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<channel>
	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/30085?offset=860</link>
	<atom:link href="https://bioinformaticsonline.com/related/30085?offset=860" rel="self" type="application/rss+xml" />
	<description><![CDATA[]]></description>
	
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	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/7568/oldest-hominin-dna-sequenced</guid>
	<pubDate>Fri, 27 Dec 2013 19:58:31 -0600</pubDate>
	<link>https://bioinformaticsonline.com/news/view/7568/oldest-hominin-dna-sequenced</link>
	<title><![CDATA[Oldest Hominin DNA Sequenced]]></title>
	<description><![CDATA[<p>Matthias Meyer and his team from the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany, have developed new techniques for retrieving and sequencing highly degraded ancient DNA. They then joined forces with Juan-Luis Arsuaga and applied the new techniques to a cave bear from the Sima de los Huesos site. After this success, the researchers sampled two grams of bone powder from a hominin thigh bone from the cave. They extracted its DNA and sequenced the genome of the mitochondria or mtDNA, a small part of the genome that is passed down along the maternal line and occurs in many copies per cell. The researchers then compared this ancient mitochondrial DNA with Neandertals, Denisovans, present-day humans, and apes.<br /><br />From the missing mutations in the old DNA sequences the researchers calculated that the Sima hominin lived about 400,000 years ago. They also found that it shared a common ancestor with the Denisovans, an extinct archaic group from Asia related to the Neandertals, about 700,000 years ago. "The fact that the mtDNA of the Sima de los Huesos hominin shares a common ancestor with Denisovan rather than Neandertal mtDNAs is unexpected since its skeletal remains carry Neandertal-derived features," says Matthias Meyer. Considering their age and Neandertal-like features, the Sima hominins were likely related to the population ancestral to both Neandertals and Denisovans. Another possibility is that gene flow from yet another group of hominins brought the Denisova-like mtDNA into the Sima hominins or their ancestors.<br /><br /></p><p>Reference</p><p>http://www.sciencedaily.com/releases/2013/12/131204132018.htm</p>]]></description>
	<dc:creator>Surajeet</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/41043/postdoctoral-scientist-genome-analytics-genome-bioinformatics-mf</guid>
  <pubDate>Sun, 16 Feb 2020 02:57:40 -0600</pubDate>
  <link></link>
  <title><![CDATA[Postdoctoral scientist genome analytics/ genome bioinformatics (m/f/*)]]></title>
  <description><![CDATA[
<p>https://www.uksh.de/jobs/Stellenangebote-nr-20190570-p-8.html<br />Your profile:<br />Degree in bioinformatics, biostatistics, or equivalent<br />Experience in the processing and analysis of large-scale genomics data using compute clusters / high-performance computing<br />Strong competence in working in Unix/Linux environments (shell)<br />Strong programming skills (in particular: Python, R, Perl)<br />Experience with using git and snakemake<br />Fluent English language skills, both spoken and written<br />Strong communication skills and motivation to work in a young, interdisciplinary, dynamic team</p>

<p>Additional Information:</p>

<p>If you have any questions about scientific aspects of this position, please contact Prof. Lars Bertram, head of LIGA (lars.bertram@uni-luebeck.de).</p>

<p>Please contact Ms. Anna Wolbert for further questions about administrative details (recruiting@uksh.de).</p>

<p>Weitere Informationen erhalten Sie auch unter www.uksh.de/karriere.</p>

<p>Wir freuen uns auf Ihre Bewerbung bis zum 15.03.2020 unter Angabe unserer Ausschreibungsnummer 20190570.119.CL.</p>
]]></description>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/7998/faculty-positions-at-iiit-allahabad</guid>
  <pubDate>Thu, 23 Jan 2014 06:19:34 -0600</pubDate>
  <link></link>
  <title><![CDATA[FACULTY POSITIONS AT IIIT-ALLAHABAD]]></title>
  <description><![CDATA[
<p>OPENINGS OF FACULTY POSITIONS AT IIIT-ALLAHABAD</p>

