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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/29274?offset=1170</link>
	<atom:link href="https://bioinformaticsonline.com/related/29274?offset=1170" rel="self" type="application/rss+xml" />
	<description><![CDATA[]]></description>
	
	
<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/21930/bioinformatics-ra-at-ivri</guid>
  <pubDate>Tue, 07 Apr 2015 03:10:53 -0500</pubDate>
  <link></link>
  <title><![CDATA[Bioinformatics RA at IVRI]]></title>
  <description><![CDATA[
<p>A walk in interview is scheduled in the seminar hall of Veterinary Biotechnology Division of the institute on 9.04.15 at 10.30 am for the engagement of one Research associate (RA) in ICAR funded time bound project entitled “Centre for Agricultural bioinformatics (CABin)”.</p>

<p>The engagement is purely temporary on contractual basis and co-terminus with the project. There will be no provision of absorption of absorption/reemployment in IVRI/DBT on termination of the project.</p>

<p>No TA/DA will be provided for appearing in the interview and no separate letter will be issued.</p>

<p>A. Name tile of the project: “Centre for Agricultural bioinformatics (CABin)”.</p>

<p>B. Position/post to be filled: Research Associate (one)</p>

<p>C. Essential/Desirable qualifications:</p>

<p>•Essential: M.V.Sc./M.Tech./MSc Degree in Biotechnology/ Biochemistry/ Microbiology/Immunology/Bioinformatics/Genetics/Life Sciences or</p>

<p>Masters in Computer Application/ Masters in Computer science with first division.</p>

<p>• Desirable: Experience in cell culture, next generation sequencing, C++ and perl programming. NET/GATE qualified will be preferred.</p>

<p>• Experience : At least 2 years</p>

<p>D. Emoluments: Rs. 23000/- per month + 20% HRA</p>

<p>E. Age Limit: Maximum 40 years for men and 45 years for women</p>

<p>F. Duration of the project: Up to March 2017</p>

<p>G. Name of PI/Contact person: Dr. G.V.P.P.S. Ravi Kumar, Sr. Scientist, Division of Veterinary Biotechnology.</p>

<p>H. Address for correspondence: Dr. G.V.P.P.S. Ravi Kumar, Sr. Scientist, Computational Biology and Genomics facility,Division of Veterinary Biotechnology, I.V.R.I., Izatnagar – 243122</p>

<p>Advertisement: www.ivri.nic.in/jobs/WalkIn_interview_01042015.pdf</p>
]]></description>
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<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/43799/kast</guid>
	<pubDate>Wed, 23 Feb 2022 08:28:36 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/43799/kast</link>
	<title><![CDATA[KAST]]></title>
	<description><![CDATA[<p><span>Perform Alignment-free k-tuple frequency comparisons from sequences. This can be in the form of two input files (e.g. a reference and a query) or a single file for pairwise comparisons to be made.</span></p><p>Address of the bookmark: <a href="https://github.com/martinjvickers/KAST" rel="nofollow">https://github.com/martinjvickers/KAST</a></p>]]></description>
	<dc:creator>Neel</dc:creator>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/22066/jrf-bioinformatics-national-institute-of-immunology-new-delhi-110067</guid>
  <pubDate>Fri, 17 Apr 2015 02:39:37 -0500</pubDate>
  <link></link>
  <title><![CDATA[JRF Bioinformatics @ NATIONAL INSTITUTE OF IMMUNOLOGY  NEW DELHI-110067]]></title>
  <description><![CDATA[
<p>Applications are invited for the position of Junior Research Fellow (Project)/Senior Research Fellow (Project) for the following time-bound sponsored project as per the details given below:</p>

<p>1. “Development of bioinformatics methods for identifying novel secondary metabolites by genome mining” funded by DBT</p>

<p>JRF (P)/SRF (P) (One Position only)</p>

<p>Dr. Debasisa Mohanty Staff Scientist-VI deb@nii.res.in</p>

<p>Educational Qualifications: JRF (Project): M.Sc (Bioinformatics/ Biophysics/Biotechnology or any other stream of biological/physical sciences) or M.Tech. (Bioinformatics/Biotechnology/Computational Sciences) of M. Pharm.</p>

<p>SRF (Project): M.Sc (Bioinformatics/Biophysics/Biotechnology or any other stream of biological/physical sciences) or M.Tech. (Bioinformatics/Biotechnology/Computational Sciences) of M. Pharm with atleast 03 years of research experience.</p>

<p>Desirable Qualifications: Strong computer programming skills (in PERL/CGI/PHP or C++ or object oriented database management systems like MySQL etc or scripting languages under LINUX/UNIX environment) and sufficient experience in computational analysis of biological/biochemical data.</p>

