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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/30242?offset=1660</link>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/36512/hisat2-a-fast-and-sensitive-alignment-program-for-mapping-next-generation-sequencing-reads</guid>
	<pubDate>Tue, 08 May 2018 04:27:22 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/36512/hisat2-a-fast-and-sensitive-alignment-program-for-mapping-next-generation-sequencing-reads</link>
	<title><![CDATA[HISAT2: a fast and sensitive alignment program for mapping next-generation sequencing reads]]></title>
	<description><![CDATA[<p><strong>HISAT2</strong><span>&nbsp;is a fast and sensitive alignment program for mapping next-generation sequencing reads (both DNA and RNA) to a population of human genomes (as well as to a single reference genome). Based on an extension of BWT for graphs&nbsp;</span><a href="http://dl.acm.org/citation.cfm?id=2674828">[Sir&eacute;n et al. 2014]</a><span>, we designed and implemented a graph FM index (GFM), an original approach and its first implementation to the best of our knowledge. In addition to using one global GFM index that represents a population of human genomes, HISAT2 uses a large set of small GFM indexes that collectively cover the whole genome (each index representing a genomic region of 56 Kbp, with 55,000 indexes needed to cover the human population). These small indexes (called local indexes), combined with several alignment strategies, enable rapid and accurate alignment of sequencing reads. This new indexing scheme is called a Hierarchical Graph FM index (HGFM).&nbsp;</span></p>
<p><span>more at&nbsp;https://ccb.jhu.edu/software/hisat2/index.shtml</span></p><p>Address of the bookmark: <a href="https://github.com/infphilo/hisat2" rel="nofollow">https://github.com/infphilo/hisat2</a></p>]]></description>
	<dc:creator>Rahul Nayak</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/21537/bioinformatics-project-fellow-at-institute-of-genomics-integrative-biology-new-delhi-delhi</guid>
  <pubDate>Wed, 11 Mar 2015 03:04:38 -0500</pubDate>
  <link></link>
  <title><![CDATA[Bioinformatics Project Fellow at Institute of Genomics &amp; Integrative Biology  - New Delhi, Delhi]]></title>
  <description><![CDATA[
<p>Pay Scale: Rs. 16,000/- + 30 % HRA per month<br />Educational Requirements: M.Sc. in Bioinformatics with at least 55% marks Qualifications: Knowledge of Perl, R and other programming language or Database management or knowledge of pipelines to analyze NGS data or experience in scientific writing and good communication skills </p>

<p>Details will be available at: http://www.igib.res.in/sites/default/files/26032015.pdf </p>

<p>No of Post: 01, 01 </p>

<p>How To Apply: 1. Please fill up the proforma 2. Candidate cannot apply for more than two posts. Last date of receiving application is 12-03-2015. No application would be entertained with “result awaited” status or after due date. List of shortlisted candidates will be put up on CSIR-IGIB website. No TA/DA will be paid to the candidates to attend the interview. The engagement shall be as per guidelines of CSIR/Funding agency. Candidates will have an option to give reply in Hindi. Note: The shortlisted candidates, have to report at 09:00 AM at Mall Road Campus, Delhi – 110007 on the day of interview along with any Photo ID card, (without photo ID card interview will not be conducted). 3 copies of updated signed C. V. (clearly mentioning Date of Birth and Hightest Qualification with percentage), Dissertation (if any), PhD thesis (if any) and original certificates/Self attested photocopies for verification. </p>

<p>General Instructions: Engagement is for the project and on behalf of the funding agency and the tenure shall be as mentioned above. The duration of the post is initially for One year or till the closing date of the project, whichever is earlier. Tenure may be extendable up to project duration. Contract may be terminated at any time by giving one-month notice by either side. The applicants will have no claim implicit or explicit for consideration against any CSIR/IGIB post. Candidates should note that non-fulfillment of the eligibility criterion will result in cancellation of candidature at any stage. </p>

