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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/29679?offset=760</link>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/42324/comparative-genomics-data-set-including-240-mammals-released</guid>
	<pubDate>Thu, 19 Nov 2020 06:45:39 -0600</pubDate>
	<link>https://bioinformaticsonline.com/news/view/42324/comparative-genomics-data-set-including-240-mammals-released</link>
	<title><![CDATA[Comparative Genomics Data Set Including 240 Mammals Released !]]></title>
	<description><![CDATA[<p>The genome of 130 mammals was sequenced by a large international consortium and the data was analyzed together with 110 existing genomes to allow scientists to identify the important positions in the DNA. This report, published in Nature today will help advance research on human disease mutations and inform how best to protect endangered species.</p><p>In addition to the knowledge of the human genome, all these genomes, widely sampled across mammals, can be used to research how particular organisms respond to different conditions. Some otters, for example, have a thick, water-resistant shell, and some rodents, but not all, have adapted to hibernation. These animal traits will help us to understand human traits, such as metabolic diseases.</p><p><img src="https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41586-020-2876-6/MediaObjects/41586_2020_2876_Fig1_HTML.png?as=webp" alt="image" style="border: 0px; border: 0px;"></p><p>With climate change and more animal ecosystems being threatened by human activity, the protection of endangered species is becoming increasingly important. Scientists have historically researched several people in various populations of a species to understand the genetic variation that occurs in that species. This is important for understanding how particular species can be protected. In this study, animals on the Red List of Endangered Species of the International Union for Conservation of Nature had fewer differences in their genomes, which is consistent with their endangered status.</p><p>Ref @&nbsp;A comparative genomics multitool for scientific discovery and conservation&nbsp;https://www.nature.com/articles/s41586-020-2876-6</p><p>&nbsp;Data at&nbsp;http://zoonomiaproject.org/</p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/43362/machine-learning-for-genomics</guid>
	<pubDate>Thu, 09 Sep 2021 11:26:32 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/43362/machine-learning-for-genomics</link>
	<title><![CDATA[Machine Learning for Genomics]]></title>
	<description><![CDATA[<h3>Module 1: Statistics for genomics (2-8 August 2021)</h3>
<ul>
<li>A simple intro to statistical distributions</li>
<li>hypothesis testing</li>
<li>linear models.</li>
</ul>
<p>reading:&nbsp;<a href="http://compgenomr.github.io/book/stats.html">http://compgenomr.github.io/book/stats.html</a></p>
<p>slides:&nbsp;<a href="https://github.com/BIMSBbioinfo/compgen2021/tree/main/week1/compgen2021_stats.pdf">https://github.com/BIMSBbioinfo/compgen2021/tree/main/week1/compgen2021_stats.pdf</a></p>
<p>exercises+code:&nbsp;<a href="https://github.com/BIMSBbioinfo/compgen2021/tree/main/week1/">https://github.com/BIMSBbioinfo/compgen2021/tree/main/week1/</a></p>
<h3><a href="https://github.com/BIMSBbioinfo/compgen2021#module-2-unsupervised-learning-for-genomics-9-15-august-2021"></a>Module 2: Unsupervised learning for genomics (9-15 August 2021)</h3>
<ul>
<li>Understanding basic intuition behind machine learning approaches.</li>
<li>Using unsupervised learning to cluster and visualise data points</li>
<li>Dimension reduction techniques for visualisation and as input to clustering methods</li>
</ul>
<p>reading:&nbsp;<a href="http://compgenomr.github.io/book/unsupervisedLearning.html">http://compgenomr.github.io/book/unsupervisedLearning.html</a></p>
<p>slides:&nbsp;<a href="https://github.com/BIMSBbioinfo/compgen2021/tree/main/week2/compgen2021_unsupervisedLearning.pdf">https://github.com/BIMSBbioinfo/compgen2021/tree/main/week2/compgen2021_unsupervisedLearning.pdf</a></p>
<p>exercises+code:&nbsp;<a href="https://github.com/BIMSBbioinfo/compgen2021/tree/main/week2/">https://github.com/BIMSBbioinfo/compgen2021/tree/main/week2/</a></p>
<h3><a href="https://github.com/BIMSBbioinfo/compgen2021#module-3-supervised-learning-for-genomics-16-22-august-2021"></a>Module 3: Supervised learning for genomics (16-22 August 2021)</h3>
<ul>
<li>Understanding and using supervised learning methods for predictive purposes</li>
<li>How to measure prediction performance</li>
<li>Understand and use cross-validation and related concepts</li>
</ul>
<p>reading:&nbsp;<a href="http://compgenomr.github.io/book/supervisedLearning.html">http://compgenomr.github.io/book/supervisedLearning.html</a></p>
<p>slides:&nbsp;<a href="https://github.com/BIMSBbioinfo/compgen2021/tree/main/week3/compgen2021_supervisedLearning.pdf">https://github.com/BIMSBbioinfo/compgen2021/tree/main/week3/compgen2021_supervisedLearning.pdf</a></p>
<p>exercises+code:&nbsp;<a href="https://github.com/BIMSBbioinfo/compgen2021/tree/main/week3/">https://github.com/BIMSBbioinfo/compgen2021/tree/main/week3/</a></p>
<p>https://github.com/BIMSBbioinfo/compgen2021</p><p>Address of the bookmark: <a href="https://github.com/BIMSBbioinfo/compgen2021" rel="nofollow">https://github.com/BIMSBbioinfo/compgen2021</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/videolist/watch/18381/how-far-can-bioinformatics-go-creating-organisms-used-for-testing</guid>
	<pubDate>Fri, 17 Oct 2014 02:08:16 -0500</pubDate>
	<link>https://bioinformaticsonline.com/videolist/watch/18381/how-far-can-bioinformatics-go-creating-organisms-used-for-testing</link>
	<title><![CDATA[How far can bioinformatics go creating organisms used for testing?]]></title>
	<description><![CDATA[<iframe width="" height="" src="https://www.youtube-nocookie.com/embed/FojhDef2NW4" frameborder="0" allowfullscreen></iframe>"I think you can get very far on a technical level. The problem is that a human body is more complex than just one cell." ... "At some point we still need clinical tests on animals and humans before we use it for real treatment. But we will likely be able to remove 99 % of animal tests in the future."

