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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/29912?offset=380</link>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/27333/satsuma-highly-sensitive-whole-genome-synteny-alignments</guid>
	<pubDate>Fri, 13 May 2016 05:25:26 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/27333/satsuma-highly-sensitive-whole-genome-synteny-alignments</link>
	<title><![CDATA[SATSUMA : Highly sensitive whole-genome synteny alignments.]]></title>
	<description><![CDATA[<p>Satsuma is a whole-genome synteny alignment program. It takes two genomes, computes alignments, and then keeps only the parts that are orthologous, i.e. following the conserved order and orientation of features, such as protein coding genes, non-coding genes, or neutral sequences. Satsuma does not require any pre-processing, such as repeat masking, since it will automatically detect ambiguous mappings.<br> <br> Satsuma has parallelization built-in and is designed to run on multi-core architectures. The run-time for aligning two bird-size genomes (~1.2 Gb) is around two days on 24 CPUs. <br> <br> You can find the manual <a href="http://satsuma.sourceforge.net/manual.html">here</a>.<br> Download the latest source code from <a href="https://sourceforge.net/projects/satsuma/">here.</a><br> Stable versions can also be downloaded from the <a href="https://www.broadinstitute.org/science/programs/genome-biology/spines">Broad Institute's</a> web site.<br> <br> An incomplete list of questions and answers (yes, these have really been asked by our users! Please feel free to add your own by e-mailing us) is <a href="http://satsuma.sourceforge.net/faq.html">here</a>.<br> <br> If you use Satsuma in your research, please cite:<br> <a href="http://bioinformatics.oxfordjournals.org/content/26/9/1145.long">Grabherr, M. G., Russell, P., Meyer, M., Mauceli, E., Alf&ouml;ldi, J., Di Palma, F., &amp; Lindblad-Toh, K. (2010). Genome-wide synteny through highly sensitive sequence alignment: Satsuma. Bioinformatics, 26(9), 1145-51</a>.</p>
<p><strong>Tutorial at http://evomics.org/learning/genomics/satsuma/</strong></p><p>Address of the bookmark: <a href="http://satsuma.sourceforge.net/" rel="nofollow">http://satsuma.sourceforge.net/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/27479/biogps</guid>
	<pubDate>Mon, 23 May 2016 03:15:46 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/27479/biogps</link>
	<title><![CDATA[BioGPS]]></title>
	<description><![CDATA[<p>A free&nbsp;<em>extensible</em>&nbsp;and&nbsp;<em>customizable</em>&nbsp;<strong>gene annotation portal</strong>, a complete resource for learning about&nbsp;<strong>gene and protein function</strong>.</p>
<p>http://biogps.org/#goto=welcome</p><p>Address of the bookmark: <a href="http://biogps.org/#goto=welcome" rel="nofollow">http://biogps.org/#goto=welcome</a></p>]]></description>
	<dc:creator>Anjana</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/27679/cluego</guid>
	<pubDate>Thu, 02 Jun 2016 09:51:44 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/27679/cluego</link>
	<title><![CDATA[ClueGO]]></title>
	<description><![CDATA[<p>ClueGO is a Cytoscape plug-in that visualizes the non-redundant biological terms for large clusters of genes in a functionally grouped network and it can be used in combination with GOlorize.</p><p>Address of the bookmark: <a href="http://www.ici.upmc.fr/cluego/" rel="nofollow">http://www.ici.upmc.fr/cluego/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/27827/guest-faculty-centre-for-bioinformatics-at-pondicherry-university</guid>
  <pubDate>Wed, 15 Jun 2016 03:44:31 -0500</pubDate>
  <link></link>
  <title><![CDATA[Guest Faculty Centre for Bioinformatics at Pondicherry University]]></title>
  <description><![CDATA[
<p>Guest Faculty Centre For Bioinformatics Jobs opportunity in Pondicherry University<br />Qualification : M.Phil. (with NET/SLET)/ M.Tech. / M.E. in Computer Science with a minimum of 55% of marks as per UGC norms.<br />Desirable : Ph.D and Teaching experience in Perl and Java programming.<br />Honorarium : Rs. 1,000/- per lecture (subject to a maximum of Rs. 25,000/- per month)<br />How to apply<br />Walk-in-Interview will be held on 29.06.2016 (Wednesday) at 2:30 P.M at the office of Centre for Bioinformatics, Pondicherry University, Puducherry — 605 014. Interested eligible candidates may attend the Walk-in-Interview along with all original certificates, self attested photocopies and testimonials with a copy of their bio-data. Candidates reporting after 2:30 P.M will not be entertained.</p>

