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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/29683?offset=1120</link>
	<atom:link href="https://bioinformaticsonline.com/related/29683?offset=1120" rel="self" type="application/rss+xml" />
	<description><![CDATA[]]></description>
	
	
<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/5663/network-analysis-indian-statistical-institute</guid>
  <pubDate>Wed, 16 Oct 2013 08:06:50 -0500</pubDate>
  <link></link>
  <title><![CDATA[Network Analysis @ Indian Statistical Institute]]></title>
  <description><![CDATA[
<p>Indian Statistical Institute Kolkata invites applications for the following posts</p>

<p>2013 Oct Advertisement from Indian Statistical Institute</p>

<p>Post: Network Analysis</p>

<p>No. of Positions:  01</p>

<p>Educational Qualifications:</p>

<p>Candidate should have passed BE/B.Tech Or Equivalent in Computer Science / Electrical Engineering / Electronics / Information Technology / Bioinformatics / Biotechnology with throughout first Class<br />Experience:</p>

<p>(details of experience required)<br />Pay Scale: INR Rs.16000-20000/-P.M.</p>

<p>Walk-In-Interview : 22 Oct 2013 at 10:30 AM</p>

<p>Download Official Notification:<br />http://www.isical.ac.in/JobApplicationFiles/MIU_0310201311433700.pdf</p>
]]></description>
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<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/5957/assistant-professor-in-molecular-synthesis-for-drug-discovery-and-development-cbmr-lucknow</guid>
  <pubDate>Wed, 30 Oct 2013 06:42:27 -0500</pubDate>
  <link></link>
  <title><![CDATA[Assistant Professor in Molecular Synthesis for Drug Discovery and Development @ CBMR, Lucknow]]></title>
  <description><![CDATA[
<p>ADVERTISEMENT FOR FACULTY POSITIONS AT CENTRE OF BIOMEDICAL RESEARCH (CBMR), LUCKNOW</p>

<p>Details of the Positions and Pay Structure:</p>

<p>03 Posts for Assistant Professor in Molecular Synthesis for Drug Discovery and Development</p>

<p>Essential Qualifications and Requirements:</p>

<p>1. PhD in Synthetic Organic Chemistry/Medicinal Chemistry with research publications in high quality international journals and first class grade at the preceding degree from recognised University/Institute in India or abroad with consistently good academic record.<br />2. Three Yrs of Post-doctoral experience in relevant area.<br />3. Below 35 Yrs of age at the time of application</p>

<p>Desirable Experience: Candidates having strong research background in organic synthesis, total synthesis of structurally complex and medicinally important natural products/drugs related to cancer, neurodegenerative diseases (neurotropically active molecules for Alzheimer's, Parkinson’s, dementia etc) and infectious diseases such as malaria, TB etc. will be preferred.</p>

<p>Interested candidates may apply with:</p>

<p>1. Filled up Application Form (download from CBMR Website: http://www.cbmr.res.in) along with the Cover Letter, Curriculum Vitae including academic record (Bachelor degree onwards), awards, honours, list of Publications and reprints of 5 best publications.<br />2. Proposed research plan (max 3-4 pages).<br />3. Names and address (with valid e-mail and Phone number) of at least 3 academic referees.<br />4. Online Payment Receipt with transaction reference no. of Rs. 1000/- (USD 100 or equivalent foreign currency) on following details.<br />Account Number: 30054847814 Name: Director, Centre of Biomedical Research<br />Bank: STATE BANK OF INDIA, SGPGI Campus Branch, LUCKNOW</p>

<p>IFSC Code: SBIN0007789<br />MICR No: 22602034</p>

<p>Applications can be sent by registered/speed post or by e-mail to the following address:</p>

<p>The Director,<br />Centre of Biomedical Research (CBMR),<br />Sanjay Gandhi PGI Campus,<br />Raebareli Road, Lucknow-226014<br />e-mail: cbmr.admin@cbmr.res.in,<br />gp.pandey@cbmr.res.in</p>