Erik Lindahl, Professor of Theoretical and Computational Biophysics at KTH Royal Institute of Technology is telling us about his work.

From the episode "Science for life – mapping the building blocks of the human body". Watch the rest of the talk, and other talks at www.crosstalks.tv

Crosstalks is an academic talkshow produced by KTH Royal Institute of Technology and Stockholm University.]]></description>
	
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/44650/manthey-research-group-%E2%80%93-evolutionary-genomics</guid>
  <pubDate>Thu, 22 Aug 2024 06:25:55 -0500</pubDate>
  <link></link>
  <title><![CDATA[Manthey Research Group – Evolutionary Genomics]]></title>
  <description><![CDATA[
<p>We focus on fundamental questions in genomics, ecology, and evolution. Our methods include fieldwork and labwork, but most of our time is spent analyzing genomics data using computational biology approaches.</p>

<p>Ant / bacteria co-evolution, landscape genomics, and population genomics<br />Vertebrate and/or invertebrate genome evolution</p>

<p>If you might be interested in joining our research group, send an email with your intent and why this group would potentially be a good fit for your future goals along with a CV / Resume to jdmanthey (at) gmail (dot) com</p>

<p>More at https://mantheylab.org/</p>
]]></description>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/18576/graduate-research-assistantships-university-of-nebraska-lincoln-unl</guid>
  <pubDate>Wed, 22 Oct 2014 10:05:31 -0500</pubDate>
  <link></link>
  <title><![CDATA[Graduate research assistantships @ University of Nebraska-Lincoln (UNL)]]></title>
  <description><![CDATA[
<p>Graduate research assistantships in quantitative genetics are available with Gota Morota in the Department of Animal Science at the University of Nebraska-Lincoln (UNL).</p>

<p>Current projects in the Morota lab include developing kernel-based whole-genome prediction and kernel-based genome-wide association models, polygenic modeling of binary traits, reexamining the results from quantitative genetics analysis in light of functional annotation, and extending kernel methods (such as GBLUP and RKHS) specifically tailored for diverse types of emerging omics data.</p>

<p>In addition, candidates will be expected to leverage opportunities to interact with faculty in animal genetics and biometrics at the UNL in the areas of bioinformatics, breeding, functional genomics, quantitative genetics, and molecular genetics.</p>

