch of Life Sciences with hands on experience in molecular biology and/or bioinformatics.</p>

<p>Age limit: 28 years, (relaxation for SC/ST/OBC candidates as per government of India rules)</p>

<p>Stipend: Rs.12, 000.00 per month (fixed)</p>

<p>Eligible candidates may walk in for an interview on 15 November 2013 at 11 AM at the above mentioned address along with a copy of CV (with a passport size photograph affixed), photocopies of all mark sheets/certificates and originals (for verifications). No TA/DA will be paid for attending the interview .Registration of candidates will start at 10:00AM and end at 10:45 AM.</p>

<p>Advertisement: http://www.mrcindia.org/vacancy/add-4.doc</p>
]]></description>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/6560/the-graveley-lab</guid>
  <pubDate>Tue, 19 Nov 2013 18:02:48 -0600</pubDate>
  <link></link>
  <title><![CDATA[The Graveley Lab]]></title>
  <description><![CDATA[
<p>Research in the Graveley lab is primarily focused on the regulation of alternative splicing and small RNA mediated gene regulation. These are fascinating and extraordinarily important mechanisms by which genes can be regulated. Our long-term goals are to understand how these processes are regulated at a mechanistic level and to understand the logic of these processes in significant biological settings. To achieve these goals, we strive to think outside the box to creatively attack the problems being addressed using a wide variety of approaches that include biochemistry, genetics, imaging, deep sequencing, large-scale RNAi screening and bioinformatics.</p>

<p>Lab page @ http://graveleylab.cam.uchc.edu/Graveley/index.html</p>
]]></description>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/7153/phd-student-in-computational-systems-biology</guid>
  <pubDate>Tue, 10 Dec 2013 18:46:05 -0600</pubDate>
  <link></link>
  <title><![CDATA[Ph.D. student in Computational Systems Biology]]></title>
  <description><![CDATA[
<p>Ph.D. student in Computational Systems Biology</p>

<p>Location : The Luxembourg Centre for Systems Biomedicine (LCSB) at the University of Luxembourg, Luxembourg, Luxembourg<br />Deadline for applications : unknown.<br />Description :</p>

<p>The Luxembourg Centre for Systems Biomedicine (LCSB) was created within the Health Technologies Initiative from the Government of Luxembourg as one of the research priorities of the University of Luxembourg. The LCSB is an Interdisciplinary Centre of the University that combines experimental and computational approaches to analyse complex biological systems and disease processes. The Computational Biology Group (CBG) provides the LCSB with a solid infrastructure in developing theoretical framework for computational modeling on biomedical problems, especially in the area of network biology in the context of cellular programming/reprogramming. The CBG group includes researchers with theoretical, computational and wet lab backgrounds, thereby providing an unusually interdisciplinary environment.<br />The Computational Biology Group seeks a highly-skilled Ph.D. student to work on an exciting project on reconstruction and analysis of an integrated gene regulatory network model to elucidate key mechanisms of cellular reprogramming. The model will rely on the integration and mining of diverse transcriptomics and epigenomics data of different cell types from the Central Nervous System. The Ph.D. student is expected to collaborate with other members of the CBG to develop a computational methodology aiming at designing, in-silico, cellular reprogramming events, with a focus on the nervous system. This project will be carried out in collaboration with Prof. Noel Buckleys lab at Kings College London.<br />Requirements of the ideal candidate:<br />Master degree in Bioinformatics, Computer Science, Biology or a related discipline<br />Prior experience in mathematical modelling of biological networks, especially in network inference and analysis<br />Excellent working knowledge in English.<br />.<br />We offer:<br />Full contract for Ph.D. student for three years with possibility of renewal<br />Opportunity to do applied research to medical problems within a highly dynamic research institution (LCSB) and in collaboration with internationally recognized partners<br />An exciting international environment<br />A very competitive salary</p>

<p>For further information, please contact:</p>

<p>Prof. Dr. Antonio del Sol<br />E-mail: antonio.delsol@uni.lu</p>

<p>Applications should contain the following documents:<br />A detailed curriculum vitae<br />cover letter mentioning the reference number<br />description of past research experience and future interests<br />name and addresses of three referees</p>

<p>All applications should be sent preferably in electronic version until December 31st, 2013 to the following address:</p>