<p>More Info:</p>

<p>http://www.cbmr.res.in/career/Advertisement%20for%20the%20post%20of%20Professors%20and%20Assistant%20Professors.pdf</p>
]]></description>
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<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/24041/junior-bioinformatic-position</guid>
  <pubDate>Wed, 26 Aug 2015 05:35:28 -0500</pubDate>
  <link></link>
  <title><![CDATA[Junior Bioinformatic position]]></title>
  <description><![CDATA[
<p>Junior Bioinformatic position in the laboratory of Inflammation and immunology in cardiovascular pathologies at Humanitas:</p>

<p>We are seeking a highly motivated young PhD student with strong interest in high throughput data analysis.<br />Detailed descriptions of our recent research activities may be found here:<br />http://www.humanitas-research.org/condorelli-gianluigi-md-phd/</p>

<p>Position is available starting from October/November. A probationary period of one month will be required.<br /> <br />Please send a CV along with a cover letter stating the reasons for applying and contact details of one or more referees to Dr. Paolo Kunderfranco (paolo.kunderfranco@humanitasresearch.it).</p>
]]></description>
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<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/videolist/watch/4962/bionics-transhumanism-and-the-end-of-evolution-full-documentary</guid>
	<pubDate>Fri, 27 Sep 2013 11:54:17 -0500</pubDate>
	<link>https://bioinformaticsonline.com/videolist/watch/4962/bionics-transhumanism-and-the-end-of-evolution-full-documentary</link>
	<title><![CDATA[Bionics, Transhumanism, and the end of Evolution (Full Documentary)]]></title>
	<description><![CDATA[<iframe width="" height="" src="https://www.youtube-nocookie.com/embed/cU1-YFbAifA" frameborder="0" allowfullscreen></iframe>Bionics, Transhumanism, and the end of Evolution (Full Documentary) .                        
                       
                        
                          
                              
                               
                            
                                        
2013                                                                        
This documentary and the rest of the documentaries presented relate to important times and figures in history, historic places and sites, archaeology, science, conspiracy theories, and education.  
The Topics of these video documentaries are varied and cover ancient history, Rome, Greece, Egypt, science, technology, nature, planet earth, the solar system, the universe, World wars, Battles, education, Biographies, television, archaeology, Illuminati, Area 51, serial killers, paranormal, supernatural, cults, government cover-ups, corruption, martial arts, space, aliens, ufos, conspiracy theories, Annunaki, Nibiru, Nephilim, satanic rituals, religion, strange phenomenon, origins of Mankind]]></description>
	
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/6268/project-fellow-national-institute-of-malaria-research</guid>
  <pubDate>Tue, 12 Nov 2013 07:40:51 -0600</pubDate>
  <link></link>
  <title><![CDATA[Project Fellow @ National Institute of Malaria Research]]></title>
  <description><![CDATA[
<p>National Institute of Malaria Research</p>

<p>Sector 8, Dwarka, Delhi -110077</p>

<p>WALK IN INTERVIEW</p>

<p>One position of project fellow is to be filled up in a DRL- funded research project on Molecular and morphological characterization of An. fluviatilis in North-eastern states and bordering areas. The position is purely temporary for one year and can be extended</p>

<p>Essential qualifications</p>

<p>Master’s degree in any branch of Life Sciences with hands on experience in molecular biology and/or bioinformatics.</p>

<p>Age limit: 28 years, (relaxation for SC/ST/OBC candidates as per government of India rules)</p>

<p>Stipend: Rs.12, 000.00 per month (fixed)</p>

<p>Eligible candidates may walk in for an interview on 15 November 2013 at 11 AM at the above mentioned address along with a copy of CV (with a passport size photograph affixed), photocopies of all mark sheets/certificates and originals (for verifications). No TA/DA will be paid for attending the interview .Registration of candidates will start at 10:00AM and end at 10:45 AM.</p>

