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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/30833?offset=30</link>
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	<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/30140/cutadapt</guid>
	<pubDate>Wed, 14 Dec 2016 09:59:52 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/30140/cutadapt</link>
	<title><![CDATA[Cutadapt]]></title>
	<description><![CDATA[<p>Cutadapt finds and removes adapter sequences, primers, poly-A tails and other types of unwanted sequence from your high-throughput sequencing reads.</p>
<p>Cutadapt helps with these trimming tasks by finding the adapter or primer sequences in an error-tolerant way. It can also modify and filter reads in various ways. Adapter sequences can contain IUPAC wildcard characters. Also, paired-end reads and even colorspace data is supported. If you want, you can also just demultiplex your input data, without removing adapter sequences at all.</p>
<p>Cutadapt comes with an extensive suite of automated tests and is available under the terms of the MIT license.</p>
<p>If you use cutadapt, please cite&nbsp;<a href="http://dx.doi.org/10.14806/ej.17.1.200">DOI:10.14806/ej.17.1.200</a>&nbsp;.</p>
<p>More at&nbsp;https://github.com/marcelm/cutadapt</p><p>Address of the bookmark: <a href="http://cutadapt.readthedocs.io/en/stable/guide.html" rel="nofollow">http://cutadapt.readthedocs.io/en/stable/guide.html</a></p>]]></description>
	<dc:creator>Bulbul</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/30168/gene-synteny-database</guid>
	<pubDate>Fri, 16 Dec 2016 11:09:39 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/30168/gene-synteny-database</link>
	<title><![CDATA[Gene Synteny Database]]></title>
	<description><![CDATA[<p>Comparative genomics remains a pivotal strategy to study the evolution of gene organization, and this primacy is reinforced by the growing number of full genome sequences available in public repositories. Despite this growth, bioinformatic tools available to visualize and compare genomes and to infer evolutionary events remain restricted to two or three genomes at a time, thus limiting the breadth and the nature of the question that can be investigated. Here we present Genomicus, a new synteny browser that can represent and compare unlimited numbers of genomes in a broad phylogenetic view. In addition, Genomicus includes reconstructed ancestral gene organization, thus greatly facilitating the interpretation of the data.</p>
<p><strong>Availability:</strong>&nbsp;Genomicus is freely available for online use at&nbsp;<a href="http://www.dyogen.ens.fr/genomicus" target="pmc_ext">http://www.dyogen.ens.fr/genomicus</a>&nbsp;while data can be downloaded at&nbsp;<a href="ftp://ftp.biologie.ens.fr/pub/dyogen/genomicus" target="pmc_ext">ftp://ftp.biologie.ens.fr/pub/dyogen/genomicus</a></p>
<p><strong>Contact:</strong>&nbsp;<a href="mailto:dev@null">rf.sne.eigoloib@crh</a></p><p>Address of the bookmark: <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853686/" rel="nofollow">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853686/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/30214/megamerge-a-tool-to-merge-assembled-contigs-long-reads-from-metagenomic-sequencing-runs</guid>
	<pubDate>Mon, 19 Dec 2016 09:42:15 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/30214/megamerge-a-tool-to-merge-assembled-contigs-long-reads-from-metagenomic-sequencing-runs</link>
	<title><![CDATA[MeGAMerge: A tool to merge assembled contigs, long reads from metagenomic sequencing runs]]></title>
	<description><![CDATA[<p>MeGAMerge</p>
<p>MeGAMerge (A tool to merge assembled contigs, long reads from metagenomic sequencing runs)</p>
<p>Description</p>
<p>MeGAMerge is a perl based wrapper/tool that can accept any number of sequence (FASTA) files containing assembled contigs of any length in Multi-FASTA format to produce an improved contig set based on OLC based assembly. All overlap parameters (Minimum Overlap Length, Identity, etc) are user-declarable at runtime. It is written to run on Linux.</p>
<p>Requirements:</p>
<p>You will need to have the following tools installed and in $PATH, or added to $binpath in the tool:</p>
<p>Newbler (specifically runAssembly)<br>Minimus2 (part of AMOS, also requires MUMmer)</p><p>Address of the bookmark: <a href="https://github.com/LANL-Bioinformatics/MeGAMerge" rel="nofollow">https://github.com/LANL-Bioinformatics/MeGAMerge</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/30355/meme-suite</guid>
	<pubDate>Fri, 23 Dec 2016 08:49:55 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/30355/meme-suite</link>
	<title><![CDATA[MEME suite]]></title>
	<description><![CDATA[<p>Motif based sequence analysis suits&nbsp;</p>
<p>The MEME Suite allows the biologist to discover novel motifs in collections of unaligned nucleotide or protein sequences, and to perform a wide variety of other motif-based analyses.</p>