<p>The candidates must highlight their experience in programming and database development in their CV. Job description: Computational analysis of genomes and development of bioinformatics tools and software’s for sequence and structure based analysis of biosynthetic pathways.</p>

<p>Emoluments: The selected candidates will draw consolidated emoluments as per Institute Rules, depending upon qualifications &amp; experience JRF (Project): Rs. 12,000/- per month plus 30% HRA SRF (Project): Rs. 14,000/- per month plus 30% HRA (*Candidates possessing qualifications as per latest DST OM, will be given revised scales). </p>

<p>More at http://www1.nii.res.in/sites/default/files/projectappointments-Dr.DebasisaMohanty-30April2015.pdf</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/44223/ale-assembly-likelihood-estimator</guid>
	<pubDate>Wed, 08 Mar 2023 01:39:33 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/44223/ale-assembly-likelihood-estimator</link>
	<title><![CDATA[ALE: Assembly Likelihood Estimator]]></title>
	<description><![CDATA[<p>Just import the assembly, bam and ALE scores. You can convert the .ale file to a set of .wig files with ale2wiggle.py and IGV can read those directly.&nbsp; Depending on your genome size you may want to convert the .wig files to the BigWig format.</p><p>Address of the bookmark: <a href="https://github.com/sc932/ALE" rel="nofollow">https://github.com/sc932/ALE</a></p>]]></description>
	<dc:creator>BioStar</dc:creator>
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<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/22026/igib-recruitment-2015-%E2%80%93-project-scientist</guid>
  <pubDate>Tue, 14 Apr 2015 12:19:59 -0500</pubDate>
  <link></link>
  <title><![CDATA[IGIB Recruitment 2015 – Project Scientist]]></title>
  <description><![CDATA[
<p>IGIB Recruitment 2015 – Project Scientist &amp; SPF Posts: CSIR – Institute of Genomics &amp; Integrative Biology (IGIB) has issued notification for the recruitment of Project Scientist, Sr Project Fellow vacancies on temporary basis for project entitled “Setting up of CSIR(unit)-TRISUTRA (Translational research and Innovative Science through Ayurgenomics)”. Eligible candidates may apply in prescribed application format on or before 23-04-2015. Other details like age limit, educational qualification, selection process &amp; how to apply are given below…</p>

<p>IGIB Vacancy Details:<br />Total No. of Posts: 04<br />Name of the Posts:<br />1. Project Scientist (Biology): 02 Posts<br />2. Project Scientist (Bioinformatics): 01 Post<br />3. Sr Project Fellow (Ayurveda): 01 Post</p>

<p>Age Limit: Candidates age should be 35 years for post 1, 32 years for post 2</p>

<p>Educational Qualification: Candidates should have Ph.D/ Ph.D submitted in any branch of Biological Science/ Life Science for post 1, Ph.D/ Ph.D submitted in Bioinformatics for post 2, BAMS degree with one year internship for post 3.</p>

<p>Selection Process: Candidates will be selected based on their performance in interview.</p>

<p>How to Apply: Eligible candidates may send their application along with all relevant documents on or before 23-04-2015.</p>

<p>Important Dates:<br />Last Date for Receipt of Application for Post 1 &amp; 2: 23-04-2015.<br />Date of Interview for Post 3: 27-04-2015.</p>

<p>For other details like pay scale, age relaxation, educational qualification, selection process, how to apply, etc., click on the link given below…</p>

<p>http://www.freejobalert.com/wp-content/uploads/2015/03/Notification-IGIB-Project-Scientist-SPF-Posts.pdf</p>