<p>Advertisement: http://www.mrcindia.org/vacancy/add-4.doc</p>
]]></description>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/26234/manolis-kellis-lab</guid>
  <pubDate>Sun, 31 Jan 2016 20:51:06 -0600</pubDate>
  <link></link>
  <title><![CDATA[Manolis Kellis Lab]]></title>
  <description><![CDATA[
<p>A major focus of our lab is understanding the effects of genetic variation on molecular phenotypes and human disease. We develop methods for integrating diverse functional genomic datasets of transcription, chromatin modifications, regulator binding, and their changes across multiple conditions to interpret genetic associations, identify causal variants, and predict the effects of genetic perturbations.</p>

<p>More at http://compbio.mit.edu</p>
]]></description>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/6560/the-graveley-lab</guid>
  <pubDate>Tue, 19 Nov 2013 18:02:48 -0600</pubDate>
  <link></link>
  <title><![CDATA[The Graveley Lab]]></title>
  <description><![CDATA[
<p>Research in the Graveley lab is primarily focused on the regulation of alternative splicing and small RNA mediated gene regulation. These are fascinating and extraordinarily important mechanisms by which genes can be regulated. Our long-term goals are to understand how these processes are regulated at a mechanistic level and to understand the logic of these processes in significant biological settings. To achieve these goals, we strive to think outside the box to creatively attack the problems being addressed using a wide variety of approaches that include biochemistry, genetics, imaging, deep sequencing, large-scale RNAi screening and bioinformatics.</p>

<p>Lab page @ http://graveleylab.cam.uchc.edu/Graveley/index.html</p>
]]></description>
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<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/7153/phd-student-in-computational-systems-biology</guid>
  <pubDate>Tue, 10 Dec 2013 18:46:05 -0600</pubDate>
  <link></link>
  <title><![CDATA[Ph.D. student in Computational Systems Biology]]></title>
  <description><![CDATA[
<p>Ph.D. student in Computational Systems Biology</p>

<p>Location : The Luxembourg Centre for Systems Biomedicine (LCSB) at the University of Luxembourg, Luxembourg, Luxembourg<br />Deadline for applications : unknown.<br />Description :</p>

<p>The Luxembourg Centre for Systems Biomedicine (LCSB) was created within the Health Technologies Initiative from the Government of Luxembourg as one of the research priorities of the University of Luxembourg. The LCSB is an Interdisciplinary Centre of the University that combines experimental and computational approaches to analyse complex biological systems and disease processes. The Computational Biology Group (CBG) provides the LCSB with a solid infrastructure in developing theoretical framework for computational modeling on biomedical problems, especially in the area of network biology in the context of cellular programming/reprogramming. The CBG group includes researchers with theoretical, computational and wet lab backgrounds, thereby providing an unusually interdisciplinary environment.<br />The Computational Biology Group seeks a highly-skilled Ph.D. student to work on an exciting project on reconstruction and analysis of an integrated gene regulatory network model to elucidate key mechanisms of cellular reprogramming. The model will rely on the integration and mining of diverse transcriptomics and epigenomics data of different cell types from the Central Nervous System. The Ph.D. student is expected to collaborate with other members of the CBG to develop a computational methodology aiming at designing, in-silico, cellular reprogramming events, with a focus on the nervous system. This project will be carried out in collaboration with Prof. Noel Buckleys lab at Kings College London.<br />Requirements of the ideal candidate:<br />Master degree in Bioinformatics, Computer Science, Biology or a related discipline<br />Prior experience in mathematical modelling of biological networks, especially in network inference and analysis<br />Excellent working knowledge in English.<br />.<br />We offer:<br />Full contract for Ph.D. student for three years with possibility of renewal<br />Opportunity to do applied research to medical problems within a highly dynamic research institution (LCSB) and in collaboration with internationally recognized partners<br />An exciting international environment<br />A very competitive salary</p>