<p>More at http://www.pondiuni.edu.in/news?quicktabs_2=5#quicktabs-2</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/27959/darkhorse</guid>
	<pubDate>Wed, 22 Jun 2016 05:37:38 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/27959/darkhorse</link>
	<title><![CDATA[DarkHorse]]></title>
	<description><![CDATA[<p><em>DarkHorse</em>&nbsp;is a bioinformatic method for rapid, automated identification and ranking of phylogenetically atypical proteins on a genome-wide basis. It works by selecting potential ortholog matches from a reference database of amino acid sequences, then using these matches to calculate a lineage probability index (LPI) score for each genome protein.</p>
<p>LPI scores are inversely proportional to the phylogenetic distance between database match sequences and the query genome. These scores are useful not only for large-scale<em>de novo</em>&nbsp;predictions of horizontally transferred proteins, but can also serve as an independent quality control test for potential horizontal transfer candidates identified by alternative methods, especially those based on nucleic acid signatures. Candidates having high LPI scores are unlikely to have been horizontally transferred, since they are highly conserved among closely related organisms.</p>
<p>One unique and powerful feature of the DarkHorse HGT Candidate database is the opportunity to explore the phylogenetic background of potential HGT donors as well as recipients. The breadth of the database allows not only query sequences, but also their database match partners to be evaluated for sequence similarity or novelty compared to taxonomically related organisms.</p>
<p><em>DarkHorse</em>&nbsp;is configurable for varying degrees of phylogenetic granularity and protein sequence conservation. Users should consult the&nbsp;<a href="http://darkhorse.ucsd.edu/#references">references</a>&nbsp;cited below for a complete explanation of parameter selection and result interpretation. A brief&nbsp;<a href="http://darkhorse.ucsd.edu/tutorial.html">tutorial</a>&nbsp;page is also available on-line.</p><p>Address of the bookmark: <a href="http://darkhorse.ucsd.edu/download.html" rel="nofollow">http://darkhorse.ucsd.edu/download.html</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/27961/nearhgt</guid>
	<pubDate>Wed, 22 Jun 2016 05:41:57 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/27961/nearhgt</link>
	<title><![CDATA[NearHGT]]></title>
	<description><![CDATA[<p>Horizontal gene transfer (HGT), the transfer of genetic material between organisms, is crucial for genetic innovation and the evolution of genome architecture. Existing HGT detection algorithms rely on a strong phylogenetic signal distinguishing the transferred sequence from ancestral (vertically derived) genes in its recipient genome. Detecting HGT between closely related species or strains is challenging, as the phylogenetic signal is usually weak and the nucleotide composition is normally nearly identical. Nevertheless, there is a great importance in detecting HGT between congeneric species or strains, especially in clinical microbiology, where understanding the emergence of new virulent and drug-resistant strains is crucial, and often time-sensitive.</p>
<p>We developed a novel, self-contained technique named&nbsp;<em>Near HGT</em>, based on the&nbsp;<em>synteny index</em>, to measure the divergence of a gene from its native genomic environment and used it to identify candidate HGT events between closely related strains. The method confirms candidate transferred genes based on the&nbsp;<em>constant relative mutability</em>&nbsp;(CRM). Using CRM, the algorithm assigns a confidence score based on &ldquo;unusual&rdquo; sequence divergence. A gene exhibiting exceptional deviations according to both synteny and mutability criteria, is considered a validated HGT product. We first employed the technique to a set of three&nbsp;<em>E. coli</em>&nbsp;strains and detected several highly probable horizontally acquired genes. We then compared the method to existing HGT detection tools using a larger strain data set.</p>
<p>When combined with additional approaches our new algorithm provides richer picture and brings us closer to the goal of detecting all newly acquired genes in a particular strain.</p>
<p><strong>Availability:</strong><span>&nbsp;The method is publicly available at</span><a href="http://research.haifa.ac.il/~ssagi/software/nearHGT.zip">http://research.haifa.ac.il/~ssagi/software/nearHGT.zip</a></p><p>Address of the bookmark: <a href="http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1004408" rel="nofollow">http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1004408</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/28425/advertisement-for-junior-research-fellowjrf-at-school-of-computational-and-integrative-sciences-jawaharlal-nehru-university</guid>
  <pubDate>Thu, 14 Jul 2016 07:24:53 -0500</pubDate>
  <link></link>
  <title><![CDATA[Advertisement for Junior Research Fellow(JRF)  at School of Computational and Integrative Sciences  Jawaharlal Nehru University]]></title>
  <description><![CDATA[
<p>Advertisement for Junior Research Fellow(JRF) - (1)</p>