<p>Candidates should have a B.S. or M.S. degree in quantitative disciplines with strong background and interest in statistical computing. <br />The starting date is Fall 2015. <br />For more information about research in the Morota lab at the UNL, visit: http://www.morotalab.org</p>

<p>A letter of interest in the position, C.V., and contact information for <br />three references should be emailed to Gota Morota at . <br />Review of applications will begin immediately, and continue until the <br />positions are filled. Informal inquiries are also welcome.</p>

<p>Also, please see: http://animalscience.unl.edu/anscprospectivegraduatestudents</p>
]]></description>
</item>

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  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/45309/ley-lab</guid>
  <pubDate>Fri, 11 Sep 2026 13:21:10 -0500</pubDate>
  <link></link>
  <title><![CDATA[Ley Lab !]]></title>
  <description><![CDATA[
<p>Research Program aims to elucidate how gut microbial species relate to genotypic differences between human individuals, to identify bacterial and archaeal species that share an evolutionary history with humans, and to determine the molecular basis of long-term host-microbial relationships. We approach these aims through a combination of population-level observations and laboratory-based molecular-level investigations. We link inter-microbial and microbial-host interactions at the molecular scale to patterns at population and evolutionary scales. </p>

<p>More at https://leylab.com/</p>
]]></description>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/18820/jrfsrf-at-university-of-calcutta</guid>
  <pubDate>Fri, 31 Oct 2014 08:53:10 -0500</pubDate>
  <link></link>
  <title><![CDATA[JRF/SRF at University of Calcutta]]></title>
  <description><![CDATA[
<p>Applications are invited to appear at a walk-in-interview for one post of Junior Research Fellow in the DBT(DBT Twinning NER) sponsored project entitled “Protein folding kinetics is a selection force on shaping codon usage bias in the high expression genes” in the room of the HOD, Department of Biotechnology and the Coordinator, DR. B. C. Guha Centre for Genetic Engineering and Biotechnology, University College of Science, 35 Ballygunge Circular Road, Kolkata 700019 on the 12th November, 2014 at 3:00 p.m.</p>

<p>Essential qualifications: First class M. Sc. in any branch of life sciences and qualified CSIR-UGC NET/GATE Examination.</p>

<p>Desirable qualifications: Practical experience in biochemical and biophysical studies of proteins</p>

<p>Emoluments: as per DBT norms</p>

<p>The project is tenable for two years, initially for one year.</p>

<p>Age: Below 28 years (relaxable in the case of SC/ST/OBC/women candidates)</p>

<p>Candidates are requested to bring two sets of complete applications on plain paper furnishing bio-data and copies of attested certificates along with originals (for verification) on the date of interview.</p>

<p>No TA/DA is admissible for candidates appearing at the interview.</p>

<p>Dr. Rajat Banerjee<br />Assistant Professor<br />Department of Biotechnology and<br />Dr. B. C. Guha Centre for Genetic Engineering and Biotechnology<br />University College of Science<br />35, Ballygunge Circular Road<br />Kolkata 700019</p>

