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<channel>
	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/30304?offset=840</link>
	<atom:link href="https://bioinformaticsonline.com/related/30304?offset=840" rel="self" type="application/rss+xml" />
	<description><![CDATA[]]></description>
	
	
<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/30825/open-positions-in-pasini%E2%80%99s-lab</guid>
  <pubDate>Sat, 04 Feb 2017 08:17:18 -0600</pubDate>
  <link></link>
  <title><![CDATA[Open Positions in Pasini’s lab]]></title>
  <description><![CDATA[
<p>Computational Biologists<br />Open to PhD-student and Post-doc candidates<br />We are looking for wet and computational biologists to work on an ERC funded project in our<br />laboratory located at the Department of Experimental Oncology of the European Institute of<br />Oncology in Milan (Italy). The project will focus on different aspects of the function of Polycomb<br />Group proteins and other chromatin modifying activities in relation to their role in regulating cellular<br />identity in the development of adult tissues.<br />The candidates will be in charge of computational analysis and data management related to the<br />project. She/he will directly interact with the wet scientists working in our laboratory while working<br />embedded in the community of computational biologists present at our institution. The work will<br />involve the analysis of sequencing data produced with cutting edge technologies to study gene<br />expression and chromatin environment including data produced on rare cell populations and single<br />cells. The applicants must have a good knowledge of programming in python/perl/java along with<br />strong statistical background and performing analysis in R platform. A biological background is<br />also recommended however it’s not mandatory for application.<br />Each applicant should submit a full CV (with a detailed description of her/his background,<br />expertise, achievements and publication records) together with a letter of intent and at least two<br />contacts for recommendations (for a post-doc position). Competitive salary will be offered based<br />on the experience of the candidate. Non Italian as well as Italian applicants that have been working<br />outside Italy (&gt;3yrs.) will have the opportunity to benefit of a full tax deduction for the first three<br />years of contract.<br />Applications should be submitted as single PDF to diego.pasini@ieo.it</p>

<p>Lab https://www.ieo.it/en/RESEARCH/People/Researchers/Pasini-Diego/</p>
]]></description>
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<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/30897/finestructure-v2-globetrotter</guid>
	<pubDate>Mon, 13 Feb 2017 08:40:23 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/30897/finestructure-v2-globetrotter</link>
	<title><![CDATA[fineSTRUCTURE v2 &amp; GLOBETROTTER]]></title>
	<description><![CDATA[<p>Software available at this site</p>
<div>
<ul>
<li><a href="https://people.maths.bris.ac.uk/%7Emadjl/finestructure/finestructure_info.html">FineSTRUCTURE version 2</a>, a pipeline for running ChromoPainter and FineSTRUCTURE for population inference. A GUI is available for interpretation. Download from the <a href="https://people.maths.bris.ac.uk/%7Emadjl/finestructure/finestructure.html">Downloads</a> page.</li>
<li><a href="https://people.maths.bris.ac.uk/%7Emadjl/finestructure/finestructureR.html">FineSTRUCTURE R scripts</a>, a facility for exploring the results when the GUI is unavailable.</li>
<li><a href="https://people.maths.bris.ac.uk/%7Emadjl/finestructure/globetrotter.html">GLOBETROTTER</a>, the admixture dating method based on ChromoPainter. Download from the <a href="https://people.maths.bris.ac.uk/%7Emadjl/finestructure/finestructure.html">Downloads</a> page.</li>
<li><a href="https://people.maths.bris.ac.uk/%7Emadjl/finestructure/admixture.html">AdmixturePainting</a>, A set of R tools to inmterpret the results of ADMIXTURE and STRUCTURE-like mixture models.</li>
<li><a href="https://people.maths.bris.ac.uk/%7Emadjl/finestructure/radpainter.html">RADpainter</a>, finestructure and ChromoPainter for RAD tag data used for non-model organisms.</li>
<li>Scripts to perform many types of conversion. Included in the main software download from the <a href="https://people.maths.bris.ac.uk/%7Emadjl/finestructure/finestructure.html">Downloads</a> page.</li>