<p>Luxembourg Centre for Systems Biomedicine (LCSB)<br />University of Luxembourg<br />7, avenue des Hauts-Fourneaux<br />L-4362 Esch-sur-Alzette<br />Tel: +352-466644-6982 (Office)<br />Email: antonio.delsol@uni.lu<br />http://www.lcsb.lu</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/38752/hgtector-an-automated-method-facilitating-genome-wide-discovery-of-putative-horizontal-gene-transfers</guid>
	<pubDate>Mon, 21 Jan 2019 06:50:05 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/38752/hgtector-an-automated-method-facilitating-genome-wide-discovery-of-putative-horizontal-gene-transfers</link>
	<title><![CDATA[HGTector: an automated method facilitating genome-wide discovery of putative horizontal gene transfers]]></title>
	<description><![CDATA[<p>A computational pipeline for genome-wide detection of putative horizontal gene transfer (HGT) events based on sequence homology search hit distribution statistics</p>
<p>Authors: Qiyun Zhu (<a href="mailto:qiyunzhu@gmail.com">qiyunzhu@gmail.com</a>), Katharina Dittmar (<a href="mailto:katharinad@gmail.com">katharinad@gmail.com</a>)</p>
<p>Affiliation: Department of Biological Sciences, University at Buffalo, State University of New York, Buffalo, USA</p>
<p>Zhu Q, Kosoy M, Dittmar K. HGTector: an automated method facilitating genome-wide discovery of putative horizontal gene transfers.&nbsp;<em style="font-size: 12.8px;">BMC Genomics</em>. 2014. 15:717.</p>
<p>Usage: Simply execute&nbsp;<span style="font-size: 12.8px;">perl HGTector.pl</span>, or, open&nbsp;<span style="font-size: 12.8px;">GUI.html</span>&nbsp;in a web browser to see a step-by-step wizard.</p>
<p>Download&nbsp;<a href="https://github.com/DittmarLab/HGTector/archive/0.2.2.zip">HGTector 0.2.2</a>.</p><p>Address of the bookmark: <a href="https://github.com/DittmarLab/HGTector" rel="nofollow">https://github.com/DittmarLab/HGTector</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/6836/research-fellow-mendel-laboratory</guid>
  <pubDate>Tue, 26 Nov 2013 00:07:57 -0600</pubDate>
  <link></link>
  <title><![CDATA[Research Fellow @ Mendel laboratory]]></title>
  <description><![CDATA[
<p>IRCCS Casa Sollievo della Sofferenza – Mendel laboratory is seeking one talented bioinformatician (Rome)<br />Start date: immediate</p>

<p>Duration: 1 year</p>

<p>Funding Source: Institutional<br />Salary on grant: B2 (€ 22.000/year gross)<br />Contact Person (Referent): Tommaso Mazza<br />Ref. E-Mail: t.mazza@css-mendel.it<br />Tel: +39 06 44160526<br />Fax: +39 06 44160548</p>

<p>Job Description: The bioinformatics unit at IRCCS Casa Sollievo della Sofferenza - Mendel laboratory in Rome is looking for one young PhD bioinformatician with specific experience and/or interest in the analysis of transcriptomic data.</p>

<p>The candidate will be mainly in charge of developing research on a range of hot applications and projects, dealing with microarrays, RNA-Seq and miRNA-Seq data. Main activities will be: (i) data analysis (short-reads mapping, variants call and annotation, functional enrichment analysis of gene expression data); (ii) networks analysis and simulation (artificial knockout, redundancy and lethality analysis, gene set essentiality); (iii) developing of ad-hoc software solutions/routines on clusters of CPUs and GPUs.</p>

<p>The correct cultural background (training in Biology / Computer Science / Statistics or a mix of the three) and a strong interest in working with high throughput data analysis will be considered at the same level of specific experience in the above-mentioned fields.<br />Knowledge of molecular modeling and simulation and one of these languages: python, perl, R, Java, C++, C# is a golden plus. Good knowledge of Scientific English will be positively evaluated for this position, together with good presentation and teamwork skills.</p>

<p>A CV with one professional reference, details on educational background and of the biological and/or bioinformatic and/or data analysis skills and experience should be sent by email for a preliminary selection to: Tommaso Mazza, CSS-Mendel: t.mazza@css-mendel.it</p>

<p>Context<br />Casa Sollievo della Sofferenza is an Institute for hospitalization, care, and scientific research located in San Giovanni Rotondo, Italy. It integrates clinical assistance (with inpatient and outpatient facilities) and research. It has an affiliate institute, CSS-Mendel, located in Rome. Between the two sites, it employs over 100 researchers who focus on genetics. The Center is equipped with state of the art genomics technology (SOLiD 5500XL next generation sequencer, Illumina MiSeq, Affymetrix/Agilent microarray platforms, etc) as well as a dedicated high performance computing facility, a non-conventional workstation of GPUs and a short- and long-term storage disk.</p>

<p>Applications<br />Candidates should send:<br />• a cover letter explaining the role they would like to undertake within the Center, even if it is not listed in this job adv, stating clearly why they would be a good fit to the proposed role, and what they would bring to the Center in terms of expertise, ideas, talent;<br />• a CV including a list of publications;<br />• List of referees;</p>

<p>More at http://www.css-mendel.it/</p>
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