<p>Last Date: 12-03-2015. <br />Age Limit: 28 Years</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/38238/list-of-motif-discovery-tools</guid>
	<pubDate>Tue, 20 Nov 2018 03:54:26 -0600</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/38238/list-of-motif-discovery-tools</link>
	<title><![CDATA[List of motif discovery tools !]]></title>
	<description><![CDATA[<div><div>In genetics, a sequence motif is a nucleotide or amino-acid sequence pattern that is widespread and has, or is conjectured to have, a biological significance. For proteins, a sequence motif is distinguished from a structural motif, a motif formed by the three-dimensional arrangement of amino acids which may not be adjacent.</div><div>&nbsp;</div><div>Following are the list of tools for motif discovery:</div><div>&nbsp;</div><div><a href="http://genius.embnet.dkfz-heidelberg.de/menu/biounit/open-husar/">2Dsweep -- protein annotation by secondary structure elements</a></div><p>Perform secondary structure predictions on protein sequences.</p></div><div><div><a href="http://floresta.eead.csic.es/3dfootprint/">3D-footprint -- database of DNA-binding protein structures</a></div><p>Find binding specificity information about DNA-protein complexes.</p></div><div><div><a href="http://floresta.eead.csic.es/3dfootprint/">3D-footprint: DNA-binding protein database</a></div><p>Find information about the binding specificity of DNA-binding proteins.</p></div><div><div><a href="http://3d-partner.life.nctu.edu.tw/">3D-partner -- a web server to infer interacting partners and binding models</a></div><p>Predict interacting partners and binding models.</p></div><div><div><a href="http://motif.stanford.edu/distributions/3motif/">3MOTIF -- a protein structure visualization system for conserved sequence motifs</a></div><p>Use this web-based sequence motif visualization system to display sequence motif information in its appropriate three-dimensional (3D) context.</p></div><div><div><a href="http://bioinfo.mpiz-koeln.mpg.de/afawe/">AFAWE -- Automatic functional annotation in a distributed Web Services Environment</a></div><p>Protein function prediction and annotation in an integrated environment powered by web service.</p></div><div><div><a href="http://anchor.enzim.hu/">ANCHOR -- Prediction of Protein Binding Regions in Disordered Proteins</a></div><p>Find information about protein binding.</p></div><div><div><a href="http://annie.bii.a-star.edu.sg/annie/home.do">ANNIE -- ANNotation and Interpretation Environment for Protein Sequences</a></div><p>Use to predict function from de novo protein sequences.</p></div><div><div><a href="http://bioinformatica.isa.cnr.it/ASC/">Active Sequences Collection (ASC) database -- A new tool to assign functions to protein sequences</a></div><p>Search for short active protein sequences with demonstrated biological activities.</p></div><div><div><a href="http://blocks.fhcrc.org/">Blocks -- Ungapped segments in conserved protein sequences</a></div><p>Search for ungapped segments corresponding to the most highly conserved regions of proteins.</p></div><div><div><a href="http://cast.engr.uic.edu/">CASTp -- computed atlas of surface topography of proteins with structural and topographical mapping of functionally annotated residues</a></div><p>Identify and measure surface accessible pockets as well as interior inaccessible cavities, for proteins and other molecules.</p></div><div><div><a href="http://www.ebi.ac.uk/thornton-srv/databases/CSA">CSA -- The Catalytic Site Atlas</a></div><p>To search for catalytic residue annotation for enzymes in the Protein Data Bank.</p></div><div><div><a href="http://www.sbg.bio.ic.ac.uk/~confunc/">ConFunc -- Conserved residue Protein Function Prediction Server</a></div><p>Predict protein function using Gene Ontology.</p></div><div><div><a href="http://consurf.tau.ac.il/">ConSurf-DB -- evolutionary conservation profiles of protein structures database</a></div><p>Automatically calculate evolutionary conservation scores of key amino acid residues and map them on protein structures.</p></div><div><div><a href="http://salilab.org/DBAli/">DBAli -- A Database of Structure Alignments</a></div><p>Mine the protein structure space.</p></div><div><div><a href="http://dilimot.embl.de/">DILIMOT -- discovery of linear motifs in proteins</a></div><p>Predict short linear motifs (3-8 residues) in a set of protein sequences.</p></div><div><div><a href="http://www.ebi.ac.uk/dasty/">Dasty2 -- an Ajax protein DAS client</a></div><p>A web client for visualizing protein sequence feature information using DAS.</p></div><div><div><a href="http://genius.embnet.dkfz-heidelberg.de/menu/biounit/open-husar/">DomainSweep -- protein annotation by domain analysis</a></div><p>Identify the domain architecture within a protein sequence.</p></div><div><div><a href="http://e1ds.csbb.ntu.edu.tw/">E1DS -- catalytic site prediction based on 1D signatures of concurrent conservation</a></div><p>Predict enzyme catalytic site.</p></div><div><div><a href="http://elm.eu.org/">ELM -- Eukarotic Linear Motif Resource</a></div><p>Predict functional sites in eukaryotic proteins.</p></div><div><div><a href="http://us.expasy.org/tools/#proteome">EXPASY Proteome Tools Collection</a></div><p>Use a collection of tools for protein analyses.</p></div><div><div><a href="http://us.expasy.org/tools/findmod/">EXPASY-Findmod</a></div><p>Predict potential protein post-translational modifications and find potential single amino acid substitutions in peptides.</p></div><div><div><a href="http://mbs.cbrc.jp/EzCatDB/">EzCatDB -- the Enzyme Catalytic-mechanism Database</a></div><p>Search for information related to the catalytic mechanisms of enzymes.</p></div><div><div><a href="http://bioinf.cs.ucl.ac.uk/ffpred/">FFPred -- feature-based function prediction</a></div><p>An integrated feature-based function prediction server for vertebrate proteomes.</p></div><div><div><a href="http://www.ebi.ac.uk/printsscan/">FingerPRINT Scan</a></div><p>Identify the closest matching PRINTS sequence motif fingerprints in a protein sequence.</p></div><div><div><a href="http://firedb.bioinfo.cnio.es/">FireDB -- a database of functionally important residues from proteins of known structure</a></div><p>Search for functional annotation of important sites in proteins with known structures.</p></div><div><div><a href="http://bioserv.rpbs.univ-paris-diderot.fr/cgi-bin/Frog2">Frog2 -- a FRee Online druG 3D conformation generator</a></div><p>Produce 3D conformations of small drug compounds.