BOL: Related items

Live Webinar on RNA-Seq Data Analysis on 9 Nov 2016

Strand — Wed, 19 Oct 2016 05:25:27 -0500

Live Webinar on RNA-Seq Data Analysis

Abstract: Strand NGS supports an extensive workflow for the analysis and visualization of RNA-Seq data. The workflow includes Transcriptome / Genome alignment, Differential expression analysis with Statistical approach and Splicing events detection. Strand NGS also supports novel discovery like identification of novel genes, exons and Novel splice junctions, alongside it can also detect gene fusion events. Further downstream analysis such as GO and pathway analysis can be performed on the set of interesting genes. The product has an option to create pipelines for time consuming jobs which automates analysis and leaves more time for end data interpretation. This webinar will give an overview of the features in the RNA-Seq data analysis workflow in Strand NGS and also highlights on parameters within each feature that can be optimized depending on datasets and analysis needs.

Speaker: Mr. Sugandan Sivamani, Senior Application Scientist, Strand Life Sciences

Date: 9th Nov, Session 1 for SAPK/ APFO: 2:30 PM IST Date: 9th Nov, Session 2 for AFO/ EMEA: 9:00 AM PST

ICGEB Bioinformatics Research Associate Vacancy

Thu, 25 Jun 2015 20:41:00 -0500

Research Associate Position at ICGEB, New Delhi with Dr. Amit Sharma

Starting 15th July 2015, the position relates to a project specifically for in silico drug docking, screening, design, optimisation and linkage with active chemists.

Experience in many docking softwares and operating systems is essential.

Additional experience in bioinformatics and computational biology tools will be useful.

Submit curriculum vitae to: sb.icgeb@gmail.com

Closing date: 5 July 2015

Quick next generation sequencing (NGS) terms definition

Neel — Fri, 09 Jun 2017 04:52:26 -0500

fragment size: the Illumina WGS protocol generates paired-end reads from both ends of longer fragments. The lengths of these fragments are assumed to be sampled from a normal distribution. Therefore, in the absence of structural variants, mapping locations of the paired ends span within an interval [δmin,δmax]. Most (>90%) of paired-end reads are sampled from no-SV regions, therefore the fragment size distribution can be learned empirically for each WGS data set separately.

concordant reads: a read pair is called concordant if they can be mapped to the reference genome as “expected”: (a) mapped to opposing strands where the upstream read is mapped to the forward strand and the downstream read is mapped to the reverse strand2, (b) the distance between ends is between the minimum and maximum expected fragment size.

discordant reads: briefly, any non-concordant read pair is considered discordant. Note that, by definition, the discordant read pairs signal potential SVs. The sequence signature produced by these type of reads is known as read-pair signature.

split reads: a read that can only be mapped to the reference genome by breaking into two sub-reads is called a split-read. These types of reads also indicate a potential SV or a short insertion or deletion (indel).

read depth: number of reads that map within a region of the genome. Overall genome-wide read depth is also referred to as depth of coverage. It is expected that the number of reads that “cover” each base-pair to follow a Poisson distribution. Therefore, if the read depth over a certain region deviates significantly from this distribution, it signals for a potential copy number variation (CNV).

Research Scientist at DuPONT

Fri, 17 Jul 2015 20:36:17 -0500

Research Scientist
Hyderabad, Telangana
Job Description

Job Description

The Global Trait Discovery Informatics (GTDI) group located at the DuPont Knowledge Centre (DKC), Hyderabad, India is currently seeking applications for a highly motivated computational biologist. The GTDI group contributes to research programs in plant biotechnology at the DKC as well as across research centers located in DuPont Pioneer, Johnston, Iowa and at the DuPont Experimental Station in Wilmington, Delaware.

We are looking for candidates who have experience in analysis of high-throughput -omics datasets. The researcher will be primarily responsible for analyzing diverse -omics datatypes, such as transcriptomics, proteomics and metabolomics and actively contribute towards building streamlined solutions.

The candidate will be part of a diverse team of experimental biologists, computational biologists and software developers. A critical aspect of this position involves working with global teams across multiple locations and will require effective project coordination and communication skills. This is an exciting opportunity for candidates with strong data driven skills, who want to work at the interface of computational and experimental biology and contribute towards scientific discovery.

Responsibilities

·Integrate and analyze multiple datatypes in the context of experimental observations with a goal towards formulating testable hypothesis.