<p>The MEME Suite supports motif-based analysis of DNA, RNA and protein sequences. It provides motif discovery algorithms using both probabilistic (MEME) and discrete models (MEME), which have complementary strengths. It also allows discovery of motifs with arbitrary insertions and deletions (GLAM2). In addition to motif discovery, the MEME Suite provides tools for scanning sequences for matches to motifs (FIMO, MAST and GLAM2Scan), scanning for clusters of motifs (MCAST), comparing motifs to known motifs (Tomtom), finding preferred spacings between motifs (SpaMo), predicting the biological roles of motifs (GOMo), measuring the positional enrichment of sequences for known motifs (CentriMo), and analyzing ChIP-seq and other large datasets (MEME-ChIP).</p>
<p>The MEME Suite is comprised of a collection of tools that work together, as shown below. Not all the tools are available as webservices, so to get the full power of the MEME Suite you will need to&nbsp;<a href="http://meme-suite.org/doc/download.html">download</a>&nbsp;and&nbsp;<a href="http://meme-suite.org/doc/install.html">install</a>&nbsp;a local copy of the software. To see what has changed recently you can peruse the&nbsp;<a href="http://meme-suite.org/doc/release-notes.html">release notes</a>.</p>
<p>http://meme-suite.org/</p><p>Address of the bookmark: <a href="http://meme-suite.org/" rel="nofollow">http://meme-suite.org/</a></p>]]></description>
	<dc:creator>Bulbul</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/30540/progressive-cactus</guid>
	<pubDate>Tue, 17 Jan 2017 03:40:06 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/30540/progressive-cactus</link>
	<title><![CDATA[Progressive Cactus]]></title>
	<description><![CDATA[<h1><em style="font-size: 12.8px; font-weight: normal;">v0.0 by Glenn Hickey (<a href="mailto:hickey@soe.ucsc.edu">hickey@soe.ucsc.edu</a>)</em></h1>
<p>Progressive Cactus is a whole-genome alignment package.</p>
<h3><a href="https://github.com/glennhickey/progressiveCactus#requirements"></a>Requirements</h3>
<ul>
<li>git</li>
<li>gcc 4.2 or newer</li>
<li>python 2.7</li>
<li>wget</li>
<li>64bit processor and build environment</li>
<li>150GB+ of memory on at least one machine when aligning mammal-sized genomes; less memory is needed for smaller genomes.</li>
<li>Parasol or SGE for cluster support.</li>
<li>750M disk space</li>
</ul>
<h3><a href="https://github.com/glennhickey/progressiveCactus#instructions"></a>Instructions</h3>
<p>IMPORTANT NOTE: Progressive Cactus does not presently support installation into paths that contain spaces. Until this is resolved, you can use a softlink as a workaround: ln -s "path with spaces" "installation path without spaces"</p>
<p>In the parent directory of where you want Progressive Cactus installed:</p>
<pre><code>git clone git://github.com/glennhickey/progressiveCactus.git
cd progressiveCactus
git pull
git submodule update --init
make
</code></pre>
<p>It is also convenient to add the location of&nbsp;<code>progressiveCactus/bin</code>&nbsp;to your PATH environment variable. In order to run the included tools (ex hal2maf) in the submodules/ directory structure, first source&nbsp;<code>progressiveCactus/environment</code>&nbsp;to load the installed environment.</p>
<p>If any errors occur during the build process, you are unlikely to be able to use the tool. Please submit a GitHub issue so we can help out: not only will you help yourself, but others who wish to use the tool as well.</p>
<p><em>Note that all dependencies are also built and included in the submodules/ directory. This increases the size and build time but greatly simplifies installation and version management. The installation does not create or modify any files outside the progressiveCactus/ directory.</em></p><p>Address of the bookmark: <a href="https://github.com/glennhickey/progressiveCactus" rel="nofollow">https://github.com/glennhickey/progressiveCactus</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/30971/hiveplot</guid>
	<pubDate>Thu, 16 Feb 2017 11:39:34 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/30971/hiveplot</link>
	<title><![CDATA[HivePlot]]></title>
	<description><![CDATA[<p>The&nbsp;<em>hive plot</em>&nbsp;is a rational visualization method for drawing networks. Nodes are mapped to and positioned on radially distributed linear axes &mdash; this mapping is based on network structural properties. Edges are drawn as curved links. Simple and interpretable.</p>
<p>The purpose of the hive plot is to establish a new baseline for visualization of large networks &mdash; a method that is both general and tunable and useful as a starting point in visually exploring network structure.</p>
<p>More at&nbsp;http://www.hiveplot.com/</p><p>Address of the bookmark: <a href="http://www.hiveplot.com/" rel="nofollow">http://www.hiveplot.com/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/31089/conpade-genome-assembly-ploidy-estimation-from-next-generation-sequencing-data</guid>