</p></div><div><div><a href="http://www.hgpd.jp/">HGPD -- Human Gene and Protein Database</a></div><p>A database presenting experiment-based results in human proteomics.</p></div><div><div><a href="http://hhsenser.tuebingen.mpg.de/">HHsenser -- exhaustive transitive profile search using HMMx96HMM comparison</a></div><p>Conduct exhaustive intermediate profile searches of a set of homologous protein sequences.</p></div><div><div><a href="http://loschmidt.chemi.muni.cz/hotspotwizard/">HotSpot Wizard -- Substrate Specificity Hot Spot Identification web server</a></div><p>Design protein mutations in site-directed mutagenesis.</p></div><div><div><a href="http://phylogenomics.berkeley.edu/intrepid/">INTREPID -- INformation-theoretic TREe traversal for Protein functional site IDentification</a></div><p>Use for protein functional site identification.</p></div><div><div><a href="http://www.cbs.dtu.dk/">Integrating protein annotation resources through the Distributed Annotation System</a></div><p>Annotate protein using this integrated annotation resource.</p></div><div><div><a href="http://www.ebi.ac.uk/InterProScan/">InterProScan -- protein domains identifier</a></div><p>Identify protein family (and DNA) domains, patterns, motifs, protein families, and functional sites.</p></div><div><div><a href="http://kfc.mitchell-lab.org/">KFC -- Knowledge-based FADE and Contacts</a></div><p>Interactive forecasting of protein interaction hot spots.</p></div><div><div><a href="http://biominer.bime.ntu.edu.tw/magiicpro/">MAGIIC-PRO -- detecting functional signatures by efficient discovery of long patterns in protein sequences</a></div><p>Discover long patterns in protein sequences.</p></div><div><div><a href="http://prodata.swmed.edu/malisam">MALISAM -- Manual ALIgnments for Structurally Analogous Motifs</a></div><p>Database containing pairs of structural analogs and their alignments.</p></div><div><div><a href="http://meme.nbcr.net/">MEME -- discovering and analyzing DNA and protein sequence motifs</a></div><p>Find sequence patterns in DNA and protein sequences.</p></div><div><div><a href="http://www.nii.res.in/modpropep.html">MODPROPEP -- a program for knowledge-based modeling of protein-peptide complexes</a></div><p>A web server for knowledge-based modeling of protein-peptide complexes, specifically peptides in complex with major histocompatibility complex (MHC) proteins and kinases.</p></div><div><div><a href="http://www.bioinfo.tsinghua.edu.cn/~tigerchen/memo.html">MeMo -- a web tool for prediction of protein methylation modifications</a></div><p>Predict protein methylation sites.</p></div><div><div><a href="http://caps.ncbs.res.in/MegaMotifbase/index.html">MegaMotifBase -- a database of structural motifs in protein families and superfamilies</a></div><p>Find structural segments or motifs for protein structures.</p></div><div><div><a href="http://mnm.engr.uconn.edu/MNM/SMSSearchServlet">Minimotif Miner -- a tool for investigating protein function</a></div><p>Find motifs in a protein sequence.</p></div><div><div><a href="http://umber.sbs.man.ac.uk/dbbrowser/motif3d/motif3d.html">Motif3D -- Relating protein sequence motifs to 3D structure</a></div><p>Visualize protein sequence motifs on the 3D protein structures.</p></div><div><div><a href="http://myhits.isb-sib.ch/cgi-bin/motif_scan">MotifScan</a></div><p>Find presence of any known protein motif (Prosite and Pfam) in a protein sequence.</p></div><div><div><a href="http://bioinfo3d.cs.tau.ac.il/MultiBind">MultiBind -- Multiple Alignment of Protein Binding Sites</a></div><p>Recognize spatial chemical binding patterns common to a set of protein structures.</p></div><div><div><a href="http://mendel.imp.univie.ac.at/myristate/SUPLpredictor.htm">NMT -- The MYR Predictor</a></div><p>Analyze proteins for the presence of N-terminal N-myristoylation site.</p></div><div><div><a href="http://www.cbs.dtu.dk/services/NetNGlyc/">NetNGlyc -- N-Glycosylation sites prediction tool</a></div><p>Find the presence of N-Glycosylation sites in human proteins.</p></div><div><div><a href="http://www.cbs.dtu.dk/services/NetOGlyc/">NetOGly 3.1 -- O-glycosylation sites prediction tool</a></div><p>Find the presence of O-GalNAc (mucin type) glycosylation sites in mammalian proteins.</p></div><div><div><a href="http://www.cbs.dtu.dk/services/NetPhos/">NetPhos 2.0 -- Phosphorylation sites predictions</a></div><p>Analyze eukaryotic proteins for the presence of serine, threonine and tyrosine phosphorylation sites.</p></div><div><div><a href="http://www.cbs.dtu.dk/services/NetPhosK/">NetPhosK 1.0 Server -- kinase specific eukaryotic protein phosphorylation sites prediction tool</a></div><p>Find possible kinase specific phosphorylation sites in eukaryotic proteins.</p></div><div><div><a href="http://networkin.info/search.php">NetworKIN -- a resource for exploring cellular phosphorylation networks</a></div><div>&nbsp;</div></div><div><div><a href="http://neuroproteomics.scs.uiuc.edu/neuropred.html">NeuroPred -- a tool to predict cleavage sites in neuropeptide precursors and provide the masses of the resulting peptides</a></div><p>Predict cleavage sites at basic amino acid locations in neuropeptide precursor sequences.</p></div><div><div><a href="http://www.ebi.ac.uk/patentdata/nr/">Non-Redundant Patent Sequences - Patented Sequence Database</a></div><p>Find information about patented nucleotide and protein sequences.</p></div><div><div><a href="http://www.cbs.dtu.dk/databases/OGLYCBASE/">O-GLYCBASE</a></div><p>Search for information about glycoproteins with O-linked and C-linked glycosylation sites.</p></div><div><div><a href="http://www.pandora.cs.huji.ac.il/">PANDORA -- Protein ANnotation Diagram ORiented Analysis</a></div><p>Find information about protein sequence annotations.</p></div><div><div><a href="http://sunserver.cdfd.org.in:8080/protease/PAR_3D/index.html">PAR-3D -- Protein Active site Residue - 3D structural motif</a></div><p>A server to predict protein active site residues.</p></div><div><div><a href="http://wwwmgs.bionet.nsc.ru/mgs/gnw/pdbsite/">PDBSite -- a database of the 3D structure of protein functional sites</a></div><p>Search for structural and functional information on the protein functional sites.