<p>Applications are invited for a post in DST, India funded Project entitled: "Positive and negative impacts of macromolecular crowding agents during target site location by DNA binding proteins – origin of optimal search at physiological ionic concentration (Reference Number: ECR/2016/000188) ''. The selected candidate will be appointed purely on temporary basis, initially for two years as a JRF that may be extended to one year of SRF based on the performance.</p>

<p>Position: Junior Research Fellow (1)</p>

<p>Qualifications &amp; Experience: Candidate must have a consistently good academic record with at least 60% marks in all throughout and must have qualified NET/GATE.</p>

<p>Desirable: Basic knowledge in the field of biophysics, molecular simulations and computational biology are desirable.</p>

<p>Salary: Consolidated Rs. 25,000 per month.</p>

<p>Tenure: The project duration is for three years and the selected candidate would be appointed after an interview. Appointment will be purely on temporary basis as stipulated by the existing rules of the University.</p>

<p>Interested candidates need to send an application to the address mentioned below mentioning the name of the project and post applied for (on the cover of the envelope).</p>

<p>The applications along with CV should be mailed at the address given below. Name, address, contact number and e. mail address of two referees must be enclosed with the application. The last date for the application is July 31st 2016.</p>

<p>Dr. Arnab Bhattacharjee (Principal Investigator) <br />Assistant Professor <br />School of Computational and Integrative Sciences <br />Jawaharlal Nehru University <br />New Delhi-110067 <br />E-mail: arnab@jnu.ac.in</p>

<p>Note: 1. Only shortlisted candidates will be communicated to appear in the interview at SCIS, JNU and no other communications in this regard will be entertained.</p>

<p>2. No TA/DA will be paid for appearing in interview.</p>
]]></description>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/28547/jrf-bioinformatics-at-iit-delhi</guid>
  <pubDate>Mon, 25 Jul 2016 03:26:20 -0500</pubDate>
  <link></link>
  <title><![CDATA[JRF Bioinformatics at IIT, Delhi]]></title>
  <description><![CDATA[
<p>No. IITD/IRD/RP03017/4254/Advertisement No.: IITD/IRD/093/2016<br />JRF Bioinformatics  job vacancies in Indian Institute of Technology Delhi (IIT Delhi)<br />Title : Elucidation of Pathologically Relevant miRNAs Responsible for Disease Progression and Resistance to Chemotherapy in Chronic Lymphocytic Leukemia (CLL) (RP03017)<br />Qualification : Candidates having first class B. Tech. / M.Sc. Degree or equivalent in Bioinformatics or Biotechnology with NET qualification. Desirable: Candidates having computer programming skills (C++, Python, Java, Web designing using Materialize frameworks, database management, offline software GUI development) with knowledge of Linux server environment and / or experience in next generation sequencing (NGS) data analysis, MD simulations will be preferred.<br />No. of Post : 01<br />Pay Scale : Rs.25,000/-<br />How to apply<br />Walk-in test / interview will be held on 04/08/2016, 03.00 p.m. at Committee Room No. 230, Block-I, Department of Biochemical Engineering &amp; Biotechnology, Indian Institute of Technology Delhi, Hauz Khas, New Delhi-110016.</p>