<p>http://www.igib.res.in/sites/default/files/27042015.pdf</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/pages/view/44371/steps-to-find-all-the-repeats-in-the-genome</guid>
	<pubDate>Thu, 31 Aug 2023 02:43:28 -0500</pubDate>
	<link>https://bioinformaticsonline.com/pages/view/44371/steps-to-find-all-the-repeats-in-the-genome</link>
	<title><![CDATA[Steps to find all the repeats in the genome !]]></title>
	<description><![CDATA[<div><p>To find repeats in a genome from 2 to 9 length using a Perl script, you can use the RepeatMasker tool with the "--length" option<a href="https://mobilednajournal.biomedcentral.com/articles/10.1186/1759-8753-5-13" target="_blank">[0]</a>. Here's a step-by-step guide:</p></div><div><ol>
<li>Install RepeatMasker: First, you need to install RepeatMasker on your system. You can download it from the RepeatMasker website<a href="https://mobilednajournal.biomedcentral.com/articles/10.1186/1759-8753-5-13" target="_blank">[0]</a>.</li>
</ol></div><div><ol>
<li>Prepare the genome sequence: Make sure you have the genome sequence in a FASTA file format. Let's assume the file is named "genome.fasta".</li>
</ol><blockquote><p>./RepeatMasker -pa &lt;number_of_processors&gt; -nolow -norna -no_is -div &lt;divergence_value&gt; -lib RepeatMaskerLib.embl -gff -xsmall -small -poly -species &lt;species_name&gt; -dir &lt;output_directory&gt; -length &lt;min_length&gt;-&lt;max_length&gt; genome.fasta</p></blockquote><div><p>Replace the following placeholders with appropriate values:</p><ul>
<li><code>&lt;number_of_processors&gt;</code>: The number of processors/threads you want to use for parallel processing.</li>
<li><code>&lt;divergence_value&gt;</code>: The divergence value for the species you are analyzing. You can find divergence values for different species in the RepeatMasker documentation<a href="https://mobilednajournal.biomedcentral.com/articles/10.1186/1759-8753-5-13" target="_blank">[0]</a>.</li>
<li><code>&lt;species_name&gt;</code>: The name of the species you are analyzing.</li>
<li><code>&lt;output_directory&gt;</code>: The directory where you want the output files to be saved.</li>
<li><code>&lt;min_length&gt;</code>&nbsp;and&nbsp;<code>&lt;max_length&gt;</code>: The minimum and maximum lengths of the repeats you want to find (in this case, 2 and 9).</li>
</ul></div><div><ol>
<li>Analyze the output: RepeatMasker will generate several output files, including a .out file. You can parse this file to extract the information you need. There is a Perl tool called "one_code_to_find_them_all.pl" that can help you parse RepeatMasker output files<a href="https://mobilednajournal.biomedcentral.com/articles/10.1186/1759-8753-5-13" target="_blank">[0]</a>. You can download it from the source provided.</li>
</ol></div><div><ol>
<li>Use the provided Perl script: Once you have the "one_code_to_find_them_all.pl" script, you can run it to conveniently parse the RepeatMasker output files. Here's an example of how to use it:</li>
</ol><blockquote><p>perl one_code_to_find_them_all.pl --rm &lt;RepeatMasker_out_file&gt; --length &lt;length_file&gt;</p></blockquote></div><p>&nbsp;</p></div><div><div><p>Replace&nbsp;<code>&lt;RepeatMasker_out_file&gt;</code>&nbsp;with the path to your RepeatMasker .out file, and&nbsp;<code>&lt;length_file&gt;</code>&nbsp;with the path to a file containing the lengths of the reference elements.</p></div><div><p>This script will generate several output files, including .log.txt and .copynumber.csv, which contain quantitative information about the identified repeat elements.</p></div><div><p>Remember to adjust the parameters and options according to your specific needs and the characteristics of your genome.</p></div></div>]]></description>
	<dc:creator>Neel</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/file/view/22047/binc-sample-question-paper</guid>
	<pubDate>Thu, 16 Apr 2015 09:14:14 -0500</pubDate>
	<link>https://bioinformaticsonline.com/file/view/22047/binc-sample-question-paper</link>
	<title><![CDATA[BINC Sample Question Paper !!!]]></title>
	<description><![CDATA[<p>BINC sample question paper round TWO.</p>]]></description>
	<dc:creator>Jitendra Narayan</dc:creator>
	<enclosure url="https://bioinformaticsonline.com/file/download/22047" length="1621" type="text/plain" />
</item>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/pages/view/44637/tools-to-access-the-quality-of-your-assembled-genome</guid>
	<pubDate>Thu, 08 Aug 2024 23:31:18 -0500</pubDate>
	<link>https://bioinformaticsonline.com/pages/view/44637/tools-to-access-the-quality-of-your-assembled-genome</link>
	<title><![CDATA[Tools to access the quality of your assembled genome !]]></title>
	<description><![CDATA[<ul dir="auto">
<li><a href="https://github.com/linsalrob/fasta_validator">FASTA VALIDATOR</a>&nbsp;+&nbsp;<a href="https://github.com/shenwei356/seqkit">SEQKIT RMDUP</a>: FASTA validation</li>
<li><a href="https://genometools.org/tools/gt_gff3validator.html">GENOMETOOLS GT GFF3VALIDATOR</a>: GFF3 validation</li>
<li><a href="https://github.com/PlantandFoodResearch/assemblathon2-analysis/blob/a93cba25d847434f7eadc04e63b58c567c46a56d/assemblathon_stats.pl">ASSEMBLATHON STATS</a>: Assembly statistics</li>
<li><a href="https://genometools.org/tools/gt_stat.html">GENOMETOOLS GT STAT</a>: Annotation statistics</li>
<li><a href="https://github.com/ncbi/fcs">NCBI FCS ADAPTOR</a>: Adaptor contamination pass/fail</li>
<li><a href="https://github.com/ncbi/fcs">NCBI FCS GX</a>: Foreign organism contamination pass/fail</li>
<li><a href="https://gitlab.com/ezlab/busco">BUSCO</a>: Gene-space completeness estimation</li>
<li><a href="https://github.com/tolkit/telomeric-identifier">TIDK</a>: Telomere repeat identification</li>
<li><a href="https://github.com/oushujun/LTR_retriever/blob/master/LAI">LAI</a>: Continuity of repetitive sequences</li>
<li><a href="https://github.com/DerrickWood/kraken2">KRAKEN2</a>: Taxonomy classification</li>
<li><a href="https://github.com/igvteam/juicebox.js">HIC CONTACT MAP</a>: Alignment and visualisation of HiC data</li>
<li><a href="https://github.com/mummer4/mummer">MUMMER</a>&nbsp;&rarr;&nbsp;<a href="http://circos.ca/documentation/">CIRCOS</a>&nbsp;+&nbsp;<a href="https://plotly.com/">DOTPLOT</a>&nbsp;&amp;&nbsp;<a href="https://github.com/lh3/minimap2">MINIMAP2</a>&nbsp;&rarr;&nbsp;<a href="https://github.com/schneebergerlab/plotsr">PLOTSR</a>: Synteny analysis</li>
<li><a href="https://github.com/marbl/merqury">MERQURY</a>: K-mer completeness, consensus quality and phasing assessment</li>
</ul>]]></description>
	<dc:creator>LEGE</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/22072/bioinformatics-jrfrasrf-position-at-indian-institute-of-science-education-and-research-iiser-kolkata-kolkata-west-bengal</guid>
  <pubDate>Fri, 17 Apr 2015 04:11:14 -0500</pubDate>
  <link></link>
  <title><![CDATA[Bioinformatics JRF/RA/SRF position at Indian Institute of Science Education and Research (IISER Kolkata) - Kolkata, West Bengal]]></title>
  <description><![CDATA[
<p>Research Position in Computational Biology in the group of Shree P. Pandey Positions available in the area of NGS data analysis, bioinformatics, plant genomics</p>