</p></div><div><div><a href="http://wwwmgs.bionet.nsc.ru/mgs/systems/fastprot/pdbsitescan.html">PDBSiteScan -- A program for searching for active, binding and posttranslational modification sites in the 3D structures of proteins</a></div><p>Search 3D protein fragments similar in structure to known active, binding and posttranslational modification sites.</p></div><div><div><a href="http://pedant.gsf.de/">PEDANT -- Protein Extraction, Description and ANalysis Tool</a></div><p>Conduct genome wide functional and structural analysis.</p></div><div><div><a href="http://phosida.org/">PHOSIDA -- Phosphorylation site database</a></div><p>Search for phosphorylation data of any protein of interest.</p></div><div><div><a href="http://www.phosphorylation.biochem.vt.edu/">PHOSPHORYLATION SITE DATABASE</a></div><p>Search for information on prokaryotic proteins that undergo serine, threonine, or tyrosine phosphorylation.</p></div><div><div><a href="http://www.jcvi.org/pn-utility/web/smarty_wrapper/about.php">PNU -- Protein Naming Utility</a></div><p>Determine correct names for proteins.</p></div><div><div><a href="http://mbs.cbrc.jp/poodle/poodle-s.html">POODLE-S -- Predicition Of Order and Disorder by machine LEarning</a></div><p>Web application for predicting protein disorder by using physicochemical features and reduced amino acid set of a position-specific scoring matrix.</p></div><div><div><a href="http://gemdock.life.nctu.edu.tw/ppisearch/">PPISearch -- Protein-Protein Interaction Search</a></div><p>Find homologous protein-protein interactions across multiple species.</p></div><div><div><a href="http://www.ebi.ac.uk/ppsearch/">PPSearch</a></div><p>Search your query sequence against PROSITE pattern database for protein motifs.</p></div><div><div><a href="http://pridb.gdcb.iastate.edu/">PRIDB -- Protein-RNA Interface DataBase</a></div><p>Find information about protein-RNA complexes from the Protein Data Bank (PDB).</p></div><div><div><a href="http://umber.sbs.man.ac.uk/dbbrowser/PRINTS/">PRINTS and its automatic supplement, prePRINTS -- A compendium of protein fingerprints</a></div><p>Search for protein fingerprints.</p></div><div><div><a href="http://www.expasy.org/prosite/">PROSITE</a></div><p>Identify protein families and domains for a given protein sequence.</p></div><div><div><a href="http://www.imtech.res.in/raghava/prrdb/">PRRDB -- Pattern Recognition Receptor Database</a></div><p>A comprehensive database of pattern-recognition receptors and their ligands.</p></div><div><div><a href="http://www.arabidopsis.org/cgi-bin/patmatch/nph-patmatch.pl">PatMatch -- a program for finding patterns in peptide and nucleotide sequences</a></div><p>Search for short nucleotide or peptide sequences such as cis-elements in nucleotide sequences or small domains and motifs in protein sequences.</p></div><div><div><a href="http://pepcyber.umn.edu/PPEP/">PepCyber:P~PEP -- a database of human protein protein interactions mediated by phosphoprotein-binding domains</a></div><p>Database specialized in documenting human PPBD-containing proteins and PPBD-mediated interactions.</p></div><div><div><a href="http://us.expasy.org/tools/peptidecutter/">PeptideCutter -- protein cleavage sites prediction tool</a></div><p>Predicts potential protease cleavage sites and sites cleaved by chemicals in a given protein sequence.</p></div><div><div><a href="http://phobius.binf.ku.dk/">Phobius -- A combined transmembrane topology and signal peptide predictor</a></div><p>Predict combined transmembrane topology and signal peptides.</p></div><div><div><a href="http://phospho.elm.eu.org/">Phospho.ELM -- a database of phosphorylation sites</a></div><p>Search for eukaryotic phosphorylation sites.</p></div><div><div><a href="http://www.phospho3d.org/">Phospho3D -- a database of three-dimensional structures of protein phosphorylation sites</a></div><p>Search for 3D structure and functional annotation of phosphorylation sites in proteins.</p></div><div><div><a href="http://www.phosphosite.org/">PhosphoSite -- A bioinformatics resource dedicated to physiological protein phosphorylation.</a></div><p>Search the database of in vivo phosphorylation sites of human and mouse proteins</p></div><div><div><a href="http://pxgrid.med.monash.edu.au/polyq/">PolyQ -- Polyglutamine Database</a></div><p>Find information about polyglutamine (polyQ) repeats.</p></div><div><div><a href="http://www.ebi.ac.uk/pratt/">Pratt Protein motif and pattern discovery</a></div><p>Find the presence of protein motifs and patterns in an amino acid sequence.</p></div><div><div><a href="http://www.predisi.de/">PrediSi -- Prediction of Signal Peptides and their Cleavage Positions</a></div><p>Predict signal peptide sequences and their cleavage positions in bacterial and eukaryotic amino acid sequences.</p></div><div><div><a href="http://www.ebi.ac.uk/thornton-srv/databases/ProFunc/">ProFunc -- a server for predicting protein function from 3D structure</a></div><p>Predict protein functions based on known structures.</p></div><div><div><a href="http://bioinfo41.weizmann.ac.il/promate/promateus.html">ProMateus--an open research approach to protein-binding sites analysis</a></div><p>Predict the location of potential protein-protein binding sites for unbound proteins.</p></div><div><div><a href="http://www.proteus.cs.huji.ac.il/">ProTeus -- identifying signatures in protein termini</a></div><p>Identify short linear signatures in protein termini.</p></div><div><div><a href="http://genius.embnet.dkfz-heidelberg.de/menu/cgi-bin/w2h-open/w2h.open/w2h.startthis?SIMGO=w2h%2ewelcome">ProtSweep -- protein annotation by homology</a></div><p>Analyze and identify newly obtained protein sequences.</p></div><div><div><a href="http://protemot.csbb.ntu.edu.tw/">Protemot -- prediction of protein binding sites with automatically extracted geometrical templates</a></div><p>Predict protein binding sites in a protein sequence based on geometrical analysis of protein tertiary substructures.</p></div><div><div><a href="http://quasimotifinder.tau.ac.il/">QuasiMotiFinder -- protein annotation by searching for evolutionarily conserved motif-like patterns</a></div><p>Search for evolutionarily conserved motif-like patterns in protein sequences.</p></div><div><div><a href="http://bindr.gdcb.iastate.edu/RNABindR">RNABindR -- software for prediction of RNA binding residues in proteins</a></div><p>Web-based server for analyzing and predicting RNA binding sites in proteins.