	<pubDate>Fri, 24 Feb 2017 04:55:41 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/31089/conpade-genome-assembly-ploidy-estimation-from-next-generation-sequencing-data</link>
	<title><![CDATA[ConPADE: Genome Assembly Ploidy Estimation from Next-Generation Sequencing Data]]></title>
	<description><![CDATA[<p><span>ConPADE (Contig Ploidy and Allele Dosage Estimation), a probabilistic method that estimates the ploidy of any given contig/scaffold based on its allele proportions. In the process, they report findings regarding errors in sequencing. The method can be used for whole genome shotgun (WGS) sequencing data. They also show applicability of the method for variant calling and allele dosage estimation. Results for simulated and real datasets are discussed and provide evidence that ConPADE performs well as long as enough sequencing coverage is available, or the true contig ploidy is low.&nbsp;</span></p>
<p><span>https://github.com/microsoftgenomics</span></p><p>Address of the bookmark: <a href="https://github.com/microsoftgenomics" rel="nofollow">https://github.com/microsoftgenomics</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/31295/mycc-accurate-binning-of-metagenomic-contigs-via-automated-clustering-sequences-using-information-of-genomic-signatures-and-marker-genes</guid>
	<pubDate>Fri, 03 Mar 2017 08:34:23 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/31295/mycc-accurate-binning-of-metagenomic-contigs-via-automated-clustering-sequences-using-information-of-genomic-signatures-and-marker-genes</link>
	<title><![CDATA[MyCC: Accurate binning of metagenomic contigs via automated clustering sequences using information of genomic signatures and marker genes]]></title>
	<description><![CDATA[<p><span>MyCC, an automated binning tool that combines genomic signatures, marker genes and optional contig coverages within one or multiple samples, in order to visualize the metagenomes and to identify the reconstructed genomic fragments.</span></p>
<p><span>More at&nbsp;http://www.nature.com/articles/srep24175</span></p><p>Address of the bookmark: <a href="https://sourceforge.net/projects/sb2nhri/files/MyCC/" rel="nofollow">https://sourceforge.net/projects/sb2nhri/files/MyCC/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/31351/maxbin-software-for-binning-assembled-metagenomic-sequences-based-on-an-expectation-maximization-algorithm</guid>
	<pubDate>Mon, 06 Mar 2017 04:03:38 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/31351/maxbin-software-for-binning-assembled-metagenomic-sequences-based-on-an-expectation-maximization-algorithm</link>
	<title><![CDATA[MaxBin: software for binning assembled metagenomic sequences based on an Expectation-Maximization algorithm.]]></title>
	<description><![CDATA[<p><span>MaxBin is software for binning assembled metagenomic sequences based on an Expectation-Maximization algorithm. Users can understand the underlying bins (genomes) of the microbes in their metagenomes by simply providing assembled metagenomic sequences and the reads coverage information or sequencing reads. For users' convenience MaxBin will report genome-related statistics, including estimated completeness, GC content and genome size in the binning summary page.</span><br><br><span>Users can use MEGAN or similar software on MaxBin bins to find the taxonomy of each bin after the binning process is finished.</span></p>
<p>https://academic.oup.com/bioinformatics/article/32/4/605/1744462/MaxBin-2-0-an-automated-binning-algorithm-to<br><br><span>The most recent version of MaxBin is 2.2, which supports the analysis of coassemblies of multiple samples. It is available at this JBEI downloads sites as well as&nbsp;</span><a href="https://sourceforge.net/projects/maxbin/" target="_blank">MaxBin</a><span>&nbsp;and&nbsp;</span><a href="https://sourceforge.net/projects/maxbin2/" target="_blank">MaxBin 2.0</a><span>&nbsp;sourceforge sites.</span></p><p>Address of the bookmark: <a href="http://downloads.jbei.org/data/microbial_communities/MaxBin/MaxBin.html" rel="nofollow">http://downloads.jbei.org/data/microbial_communities/MaxBin/MaxBin.html</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/32629/bienko-and-crosetto-labs</guid>
  <pubDate>Fri, 12 May 2017 07:42:15 -0500</pubDate>
  <link></link>
  <title><![CDATA[Bienko and Crosetto Labs]]></title>
  <description><![CDATA[
<p>We are two groups of scientists doing frontier research in quantitative biology and biomedicine. The Bienko group is interested in exploring the fundamental design principles controlling how DNA is packed in the eukaryotic nucleus and its relation to gene expression regulation. The Crosetto group engineers new molecular methods for single-cell and spatially resolved omic measurements of DNA, RNA, and proteins, with a strong focus on tumor heterogeneity. By sharing ideas and resources, we work synergistically towards a more quantitative understanding of life’s processes in healthy and diseased conditions.</p>

<p>https://bienkocrosettolabs.org/</p>
]]></description>
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