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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/29280?offset=840</link>
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	<description><![CDATA[]]></description>
	
	
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/22429/walk-ins-for-jrf-ans-srf-post-in-nirrh-mumbai</guid>
  <pubDate>Thu, 28 May 2015 19:04:57 -0500</pubDate>
  <link></link>
  <title><![CDATA[Walk-ins for JRF ans SRF post in NIRRH, Mumbai]]></title>
  <description><![CDATA[
<p>Title of project- "EXPLORING THE HINGE AND TRANSMEMBRANE REGION OF HUMAN FSHR FOR DESIGN OF SMALL MOLECULE AND PEPTIDOMIMETIC MODULATORS"<br />Name of the Post- Junior Research Fellow<br />No. of vacancy- One<br />Stipend- Rs. 25000/ +30% HRA<br />Essential qualification- Candidate should be Post Graduate Degree in Life Sciences / Bioinformatics /Pharmacology/ Chemistry or any other relevant area of Biology or Graduate Degree in Professional Course with NET qualification or Post Graduate Degree in Professional Course.<br />Desirable- Candidate with Good knowledge of protein structures, docking, MD simulations will be preferred.<br />Age Limit- Not exceeding 28 Years<br />Duration of project- Upto May 2018</p>

<p>Title of project- "Analysis of the structures of known antimicrobial peptides using machine learning algorithms and molecular dynamics simulations".<br />Name of the Post- Senior Research Fellow<br />No. of vacancy- One<br />Stipend- Rs. 14000/ +30% HRA<br />Essential qualification- Candidate should be having M.Sc. degree in Life Sciences / Bioinformatics / Pharmacology/ Chemistry or any other relevant area of Biology and 2 years of research experience.<br />Desirable- Candidate with Good knowledge of protein structures, docking, MD simulations will be preferred.<br />Age Limit- Not exceeding 35 Years<br />Duration of project- Upto April 2016<br />How to Apply- Interested candidates can download the application form from below mentioned link- http://www.nirrh.res.in/links/BiodataForm.pdf<br />Candidate must bring the filled up application form along with all the relevant documents in original and one set of attested photocopies of the same and one passport size recent colour photograph.</p>

<p>Ref. - http://www.nirrh.res.in/links/job_jrf-srf.htm</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/44168/environmental-genomics-group-scilifelabkth-stockholm</guid>
	<pubDate>Thu, 01 Dec 2022 01:12:43 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/44168/environmental-genomics-group-scilifelabkth-stockholm</link>
	<title><![CDATA[Environmental Genomics Group SciLifeLab/KTH Stockholm]]></title>
	<description><![CDATA[<p>Useful Metagenomics resources</p><p>Address of the bookmark: <a href="https://github.com/envgen" rel="nofollow">https://github.com/envgen</a></p>]]></description>
	<dc:creator>BioStar</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/22286/jrf-bioinformatics-pune-university</guid>
  <pubDate>Wed, 06 May 2015 06:21:09 -0500</pubDate>
  <link></link>
  <title><![CDATA[JRF Bioinformatics @ Pune University]]></title>
  <description><![CDATA[
<p>Pune University is inviting applications from indian citizens for recruiting following posts:</p>