<p>Project Description: Projects involves high throughput analysis of data mostly generated by massively parallel sequencing (RNA-Seq and small-RNA-Seq), microarrays and related platforms. We are looking for highly motivated and bright individuals interested in high-throughput cutting-edge data analyses methods in genomics (computational positions). Available positions: Applications are invited from suitable candidates in both, the Max Planck India Partner Program and the CRP Wheat Program for openings at the levels:</p>

<p>Post Name-Qualification-Salary:<br />Project assistant – Master’s – Rs. 14000<br />Project fellow (junior data analyst) – Masters + research experience – Rs. 16000<br />Research fellow (senior data analyst) – Masters + adequate research experience/desirable skill sets – Rs. 22000<br />Research Associated – PhD (&lt; 1yr) /&gt; 1 yr experience – Rs. 28000 / Rs. 32000<br />Essential qualification: MSc/MTech/PhD (or other suitable qualification) in discipline related to bioinformatics, computational biology, computer application (or equivalent)/ ‘Advance Post-Graduate Diploma in Bioinformatics’. Proficiency in one of the programming languages or statistics (proficient in R for example) is compulsory.<br />Desirable qualification: 1. Programming experiences in at least one low level language such as C/C++ and one scripting language such as Perl/Python/PHP and knowledge of SQL/MySQL. 2. Substantial experience in the linux or other unix environments. 3. Experience of working in projects on Bioinformatics, Genetics or Biological application areas/Computational and Statistical analysis (e.g. using R or Matlab). Experience in the field of genomics (NGS, microarrays, genome annotation), database development and management, software development, systems and network biology (or related fields) will be preferred.<br />SELECTION PROCEDURE FOR INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH (IISER KOLKATA) – RESEARCH ASSOCIATE &amp; MORE VACANCIES POST:</p>

<p>Candidates can apply on or before 30/04/2015<br />No Detailed information about the selection process is mentioned in the recruitment notification<br />HOW TO APPLY FOR RESEARCH ASSOCIATE &amp; MORE VACANCIES IN INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH (IISER KOLKATA):</p>