</ul>
What this page is This page provides information about and downloads for <strong>methodology for Chromosome Painting</strong>. It is not a facility to analyse your genome. Sorry if you were misled by the punchy name!<br> About Chromosome Painting Painting is an efficient way of identifying important haplotype information from dense genotype data. It describes ancestry in an efficient way suitable for a range of further analyses, including population identification and admixture dating.</div><p>Address of the bookmark: <a href="http://paintmychromosomes.com/" rel="nofollow">http://paintmychromosomes.com/</a></p>]]></description>
	<dc:creator>Shruti Paniwala</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/31123/biodownloader</guid>
	<pubDate>Sat, 25 Feb 2017 17:52:33 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/31123/biodownloader</link>
	<title><![CDATA[BioDownloader]]></title>
	<description><![CDATA[<p><strong><em>BioDownloader</em></strong> is a program for downloading and/or updating files from ftp/http servers. The program has unique features that are specifically designed to deal with bioinformatics data files and servers:</p>
<ul>
<li>optimized to work with vast amount of data and very large file sets (~ 10,000 - 100,000).</li>
<li>allows the selective retrieval of only the required files (file masks, ls-lR parsing, recursive search, updates)</li>
<li>has a built-in repository containing the settings for the most common bioinformatics download needs</li>
<li>built-in wizard for batch post-processing of downloaded files (archive extraction, file conversion, etc.)</li>
<li>capable of performing multiple download or update tasks simultaneously</li>
</ul>
<p>BioDownloader has a built-in repository containing the settings for common bioinformatics file-synchronization needs, including the Protein Data Bank (PDB) and National Center for Biotechnology Information (NCBI) databases. It can post-process downloaded files, including archive extraction and file conversions.</p>
<p>http://dunbrack.fccc.edu/BioDownloader/</p><p>Address of the bookmark: <a href="http://dunbrack.fccc.edu/BioDownloader/" rel="nofollow">http://dunbrack.fccc.edu/BioDownloader/</a></p>]]></description>
	<dc:creator>Surabhi Chaudhary</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/31024/dagchainer-computing-chains-of-syntenic-genes-in-complete-genomes</guid>
	<pubDate>Fri, 17 Feb 2017 16:13:35 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/31024/dagchainer-computing-chains-of-syntenic-genes-in-complete-genomes</link>
	<title><![CDATA[DAGchainer: Computing Chains of Syntenic Genes in Complete Genomes]]></title>
	<description><![CDATA[<p>The DAGchainer software computes chains of syntenic genes found within complete genome sequences. As input, DAGchainer accepts a list of gene pairs with sequence homology along with their genome coordinates. Using a scoring function which accounts for the distance between neighboring genes on each DNA molecule and the BLAST E-value score between homologs, maximally scoring chains of ordered gene pairs are computed and reported. This algorithm can be used to mine large evolutionary conserved regions of genomes between two organisms. Alternatively, by examining colinear sets of homologous genes found within a single genome, segmental genome duplications can be revealed.</p>
<p>This software distribution includes both the DAGchainer utility and a Java-based graphical interface that allows the inputs and outputs to be navigated and interrogated dynamically.</p><p>Address of the bookmark: <a href="http://dagchainer.sourceforge.net/" rel="nofollow">http://dagchainer.sourceforge.net/</a></p>]]></description>
	<dc:creator>Abhimanyu Singh</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/31205/yasra-reference-based-assembler</guid>
	<pubDate>Wed, 01 Mar 2017 08:32:45 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/31205/yasra-reference-based-assembler</link>
	<title><![CDATA[YASRA: Reference based assembler]]></title>
	<description><![CDATA[<p>YASRA (Yet Another Short Read Assembler) performs comparative assembly of short reads using a reference genome, which can differ substantially from the genome being sequenced. Mapping reads to reference genomes makes use of LASTZ (Harris et al), a pairwise sequence aligner compatible with BLASTZ. Special scoring sets were derived to improve the performance, both in runtime and quality for 454 and Illumina sequence reads.</p>