</p></div><div><div><a href="http://caps.ncbs.res.in/scanmot/scanmot.html">SCANMOT -- searching for similar sequences using a simultaneous scan of multiple sequence motifs</a></div><p>Search for similarities between proteins by simultaneous matching of multiple motifs.</p></div><div><div><a href="http://bioinf.fbb.msu.ru/SDPpred/">SDPpred -- A Tool for Prediction of Amino Acid Residues that Determine Differences in Functional Specificity of Homologous Proteins</a></div><p>Predict residues in protein sequences that determine the proteins' functional specificity.</p></div><div><div><a href="http://tamm.mit.edu/SDR/">SDR -- Specificity Determining Residues Database</a></div><p>Predict specificity-determining residues in protein families.</p></div><div><div><a href="http://bioware.ucd.ie/~slimdisc/">SLiMDisc -- Short, Linear Motif Discovery</a></div><p>Find shared motifs in proteins with a common attribute.</p></div><div><div><a href="http://sumosp.biocuckoo.org/">SUMOsp -- a web server for sumoylation site prediction</a></div><p>Conduct in silico sumoylation sites prediction.</p></div><div><div><a href="http://oxytricha.princeton.edu/SWAKK/">SWAKK -- a web server for detecting positive selection in proteins using a sliding window substitution rate analysis</a></div><p>Detect protein sequence section under positive evolution selection.</p></div><div><div><a href="http://www.expasy.org/tools/scanprosite/">ScanProsite</a></div><p>Search for motifs and patterns within protein sequences.</p></div><div><div><a href="http://www.expasy.org/tools/scanprosite/">ScanProsite -- detection of PROSITE signature matches and ProRule-associated functional and structural residues in proteins</a></div><p>Detect patterns, profiles and motifs in a protein sequence.</p></div><div><div><a href="http://scansite.mit.edu/">ScanSite 2.0 -- Proteome-wide prediction of cell signaling interactions using short sequence motifs</a></div><p>Search for motifs within proteins that are likely to be phosphorylated by specific protein kinases or bind to domains such as SH2 domains, 14-3-3 domains or PDZ domains.</p></div><div><div><a href="http://sepresa.bio-x.cn/">SePreSA -- SErver for the PREdiction of populations susceptible to Serious Adverse drug reaction</a></div><p>Find information about populations carrying polymorphisms within protein binding pockets that make them susceptible to serious adverse drug reaction (SADR).</p></div><div><div><a href="http://motif.genome.jp/">Sequence Motif Search</a></div><p>Search the presence of a motif in either amino acid sequence or nucleotide sequence.</p></div><div><div><a href="http://www.csbio.sjtu.edu.cn/bioinf/Signal-3L/">Signal-3L -- A 3-layer approach for predicting signal peptides</a></div><p>Predict signal peptides.</p></div><div><div><a href="http://www.cbs.dtu.dk/services/SignalP/">SignalP -- Machine learning approaches to the prediction of signal peptides, their cleavage sites, and other protein sorting signals</a></div><p>Predict signal peptides and their cleavage sites.</p></div><div><div><a href="http://us.expasy.org/tools/sulfinator/">Sulfinator -- tyrosine sulfation sites prediction tool</a></div><p>Predict the presence of tyrosine sulfation sites in protein sequences</p></div><div><div><a href="http://bioinf-services.charite.de/supersite/">SuperSite -- Ligand Binding Site Database</a></div><p>Look at protein structure from a ligand and binding site perspective.</p></div><div><div><a href="http://www.ch.embnet.org/">Swiss EMBnet node web server</a></div><p>Use a collection of bioinformatics tools at this portal site.</p></div><div><div><a href="http://bioinfo.montp.cnrs.fr/?r=t-reks">T-REKS -- identification of Tandem REpeats in sequences with a K-meanS based algorithm</a></div><p>Find information about tandem repeats in proteins that carry fundamental biological functions and are related to a number of human diseases.</p></div><div><div><a href="http://tmbeta-genome.cbrc.jp/TMFunction/">TMFunction -- The Functional Database of Membrane Proteins</a></div><p>Find information about functional residues in alpha-helical and beta-barrel membrane proteins.</p></div><div><div><a href="http://topdom.enzim.hu/">TOPDOM -- Conservatively Located Domains and Motifs in Transmembrane Proteins</a></div><p>Database of domains and motifs with conservative location in transmembrane proteins.</p></div><div><div><a href="http://motif.stanford.edu/distributions/emotif/">The EMOTIF database</a></div><p>Search for highly conserved and specific protein sequence motifs.</p></div><div><div><a href="http://treedetv2.bioinfo.cnio.es/treedet/index.html">TreeDet -- Predicting Functional Residues in Protein Sequence Alignments</a></div><p>Predict functional sites in protein sequence alignments use different methodologies.</p></div><div><div><a href="http://motif.bmi.ohio-state.edu/ChIPMotifs/">W-ChIPMotifs -- ChIP-based protein Motif discovery web server</a></div><p>Find de novo protein motifs from chromatin immunoprecipitation data.</p></div><div><div><a href="http://feature.stanford.edu/webfeature/">WebFEATURE -- an interactive web tool for identifying and visualizing functional sites on macromolecular structures</a></div><p>Scan query structures for functional sites in both proteins and nucleic acids.</p></div><div><div><a href="http://wwwmgs.bionet.nsc.ru/mgs/programs/panalyst/">WebProAnalyst -- an interactive tool for analysis of quantitative structurex96activity relationships in protein families</a></div><p>Analyze quantitative structure-activity relationship of related protein families.</p></div><div><div><a href="http://motif.stanford.edu/distributions/eblocks/">eBLOCKs -- enumerating conserved protein blocks to achieve maximal sensitivity and specificity</a></div><p>Search for ungapped alignments of highly conserved regions among a protein family or superfamily.</p></div><div><div><a href="http://ef-site.hgc.jp/eF-seek/">eF-seek -- prediction of the functional sites of proteins by searching for similar electrostatic potential and molecular surface shape</a></div><p>Predict the functional sites of proteins.</p></div><div><div><a href="http://firedb.bioinfo.cnio.es/Php/FireStar.php">firestar -- prediction of functionally important residues using structural templates and alignment reliability</a></div><p>An expert system for predicting ligand-binding residues in protein structures.</p></div><div><div><a href="http://caps.ncbs.res.in/imotdb/">iMOTdb -- a comprehensive collection of spatially interacting motifs in proteins</a></div><p>Automatically identify spatially interacting motifs among distantly related proteins sharing similar folds and possessing common ancestral lineage.</p></div>]]></description>