<p>(Under Tenure-Track Model)</p>

<p>Open Advt. No IIITA/DIC/16012014</p>

<p>IIIT-Allahabad has several Openings for the Faculty positions at the Assistant Professor level.</p>

<p>It is a regular tenure-track faculty positions for 3-5 years in teaching and research. A regular faculty is expected to engage heavily in research and teaching. The eligibility criteria for regular faculty positions are similar as in IITs. For an Assistant Professor position, a candidate must have a PhD (in IT/Computer Science &amp;/or Engineering/Electrical, Electronics &amp;/or Communication Engineering/etc; for interdisciplinary areas the PhD may be in an appropriate field), plus three years experience. However, for PhDs from a well known University/Institute (e.g. IITs/IISc/TIFR/ISI in India or well known research universities across the world), and a good research/academic record, the 3 years experience requirement may be waived.</p>

<p>The pay scale for faculty is same as in IITs. Other benefits include initiation research grant, travel support, book grant, professional society membership, etc., and personal benefits such as medical/LTC, on campus subsidized family housing with excellent modern infrastructural facilities.</p>

<p>Areas of Interest</p>

<p>IIIT-Allahabad aims to build strong research groups in important and emerging areas in CS/IT/ECE as well as in emerging interdisciplinary areas, and applications are invited in all these areas. Some of the areas of special interest, besides strengthening the existing research areas, are : Software Engineering, Theoretical Computer Science, Cyber Physical Systems, Robotics, Network science, Digital Media, Computational neuroscience, Machine learning, Healthcare informatics, Computational Biology, Communications networks (both at hardware and protocol levels), Circuits (including VLSI, analog, low power, etc), Energy systems and technologies, Biomedical electronics and systems, Computer Architecture, signal/image processing, Embedded and control systems.</p>

<p>Application Process</p>

<p>Interested candidates can apply by sending their detailed CV with list of publications clearly mentioning Journal names and citation index with three references through email entitled “Faculty positions at IIIT Allahabad” to faculty.applications@iiita.ac.in. Do not send your applications in any other email addresses. Applications will be considered regularly, hence there is no deadline for applying.</p>

<p>Important Clarifications on Eligibility</p>

<p>A PhD in CS/IT (or other disciplines, as announced) is the minimum expected requirement for an Assistant Professor.</p>

<p>Advertisement: http://iiita.ac.in/pub/Faculty-Position-IIITA1.pdf</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/42917/fings-filters-for-next-generation-sequencing</guid>
	<pubDate>Sat, 27 Feb 2021 01:18:35 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/42917/fings-filters-for-next-generation-sequencing</link>
	<title><![CDATA[FiNGS: Filters for Next Generation Sequencing]]></title>
	<description><![CDATA[<h2>Key features</h2>
<ul>
<li><strong>Filters SNVs from any variant caller to remove false positives</strong></li>
<li><strong>Calculates metrics based on BAM files and provides filtering not possible with other tools</strong></li>
<li><strong>Fully user-configurable filtering (including which filters to use and their thresholds)</strong></li>
<li><strong>Option to use filters identical to ICGC recommendations</strong></li>
</ul>
<p>FiNGS provides researchers with a tool to reproducibly filter somatic variants that is simple to both deploy and use, with filters and thresholds that are fully configurable by the user. It ingests and emits standard variant call format (VCF) files and will slot into existing sequencing pipelines. It allows users to develop and implement their own filtering strategies and simple sharing of these with others.</p>
<p>FiNGS reliably improves upon the precision of default variant caller outputs and performs better than other tools designed for the same task.</p><p>Address of the bookmark: <a href="https://github.com/cpwardell/FiNGS" rel="nofollow">https://github.com/cpwardell/FiNGS</a></p>]]></description>
	<dc:creator>Neel</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/11528/post-doctoral-research-assistant-in-genetics</guid>
  <pubDate>Thu, 05 Jun 2014 16:01:39 -0500</pubDate>
  <link></link>
  <title><![CDATA[Post-doctoral Research Assistant in Genetics]]></title>
  <description><![CDATA[
<p>Post-doctoral Research Assistant in Genetics<br />Camden, North London<br />£31.1K per annum inclusive of London Weighting</p>

