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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/31012?offset=470</link>
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	<description><![CDATA[]]></description>
	
	<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/36884/halc-high-throughput-algorithm-for-long-read-error-correction</guid>
	<pubDate>Fri, 08 Jun 2018 10:47:41 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/36884/halc-high-throughput-algorithm-for-long-read-error-correction</link>
	<title><![CDATA[HALC: High throughput algorithm for long read error correction]]></title>
	<description><![CDATA[HALC, a high throughput algorithm for long read error correction. HALC aligns the long reads to short read contigs from the same species with a relatively low identity requirement so that a long read region can be aligned to at least one contig region, including its true genome region’s repeats in the contigs sufficiently similar to it (similar repeat based alignment approach)

HALC was able to obtain 6.7-41.1% higher throughput than the existing algorithms while maintaining comparable accuracy. The HALC corrected long reads can thus result in 11.4-60.7% longer assembled contigs than the existing algorithms.<p>Address of the bookmark: <a href="https://github.com/lanl001/halc" rel="nofollow">https://github.com/lanl001/halc</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/22615/jrf-position-%E2%80%93-bioinformatics-department-aravind-medical-research-foundation-amrf-madurai</guid>
  <pubDate>Fri, 12 Jun 2015 05:42:12 -0500</pubDate>
  <link></link>
  <title><![CDATA[JRF Position – Bioinformatics Department, Aravind Medical Research Foundation (AMRF), Madurai.]]></title>
  <description><![CDATA[
<p>Applications are invited from eligible candidates for the post of Junior Research Fellow (JRF) to work at the Department of Bioinformatics, Aravind Medical Research Foundation in the following DST-SERB funded project “Clinical exome analysis pipeline for eye disease next-generation sequencing panel”.</p>

<p>Post: Junior Research Fellow (1 Position)</p>

<p>Duration: Three years</p>

<p>Qualification: First class in M.Sc/M.tech in Bioinformatics/Life Sciences/Biophysics/ Biostatistics/Bioengineering. Experience in Database development, NGS data analysis, Systems Biology and Structural Bioinformatics is desired. Preference will be given to the candidates with good computer programming skills in C, C++, R, Perl, PHP, Unix Scripting etc.</p>

<p>Selected candidates will be paid fellowship as per existing DST norms.</p>

<p>How to apply:</p>

<p>Candidates are requested to apply through one of the two modes given below<br />1. Online application – Click here to submit the online application https://docs.google.com/forms/d/16h2GLnQ-Ny-tLtlgfY3Bx3sCjeHJE30cfhJaDqW_uRs/viewform?c=0&amp;w=1<br />2. Application forms can be downloaded from here.https://docs.google.com/file/d/0BwwJEudQStxFWXdNWXl4NWtDaWc/edit<br /> Filled in application form should be sent by post to Dr. D. Bharanidharan, Department of Bioinformatics, Aravind Medical Research Foundation No 1, Anna Nagar Madurai – 625 020,</p>