<p>Vacancies:<br />Junior Research Fellow-04<br />Age Limits:<br />Candidates age should be not more than 28 years.<br />Qualification:<br />Candidates should possess M.Sc in Microbiology/ Marine microbiology/Marine Biotechnology/ Bioinformatics/Zoology or equivalent degree with minimum 60% marks.<br />Selection Process:<br />Shortlisted candidates will be called for interview.<br />How to Apply:<br />Eligible candidates may send their applications in the prescribed format along with CV in an envelope should be superscribed as the "Application for the post of JRF" to Head Department of Zoology, Savitribai Phule Pune University on or before 10-05-2015.<br />Last Date:<br />10-05-2015</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/44342/ncbi-datasets%E2%80%AFpages</guid>
	<pubDate>Wed, 12 Jul 2023 06:29:31 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/44342/ncbi-datasets%E2%80%AFpages</link>
	<title><![CDATA[NCBI Datasets pages]]></title>
	<description><![CDATA[<p>Update! Assembly and Genome record pages now redirect to new NCBI Datasets pages. NCBI Datasets is a new resource that makes it easier to find and download genome data. Learn more: https://ncbiinsights.ncbi.nlm.nih.gov/2023/07/11/ncbi-datasets-genome-assembly-pages/&nbsp;<a href="https://ow.ly/GU3o50P8QH4"></a><a href="https://www.linkedin.com/feed/hashtag/?keywords=ncbicgr&amp;highlightedUpdateUrns=urn%3Ali%3Aactivity%3A7084592728260386816">#NCBICGR</a></p><p><span>Effective July 10, 2023, NCBI&rsquo;s Assembly and Genome record pages now redirect to&nbsp;</span>new<a href="https://www.ncbi.nlm.nih.gov/datasets/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=datasets-genome-assembly-redirect-20230711"> NCBI Datasets </a><span>pages. As&nbsp;</span><a href="https://ncbiinsights.ncbi.nlm.nih.gov/2023/03/07/ncbi-datasets-genome-taxonomy-pages/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=datasets-genome-assembly-redirect-20230711">previously announced</a><span>, these updates are part of our ongoing effort to modernize and improve your user experience. NCBI Datasets is a new resource that makes it easier to find and download genome data.  </span><span>&nbsp;</span></p><h5>The following pages have been updated:</h5><ul>
<li><span>The NCBI Assembly record pages now redirect to the new </span><a href="https://www.ncbi.nlm.nih.gov/datasets/genome/GCF_023065955.2/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=datasets-genome-assembly-redirect-20230711"><span>NCBI Datasets</span><strong><span> </span></strong><span>Genome</span></a><span> </span><span>record pages that describe assembled genomes and provide links to related NCBI tools such as Genome Data Viewer and BLAST. </span><span>&nbsp;</span></li>
<li><span>The NCBI</span><strong> </strong><span>Genome record pages now redirect to the </span><a href="https://www.ncbi.nlm.nih.gov/datasets/taxonomy/9644/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=datasets-genome-assembly-redirect-20230711"><span>NCBI Datasets</span><strong><span> </span></strong><span>Taxonomy</span></a><span> </span><span>record pages that provide a taxonomy-focused portal to genes, genomes, and additional NCBI resources.  </span><span>&nbsp;</span></li>
</ul><p><span>During this transition, you will have the option to return to the legacy Genome and Assembly record pages. We will remove the legacy pages in early 2024. </span><span>&nbsp;</span></p>]]></description>
	<dc:creator>BioStar</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/22352/affy-has-acquired-eureka-genomics-for-15m</guid>
	<pubDate>Wed, 20 May 2015 15:11:20 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/22352/affy-has-acquired-eureka-genomics-for-15m</link>
	<title><![CDATA[Affy has acquired Eureka Genomics for 15M $]]></title>
	<description><![CDATA[<p>Affymetrix Acquires Assets Of Eureka Genomics Corporation To Provide High Throughput And Economical Crop And Animal Genotyping</p><p>http://www.thestreet.com/story/13151062/1/affymetrix-acquires-assets-of-eureka-genomics-corporation-to-provide-high-throughput-and-economical-crop-and-animal-genotyping.html</p>]]></description>
	<dc:creator>Martin Jones</dc:creator>
</item>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/44503/entire-human-genome-sequencing</guid>
	<pubDate>Tue, 02 Apr 2024 01:19:29 -0500</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/44503/entire-human-genome-sequencing</link>
	<title><![CDATA[Entire Human Genome Sequencing !]]></title>
	<description><![CDATA[<p>Cost-effective whole human genome sequencing has revolutionized the landscape of genetic research and personalized medicine by making comprehensive genetic analysis accessible to a wider population. Through advancements in sequencing technologies, such as next-generation sequencing (NGS), costs have significantly decreased, enabling researchers and healthcare providers to analyze an individual's complete genetic makeup with greater efficiency and affordability. This has profound implications for disease diagnosis, prognosis, and treatment, as it allows for the identification of genetic predispositions and the customization of healthcare interventions based on an individual's unique genetic profile. Moreover, as the cost continues to decline, the potential for population-scale genomic studies and large-scale screening programs becomes increasingly feasible, promising to further enhance our understanding of human genetics and improve healthcare outcomes on a global scale.</p><p>Here are few companies:</p><p>https://mynucleus.com/</p><p>https://myome.com/</p><p>https://nebula.org/whole-genome-sequencing-dna-test/</p>]]></description>
	<dc:creator>LEGE</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/22402/alessandra-carbone-lab</guid>
  <pubDate>Tue, 26 May 2015 08:54:34 -0500</pubDate>
  <link></link>
  <title><![CDATA[Alessandra Carbone Lab]]></title>
  <description><![CDATA[
<p>Our group works on various problems connected with the functioning and evolution of biological systems. We use mathematical tools, coming from statistics and combinatorics, algorithmic tools and molecular physics tools to study basic principles of cellular functioning starting from genomic data. We run several projects in parallel, all aiming at understanding the basic principles of evolution and co-evolution of molecular structures in the cell. They are intimately linked to each other.</p>