<p>More at http://ird.iitd.ac.in/sites/default/files/jobs/project/IITD-IRD-093-2016.pdf</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/28566/emboss-apps</guid>
	<pubDate>Wed, 27 Jul 2016 06:00:41 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/28566/emboss-apps</link>
	<title><![CDATA[EMBOSS Apps]]></title>
	<description><![CDATA[<p>The programs are listed in alphabetical order, Look at the individual applications or go to the&nbsp;<a href="http://emboss.sourceforge.net/apps/release/6.6/emboss/apps/groups.html">GROUPS</a>&nbsp;page to search by category.</p>
<p><a href="http://emboss.sourceforge.net/apps/release/6.6/embassy/index.html">EMBASSY applications</a>&nbsp;are described in separate documentation for each package.</p>
<h3><a name="current" id="current"></a>Applications&nbsp;in the&nbsp;<a href="ftp://emboss.open-bio.org/pub/EMBOSS/">current release</a></h3><p>Address of the bookmark: <a href="http://emboss.sourceforge.net/apps/release/6.6/emboss/apps/" rel="nofollow">http://emboss.sourceforge.net/apps/release/6.6/emboss/apps/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/28602/srf-and-jrf-bioinformatics-at-tezpur-university-napaam</guid>
  <pubDate>Wed, 03 Aug 2016 03:47:38 -0500</pubDate>
  <link></link>
  <title><![CDATA[SRF and JRF Bioinformatics at Tezpur University, Napaam]]></title>
  <description><![CDATA[
<p>Applications are invited for the following temporary positions unde MHRD sponsored Centre of Excellence<br />in the Department of Computer Science and Engineering (CSE), Tezpur University<br /> <br />Qualification<br />and Experience : Senior Research Fellow (SRF) and JRF : First Class in M.E/M.Tech in CSE/IT/ECE with research<br />experience in relevant fields of research (Candidates having valid GATE/NET Score would be preferred).</p>

<p> <br />Fellowship: Rs. 18,000/- per month (fixed)<br /> <br />Duration : 2 (Two) years and may be extended<br />depending on status of the project<br /> <br />Age Limit: Candidates should not be more than 32 years of<br />age in case of SRF and 28 years of age in case of JRF and TA. Upper age limit may be relaxed up to 5<br />years in the case of candidate belonging to SC/ ST/ OBC/ Women/ Differently abled.<br /> <br />How to Apply:<br />Interested candidates may send their application on plain paper by post along with his/her educational<br />qualifications, research experience certificates (for SRF), 02 copies of recent passport/stamp size photographs<br />and contact phone number to Professor D.K Bhattacharyya, Principal Investigator, Department of Computer<br />Science &amp; Engineering, Tezpur University, Napaam – 784 028, or mail it to dkb@tezu.ernet.in<br />(or to smh@tezu.ernet.in) within 15 days of publication of this advertisement.<br /> <br />No TA/DA shall<br />be paid for attending the interview.<br /> <br />For more details: http://www.tezu.ernet.in/ProjectWalkin/Advt-DoRD-CSE-DKB-20-225-6779-A.pdf</p>
]]></description>
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