<p>This is a fixed term post for 36 months.</p>

<p>We wish to recruit a highly motivated, postdoctoral scientist to carry out a BBSRC funded project in the laboratory of Dr. Denis Larkin. The project is focused on developing and applying new algorithms to study genome and chromosome evolution in birds, mammals and other vertebrate species using whole-genome sequences and existing algorithms. The post holder will use cutting edge computational and laboratory approaches to generate chromosomal assemblies for sequenced genomes, study chromosomal structures and genome differences between bird and other vertebrate species in attempt to identify species- and clade-specific genome signatures.</p>

<p>Applicants must have a Ph.D. and a track record of success, as indicated by first-author publications in international journals. They must possess excellent organisation skills and be capable of individual initiative and of interacting as part of a team. Applicants with extensive practical experience in bioinformatics or computer science, programming, visualization, handling of large data sets, high-performance computing are encouraged to apply. The post will involve collaboration with a wide range of academic partners both within the UK, EU and worldwide. In addition to leading their own project the post holder will have opportunities to contribute to multiple international genome initiatives.</p>

<p>Experience in programming, bioinformatics and comparative genome analysis is essential. Applicants should have a minimum of a degree and preferably a higher degree in a relevant subject.</p>

<p>The Royal Veterinary College has the largest range of veterinary, para-veterinary and animal science undergraduate and postgraduate courses of any veterinary school in the world and is one of the largest veterinary schools in Europe.</p>

<p>Prospective applicants are encouraged to contact Dr. Denis Larkin, Comparative Biomedical Sciences Department on +442071211906 or email: dlarkin@rvc.ac.uk</p>

<p>We offer a generous reward package.</p>

<p>For further information and to apply on-line please visit our website: www.rvc.ac.uk<br />Job reference CBS-0025-14A</p>

<p>Closing date: 4 July 2014<br />Interviews are likely to be held in July 2014</p>