<p>YASRA uses LASTZ (<a href="http://bx.psu.edu/miller_lab">http://bx.psu.edu/miller_lab</a> for released version and <a href="http://www.bx.psu.edu/%7Ersharris/lastz/newer">http://www.bx.psu.edu/~rsharris/lastz/newer</a> for newer version) for aligning the sequences to the reference genome. Please install LASTZ (the newest version on <a href="http://www.bx.psu.edu/%7Ersharris/lastz/newer">http://www.bx.psu.edu/~rsharris/lastz/newer</a>) and add the LASTZ binary in your executable/binary search path before installing YASRA.</p><p>Address of the bookmark: <a href="https://github.com/aakrosh/YASRA" rel="nofollow">https://github.com/aakrosh/YASRA</a></p>]]></description>
	<dc:creator>Abhimanyu Singh</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/32076/ngs-teaching-material</guid>
	<pubDate>Wed, 05 Apr 2017 04:29:06 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/32076/ngs-teaching-material</link>
	<title><![CDATA[NGS teaching material]]></title>
	<description><![CDATA[<p><span>High throughput sequencing (HTS) technologies are being applied to a wide range of important topics in biology. However, the analyses of non-model organisms, for which little previous sequence information is available, pose specific problems. This course addresses the specific strengths and weaknesses of alternative HTS technologies, the computational resources needed for HTS, and how to analyze non-model species using HTS. The course consists of a practical training module, HTS bioinformatics training, and lecturing/seminars of HTS approaches specifically targeting non-model organisms.</span></p><p>Address of the bookmark: <a href="http://marinetics.org/teaching/hts/Assembly.html" rel="nofollow">http://marinetics.org/teaching/hts/Assembly.html</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/32358/list-of-goi-approved-peer-reviewed-bioinformatics-and-computational-biology-journals</guid>
	<pubDate>Tue, 25 Apr 2017 05:03:27 -0500</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/32358/list-of-goi-approved-peer-reviewed-bioinformatics-and-computational-biology-journals</link>
	<title><![CDATA[List of GOI approved peer reviewed bioinformatics and computational biology journals]]></title>
	<description><![CDATA[<p>Unfortunately, we now live in a world where the integrity of peer-reviewed journals is being threatened by the rise of the academic version of fake news &ndash; something many call &ldquo;predatory publishing". &nbsp;Mostly in academic publishing world, "predatory open access publishing" is an exploitative open-access publishing business model that involves charging publication fees to authors without providing the editorial and publishing services associated with legitimate journals (open access or not).</p><p>Nearly 20% of the such journals have a flashy impact factor and quick publication time, which are quick give-aways. Interestingly, under contact address, some journal websites do not even provide any address to contact. All of this has led to the emergence of a new and dark market of deceptive publishers that exploit the concept of open access and provide channels for &ldquo;scientific journal&rdquo; publication with little or no peer review. For a fee, they will publish almost anything &ndash; even if the study was fatally flawed. And these journals provide a forum that can be used as a channel to publish fraudulent &ldquo;advocacy research.&rdquo; You can find list of certain such publishers at "Beall's List" http://beallslist.weebly.com/</p><p>Keeping all these in mind, Government of India (GOI) decided to approved certain bioinformatics and computational biology journals for your research publication.<br /> <br />Following are the list of GOI validated and peer reviewed bioinformatics and computational biology journals:</p><p><strong>NOTE:Each journal details are in following order Tittle\nSource\nSubject. </strong><br /><strong>Point to remember: The list of journals are NOT sorted in any ascending or descending order.</strong></p><p><em>If I missed any other GOI validated bioinformatics journal, then please report me in comment section.