	<dc:creator>Neel</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/33617/list-of-universities-offering-bachelor-or-master-bioinformatics-degree-in-pakistan</guid>
	<pubDate>Wed, 21 Jun 2017 04:20:43 -0500</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/33617/list-of-universities-offering-bachelor-or-master-bioinformatics-degree-in-pakistan</link>
	<title><![CDATA[List of universities offering Bachelor or Master bioinformatics degree in Pakistan]]></title>
	<description><![CDATA[<p>There are a lot of universities offering Bachelor or Master degree in Pakistan. Following are the list of few intitute/universities</p><p>Bachelor/ BS Bioinformatics at<br />1. Al-khair University, Bhimber<br />2. Government College University, Faisalabad<br />3. University Of Agriculture, Faisalabad<br />4. Comsats Institute Of Information Technology [isb], Islamabad<br />5. International Islamic University, Islamabad<br />6. Quaid-e-azam University, Islamabad<br />7. Khushal Khan Khattak University, Karak<br />8. Virtual University Of Pakistan, Lahore<br />9. Virtual University Of Pakistan, Lahore<br />10. Hazara University, Mansehra<br />11. Shaheed Benazir Bhutto Women University, Peshawar<br />12. Comsats Institute Of Information Technology, Sahiwal<br />13. Capital University Of Science And Technology, Islamabad<br />14. Foundation University, Islamabad<br />15. Baqai Medical University/hospital, Karachi<br />16. Institute Of Business And Technology(main Campus), Karachi<br />17. Sir Syed University Of Engineering &amp; Technology, Karachi<br />18. Forman Christian College, Lahore<br />19. Qarshi University (lhr), Lahore<br />20. The Superior University, Lahore<br />21. University Of Management And Technology, Lahore<br />22. Federal Institute Of Health Sciences, Lahore<br />23. Shaheed Benazir Bhutto Women University Peshawar, Sub Campus, Swabi<br />24. Government Postgraduate College ( Mandian), Abbottabad<br />25. Federal Institute Of Health Sciences, Multan<br />26. Fedral Institute Of Health Sciences, Muzaffarabad<br />27. The Limit Institution Of Health Sciences, Sahiwal</p><p><br />Master/ MS Bioinformatics cources at<br />1. Government College University, Faisalabad<br />2. Comsats Institute Of Information Technology [isb], Islamabad<br />3. International Islamic University, Islamabad<br />4. National University Of Science &amp; Technology, Islamabad<br />5. Quaid-e-azam University, Islamabad<br />6. University Of Sindh, Jamshoro<br />7. Virtual University Of Pakistan, Lahore<br />8. Hazara University, Mansehra<br />9. Shaheed Benazir Bhutto Women University, Peshawar<br />10. Capital University Of Science And Technology, Islamabad<br />11. Cecos University Of Information Tech. &amp; Emerging Sciences, Peshawar</p><p>The real bioinformatics scope lies if there are research labs which work in this field. One has to take account of that. If so then try to get information of those labs and visit them to get a hang of the work they pursue.</p><p>There is a huge buzz of precision medicine in light of genomics all around the world. One should also try to see how genomics infrastructure is built up or standing in Pakistan. If research labs having collaboration with hospitals employ genomics then one must also visit such labs. This will bring new avenues in healthcare advances. Not only it opens up the wealth of knowledge one can make out of genomics study but will also advance the critical thinking of therapies.</p><p>So I would encourage to target research labs working in the fields and also get information of hospitals employing genomics, this will give you an overall understanding of the fields demand in your country.</p>]]></description>
	<dc:creator>Reshma Khatun</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/42023/encode3-a-collection-of-research-articles-and-related-content-describing-the-encyclopedia-of-dna-elements-its-datasets-and-tools</guid>
	<pubDate>Sat, 08 Aug 2020 08:25:21 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/42023/encode3-a-collection-of-research-articles-and-related-content-describing-the-encyclopedia-of-dna-elements-its-datasets-and-tools</link>
	<title><![CDATA[ENCODE3: A collection of research articles and related content describing the Encyclopedia of DNA Elements, its datasets and tools.]]></title>
	<description><![CDATA[<p>How cells, tissues and organisms interpret the information encoded in the genome has vital implications for our understanding of development, health and disease. Launched in 2003, the ENCyclopedia Of DNA Elements (ENCODE) project has the aim of mapping the functional elements in the human genome (later expanded to include model organisms).</p><p>During the first phase of ENCODE, published in 2007, microarray-based technologies were used to detect regions associated with transcription factors, certain histone modifications and open chromatin within a pre-specified 1% of the human genome.</p><p>ENCODE&rsquo;s second phase saw a switch to sequencing-based technologies, the addition of new assay types and the analysis of functional elements genome-wide, described in a collection of research articles in 2012.</p><p><span>The&nbsp;</span><a href="https://www.nature.com/articles/s41586-020-2493-4">Encyclopedia paper of ENCODE 3</a><span>, published in&nbsp;</span><em>Nature</em><span>, gives an overview of the various assays that were performed in human and mouse cell lines and tissues and describes a Registry of human and mouse candidate&nbsp;</span><em>cis</em><span>-regulatory elements (cCREs).</span></p><p>More at&nbsp;<a href="https://www.nature.com/immersive/d42859-020-00027-2/index.html">https://www.nature.com/immersive/d42859-020-00027-2/index.html</a></p>]]></description>
	<dc:creator>Shruti Paniwala</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/23537/research-associate-bioinformatics-central-institute-for-research-on-buffaloes-cirb-hisar-haryana</guid>
  <pubDate>Fri, 31 Jul 2015 10:19:45 -0500</pubDate>
  <link></link>
  <title><![CDATA[Research Associate Bioinformatics Central Institute for Research on Buffaloes (CIRB) - Hisar, Haryana]]></title>
  <description><![CDATA[
<p>Research Associate (RA) under Network Project on Agricultural Bioinformatics</p>