<p>We promote equality of opportunity and diversity within the workplace and welcome applications from all sections of the community.</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/pages/view/44672/libraries-or-management-tools-for-high-throughput-sequencing-data</guid>
	<pubDate>Fri, 04 Oct 2024 02:45:06 -0500</pubDate>
	<link>https://bioinformaticsonline.com/pages/view/44672/libraries-or-management-tools-for-high-throughput-sequencing-data</link>
	<title><![CDATA[Libraries or management tools for high throughput sequencing data]]></title>
	<description><![CDATA[<ul>
<li><a href="http://gatb.inria.fr/"><span>GATB</span></a>&nbsp;Library.&nbsp;The&nbsp;<span>Genome Analysis Toolbox with de-Bruijn graph.&nbsp;</span>A large part of tools developed by the GenScale team are based on this library.<br />These methods enable the analysis of data sets of any size on multi-core desktop computers, including very huge amount of reads data coming from any kind of organisms such as bacteria, plants, animals and even complex samples (<em>e.g.</em>&nbsp;metagenomes). Among them are (the full is available here:&nbsp;<a href="https://gatb.inria.fr/software/">https://gatb.inria.fr/software/</a>):</li>
<li><a href="https://github.com/morispi/LRez"><span>LRez</span></a>: C++ Library and toolkit for the barcode-based management and indexation of linked-read datasets.</li>
</ul><h2>Variant calling and/or genotyping</h2><ul>
<li><a href="https://gatb.inria.fr/software/discosnp/" title="DiscoSNP">DiscoSNP++ and&nbsp;discoSnpRAD</a>: Reference-free small variant discovery (SNPs and indels)</li>
<li><a href="https://gatb.inria.fr/software/mind-the-gap/" title="MindTheGap">MindTheGap</a>: Detection and assembly of large insertion variants</li>
<li><a href="https://gatb.inria.fr/software/takeabreak/" title="TakeABreak">TakeABreak</a>:&nbsp;reference-free inversion discovery tool</li>
<li><a href="https://github.com/llecompte/SVJedi">SVJedi</a>: Structural Variant genotyper with long read data</li>
<li><a href="https://github.com/SandraLouise/SVJedi-graph">SVJedi-graph</a>: Structural Variant genotyper with long read data using a variation graph</li>
</ul><h2>Sequence assembly</h2><ul>
<li><a href="https://github.com/cguyomar/MinYS">MinYS</a>: reference-guided genome assembly in metagenomics data</li>
<li><a href="https://github.com/anne-gcd/MTG-Link">MTG-link</a>: local assembly tool for linked-read data</li>
<li><a href="https://gatb.inria.fr/software/minia/" title="Minia">Minia</a>: De novo short read assembler</li>
<li><a href="https://gatb.inria.fr/de-novo-genome-assembly/">de-novo pipeline</a>:&nbsp;<em>de-novo</em>&nbsp;assembly pipeline (error correction / contigs / scaffolding) for genomes and meta-genomes</li>
<li><a href="https://gatb.inria.fr/software/mapsembler/" title="Mapsembler2">Mapsembler2</a>: Targeted assembly (not maintained)</li>
</ul><h2>Managing k-mers &amp; indexation</h2><ul>
<li><a href="https://github.com/lrobidou/findere">findere</a>:&nbsp;simple strategy for speeding up queries and for reducing false positive calls from any Approximate Membership Query data structure.
<ul>
<li><a href="https://github.com/lrobidou/fimpera">fimpera</a>&nbsp;extends findere adding the abundance information.</li>
</ul>
</li>
<li><a href="https://github.com/tlemane/kmtricks">kmtricks</a>:&nbsp;modular tool suite for counting kmers, and constructing Bloom filters or kmer matrices, for large collections of sequencing data.</li>
<li><a href="https://github.com/tlemane/kmindex">kmindex&nbsp;</a>is a tool for indexing and querying sequencing samples. It is built on top of kmtricks.</li>