·Understanding the research questions from experimental biologists and formulate relevant in silico analyses.

·Establish and implement systematic analysis workflows starting from processing of raw data to biological interpretation.

·Critically analyze a wide variety of experimental data with a view to solving the underlying research questions.

·Identify and generate datasets for scientific testing and evaluation of algorithms.

Qualifications

PhD in computational biology, bioinformatics, population genetics, complex systems, computer sciences or any relevant physical or mathematical sciences, with experience in analyzing diverse -omics datasets.

Job Qualifications

Qualifications

More at http://careers.dupont.com/jobsearch/job-details/research-scientist/006077W-01/

MIX: Combining multiple assemblies from NGS data

Rahul Nayak — Tue, 08 May 2018 04:58:05 -0500

Mix is a tool that combines two or more draft assemblies, without relying on a reference genome and has the goal to reduce contig fragmentation and thus speed-up genome finishing. The proposed algorithm builds an extension graph where vertices represent extremities of contigs and edges represent existing alignments between these extremities. These alignment edges are used for contig extension. The resulting output assembly corresponds to a path in the extension graph that maximizes the cumulative contig length.

The Mix algorithm, approach and results were published in BMC bioinformatics : http://www.biomedcentral.com/1471-2105/14/S15/S16.

Address of the bookmark: https://github.com/cbib/MIX

RA at CSIR-URDIP

Fri, 10 Jul 2015 18:34:03 -0500

CSIR - UNIT FOR RESEARCH AND DEVELOPMENT OF INFORMATION PRODUCTS (CSIR- URDIP)

Adv. No. URDIP/ 15/2015

Opportunity for young Bioinformatics Professionals to make a career in the area of Intellectual Property

CSIR has set up a Unit for Research and Development of Information Products (CSIRURDIP) at Pune to work in the area of scientific informatics. One of the major focus areas of research work at CSIR-URDIP is PATENT INFORMATICS. With the increasing applications of Bioinformatics in the areas of life sciences industry such as Agriculture and Health Care (Diagnostics and Drugs), the output of research in these area is being protected by different forms of Intellectual Property rights. Realizing the importance of IP in the Bioinformatics field, Department of Biotechnology (DBT) has sanctioned a project on “Development, Facilitation and Harvesting of Bioinformatics related Intellectual Property” at CSIR-URDIP.

The project will involve application of Patent Informatics tools and techniques to Bioinformatics (including creation of patent landscapes, preparation of techno-legal reports of patentability, freedom to operate studies) to help protect IPRs and develop and conduct training programmes on IPRs related to Bioinformatics.

CSIR-URDIP invites applications from young Bioinformatics professionals to work on this emerging area which offers challenging opportunities and attractive career possibilities in future.

Position I: Research Associate

No of Positions: One

Consolidated amount Payable: = Rs 26,400.00

Qualification: PhD in Bioinformatics. In exceptional cases, candidature of M. Tech. candidates with First class in Bioinformatics with three years of relevant work experience will also be considered.

Job requirement: The prospective candidate will be expected to identify patents/scientific literature in field of Bioinformatics, evaluate them Vis a Vis other patents in fields and come up landscape / FTO / Patentability reports.

Age Limit: 35 years.

The candidates meeting the above criteria may appear for walk in interview at their cost on Monday 13th July 2015 at 02:00 p.m. with the CV and supporting documents (original plus copies) at the following address: CSIR Unit or Research and Development of Information Products (URDIP), "Tapovan" S.No. 113 & 114, Near NCL Colony Baner Side Gate, NCL Estate, Pashan Road, Pune-411008, Maharashtra, India

Advertisement: www.urdip.res.in/download/DBT_RA_Advt_July%202015.pdf

HALC: High throughput algorithm for long read error correction

Jit — Fri, 08 Jun 2018 10:47:41 -0500

HALC, a high throughput algorithm for long read error correction. HALC aligns the long reads to short read contigs from the same species with a relatively low identity requirement so that a long read region can be aligned to at least one contig region, including its true genome region’s repeats in the contigs sufficiently similar to it (similar repeat based alignment approach) HALC was able to obtain 6.7-41.1% higher throughput than the existing algorithms while maintaining comparable accuracy. The HALC corrected long reads can thus result in 11.4-60.7% longer assembled contigs than the existing algorithms.