<p>Advertisement: www.caluniv.ac.in/news/jrf_biotech_2.pdf</p>
]]></description>
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<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/3885/precision-medicine</guid>
	<pubDate>Sat, 24 Aug 2013 15:47:03 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/3885/precision-medicine</link>
	<title><![CDATA[Precision Medicine]]></title>
	<description><![CDATA[<p>Coupling established clinical&ndash;pathological indexes with state-of-the-art molecular profiling to create diagnostic, prognostic, and therapeutic strategies precisely tailored to each patient's requirements &mdash; hence the term &ldquo;Precision medicine&rdquo;&nbsp;</p>
<p>Source:<a href="http://www.nejm.org/doi/full/10.1056/NEJMp1114866">http://www.nejm.org/doi/full/10.1056/NEJMp1114866</a></p>
<p><strong>Another video on precision medicine</strong>:</p>
<p><a href="http://www.youtube.com/watch?v=Pi8W0yOXnzE">http://www.youtube.com/watch?v=Pi8W0yOXnzE</a></p>
<p>Precision Medicine basically intergrates bioinformatics, genomics , genetics, molecular biology and nanotechnology to deliver precise cure/diagnotics to a specific patient.</p>
<p>Examples:</p>
<ul>
<li><span>The drug imatinib (Gleevec) designed to inhibit an altered enzyme produced by a fused version of two genes found in chronic myelogenous leukemia.</span></li>
<li><span>The breast cancer drug trastuzumab (Herceptin) works only for women whose tumors have a particular genetic profile called HER-2 positive.</span></li>
</ul>
<p><span>E.g. source :</span></p>
<p><span><a href="http://www.bionews-tx.com/news/2013/08/15/how-the-impact-of-cancer-genomics-on-precision-medicine-is-revolutionizing-cancer-treatment/">http://www.bionews-tx.com/news/2013/08/15/how-the-impact-of-cancer-genomics-on-precision-medicine-is-revolutionizing-cancer-treatment/</a></span></p><p>Address of the bookmark: <a href="http://www.cbsnews.com/video/watch/?id=50149783n" rel="nofollow">http://www.cbsnews.com/video/watch/?id=50149783n</a></p>]]></description>
	<dc:creator>Rahul Agarwal</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/19085/jrf-in-bioinformatics-pondicherry-university</guid>
  <pubDate>Sat, 08 Nov 2014 14:34:48 -0600</pubDate>
  <link></link>
  <title><![CDATA[JRF in Bioinformatics @ Pondicherry University]]></title>
  <description><![CDATA[
<p>Eager to get JRF job in Puducherry? Pondicherry University, School of Life Sciences, Centre for Bioinformatics has issued notification to fill the vacancy of JRF for DST sponsored research project entitled "Design and discovery of aurora kinase inhibitors as anti cancer drugs; application of computer aided drug design". It is good chance to get job with Pondicherry University and secure your future. Learn eligibility criteria and apply on or before 21.11.2014.</p>

<p>Required Skills:	no special skills required for this job post<br />Required Experience:	<br />Experience in computer aided drug design and or biochemical testing of natural or synthetic compounds is desired<br />Required Education:	<br />M.Sc. / M.Tech.</p>

<p>Required Job Profile:<br />Candidate must possess M.Sc. in bioinformatics or computational biology or biotechnology or any branch of life sciences or pharmacology or chemical sciences or M.Tech. in any branch of life sciences with at least fifty five percent marks with NET or GATE.</p>

<p>Desired Job Profile:<br />Candidate having experience in computer aided drug design and or biochemical testing of natural or synthetic compounds.</p>

<p>How to apply:<br />Eligible and interested candidates should need to appear for walk-in interview on 21.11.2014 at 1700 hrs at the above mentioned address.</p>

<p>Contact<br />Pondicherry University<br />Dr. S. Mohane Coumar, Assistant Professor &amp; Project Investigator, Centre for Bioinformatics, Pondicherry University, Puducherry 605 014<br />Email:registrar@pondiuni.edu.in<br />Phone:	0413-2655175</p>

<p>More at http://www.pondiuni.edu.in/sites/default/files/JRF-bioinfor-041114.pdf</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/34485/phyloxml-xml-for-evolutionary-biology-and-comparative-genomics</guid>
	<pubDate>Wed, 29 Nov 2017 10:04:48 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/34485/phyloxml-xml-for-evolutionary-biology-and-comparative-genomics</link>
	<title><![CDATA[phyloXML:  XML for evolutionary biology and comparative genomics]]></title>
	<description><![CDATA[<p><a href="http://www.biomedcentral.com/1471-2105/10/356/">phyloXML</a><span>&nbsp;(</span><a href="http://www.phyloxml.org/examples_syntax/phyloxml_syntax_example_1.html">example</a><span>) is an&nbsp;</span><a href="http://en.wikipedia.org/wiki/XML">XML</a><span>&nbsp;language designed to describe phylogenetic trees (or networks) and associated data. PhyloXML provides elements for commonly used features, such as taxonomic information, gene names and identifiers, branch lengths, support values, and gene duplication and speciation events. Using these standardized elements allows interoperability between various applications and databases. Furthermore, both due to extensible nature of XML itself and the provision of &lt;property&gt; elements by phyloXML, extensibility as well as domain specific applications are ensured. The structure of phyloXML is described by&nbsp;</span><a href="http://en.wikipedia.org/wiki/XML_Schema_%28W3C%29">XML Schema Definition (XSD)</a><span>&nbsp;language.</span></p><p>Address of the bookmark: <a href="http://www.phyloxml.org/" rel="nofollow">http://www.phyloxml.org/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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