<p>For further information, please contact:</p>

<p>Prof. Dr. Antonio del Sol<br />E-mail: antonio.delsol@uni.lu</p>

<p>Applications should contain the following documents:<br />A detailed curriculum vitae<br />cover letter mentioning the reference number<br />description of past research experience and future interests<br />name and addresses of three referees</p>

<p>All applications should be sent preferably in electronic version until December 31st, 2013 to the following address:</p>

<p>Luxembourg Centre for Systems Biomedicine (LCSB)<br />University of Luxembourg<br />7, avenue des Hauts-Fourneaux<br />L-4362 Esch-sur-Alzette<br />Tel: +352-466644-6982 (Office)<br />Email: antonio.delsol@uni.lu<br />http://www.lcsb.lu</p>
]]></description>
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<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/44614/online-resources-on-must-read-papers-in-evolutionary-biology</guid>
	<pubDate>Fri, 26 Jul 2024 01:39:14 -0500</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/44614/online-resources-on-must-read-papers-in-evolutionary-biology</link>
	<title><![CDATA[Online resources on must-read papers in evolutionary biology]]></title>
	<description><![CDATA[<pre>Online resources on must-read papers in evolutionary biology, for a literature club.<br /><br />Below is a summary of all answers that we received.

All the best,

Jana and Xiaoyan

1.       *Nick Barton:*

- The textbook "Evolution" by Nick Barton, with resources for
  exploring the literature: Barton, N. H., Briggs, D. E. G., Eisen, J.
  A., Goldstein, D. B., &amp; Patel, N. H. (2007). Evolution. Cold Spring
  Harbor Laboratory Press.

- Papers from a course named "Classics in Evolutionary Biology":

Evolutionary Synthesis
1. Haldane, J. B. S. 1932. The causes of evolution. Longmans. New York.
   (esp. Ch. IV).
2. Fisher, R. A. 1930. The genetical theory of natural selection. Oxford
   University Press, Oxford. Selected Sections - Fundamental Theorem.

Genetic Variation
1a. Lewontin, R. C., and J. L. Hubby. 1966. A molecular approach to
the study of genic heterozygosity in natural populations. II. Amount
of variation and degree of heterozygosity in natural populations of
Drosophila pseudoobscura. Genetics. 54:595-609.

1b. Sachidandam et al. 2001. A map of human genome sequence variation
containing 1.42 million single nucleotide polymorphisms. 409: 928-33.

2. Wright S., Dobzhansky T., Hovanitz W. 1942 Genetics of natural
populations VII The allelism of lethals in the third chromosome of
Drosophila pseudoobscura. Genetics 27: 363-394.

Recombination and evolution
1. Hill, W. G., and A. Robertson. 1966. The effect of linkage on limits
to artificial selection. Genet. Res. 8:269-294.

2. Maynard Smith and Haigh. 1974. The hitch-hiking effect of a favourable
gene. Genet. Res. 23: 23-35.

Understanding sequence variation
1. Begun D. J., Aquadro C. F., 1992 Levels of naturally occurring DNA
polymorphism correlate with recombination rate in Drosophila melanogaster.
Nature 356: 519-520.

2. Green R. E., Reich D., P&auml;&auml;bo S., 2010 A draft sequence of the
Neandertal genome. Science 328: 710-722.

Quantitative Genetics:  variation in complex traits
1. Galton F., 1877 Typical laws of heredity. Nature 15: 492-495-
512-514- 532-533.

2. Turelli M., 1984 Heritable genetic variation via
mutation-selection balance: Lerch's Zeta meets the abdominal
bristle. Theor. Popul. Biol. 25: 138-193.

Quantitative Genetics:  finding the genes
1. Shrimpton A. E., Robertson A., 1988 The Isolation of polygenic factors
controlling bristle score in Drosophila melanogaster II Distribution of
third chromosome bristle effects within chromosome sections. Genetics
118: 445-459.

