BOL: Related items

Chekulaevalab

Tue, 12 Jan 2016 02:32:03 -0600

Focusing on understanding the molecular mechanisms that regulate mRNA translation, localization and stability and role of non-coding RNAs in this process. Up to 90% of human DNA is estimated to be transcribed into so called non-coding RNAs that are not translated into proteins. Many of them act as potent modifiers of gene expression. miRNAs are a class of such short non-coding RNAs. They regulate expression of more than a half of eukaryotic genes, thus, affecting multiple biological processes, including cell proliferation, differentiation, apoptosis and senescence. Not surprisingly, miRNAs are involved in many human pathologies, including cancer and neurological disorders and hold great potential as drug targets, disease markers, as well as therapeutic agents.
Our lab is located at the Berlin Institute for Medical Systems Biology (BIMSB), a part of the Max Delbrück Center for Molecular Medicine (MDC).

http://www.chekulaevalab.org/

RA at University of Pune

Mon, 07 Mar 2016 03:48:33 -0600

Research Associate Job vacancies in University of Pune on temporary basis

No. of Post : 01

Department : Science and Technology

Qualifications : Ph.D. with specialization in Bioinformatics/Machine Learning/ Mathematical Biology/ Computational Biology/ Systems Biology with a minimum of 55% marks in M. Sc. (50% for candidates belongs to reserved category) or equivalent grade. Candidates who have submitted their Ph.D. thesis and are waiting for award of Ph.D. are also eligible. OR M. Sc. Bioinformatics with two years of research experience in the areas mentioned above, a minimum of 55% marks in M.Sc. (50% for candidates belongs to reserved categories) or equivalent grade and at least one publication in Science Citation Index (SCI) journal. Preference will be given to B.I.N.C. /J.R.F. /N.E.T. /S.E.T. qualified candidates.

Emoluments : Rs. 20,000/- (Including H.R.A.) per month.
How to apply

The complete application along with necessary documents and certificates should reach to 'The Director, Bioinformatics Centre, Savitribai Phule Pune University (Formerly University of Pune), Caneshkhind Road. Pune - 411 007 on or before 21st March, 2016 within official hours except Sundays (i.e. 10.20 am to 06.00 pm).

More at http://collegecirculars.unipune.ac.in/sites/documents/Job%20Openings/Forms/AllItems.aspx

Project Fellow Bioinformatics at Central University of Himachal Pradesh

Tue, 09 Feb 2016 03:58:00 -0600

Project Fellow Bioinformatics

Eligibility : MSc(Bio-Chemistry, Bio-Informatics)

Location : Kulu

Last Date : 07 Mar 2016

Hiring Process : Face to Face Interview
Central University of Himachal Pradesh

Project Fellow Bioinformatics Job in Central University of Himachal Pradesh

Project (MRP) entitled: “A project proposal on targeting novel prokaryotic ubiquitin like post-translational modification pathway for therapeutic interventions against Mycobacterium tuberculosis” (No. MRP-MAJOR-MICR-2013-26840)

Essential Qualification: 1. Master degree in Bioinformatics/Biochemistry/Biotechnology/Environmental Science/Microbiology or any branch of Life Sciences with a minimum of 55% marks for general category (50% in case of SC/ST/PH) 2. UGC/CSIR NET, GATE qualified candidates will be given preference. Desirable Qualification: Experience in basic Bioinformatics and Molecular Biology techniques.

Age: Below 40 years as on 01/10/2015.

No.of Post: 1

Salary: NET/GATE qualified candidate: Rs. 16,000/-p.m. for initial two years and Rs. 18,000/- p.m. for the third year. Non-NET/GATE candidates: Rs. 14,000/-p.m. for initial two years and Rs. 16,000/-p.m. for the third year.

Mode of Selection: The selection shall be made on the basis of merit. The eligible candidates are required to appear for interview before the duly constituted Selection Committee for the purpose. The scheduled date, time and venue for the interview shall be intimated to the eligible candidates through phone/ e-mail.
How to apply

Last date for the receipt of applications is 07.03.2016.