<p>Candidates should apply by online or submit their applications by post on or before 15th June, 2015. Only Short listed candidates will be called for an interview. No TA/DA will be paid.</p>
]]></description>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/pages/view/28051/convert-ensembl-gtf-to-annotation-table-geneid-genesymbol-genewisechrlocation-geneclass-strand-raw</guid>
	<pubDate>Fri, 24 Jun 2016 18:08:49 -0500</pubDate>
	<link>https://bioinformaticsonline.com/pages/view/28051/convert-ensembl-gtf-to-annotation-table-geneid-genesymbol-genewisechrlocation-geneclass-strand-raw</link>
	<title><![CDATA[Convert EnsEMBL GTF to Annotation table (Geneid, GeneSymbol, GeneWiseChrLocation, GeneClass, Strand) Raw]]></title>
	<description><![CDATA[<p><strong>Bash Script source:</strong></p><p>https://gist.github.com/santhilalsubhash/367befcf5216be4b1fd9</p><p>&nbsp;</p><p><strong>Information</strong>:</p><p>This script converts EnsEMBL GTF (Ex:&nbsp;<a href="https://gist.githubusercontent.com/santhilalsubhash/1e7cca357e52a181dc25/raw/cfb803e07900a2baefbb6534f1299fd30cb57a29/sample.GTF">https://gist.githubusercontent.com/santhilalsubhash/1e7cca357e52a181dc25/raw/cfb803e07900a2baefbb6534f1299fd30cb57a29/sample.GTF</a>) file to annotation table format. It generated two files<br />1) Transcript wise chromosome location with information about transcripts (Ex:&nbsp;<a href="https://gist.githubusercontent.com/santhilalsubhash/c7dec516e0338503a4b6/raw/de0af1a39f0005c4ce7321c5ae57fc8b4a14c7f4/sample.GTF_enst_annotation.txt">https://gist.githubusercontent.com/santhilalsubhash/c7dec516e0338503a4b6/raw/de0af1a39f0005c4ce7321c5ae57fc8b4a14c7f4/sample.GTF_enst_annotation.txt</a>)<br />2) Gene wise chromosome location with information about genes (Ex:&nbsp;<a href="https://gist.githubusercontent.com/santhilalsubhash/c92006c5080f0333bec2/raw/d16e0b2440d73b09b486d3c9751cdb248a73fa0b/sample.GTF_ensg_annotation.txt">https://gist.githubusercontent.com/santhilalsubhash/c92006c5080f0333bec2/raw/d16e0b2440d73b09b486d3c9751cdb248a73fa0b/sample.GTF_ensg_annotation.txt</a>)</p><p>Note: You can download GTF files from&nbsp;<a href="http://www.ensembl.org/info/data/ftp/index.html">http://www.ensembl.org/info/data/ftp/index.html</a></p>]]></description>
	<dc:creator>EagleEye</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/pages/view/22571/pattern-matching-problem-solution-with-perl</guid>
	<pubDate>Tue, 09 Jun 2015 23:58:45 -0500</pubDate>
	<link>https://bioinformaticsonline.com/pages/view/22571/pattern-matching-problem-solution-with-perl</link>
	<title><![CDATA[Pattern Matching Problem Solution with Perl]]></title>
	<description><![CDATA[<p>Problem at http://rosalind.info/problems/1c/</p><p>#Find all occurrences of a pattern in a string.<br />#Given: Strings Pattern and Genome.<br />#Return: All starting positions in Genome where Pattern appears as a substring. Use 0-based indexing.<br /><br />use strict;<br />use warnings;<br /><br />my $string="GATATATGCATATACTT";<br />my $subStr="ATAT";<br />my $kmer=length($subStr);<br /><br />kmerMatch ($string, $subStr, $kmer);<br /><br />sub kmerMatch { #Check the exact matching kmers with sliding window<br />my ($string, $myStr, $kmer)=@_;<br />for (my $aa=0; $aa&lt;=(length($string)-$kmer); $aa++) {<br />&nbsp;&nbsp;&nbsp; my $myWin=substr&nbsp; $string, $aa,$kmer;<br />&nbsp;&nbsp;&nbsp; if ($myWin eq $myStr) {<br />&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; #print "$myWin eq $myStr\n";<br />&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; print $aa;<br />&nbsp;&nbsp;&nbsp; }<br />}<br />}</p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/37957/base-a-practical-de-novo-assembler-for-large-genomes-using-long-ngs-reads</guid>
	<pubDate>Fri, 19 Oct 2018 07:25:21 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/37957/base-a-practical-de-novo-assembler-for-large-genomes-using-long-ngs-reads</link>
	<title><![CDATA[BASE: a practical de novo assembler for large genomes using long NGS reads]]></title>
	<description><![CDATA[<p><span>new&nbsp;</span><em>de novo</em><span>&nbsp;assembler called BASE. It enhances the classic seed-extension approach by indexing the reads efficiently to generate adaptive seeds that have high probability to appear uniquely in the genome. Such seeds form the basis for BASE to build extension trees and then to use reverse validation to remove the branches based on read coverage and paired-end information, resulting in high-quality consensus sequences of reads sharing the seeds. Such consensus sequences are then extended to contigs.</span></p><p>Address of the bookmark: <a href="https://github.com/dhlbh/BASE" rel="nofollow">https://github.com/dhlbh/BASE</a></p>]]></description>
	<dc:creator>Rahul Nayak</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/22769/ensembl-27</guid>
	<pubDate>Tue, 16 Jun 2015 16:10:36 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/22769/ensembl-27</link>
	<title><![CDATA[Ensembl 27]]></title>
	<description><![CDATA[<h3>What is new?</h3><ul>
<li>Expansion of Protists and Fungi with hundreds of annotated genomes</li>
<li>Variation data for bread wheat, rice, <em>Aedes aegypti</em>, and <em>Ixodes scapularis</em></li>
<li>Whole genome alignments for <em>O. longistaminata</em> and <em>T. cacao</em></li>
<li>Non-coding RNA gene models in <a href="http://bacteria.ensembl.org">Bacteria</a></li>
<li>New assembly of tomato (version 2.50)</li>
<li>Full support for UCSC Track Hub format for hosting your own data in Ensembl</li>
</ul><p>More at http://www.ensembl.info/blog/2015/06/16/ensembl-genomes-release-27-is-out/</p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/38829/nquire-a-statistical-framework-for-ploidy-estimation-using-ngs-short-read-data</guid>
	<pubDate>Thu, 31 Jan 2019 05:12:19 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/38829/nquire-a-statistical-framework-for-ploidy-estimation-using-ngs-short-read-data</link>
	<title><![CDATA[nQuire: A statistical framework for ploidy estimation using NGS short-read data]]></title>
	<description><![CDATA[<p>nQuire implements a set of commands to estimate ploidy level of individuals from species, where recent polyploidization occurred and intraspecific ploidy variation is observed. Specifically, nQuire uses next-generation sequencing data to distinguish between diploids, triploids and tetraploids, on the basis of frequency distributions at variant sites where only two bases are segregating.</p>
<p>For more background see also the publication at&nbsp;<a href="https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-018-2128-z">BMC Bioinformatics</a>.</p>
<p>https://github.com/clwgg/nQuire</p><p>Address of the bookmark: <a href="https://github.com/clwgg/nQuire" rel="nofollow">https://github.com/clwgg/nQuire</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/22780/ra-bioinformatics-at-institution-centre-for-human-genetics-bangalore</guid>
  <pubDate>Wed, 17 Jun 2015 19:14:37 -0500</pubDate>
  <link></link>
  <title><![CDATA[RA Bioinformatics at Institution: Centre for Human Genetics,  Bangalore]]></title>
  <description><![CDATA[
<p>Institution: Centre for Human Genetics, <br />Bangalore <br />Discipline: Molecular Genetics of Human Disease Biology </p>