<li><a href="https://github.com/pierrepeterlongo/back_to_sequences">back to sequences</a>: Find sequences (reads, unitigs, genes) related to a set of kmers in large datasets, in a matter of seconds.</li>
<li><a href="https://github.com/vicLeva/bqf">Backpack Quotient Filter</a>:&nbsp;k-mer indexing data structure with abundance</li>
<li><a href="http://github.com/GATB/rconnector">short read connector</a>:&nbsp;Detect similar reads from potentially large read set</li>
<li><a href="https://gatb.inria.fr/software/dsk/" title="DSK">DSK</a>:&nbsp;Count K-mer in sequences</li>
</ul><h2>Pangenome graph manipulation</h2><ul>
<li><a href="https://github.com/Tharos-ux/pancat">Pancat</a>: Pangenome Comparison and Analysis Toolkit</li>
<li><a href="https://pypi.org/project/gfagraphs/">GFAGraphs</a>: a Python library to handle pangenome graph files in GFA format.</li>
</ul><h2>Comparative metagenomics with k-mers</h2><ul>
<li><a href="https://github.com/GATB/simka">Simka and SimkaMin</a>:&nbsp;Comparative metagenomics for large-scale datasets</li>
<li><a href="https://team.inria.fr/genscale/high-throughput-sequence-analysis/compreads-metagenomic-data-analysis/">Comparead &amp; Commet</a>:&nbsp;comparison of metagenomic datasets</li>
</ul><h2>Species and bacterial strains identification</h2><ul>
<li><a href="https://github.com/gsiekaniec/ORI">ORI</a>: software using long nanopore reads to identify bacteria present in a sample at the strain level</li>
<li><a href="https://github.com/kevsilva/StrainFLAIR">StrainFLAIR</a>:&nbsp;STRAIN-level proFiLing using vArIation gRaph</li>
</ul><h2>General-purpose sequencing data manipulation</h2><ul>
<li><a href="https://team.inria.fr/genscale/ngs-software/gassst/">GASSST</a>:&nbsp;long read mapper</li>
<li><a href="https://gatb.inria.fr/software/leon/" title="Leon">Leon</a>: short read compressor (now included in GATB-core)</li>
<li><a href="https://gatb.inria.fr/software/bloocoo/" title="Bloocoo">Bloocoo</a>:&nbsp;short read corrector</li>
<li><a href="https://github.com/GATB/bcalm">BCALM</a>:&nbsp;Construct compacted de Bruijn graphs (unitigs)</li>
</ul><h2>&nbsp;Protein Structure</h2><ul>
<li><a href="https://team.inria.fr/genscale/protein-structure/a-purva-contact-map-overlap-solver/">A_Purva</a>:&nbsp;Contact Map Overlap solver</li>
<li><a href="https://team.inria.fr/genscale/protein-structure/md-jeep-distance-geomtry-solver/">MD-Jeep</a>:&nbsp;Distance Geometry solver</li>
<li><a href="https://team.inria.fr/genscale/csa-comparative-structural-alignment/">CSA</a>:&nbsp;Comparative Structural Alignment</li>
</ul><h2>Workflow</h2><ul>
<li><a href="https://team.inria.fr/genscale/workflows/slicee/">SLICEE</a>:&nbsp;parallel execution of bioinformatics workflows</li>
</ul><h3>Comparative Genomics</h3><ul>
<li><a href="https://team.inria.fr/genscale/comparative-genomics/cassis/">CASSIS</a>:&nbsp;detection of rearrangement breakpoints</li>
<li><a href="https://team.inria.fr/genscale/high-throughput-sequence-analysis/plast-intensive-sequence-comparison/">PLAST</a>:&nbsp;intensive bank-to-bank sequence comparison</li>
<li><a href="https://github.com/stephanierobin/DrjBreakpointFinder">DRJBreakpointFinder</a>: detection and precise localization of excision sites in proviral segments</li>
</ul>]]></description>
	<dc:creator>LEGE</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/8198/scientist-positions-at-rajiv-gandhi-centre-for-biotechnology</guid>
  <pubDate>Thu, 06 Feb 2014 23:18:49 -0600</pubDate>
  <link></link>
  <title><![CDATA[Scientist Positions at Rajiv Gandhi Centre for Biotechnology]]></title>
  <description><![CDATA[
<p>Rajiv Gandhi Centre for Biotechnology</p>