<p>Our main research themes are:</p>

<p>Domain annotation and metagenomics <br />Transcriptomics and sequence analysis<br />Protein evolution and interactions<br />Protein conformational dynamics</p>

<p>More at http://www.lcqb.upmc.fr/AnalGenom/home.html</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/44754/early-genome-screening-the-new-health-horoscope</guid>
	<pubDate>Thu, 02 Jan 2025 19:44:36 -0600</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/44754/early-genome-screening-the-new-health-horoscope</link>
	<title><![CDATA[Early Genome Screening: The New Health Horoscope!]]></title>
	<description><![CDATA[<p>In an era where precision medicine is reshaping healthcare, genome screening is emerging as the modern equivalent of a health horoscope. It offers insights into our biological "stars," unraveling predispositions to various conditions and empowering individuals with knowledge to navigate their health journeys proactively. But how reliable is this "horoscope," and how does it impact our lives?</p><h3>Understanding Genome Screening</h3><p>Genome screening involves analyzing an individual's DNA to identify genetic variations that may influence health and disease susceptibility. This can range from simple single-gene tests to comprehensive whole-genome sequencing. By peering into our genetic blueprint, we can uncover risks for conditions like cancer, diabetes, cardiovascular diseases, and even rare genetic disorders.</p><p>The process is straightforward: a saliva or blood sample is collected, and advanced sequencing technologies decipher the genetic code. The results provide a personalized health map, guiding lifestyle modifications, preventive measures, or medical interventions.</p><h3>A Shift from Reactive to Proactive Healthcare</h3><p>Traditional healthcare often focuses on treating diseases after they manifest. Genome screening flips this model on its head, enabling a shift toward prevention and early intervention. For instance:</p><ul>
<li>
<p><strong>Cancer Risk Management</strong>: Individuals with BRCA1 or BRCA2 gene mutations can opt for enhanced screening programs or preventive surgeries to mitigate their risk of breast and ovarian cancers.</p>
</li>
<li>
<p><strong>Cardiovascular Health</strong>: Genetic predispositions to conditions like familial hypercholesterolemia can prompt early cholesterol monitoring and lifestyle adjustments.</p>
</li>
<li>
<p><strong>Rare Diseases</strong>: Identifying carriers of genetic disorders can aid in family planning and reduce the incidence of inherited conditions.</p>
</li>
</ul><h3>The Ethical and Practical Concerns</h3><p>While genome screening offers incredible promise, it is not without challenges:</p><ol>
<li>
<p><strong>Accuracy and Interpretation</strong>: Genetic predisposition does not guarantee disease. Misinterpretation of results can lead to unnecessary anxiety or unwarranted medical interventions.</p>
</li>
<li>
<p><strong>Privacy and Data Security</strong>: Genetic data is highly sensitive. Ensuring robust data protection measures is crucial to prevent misuse.</p>
</li>
<li>
<p><strong>Accessibility and Equity</strong>: High costs and limited availability may restrict access to genome screening, exacerbating health disparities.</p>
</li>
</ol><h3>Balancing Science and Pseudoscience</h3><p>The comparison of genome screening to horoscopes isn&rsquo;t entirely unfounded. Both offer predictive insights, but the scientific foundation of genome screening distinguishes it from astrology. Unlike the alignment of celestial bodies, genetic predictions are based on rigorous data and evidence. However, the probabilistic nature of genetic predispositions underscores the importance of interpreting results in conjunction with clinical and lifestyle factors.</p><h3>The Road Ahead</h3><p>As genome screening becomes more affordable and integrated into routine healthcare, its potential to transform lives is immense. Policymakers, healthcare providers, and genetic counselors must collaborate to ensure ethical implementation, public awareness, and equitable access.</p><p>Imagine a future where your genetic "horoscope" is a trusted guide, not just a prediction. Early genome screening could help chart a healthier path for generations, making it a cornerstone of personalized medicine. After all, our genes might just hold the key to unlocking a future of better health and well-being.</p><p>&nbsp;</p>]]></description>
	<dc:creator>LEGE</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/22414/x-shirley-liu-lab</guid>
  <pubDate>Tue, 26 May 2015 17:28:23 -0500</pubDate>
  <link></link>
  <title><![CDATA[X. Shirley Liu Lab]]></title>
  <description><![CDATA[
<p>The research in our laboratories are focused on the following three areas: </p>