Address of the bookmark: https://github.com/lanl001/halc

Project Fellow at IHBT - Palampur, Himachal Pradesh

Sun, 12 Jul 2015 07:54:37 -0500

The Institute is working relentlessly on developing technologies for sustainable utilization of Himalayan bioresources, and in the area of tea, floriculture, bamboos and medicinal and aromatic plants. Looking at the mission of the Institute,the quantum of work undertaken and milestones achieved it was rightly conceived to rename the Institute from CSIR Complex Palampur to Institute of Himalayan Bioresource Technology at a high level meeting. Finally the Institute received its new name Institute of Himalayan Bioresource Technology (IHBT) in 1997 by then Prime Minister Shri H.D. Deve Gowda. Till date this is the only kind of National R&D laboratory in the state of Himachal.

Detail Of Institute of Himalayan Bioresource Technology (IHBT) Project Fellow Recruitment:

No.of Posts: 02

Qualification : 1st Class B. Tech. in Bioinformatics/ Computational Biology Or M.Sc. in Bioinformatics/ Computational Biology with 55% marks OR M.Tech. in Bioinformatics/ Computational Biology with 55% marks.

Age : 28 years as on 10.06.2015

Pay Scale: Rs.12,000/- P.M/Rs.14,000/- P.M.

Age : 35 years,(Up to 40 years for members of SC/STs).

Selection Procedure For Institute of Himalayan Bioresource Technology (IHBT) – Project Fellow Post:

Written Test on 10/06/2015.

Shortlisted candidates will undertake face to face interview.

Dates are yet to be announced for the final selection

Walkin Procedure For Project Fellow vacancy in Institute of Himalayan Bioresource Technology (IHBT):

Eligible candidates may appear for Walk-in-Interview on Date : 10.06.2015, Time 9:00 A.M. Venue : CSIR- IHBT Palampur (H.P.) alongwith an application on prescribed format. Candidates must also bring with them original certificates of testimonials at the time of the appearing for interview failing which he/she will not be allowed to appear for interview.

Important Dates To Remember :
Walk in date for this job : 10/06/2015

Convert EnsEMBL GTF to Annotation table (Geneid, GeneSymbol, GeneWiseChrLocation, GeneClass, Strand) Raw

EagleEye — Fri, 24 Jun 2016 18:08:49 -0500

Bash Script source:

https://gist.github.com/santhilalsubhash/367befcf5216be4b1fd9

Information:

This script converts EnsEMBL GTF (Ex: https://gist.githubusercontent.com/santhilalsubhash/1e7cca357e52a181dc25/raw/cfb803e07900a2baefbb6534f1299fd30cb57a29/sample.GTF) file to annotation table format. It generated two files
1) Transcript wise chromosome location with information about transcripts (Ex: https://gist.githubusercontent.com/santhilalsubhash/c7dec516e0338503a4b6/raw/de0af1a39f0005c4ce7321c5ae57fc8b4a14c7f4/sample.GTF_enst_annotation.txt)
2) Gene wise chromosome location with information about genes (Ex: https://gist.githubusercontent.com/santhilalsubhash/c92006c5080f0333bec2/raw/d16e0b2440d73b09b486d3c9751cdb248a73fa0b/sample.GTF_ensg_annotation.txt)

Note: You can download GTF files from http://www.ensembl.org/info/data/ftp/index.html

Assistant Professor/ Professor at Central University of South Bihar

Thu, 16 Jul 2015 22:36:53 -0500

Central University of South Bihar

(Established under Central Universities Act, 2009)

BIT Campus, PO: B.V. College,

Patna – 800 014 (Bihar)

Employment Notice No. CUSB / 27 / Faculty / 2015

Appointment for Faculty Positions Applications in the prescribed form are invited from the eligible candidates for the following posts shown against the subjects to be filled up on regular/contract/re-employment after superannuation basis:

1 Bioinformatics - 03 Posts

2 Biotechnology – 02 Posts

12 Life Science – 04 Posts

The duly filled in application form, complete in all respect along with fee must be sent only by Speed post/Registered post/Courier to The Registrar, Central University of South Bihar, BIT Campus, P.O. : B.V. College, Patna-800014.

Last Date of Receiving Application 10th August, 2015

http://cub.ac.in/index.php?option=com_content&view=article&id=31&Itemid=157