</em></p><p><strong>Open Bioinformatics Journal</strong> <br />Scopus <br />Computer Science; Engineering; Medicine</p><p><strong>PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS</strong> <br />WoS <br />BIOLOGY &amp; BIOCHEMISTRY</p><p><strong>Advances and Applications in Bioinformatics and Chemistry</strong><br />Scopus<br />Biochemistry, Genetics and Molecular Biology Chemistry; Computer Science</p><p><strong>Advances in Bioinformatics</strong><br />Scopus<br />Biochemistry, Genetics and Molecular Biology; Computer Science; Engineering</p><p><strong>Applied Bioinformatics</strong><br />Scopus<br />Agricultural and Biological Sciences; Computer Science</p><p><strong>BIOINFORMATICS</strong> <br />WoS &amp; Scopus <br />COMPUTER SCIENCE</p><p><strong>Bioinformatics and Biology Insights</strong> <br />Scopus<br />Biochemistry, Genetics and Molecular Biology; Computer Science; Mathematics</p><p><strong>BMC BIOINFORMATICS</strong> <br />WoS &amp; Scopus <br />COMPUTER SCIENCE</p><p><strong>BRIEFINGS IN BIOINFORMATICS</strong> <br />WoS &amp; Scopus <br />COMPUTER SCIENCE</p><p><strong>Computational systems bioinformatics / Life Sciences Society. Computational Systems Bioinformatics Conference</strong> <br />Scopus <br />Medicine</p><p><strong>Current Bioinformatics</strong> <br />WoS &amp; Scopus <br />COMPUTER SCIENCE</p><p><strong>Current Protocols in Bioinformatics</strong> <br />Scopus <br />Biochemistry, Genetics and Molecular Biology</p><p><strong>JOURNAL OF COMPUTATIONAL INTELLIGENCE IN BIOINFORMATICS</strong> <br />ICI <br />BIOLOGICAL SCIENCE</p><p><strong>Journal of integrative bioinformatics</strong> <br />Scopus <br />Medicine</p><p><strong>Journal of Proteomics and Bioinformatics</strong> <br />Scopus<br />Biochemistry, Genetics and Molecular Biology; Computer Science</p><p><strong>Mathematical Biology and Bioinformatics</strong> <br />Scopus <br />Engineering; Mathematics</p><p><strong>Trends in Bioinfprmatics</strong><br />Scopus <br />Computer Science</p><p><strong>Eurasip Journal on Bioinformatics and Systems Biology</strong> <br />Scopus<br />General; Computer Science; Mathematics; Medicine</p><p><strong>Evolutionary Bioinformatics</strong> <br />WoS &amp; Scopus <br />COMPUTER SCIENCE</p><p><strong>Genomics, Proteomics and Bioinformatics</strong> <br />Scopus<br />Biochemistry, Genetics and Molecular Biology;Mathematics</p><p><strong>IEEE/ACM Transactions on Computational Biology and Bioinformatics</strong> <br />Scopus<br />Biochemistry, Genetics and Molecular Biology;Mathematics</p><p><strong>IEEE-ACM Transactions on Computational Biology and Bioinformatics</strong> <br />WoS <br />COMPUTER SCIENCE</p><p><strong>International Journal of Bioinformatics Research and Application</strong><br />Scopus<br />Biochemistry, Genetics and Molecular Biology; Medicine, Health</p><p><strong>International Journal o f Data M ining and Bioinformatics</strong> <br />WoS &amp; Scopus <br />COMPUTER SCIENCE</p><p><strong>IPSJ Transactions on Bioinformatics</strong> <br />Scopus <br />Biochemistry, Genetics and Molecular Biology;Computer Science</p><p><strong>Journal of Bioinformatics and Computational Biology</strong> <br />WoS &amp; Scopus<br />COMPUTER SCIENCE</p><p><strong>Journal of Clinical Bioinformatics</strong> <br />Scopus <br />Medicine</p><p><strong>PLoS Computational Biology</strong> <br />WoS &amp; Scopus <br />BIOLOGY &amp; BIOCHEMISTRY</p><p><strong>Reviews in Computational Chemistry</strong> <br />WoS &amp; Scopus <br />CHEMISTRY</p><p><strong>RSC Theoretical and Computational Chemistry Series</strong><br />Scopus <br />Chemistry; Computer Science</p><p><strong>Annual Reports in Computational Chemistry</strong> <br />Scopus <br />Chemistry; Mathematics</p><p><strong>Computational and Structural Biotechnology Journal</strong> <br />Scopus<br />Biochemistry, Genetics and Molecular Biology; Computer Science</p><p><strong>Computational and Theoretical Chemistry</strong> <br />WoS &amp; Scopus <br />CHEMISTRY</p><p><strong>COMPUTATIONAL BIOLOGY AND CHEMISTRY</strong> <br />WoS &amp; Scopus<br />COMPUTER SCIENCE</p><p><strong>COMPUTATIONAL CHEMISTRY</strong> <br />WoS <br />CHEMISTRY</p><p><strong>Journal of Theoretical and Computational Chemistry</strong> <br />Scopus<br />Chemistry; Computer Science</p><p><strong>Theoretical and Computational Chemistry</strong> <br />Scopus <br />Chemistry</p><p><strong>Wiley Interdisciplinary Reviews: Computational Molecular Science</strong> <br />Scopus<br />Biochemistry, Genetics and Molecular Biology;Chemistry; Computer Science; Materials Science; Mathematics</p><p><strong>Wiley Interdisciplinary Reviews- Computational Molecular Science</strong> <br />WoS <br />CHEMISTRY</p><p><strong>Interdisciplinary sciences, computational life sciences</strong><br />Scopus<br />Medicine</p><p><strong>Interdisciplinary Sciences-Computational Life Science</strong><br />WoS<br />Biology and Biochemistry</p><p><strong>International Journal of Computational Biology and Drug Design</strong><br />Scopus<br />Computer Science; Pharmacology, Toxicology and Pharmaceutics</p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/32631/barrnap-bacterial-ribosomal-rna-predictor</guid>