More at http://www.cuhimachal.ac.in/news_all.aspx

Centurion

Jit — Fri, 12 Feb 2016 04:45:41 -0600

Although centromeres are essential for life and are the subject of extensive research, centromere locations in yeast genomes are difficult to infer, and in most species they are still unknown. Recently, the chromatin conformation assay Hi-C has been re-purposed for diverse applications, including de novo genome assembly, deconvolution of metagenomic samples, and inference of centromere locations. We describe a method, Centurion, that jointly infers the locations of all centromeres in a single yeast genome by exploiting the centromeres’ tendency to cluster in 3D space. We first demonstrate the accuracy of Centurion in identifying known centromere locations from high coverage Hi-C data of budding yeast and a human malaria parasite. We then use two metagenomic samples with relatively low coverage Hi-C data to infer centromere locations for each chromosome in 14 different yeast species. For yeasts with large centromeres (e.g., S. pombe) Centurion predicts the exact centromere locations. For seven yeasts with point centromeres, Centurion predicts most of the centromeres at an average of 5~kb distance from their known locations. Finally, we predict centromere coordinates for six yeast species that currently lack centromere annotations. These results suggest that Centurion can be used for centromere identification for a large number of yeast species, even with a limited amount of Hi-C sequencing.

Paper:http://www.ncbi.nlm.nih.gov/pubmed/25940625

More at http://cbio.ensmp.fr/centurion/

Address of the bookmark: http://cbio.ensmp.fr/centurion/

Radka Reifová Lab

Mon, 15 Feb 2016 06:00:48 -0600

We are generally interested in the mechanisms of species origin from a molecular and ecological perspective. Particularly, we are interested in the role of sex chromosomes in speciation. Most of our research is done on birds and mammals. Currently, we focus our research on two hybridizing song birds, the Common nightingale (Luscinia megarhynchos) and the Thrush Nightingale (L. luscinia). Combining population genomic and ecological approaches we try to elucidate the genetic architecture of reproductive isolation and understand the role of interspecific competition and song convergence in the evolution of reproductive isolation between the species.

More at http://web.natur.cuni.cz/~radkas/index.php?page=research

scikit-learn

Jitendra Prajapati — Mon, 29 Feb 2016 17:39:24 -0600

Machine Learning in Python

Simple and efficient tools for data mining and data analysis
Accessible to everybody, and reusable in various contexts
Built on NumPy, SciPy, and matplotlib
Open source, commercially usable - BSD license

More at http://scikit-learn.org/stable/index.html

Address of the bookmark: http://scikit-learn.org/stable/auto_examples/index.html

RA at North-Eastern Hill University

Wed, 02 Mar 2016 08:27:32 -0600

North-Eastern Hill University

Umshing, Shillong- 793 022

Applications are invited for the following positions (purely temporary posts) in an UGC-ISF funded Indo-Israel Joint Research Project entitled “Interactions of mRNA export factors and nuclear pores characterized and quantified by biochemistry, biophysics and high-resolution imaging” sanctioned to Dr. Timir Tripathi, Molecular and Structural Biophysics Laboratory, Department of Biochemistry, NEHU, Shillong for 3 years (2016-19).

Details of positions:

1. Research Associate (two): bioinformatics/computational biology (One) and wet-lab biophysics (one).

2. Junior Research Fellow, JRF (One).

3. Project Assistant (One).

Fellowship: As per GOI rules.

Essential Qualifications:

1. Research Associate: Ph.D. in the above-mentioned fields, should be evident through quality publications. Those who have submitted Ph.D. thesis can also apply.

2. Junior Research Fellow: M.Sc. or equivalent in any branch of life sciences with a good academic record. Prior research experience is desirable.

3. Project Assistant: Graduation in any subject.

Must be familiar with working on computer and MS-Office.

Interested students can apply for the positions online using the following link http://goo.gl/forms/FEa802lNGc , latest by 16.03.16. The hard copy of the application is not required. The date of interview will be informed after primary scrutiny of the applications.

No TA/DA will be paid if called for interview. For any other enquiry email at msb.biochem@gmail.com .

For details of the research work of the PI’s group please visit www.ttripathi.webs.com

Scientist - Computational Genomics (Two Positions)

Sat, 12 Mar 2016 18:07:56 -0600

ICRISAT is a non-profit, non-political organization that conducts agricultural research for development in Asia and sub-Saharan Africa with a wide array of partners throughout the world. Covering 6.5 million square kilometers of land in 55 countries, the semi-arid tropics is home to over 2 billion people, with 650 million of these being the poorest of the poor. ICRISAT and its partners help empower those living in the semi-arid tropics, especially smallholder farmers, to overcome poverty, hunger, malnutrition and a degraded environment through more efficient and profitable agriculture.