<p>Applications should contain CV along with brief description (maximum 1 page) of research conducted (highlighting skills and experience) till now. Applications should be sent by email to Shree P. Pandey, Department of Biological Sciences, IISER-Kolkata, Mohanpur Campus, West Bengal within 2 weeks. Interviews will be scheduled within 10 days of closing of applications. E-mail: sppiiserkol@gmail.com, sppandey@iiserkol.ac.in<br />For more details visit: http://www.iiserkol.ac.in/~sppandey</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/44766/genome-simulation-with-slim-and-msprime</guid>
	<pubDate>Fri, 31 Jan 2025 12:47:43 -0600</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/44766/genome-simulation-with-slim-and-msprime</link>
	<title><![CDATA[Genome Simulation with SLiM and msprime]]></title>
	<description><![CDATA[<p>Genome simulation is an essential tool in population genetics, enabling researchers to model evolutionary processes and study genetic variation. Two widely used simulation tools in this field are <strong style="font-size: 12.8px;">SLiM</strong><span style="font-size: 12.8px; font-weight: normal;"> and </span><strong style="font-size: 12.8px;">msprime</strong><span style="font-size: 12.8px; font-weight: normal;">. While both serve different purposes, they can be used together with the </span><strong style="font-size: 12.8px;">slendr</strong><span style="font-size: 12.8px; font-weight: normal;"> framework to compare simulation outputs effectively.</span></p><h2>Overview of SLiM and msprime</h2><h3>SLiM: Forward Genetic Simulator</h3><p>SLiM is a <strong>free, open-source</strong> tool designed for forward genetic simulations. It allows researchers to model complex evolutionary scenarios, including selection, recombination, and demographic events, making it particularly useful for studying adaptation and selection in populations.</p><p><strong>Key Features of SLiM:</strong></p><ul>
<li>
<p>Simulates population evolution forward in time</p>
</li>
<li>
<p>Supports custom evolutionary models using an embedded scripting language</p>
</li>
<li>
<p>Allows modeling of spatial and ecological dynamics</p>
</li>
<li>
<p>Provides high flexibility and extensibility for user-defined scenarios</p>
</li>
<li>
<p>Available on GitHub as an open-source project</p>
</li>
</ul><h3>msprime: Ancestry and Mutation Simulator</h3><p>msprime is an efficient, <strong>open-source</strong> tool that simulates ancestry and mutations using a coalescent framework. It is known for its high-speed performance and low memory requirements, making it a popular choice for large-scale genomic simulations.</p><p><strong>Key Features of msprime:</strong></p><ul>
<li>
<p>Implements coalescent simulations for ancestry modeling</p>
</li>
<li>
<p>Efficiently simulates large population histories</p>
</li>
<li>
<p>Supports the addition of mutations to genealogies</p>
</li>
<li>
<p>Developed using an open-source community model</p>
</li>
<li>
<p>Often faster and more memory-efficient than alternative simulators</p>
</li>
</ul><h2>Using SLiM and msprime with slendr</h2><p>Both SLiM and msprime can be integrated with <strong>slendr</strong>, a framework that facilitates structured population genetic simulations. This integration allows for seamless comparison of simulation outputs.</p><h3>How They Work Together:</h3><ul>
<li>
<p>SLiM and msprime simulations can be analyzed within slendr.</p>
</li>
<li>
<p>The <strong>ts_read()</strong> function in slendr enables loading and comparing tree sequence outputs from both simulators.</p>
</li>
<li>
<p>This integration allows researchers to validate simulation results and gain deeper insights into evolutionary processes.</p>
</li>
</ul><h2>Performance Considerations</h2><p>While SLiM offers powerful forward simulations with extensive customization, msprime is often preferred for its <strong>speed and memory efficiency</strong> when simulating ancestry and mutations. The choice between the two depends on the research goals:</p><ul>
<li>
<p><strong>For detailed evolutionary modeling with selection and recombination:</strong> Use SLiM.</p>
</li>
<li>
<p><strong>For large-scale coalescent simulations with mutations:</strong> Use msprime.</p>
</li>
<li>
<p><strong>For comparing different simulation models and their outputs:</strong> Use slendr to integrate SLiM and msprime results.</p>
</li>
</ul><h2>Conclusion</h2><p>SLiM and msprime are valuable tools for genome simulation, each serving distinct but complementary purposes in population genetics research. By leveraging the strengths of both simulators with slendr, researchers can conduct robust and efficient evolutionary simulations, enhancing our understanding of genetic diversity and adaptation.</p><p>For more information, check out the official GitHub repositories for <strong>SLiM</strong> and <strong>msprime</strong>, and explore the <strong>slendr</strong> framework for streamlined simulation workflow</p>]]></description>
	<dc:creator>BioStar</dc:creator>
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