<p>Name of the Project : Network Project on Agricultural Bioinformatics Number of positions One<br />Qualifications : Ph.D Degree in Bioinformatics/Biotechnology/ Biochemistry/Genetics &amp; Breeding/Life Sciences OR Master’s Degree in relevant subject with at least 2 years research experience. Desirable : Working experience in Molecular Biology/Genomics/Bioinformatics, specifically, sequence data analysis using software’s proficiently</p>

<p>Emoluments : Masters Degree Holders Rs. 38,000/- per month Doctoral Degree Holders Rs. 40,000/- per month</p>

<p>Emoluments : Rs.25000/- per month for 1st and 2nd year and Rs. 28000/- per month for 3rd year<br />Age Limit : Upper age limit is 35 years for men and 40 years for women on the date of interview. Age relaxation for SC/ST and OBC candidates as per rules</p>

<p>More at http://www.cirb.res.in/attachments/195_walk-in-interview%20for%20contractual%20positions%20of%20RA%20and%20SRF%20%28On%20Dated%2011.8.2015%29.pdf</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/44288/upset-plots</guid>
	<pubDate>Fri, 24 Mar 2023 22:30:23 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/44288/upset-plots</link>
	<title><![CDATA[Upset plots !]]></title>
	<description><![CDATA[<p>Upset plots are a type of visualization used to analyze the intersection of sets or categories. They are particularly useful for displaying data with multiple categories and analyzing their overlaps.</p>
<p>In an upset plot, each row represents a category or set, and each column represents a data point. The length of the bar for each category indicates the number of data points that belong to that category. The plot also shows the intersections between categories, represented by overlapping bars.</p>
<p>Upset plots are useful for visualizing complex data with multiple categories and intersections, and can help identify patterns and relationships between categories. They are often used in fields such as bioinformatics, where they can be used to analyze gene expression data or to compare the results of different experimental conditions.</p>
<p>https://jokergoo.github.io/ComplexHeatmap-reference/book/upset-plot.html#example-with-the-genomic-regions</p><p>Address of the bookmark: <a href="https://jokergoo.github.io/ComplexHeatmap-reference/book/upset-plot.html#example-with-the-genomic-regions" rel="nofollow">https://jokergoo.github.io/ComplexHeatmap-reference/book/upset-plot.html#example-with-the-genomic-regions</a></p>]]></description>
	<dc:creator>BioStar</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/21022/ra-bioinformatics-at-tezpur-university</guid>
  <pubDate>Fri, 06 Feb 2015 04:11:23 -0600</pubDate>
  <link></link>
  <title><![CDATA[RA Bioinformatics at TEZPUR UNIVERSITY]]></title>
  <description><![CDATA[
<p>Walk-in-interview will be held on 23 February, 2015 at 11.00 a.m. for the following temporary positions in the DBT (U-EXCEL) sponsored project entitled “Sequencing genomes of some bacteria that invade/resides in tomato plant” under the Principal Investigator Dr. Suvendra Kumar Ray, Department of Molecular Biology and Biotechnology, Tezpur University.</p>