2. Boyle E. A., Li Y. I., Pritchard J. K., 2017 An expanded view of
complex traits: from polygenic to omnigenic. Cell 169: 1177-1186.

Neutral Evolution
1. Kimura, M. 1968. Evolutionary rate at the molecular level. Science.
217:624-626.

2a. Kern A. D., Hahn M. W., 2018 The Neutral Theory in Light of Natural
Selection. Molecular Biology and Evolution 110: 21077-6.

2b. Jensen J. D., Payseur B. A., Stephan W., Aquadro C. F., Lynch M.,
Charlesworth D., Charlesworth B., 2018 The importance of the Neutral Theory
in 1968 and 50 years on: a response to Kern and Hahn 2018. Evolution 112:
2109-4.

2c. Ellegren &amp; Galtier. 2016. Determinants of genetic diversity. Nature
Reviews Genetics.

Mutation and Genetic Variability
1. Luria, S. E., and M. Delbr&uuml;ck. 1943. Mutations of Bacteria from Virus
Sensitivity to Virus Resistance. Genetics. 28(6):491-511.

2. Hill, W G. 1982. "Rates of Change in Quantitative Traits From Fixation
of New Mutations." Proceedings of the National Academy of Sciences (U.S.A.)
79: 142-45.

Testing for selection
1. McDonald &amp; Kreitman. 1991. Adaptive protein evolution at the Adh locus
in Drosophila. Nature.

2. Begun, et al. Mol. Biol. Evol. 16, 1816-1819 (1999).

3. Siddiq et al. 2016. Experimental test and refutation of a classic case
of molecular adaptation in Drosophila melanogaster.  Nature Ecology &amp;
Evolution.

The shifting balance
1. Wright, S. 1932. The roles of mutation, inbreeding, crossbreeding and
selection in evolution. Proceedings of the VI International Congress of
Genetics: 1. pp 356-366.

2. Coyne, J.A., N.H. Barton, and M. Turelli. 1997. A critique of Wright's
shifting balance theory of evolution.  Evolution 51: 643-671.

3. Barton. 2016. Sewall Wright on Evolution in Mendelian Populations and
the "Shifting Balance". Genetics.

Evolution of Sex
1.  Muller, H.J. 1964. The relation of recombination to mutational advance.
Mutation Res. 1(1):2-9

2. McDonald et al. 2016. Sex speeds adaptation by altering the dynamics of
molecular evolution. Nature.

Kin Selection, Cooperation, and Conflict
1. Hamilton, W. D. 1964. The genetical evolution of social behaviour I.
Journal of Theoretical Biology. 7:1-52.

2. Trivers, R. L. 1974 Parent-offspring conflict. American Zoologist.
14(1):249-264.

Sexual Selection
1. Zahavi, A. 1975. Mate selection - a selection of a handicap. J. Theor.
Biol. 53:205-214.

2. Kirkpatrick, M., and Ryan, M.J. 1991. The evolution of mating
preferences and the paradox of the lek. Nature. 350:33-38.

Fitness Landscapes
1. Dean, A. 1995. A Molecular Investigation of Genotype by Environment
Interactions. Genetics. 139:19-33.

2. Costanzo et al. 2010. The Genetic Landscape of a Cell. Science.

Speciation
1. Coyne, J. A., and H. A. Orr. 1989. Patterns of speciation in Drosophila.
Evolution. 43:362-381.

2. Corbett-Detig et al. 2013. Genetic incompatibilities are widespread
within species. Nature.

2.       *Marcos Antezana:*

Valen, L. v. 1975. Energy and Evolution. University of Chicago, Department
of Biology.

3.       *Remco Folkertsma:*

1. The work by Hopi Hoekstra on local adaptation and oldfield mice

2. Poelstra, J. W., Vijay, N., Bossu, C. M., Lantz, H., Ryll, B., M&uuml;ller,
I., ... &amp; Wolf, J. B. (2014). The genomic landscape underlying phenotypic
integrity in the face of gene flow in crows. Science, 344(6190), 1410-1414.