<p>An Autonomous National Institute under Government of India,<br />Ministry of Science &amp; Technology<br />Department of Biotechnology</p>

<p>No: RGCB/ Advt./2014/1   <br />January 24, 2014</p>

<p>Scientist Positions</p>

<p>Group Leader in Computational Biology/Bioinformatics<br />A highly motivated and innovative individual who will pursue basic research, solve biological problems with emphasis on computational and quantitative experimental methods and build active bridges to translational research. The scientist will also provide computational biology support to analyze complex data sets generated by RGCB scientists and collaborators.</p>

<p>Location: Thiruvananthapuram (Trivandrum)</p>

<p>The above positions will be at the E-II, F or equivalent levels. For senior applicants with an outstanding track record, an option of a contract career path for research excellence at Scientist G or H equivalent level can also be discussed. All positions will initially be for 5 years. Essential and desired qualifications as well as other relevant details for all the above positions are posted on the RGCB website (http://www.rgcb.res.in). The last date for receiving applications is March 14, 2014.   </p>

<p>Sd/-<br />Director</p>

<p>Rajiv Gandhi Centre for Biotechnology<br />Thycaud, P.O., Poojappura,<br />Thiruvananthapuram, Kerala, India-695 014<br />Ph.: 91-471-2529400 (30 Lines), 2347975, 2348104, 2348753, 2345899<br />Fax: 91-471-2348096, 2346333</p>