	<pubDate>Fri, 12 May 2017 09:24:41 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/32631/barrnap-bacterial-ribosomal-rna-predictor</link>
	<title><![CDATA[Barrnap: Bacterial ribosomal RNA predictor]]></title>
	<description><![CDATA[<p>Barrnap predicts the location of ribosomal RNA genes in genomes. It supports bacteria (5S,23S,16S), archaea (5S,5.8S,23S,16S), mitochondria (12S,16S) and eukaryotes (5S,5.8S,28S,18S).</p>
<p>It takes FASTA DNA sequence as input, and write GFF3 as output. It uses the new NHMMER tool that comes with HMMER 3.1 for HMM searching in RNA:DNA style. NHMMER binaries for 64-bit Linux and Mac OS X are included and will be auto-detected. Multithreading is supported and one can expect roughly linear speed-ups with more CPUs.&nbsp;</p><p>Address of the bookmark: <a href="https://github.com/tseemann/barrnap" rel="nofollow">https://github.com/tseemann/barrnap</a></p>]]></description>
	<dc:creator>Abhimanyu Singh</dc:creator>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/32716/jrfsrf-project-assistant-ii-recruitment-in-national-agri-food-biotechnology-institute-nabi</guid>
  <pubDate>Mon, 15 May 2017 05:37:52 -0500</pubDate>
  <link></link>
  <title><![CDATA[JRF/SRF / Project Assistant-II recruitment in National Agri-Food Biotechnology Institute (NABI)]]></title>
  <description><![CDATA[
<p>National Agri-Food Biotechnology Institute<br />ADVT. No: 2017-Researcher (02)</p>

<p>JRF/SRF / Project Assistant-II recruitment in National Agri-Food Biotechnology Institute (NABI)</p>

<p>Essential Qualification: According to the DST (DST OM No.SR/S9/Z-09/2012 dated 21.10.2014) Post Graduate degree in basic science(M.Sc) in Bioinformatics/Computational Biology/Systems Biology/Information Technology with NET or Graduate degree in professional course with NET or Post Graduate Degree (M.Tech) in professional course in Bioinformatics/Computational Biology/Systems Biology/Information Technology. Desirable qualification/skills: 1) Should be proficient in programming in Perl/Python/R language etc. 2) Should have knowledge and skills for data mining in biological sequence database . sequence analysis tools/packages, NGS Analysis . 3) Should have knowledge and skills to work in linux environment and write shell scripts.</p>

<p>Age : 28 years</p>

<p>Hiring Process : Written-test<br />Job Role : Research/JRF/SRF<br />How to apply</p>

<p>Application should be sent to Administrative officer, National Agri-Food Biotechnology Institute, Knowledge City, Sector-81, Mohali so as to reach latest by 30.05.2017 before 5:30 pm.</p>

<p>More at http://www.nabi.res.in/Vacancies/NABI/ResearchFellowships/JRFSRFRA/2017/ADVT.%20No%202017Researcher%20(02)/ApplicationForm.pdf</p>
]]></description>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/pages/view/34814/bioinformatics-web-application-development-with-perl</guid>
	<pubDate>Tue, 26 Dec 2017 18:14:11 -0600</pubDate>
	<link>https://bioinformaticsonline.com/pages/view/34814/bioinformatics-web-application-development-with-perl</link>
	<title><![CDATA[Bioinformatics Web Application Development with Perl]]></title>
	<description><![CDATA[<div><p>Perl's second wave of adoption came from the growth of the world wide web. Dynamic web pages&mdash;the precursor to modern web applications&mdash;were easy to create with Perl and CGI. Thanks to Perl's ubiquity as a language for system administrators and its power to manipulate text, it was the default choice for web programming. Its presence everywhere made it popular and, in some ways, the duct tape of the Internet.</p><h4>Web Application Development</h4><p>The old days of CGI programs and the simple development style that represented seem clunky. Web pages have become web applications. Development has moved from generating static HTML to both client and server side programming, with rich client interfaces and powerful backends.