4.       *Joshka Kaufmann and Leslie Turner*

They offer us a link to 'papers every evolutionary biologist should read',
the papers are collected by Leslie Turner.
https://static1.squarespace.com/static/53e8cb7ce4b02c4bc3aeeee4/t/5ab8fcb670a6ad55c67fcdf4/1522072758665/EvoBioClassicsRefList.pdf

5.       *Sarah Stockwell*

Matt Ridley collected classic papers in evolutionary biology and printed
part of these papers in his book Evolution (see Matt Ridley. Evolution
(Univ. of Oxford Press, 2nd edition, 2004))
</pre>]]></description>
	<dc:creator>BioStar</dc:creator>
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<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/6836/research-fellow-mendel-laboratory</guid>
  <pubDate>Tue, 26 Nov 2013 00:07:57 -0600</pubDate>
  <link></link>
  <title><![CDATA[Research Fellow @ Mendel laboratory]]></title>
  <description><![CDATA[
<p>IRCCS Casa Sollievo della Sofferenza – Mendel laboratory is seeking one talented bioinformatician (Rome)<br />Start date: immediate</p>

<p>Duration: 1 year</p>

<p>Funding Source: Institutional<br />Salary on grant: B2 (€ 22.000/year gross)<br />Contact Person (Referent): Tommaso Mazza<br />Ref. E-Mail: t.mazza@css-mendel.it<br />Tel: +39 06 44160526<br />Fax: +39 06 44160548</p>

<p>Job Description: The bioinformatics unit at IRCCS Casa Sollievo della Sofferenza - Mendel laboratory in Rome is looking for one young PhD bioinformatician with specific experience and/or interest in the analysis of transcriptomic data.</p>

<p>The candidate will be mainly in charge of developing research on a range of hot applications and projects, dealing with microarrays, RNA-Seq and miRNA-Seq data. Main activities will be: (i) data analysis (short-reads mapping, variants call and annotation, functional enrichment analysis of gene expression data); (ii) networks analysis and simulation (artificial knockout, redundancy and lethality analysis, gene set essentiality); (iii) developing of ad-hoc software solutions/routines on clusters of CPUs and GPUs.</p>

<p>The correct cultural background (training in Biology / Computer Science / Statistics or a mix of the three) and a strong interest in working with high throughput data analysis will be considered at the same level of specific experience in the above-mentioned fields.<br />Knowledge of molecular modeling and simulation and one of these languages: python, perl, R, Java, C++, C# is a golden plus. Good knowledge of Scientific English will be positively evaluated for this position, together with good presentation and teamwork skills.</p>

<p>A CV with one professional reference, details on educational background and of the biological and/or bioinformatic and/or data analysis skills and experience should be sent by email for a preliminary selection to: Tommaso Mazza, CSS-Mendel: t.mazza@css-mendel.it</p>

<p>Context<br />Casa Sollievo della Sofferenza is an Institute for hospitalization, care, and scientific research located in San Giovanni Rotondo, Italy. It integrates clinical assistance (with inpatient and outpatient facilities) and research. It has an affiliate institute, CSS-Mendel, located in Rome. Between the two sites, it employs over 100 researchers who focus on genetics. The Center is equipped with state of the art genomics technology (SOLiD 5500XL next generation sequencer, Illumina MiSeq, Affymetrix/Agilent microarray platforms, etc) as well as a dedicated high performance computing facility, a non-conventional workstation of GPUs and a short- and long-term storage disk.</p>

<p>Applications<br />Candidates should send:<br />• a cover letter explaining the role they would like to undertake within the Center, even if it is not listed in this job adv, stating clearly why they would be a good fit to the proposed role, and what they would bring to the Center in terms of expertise, ideas, talent;<br />• a CV including a list of publications;<br />• List of referees;</p>

<p>More at http://www.css-mendel.it/</p>
]]></description>
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