ICRISAT is headquartered in Patancheru near Hyderabad, India, with two regional hubs and five country offices in sub-Saharan Africa. ICRISAT, established in 1972, is a member of the CGIAR Consortium. For more details, see www.icrisat.org.

Responsibilities:Design efficient SQL queries for pulling large sequencing projects.
Serve as a technical adviser to the project leadership and provide computational perspective on product design and deliverability.
Develop and oversee a rapid and incremental software development and release schedule.
Design the software architecture, oversee the implementation and evolution of the design on appropriate hardware platforms.
Working collaboratively in a team environment to design, code, test, debug, and document programs for an integrated genomic analysis pipeline in a rapid and incremental software development and release schedule.
Supervise and review code development and ensure that software products meet project objectives in terms of functionality, scalability, robustness and user experience.
Implement and oversee the QA/QC practices to ensure the development team is adhering to quality standards.
Work closely with the application specialist to integrate feedbacks from teams in each CGIAR center into software customization and improvement.
Assist in training of breeders in the CGIAR centers to use software developed.
Personal Profile:

The applicant should have:

Understanding of genomics data and advanced knowledge of Java, and C/C++ as the programming languages and any of the scripting language like perl and/or Python, SQL
High Performance Computing, data architecture, database platforms and QA/QC practices in software engineering.
She/he should have solid experience in software development projects, preferably as a senior programmer or in the software project management role, and in projects involving big data.
Excellent communication skills are needed to work in this multi-disciplinary, multi-location and multi-cultural team.
Ability to mentor colleagues in quality software development practices is desired.
Educational Qualification : Ph. D or Masters Degree in Computational Biology / Computational Genomics or Equivalent with Research Experience in Mentioned Areas.

More at http://www.icrisat.org/careers/

Wellcome Trust/DBT India Alliance Margdarshi Fellowships 2016

Tue, 29 Mar 2016 17:47:39 -0500

The Wellcome Trust/DBT India Alliance invites application for the Margdarshi Fellowship scheme. The scheme provides a unique opportunity for visionary biomedical scientists to lead and nucleate a cutting edge research program in India in collaboration with Indian Host Institution(s). The potential candidates and the Host Institution are encouraged to make a synergistic effort towards establishing a centre of excellence that aims to improve the existing scientific breadth and utilizes the experience of the lead applicant for developing new research platforms. In addition to this, under this programme two eligible Indian institutions may also come together towards creating a new program under the leadership of a visionary scientist.

Eligibility

Interested applicants must

Have around 10 years of experience as independent investigator, and can be of any age or nationality
Have Sponsor(s) at not-for-profit Host Institution(s) in India, who is willing to extend the desired commitment and resources for program implementation
Provisions

The 5 year Fellowship provides

Generous personal support for the Fellow
Salary support for personnel, which may include Assistant Professors
Large quantum of funds for equipment, animals and consumables
Funds to attend scientific gatherings, for collaborative visits and to organize meetings
Overheads for the Host Institution
Process

A joint online application is invited from the Applicant and the Sponsor(s). The details of the scheme and the funding mechanism are available on the website at http://wellcomedbt.org/fellowshiptype/margdarshi-fellowships.

Application form can be accessed at https://fellowships.wellcomedbt.org/Login.aspx

Sponsored applications due by 2 May 2016

Send your inquiries to margdarshi@wellcomedbt.org

PhyloGrapher - Graph Visualization Tool

Jitendra Prajapati — Wed, 06 Apr 2016 19:06:48 -0500

PhyloGrapher is a program designed to visualize and study evolutionary relationships within families of homologous genes or proteins (elements).PhyloGrapher is a drawing tool that generates custom graphs for a given set of elements. In general, it is possible to use PhyloGrapher to visualize any type of relations between elements.

More at http://www.atgc.org/PhyloGrapher/PhyloGrapher_Welcome.html

Address of the bookmark: http://www.atgc.org/PhyloGrapher/PhyloGrapher_Welcome.html