<p>More at http://rgcb.res.in/jobs.html</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/42972/list-of-bioinformatics-workflow-management-tools</guid>
	<pubDate>Sat, 20 Mar 2021 00:15:25 -0500</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/42972/list-of-bioinformatics-workflow-management-tools</link>
	<title><![CDATA[List of bioinformatics workflow management tools !]]></title>
	<description><![CDATA[<h3>Here are list of&nbsp;Workflow Managers</h3><ul>
<li><span><a href="https://github.com/pcingola/BigDataScript">BigDataScript</a></span>&nbsp;&ndash; A cross-system scripting language for working with big data pipelines in computer systems of different sizes and capabilities. [&nbsp;<a href="https://pubmed.ncbi.nlm.nih.gov/25189778">paper-2014</a>&nbsp;|&nbsp;<a href="https://pcingola.github.io/BigDataScript">web</a>&nbsp;]</li>
<li><span><a href="https://github.com/ssadedin/bpipe">Bpipe</a></span>&nbsp;&ndash; A small language for defining pipeline stages and linking them together to make pipelines. [&nbsp;<a href="http://docs.bpipe.org/">web</a>&nbsp;]</li>
<li><span><a href="https://github.com/common-workflow-language/common-workflow-language">Common Workflow Language</a></span>&nbsp;&ndash; a specification for describing analysis workflows and tools that are portable and scalable across a variety of software and hardware environments, from workstations to cluster, cloud, and high performance computing (HPC) environments. [&nbsp;<a href="http://www.commonwl.org/">web</a>&nbsp;]</li>
<li><span><a href="https://github.com/broadinstitute/cromwell">Cromwell</a></span>&nbsp;&ndash; A Workflow Management System geared towards scientific workflows. [&nbsp;<a href="https://cromwell.readthedocs.io/">web</a>&nbsp;]</li>
<li><span><a href="https://github.com/galaxyproject">Galaxy</a></span>&nbsp;&ndash; a popular open-source, web-based platform for data intensive biomedical research. Has several features, from data analysis to workflow management to visualization tools. [&nbsp;<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030816">paper-2018</a>&nbsp;|&nbsp;<a href="https://galaxyproject.org/">web</a>&nbsp;]</li>
<li><span><a href="https://github.com/nextflow-io/nextflow">Nextflow</a>&nbsp;(recommended)</span>&nbsp;&ndash; A fluent DSL modelled around the UNIX pipe concept, that simplifies writing parallel and scalable pipelines in a portable manner. [&nbsp;<a href="https://pubmed.ncbi.nlm.nih.gov/29412134">paper-2018</a>&nbsp;|&nbsp;<a href="http://nextflow.io/">web</a>&nbsp;]</li>
<li><span><a href="https://github.com/cgat-developers/ruffus">Ruffus</a></span>&nbsp;&ndash; Computation Pipeline library for python widely used in science and bioinformatics. [&nbsp;<a href="https://pubmed.ncbi.nlm.nih.gov/20847218">paper-2010</a>&nbsp;|&nbsp;<a href="http://www.ruffus.org.uk/">web</a>&nbsp;]</li>
<li><span><a href="https://github.com/SeqWare/seqware">SeqWare</a></span>&nbsp;&ndash; Hadoop Oozie-based workflow system focused on genomics data analysis in cloud environments. [&nbsp;<a href="https://pubmed.ncbi.nlm.nih.gov/21210981">paper-2010</a>&nbsp;|&nbsp;<a href="https://seqware.github.io/">web</a>&nbsp;]</li>
<li><span><a href="https://bitbucket.org/snakemake">Snakemake</a></span>&nbsp;&ndash; A workflow management system in Python that aims to reduce the complexity of creating workflows by providing a fast and comfortable execution environment. [&nbsp;<a href="https://pubmed.ncbi.nlm.nih.gov/29788404">paper-2018</a>&nbsp;|&nbsp;<a href="https://snakemake.readthedocs.io/">web</a>&nbsp;]</li>
<li><span><a href="https://github.com/broadinstitute/wdl">Workflow Descriptor Language</a></span>&nbsp;&ndash; Workflow standard developed by the Broad. [&nbsp;<a href="https://software.broadinstitute.org/wdl">web</a>&nbsp;]</li>
</ul>]]></description>
	<dc:creator>Rahul Nayak</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/8382/c-dac-launch-supercomputing-facility-param-bio-blaze</guid>
	<pubDate>Tue, 18 Feb 2014 11:55:14 -0600</pubDate>
	<link>https://bioinformaticsonline.com/news/view/8382/c-dac-launch-supercomputing-facility-param-bio-blaze</link>
	<title><![CDATA[C-DAC launch supercomputing facility "Param Bio Blaze" !!!]]></title>
	<description><![CDATA[<p>The bioinformatics centre at Centre for Development of Advanced Computing (C-DAC) completed 10 years, this month. Established in 2004, the centre has been widely used by numerous researchers across the globe and has an ultimate aim of making personalised drugs depending on the composition of a human body.<br /><br />When biological data is processed using computer science, statistics, mathematics and engineering, it constitutes bioinformatics. The technological advancements are bringing new dimensions to the understanding of molecular basis of living organisms. There is immense data generated due to computing, but storage and analysis of this data is becoming a challenge, therefore there is an urgent need of supercomputers.</p><p>The&nbsp;C-DAC will launch Param Bio Blaze, a supercomputing facility, to address the challenges in bioinformatics on Tuesday at a three-day symposium, titled: 'Accelerating biology: Computing life'. The supercomputing facility will be inaugurated on Tuesday by Ramakrishna Ramaswamy, vice-chancellor, Central University of Hyderabad at the Yashada. The new C-DAC's facility will have a capacity of 10 teraflop and will be able to analyse human cells and its functions.</p><p><img src="http://www.datacenterjournal.com/wp-content/uploads/2012/06/supercomputer.jpg" alt="image" width="1024" height="632" style="border: 0px; border: 0px;"></p><p><br />Param Bio Blaze will help have a larger storage space and better computing facility for the bioinformatics sector. The facility will help capture the movement of molecules and also interaction between two molecules and the effects.<br /><br />Applications of Param BioBlaze<br /><br />- Collaboration with National Centre for Cell Science for research on Malaria and understanding how the disease spreads<br /><br />- Collaborative work with Tata Memorial hospital on breast cancer and find out the difference between normal tissues and tissues from breast cancer patients<br /><br />- Designing anti-cancer molecules, a collaborative research with the University of Pune</p><p>Reference:</p><p>Times of India</p><p>Image:datacenterjournal.com</p>]]></description>
	<dc:creator>Rahul Nayak</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/37674/qualimap2-evaluating-next-generation-sequencing-alignment-data</guid>
	<pubDate>Tue, 11 Sep 2018 04:44:29 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/37674/qualimap2-evaluating-next-generation-sequencing-alignment-data</link>
	<title><![CDATA[Qualimap2: Evaluating next generation sequencing alignment data]]></title>
	<description><![CDATA[<p><strong>Qualimap 2</strong><span>&nbsp;is a platform-independent application written in Java and R that provides both a Graphical User Inteface (GUI) and a command-line interface to facilitate the quality control of alignment sequencing data and its derivatives like feature counts.&nbsp;</span><br><br><span>Supported types of experiments include:</span></p>
<ul>
<li>Whole-genome sequencing</li>
<li>Whole-exome sequencing</li>
<li>RNA-seq (speical mode available)</li>
<li>ChIP-seq</li>
</ul><p>Address of the bookmark: <a href="http://qualimap.bioinfo.cipf.es/" rel="nofollow">http://qualimap.bioinfo.cipf.es/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>

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