</p><p>Perl is still well suited for developing modern web apps. The language grows more powerful and easier to use every year, the available libraries are wonderful and keep getting better, and the inventions and discoveries available in modern Perl are unsurpassed.</p><p>In particular, a modern Perl developer can do amazing things with modern Perl tools. If you still think of Perl web development as a&nbsp;<em>cgi-bin</em>&nbsp;directory full of messy scripts that spew warnings to STDERR, you're a decade out of date. Better yet, you can replace that mess piecemeal, thanks to the new tools and techniques of modern Perl. See, for example, the ever-growing list of technologies&nbsp;<a href="http://www.builtinperl.com/">Built in Perl</a>.</p><h4>Modern Perl Web Frameworks</h4><p>While the old wave of web development may have made the CGI.pm module central, modern Perl web programming follows a stricter separation of business logic, URL and request routing, and output. The days of slinging a string here, an array there, a Perl hash yonder, declaring every variable at the top of the program, and maybe making a subroutine are gone. The Perl world has seen the value of abstraction and ways to mechanize away boilerplate. Perl has dozens of frameworks and toolkits designed to make web development and deployment simpler.</p><p>Any of a dozen of these frameworks will help you do great things, but three in particular stand out. You can build web sites and web applications of tremendous value with all three. These are neither the only good possibilities (think of POE or Jifty or Continuity or...) nor the only mechanisms for web programming with Perl (see Mechanize or LWP or Mojo::UserAgent for more). Yet if you want three good options to choose between, start here.</p><h4>Catalyst</h4><p>The&nbsp;<a href="http://catalystframework.org/">Catalyst</a>&nbsp;framework is a flexible and powerful system for building small to large web apps. It uses the&nbsp;<a href="http://moose.perl.org/">Moose</a>&nbsp;object system to provide great APIs for extension and further development. It's the most mature of the modern top Perl web frameworks, yet it retains its flexibility and vibrancy. In particular, its plugin and extension ecosystem allows it to evolve to provide new and essential features.</p><p>Catalyst has embraced the Plack/PSGI standard for Perl web deployment and recent versions are exploring high-scalability, event-based request handling models.</p><h4>Dancer</h4><p>The&nbsp;<a href="http://perldancer.org/">Dancer</a>&nbsp;framework is deliberately minimal in syntax and scope, but it also has a vibrant plugin ecosystem. Dancer particularly excels for smaller sites and applications, though good programmers can build larger things with it.</p><p>The first version of Dancer was easy to use. Dancer 2 continues that ease while improving the internals and robustness of applications.</p><h4>Mojolicious</h4><p>The&nbsp;<a href="http://mojolicio.us/">Mojolicious</a>&nbsp;(Mojo) framework has a real-time design based on high performance event handling. Its focus is solving new and interesting problems in simple and effective ways, and the project has produced a lot of new code that does old things in better ways.</p><p>In particular, Mojolicious goes to great lengths to support new web standards, such as CSS 3, web sockets, and HTTP 2.</p><p>Where Catalyst embraces the CPAN fully, Mojolicious by design provides most of what an average app might need in a single download. It's still fully compatible with the CPAN, but the intention is to provide good working defaults in a package that's easy to start with. Mojo's fans are quick to praise it as fun to develop.</p><p>A modern Perl web developer should be familiar with at least one of these frameworks.</p><h4>Modern Perl Storage Mechanisms</h4><p>Perl's venerable&nbsp;<a href="http://search.cpan.org/perldoc?DBI">DBI</a>&nbsp;module has been the focal point of database access since its invention. Its design allows it to provide the same interface to huge relational databases and flat files alike through its DBD extension mechanism. Yet the DBI by itself isn't the be-all, end-all of data storage and access in Perl.</p><h4>DBIx::Class</h4><p><a href="http://search.cpan.org/perldoc?DBIx::Class">DBIx::Class</a>&nbsp;sits on top of DBI to provide an API to your database based on the concept of queries and results. This is often sufficient to remove all but the most complicated of SQL from your code, leaving you to manipulate your business models instead of the small details of how a relational database works. The power and maintainability you receive is well the small cost of the learning curve.