<p>Bioinformatics<br />Cancer<br />Epigenetics</p>

<p>More at http://liulab.dfci.harvard.edu/</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/45240/pg2-making-pangenome-graphs-easier-to-understand</guid>
	<pubDate>Tue, 18 Aug 2026 04:38:23 -0500</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/45240/pg2-making-pangenome-graphs-easier-to-understand</link>
	<title><![CDATA[PG2: Making Pangenome Graphs Easier to Understand]]></title>
	<description><![CDATA[<p>Genomics is moving beyond the traditional approach of studying DNA using a single reference genome. Today, researchers are increasingly using pangenomes, which represent genetic information from multiple genomes and capture a much broader range of genetic diversity.</p><p>However, pangenome graphs can be highly complex, making them difficult to visualize and interpret. A recent study published in BMC Bioinformatics introduces PG2 (PanGenoGrapher), an open-source, web-based tool designed to address this challenge.&nbsp;The source code and user guide are openly available on GitHub at https://github.com/iVis-at-Bilkent/pangenographer. A publicly accessible sample deployment is hosted at http://pg2.cs.bilkent.edu.tr. In addition, a demonstration video illustrating the primary use cases of PG2 is available at https://www.youtube.com/watch?v=yCd7-aGY6CQ.</p><p>PG2 combines advanced graph-layout algorithms with an interactive visualization platform. It allows researchers to explore genomic paths, identify variations, and examine relationships between different parts of a pangenome graph more easily.</p><p>This is important because visualization can play a major role in bioinformatics. When complex genomic information is presented clearly, researchers can more easily identify patterns, understand genetic variation, and generate new biological insights.</p><p>The development of PG2 represents a step toward making pangenome analysis more accessible and intuitive. As genomic datasets continue to grow and graph-based representations become more common, tools like PG2 can help researchers navigate this increasing complexity.</p><p>Ultimately, PG2 demonstrates how combining genomics, graph algorithms, and interactive visualization can make sophisticated biological data easier to understand and analyze.</p><p>Reference: Solun, G. K., Dogrusoz, U., Bing&ouml;l, Z., &amp; Alkan, C. (2026). PG2: algorithms and a web-based tool for effective layout and visual analysis of pangenome graphs. BMC Bioinformatics. DOI: 10.1186/s12859-026-06555-4.</p>]]></description>
	<dc:creator>Jitendra Narayan</dc:creator>
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