<p>Interested candidates may appear before the interview board on 23 February, 2015 at the Office of the Head, Department of Molecular Biology &amp; Biotechnology, Tezpur University with original documents and photocopies of marks sheets, certificates, testimonials, caste certificate (if applicable), experience certificate and a copy of curriculum vitae (CV) duly signed by the candidate.</p>

<p>Position: One (01) Research Associate.</p>

<p>Educational Qualification: Candidates having Ph.D. degree or submitted thesis in any topic of Life Science Areas (Zoology, Botany, Microbiology, Biotechnology etc.) along with knowledge of gene and protein sequence analysis may apply.</p>

<p>Remuneration: Rs. 22,000/- (Rupees twenty two thousand) only + 10% HRA as admissible per month for the first year and Rs. 23,000/- (Rupees twenty three thousand) only + 10% HRA as admissible per month for the second year.</p>

<p>Age: Candidate preferably below the age of 40 years who have obtained a doctorate (Ph.D.) degree from a recognized University.</p>

<p>Upper age limit may be relaxed up to 5 years in the case of candidates belonging SC/ST/OBC/Women and physically challenged.</p>

<p>Position: One (01) Project Assistant.</p>

<p>Educational Qualification: B.Sc./B.Tech./B.E./B.Pharma in any branch with minimum 55% mark in the qualifying examinations and minimum 50 % mark in 10th and 10+2 Science examinations.</p>

<p>Remuneration: Rs. 8,000/- (Rupees eight thousand) only per month (consolidated). Age: Candidate should not be more than 28 years of age on the date of interview. Upper age limit may be relaxed up to 5 years in the case of candidate belonging to SC/ST/OBC/Women/Physically Challenged.</p>

<p>Duration: One year or till completion of the project, whichever is earlier. N.B. No TA/DA will be paid to the candidates for attending the interview.</p>

<p>For further information contact – Dr. Suvendra Kumar Ray, Associate Professor Email: suven@tezu.ernet.in Department of Molecular Biology and Biotechnology Tezpur University Sd/- Dean, Research &amp; Development Tezpur University</p>

<p>Advertisement: http://www.tezu.ernet.in/ProjectWalkin/Advt-SKR2-5342-A.pdf</p>
]]></description>
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<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/33820/circular-visualization-in-r</guid>
	<pubDate>Wed, 05 Jul 2017 04:11:30 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/33820/circular-visualization-in-r</link>
	<title><![CDATA[Circular Visualization in R]]></title>
	<description><![CDATA[<p>This is the documentation of the&nbsp;<a href="https://cran.r-project.org/package=circlize"><span>circlize</span></a>&nbsp;package. Examples in the book are generated under version 0.4.1.</p>
<p>If you use&nbsp;<span>circlize</span>&nbsp;in your publications, I would be appreciated if you can cite:</p>
<p>Gu, Z. (2014) circlize implements and enhances circular visualization in R. Bioinformatics. DOI:&nbsp;<a href="https://doi.org/10.1093/bioinformatics/btu393">10.1093/bioinformatics/btu393</a></p><p>Address of the bookmark: <a href="http://zuguang.de/circlize_book/book/" rel="nofollow">http://zuguang.de/circlize_book/book/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/21095/ra-walk-in-interview-actrec</guid>
  <pubDate>Mon, 09 Feb 2015 01:06:16 -0600</pubDate>
  <link></link>
  <title><![CDATA[RA WALK-IN-INTERVIEW @ ACTREC]]></title>
  <description><![CDATA[
<p>No. ACTREC/Advt./ 7 /2015</p>

<p>Title of the Project<br />Research Associate<br />(One position)<br />DBTs Biotechnology/Bioinformatics training centre<br />PI Dr. Ashok Varma	</p>

<p>Duration of the Project Six Months from the date of appointment, can be extended further for six month.</p>

<p>Date &amp; Time: 17th February, 2015 at 10.00 a.m.</p>

<p>Venue: Meeting Room, 3rd floor, Khanolkar Shodhika, ACTREC</p>

<p>Essential Qualifications and Experience:</p>

<p>Ph.D. Degree in Basic Sciences from recognized University. Research experience in Bioinformatics or on gene cloning, protein purification, and crystallization.</p>

<p>*M.Sc. degree obtained after a one year course will not be considered.</p>

<p>Selected candidate will have to join at the earliest.</p>

<p>Consolidated Salary: Rs.28,600/- p.m. {Rs.22,000/- + 30% HRA}</p>

<p>The work progress of the candidate will be monitored and extension after 6 months will depend on satisfactory progress of the work.</p>

<p>Candidates fulfilling these requirements should pre-register by sending their application in the prescribed format with recent CV and contact details of 2 referees by e-mail to ‘program.office@actrec.gov.in’ latest by 17.00 hrs on 12-02-2015.<br />The interviews would be held on 17th February, 2015 and will be only for the pre-registered candidates. Candidates should report between 09.30 to 10.00 a.m. in Steno Pool, 3rd floor, Khanolkar Shodhika, ACTREC, Kharghar, Navi Mumbai.<br />No T.A./D.A. will be admissible for attending the interview.</p>

<p>At the time of Interview the candidate should bring original certificates along with CV with contact details of 2 referees and submit the photocopies (attested) of the certificates, with a recent passport size photograph.</p>

<p>All correspondence should be strictly made only to ‘program.office@actrec.gov.in’ as indicated.</p>

<p>Advertisement: www.actrec.gov.in/data%20files/2015/AV-RA-DBT-28-1-15.docx</p>
]]></description>
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