</p><p>Even better, DBIC can manage (and even generate) your database schema for you.</p><p>Recent versions of DBIC have demonstrated that a well-written ORM can perform much better than even clever hand-written code. Because it builds on the Perl DBI, it scales everywhere from SQLite to PostgreSQL, MySQL, Oracle, and more.</p><h3>Rose::DB</h3><p>The lesser-known but no less powerful&nbsp;<a href="http://search.cpan.org/perldoc?Rose::DB::Object">Rose::DB::Object</a>&nbsp;builds on&nbsp;<a href="http://search.cpan.org/perldoc?Rose::DB">Rose::DB</a>&nbsp;to provide an object-relational mapper for Perl. While its high level features most directly compare to those of DBIx::Class, it's often measurably faster.</p><h4>NoSQL on the CPAN</h4><p>Of course the&nbsp;<a href="http://search.cpan.org/">CPAN</a>&nbsp;has modules for almost any NoSQL database or job queue or persistence mechanism you could name, and several you have never heard of. Everything you need is a quick CPAN or cpanm away!</p><h4>Modern Perl Deployment Strategies</h4><p>In the early days of the web, deploying a Perl web application meant putting one or more&nbsp;<em>.cgi</em>&nbsp;or&nbsp;<em>.pl</em>&nbsp;files in a special directory and hoping that your system administrator had everything configured correctly. The execution model was often slow and cumbersome, and accessing shared resources such as databases was often tricky.</p><p>Modern Perl has better choices. While deployment strategies are the source of many arguments, the return on your investment from learning the modern way is impressive.</p><h4>Plack/PSGI</h4><p>The PSGI specification (as exemplified by&nbsp;<a href="http://plackperl.org/">Plack</a>) describes a strategy for building Perl web apps independent of server and with the possibility to share custom processing behaviors.</p><p>In other words, it's a standard for writing Perl apps to take advantage of the huge ecosystem of Perl development available on the CPAN without tying yourself to a server like Apache, Apache 2, nginx, or anything else.</p><p>Any good modern Perl web framework (including those listed here) supports PSGI. Several deployment mechanisms exist to meet various business needs which also support PSGI. In particular, you can deploy the same application with a local testing server on your own machine as you can to your production server or servers without changing your application at all.</p><h4>mod_perl</h4><p>The older but still viable mod_perl Apache httpd module embeds Perl into the web server. This was the first widespread persistence mechanism for Perl web applications themselves and it's still popular to this day, though PSGI compliance is often the choice for new development. (PSGI handlers to use mod_perl as the backend are available.)</p><p>Modern Perl developers should familiarize themselves with PSGI and the wealth of available Plack middleware.</p><h4>Perl Web Development</h4><p>Of course no discussion of Perl web development would be complete without mentioning the strength of the CPAN. Almost any project will benefit from the wealth of freely available libraries built to solve real problems. These distributions run the gamut from full-blown web frameworks and content management systems to APIs for web services, development tools, testing systems, and interfaces to document formats and external resources.</p><p>For example, if you need to write a web service which accepts JSON data and produces Excel spreadsheets, you can glue together a few CPAN distributions and get the job done early. If you need to consume XML from a remote service and emit a PDF, you're in luck.</p><p>Perl's prowess as a general purpose programming language as well as its flexibility and power in managing text and gluing systems together make it a wonderful fit for web development. The community's adoption of modern Perl standards such as PSGI and Plack only enhance your power.</p><p>Web application development in Perl is still viable, and modern Perl tools and techniques and libraries make it more powerful and pleasant than ever.</p></div>]]></description>
	<dc:creator>Jit</dc:creator>
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