<p>Minimum qualification: MSc in any branch of life sciences</p>

<p>Applications are invited for the position of a Research Assistant in the Centre for Human Genetics, Bangalore. </p>

<p>The project involves identification of mutations in MPS (mucopolysaccharidosis) patients, and study of their predicted effects to understand how the mutations lead to disease. </p>

<p>Techniques used will be genomic DNA isolation, PCR, DNA sequencing and sequence analysis. Computational tools would also be used to analyse and interpret data. </p>

<p>Candidates may be assigned work in the ongoing project or in new ones. </p>

<p>The candidate who is selected and joins would acquire hands-on experience in research and the capability to conduct insightful research. </p>

<p>Candidates applying for the position should have an MSc in any branch of life sciences. Those with research experience in cell and molecular biology, and high NET/ GATE score would be preferred. </p>

<p>The successful applicant is expected to stay for at least one and a half years. </p>

<p>Please apply with CV to Sudha Srinivasan (sudha@ibab.ac.in), stating where you saw this ad.</p>
]]></description>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/40546/clincnv-detection-of-copy-number-changes-in-germlinetriosomatic-contexts-in-ngs-data</guid>
	<pubDate>Thu, 16 Jan 2020 23:16:02 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/40546/clincnv-detection-of-copy-number-changes-in-germlinetriosomatic-contexts-in-ngs-data</link>
	<title><![CDATA[ClinCNV: Detection of copy number changes in Germline/Trio/Somatic contexts in NGS data]]></title>
	<description><![CDATA[<p><span>ClinCNV detects CNVs in germline and somatic context in NGS data (targeted and whole-genome). We work in cohorts, so it makes sense to try&nbsp;</span><code>ClinCNV</code><span>&nbsp;if you have more than 10 samples (recommended amount - 40 since we estimate variances from the data). By "cohort" we mean samples sequenced with the same enrichment kit with approximately the same depth (ie 1x WGS and 30x WGS better be analysed in separate runs of ClinCNV). Of course it is better if your samples were sequenced within the same sequencing facility.</span></p><p>Address of the bookmark: <a href="https://github.com/imgag/ClinCNV" rel="nofollow">https://github.com/imgag/ClinCNV</a></p>]]></description>
	<dc:creator>Neel</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/41146/lofreq-a-sequence-quality-aware-ultra-sensitive-variant-caller-for-ngs-data</guid>
	<pubDate>Tue, 18 Feb 2020 03:24:22 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/41146/lofreq-a-sequence-quality-aware-ultra-sensitive-variant-caller-for-ngs-data</link>
	<title><![CDATA[LoFreq*: A sequence-quality aware, ultra-sensitive variant caller for NGS data]]></title>
	<description><![CDATA[<p>LoFreq* (i.e. LoFreq version 2) is a fast and sensitive variant-caller for inferring SNVs and indels from next-generation sequencing data. It makes full use of base-call qualities and other sources of errors inherent in sequencing (e.g. mapping or base/indel alignment uncertainty), which are usually ignored by other methods or only used for filtering.</p>
<p>https://github.com/CSB5/lofreq</p>
<p>http://csb5.github.io/lofreq/installation/</p>
<p>https://github.com/CSB5/lofreq/tree/master/dist</p><p>Address of the bookmark: <a href="http://csb5.github.io/lofreq/" rel="nofollow">http://csb5.github.io/lofreq/</a></p>]]></description>
	<dc:creator>BioStar</dc:creator>
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