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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/31087?offset=630</link>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/39017/macse-multiple-alignment-of-coding-sequences-accounting-for-frameshifts-and-stop-codons</guid>
	<pubDate>Mon, 18 Feb 2019 04:21:50 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/39017/macse-multiple-alignment-of-coding-sequences-accounting-for-frameshifts-and-stop-codons</link>
	<title><![CDATA[MACSE: Multiple Alignment of Coding SEquences Accounting for Frameshifts and Stop Codons]]></title>
	<description><![CDATA[<p>MACSE aligns coding NT sequences with respect to their AA translation while allowing NT sequences to contain multiple frameshifts and/or stop codons. MACSE is hence the first automatic solution to align protein-coding gene datasets containing non-functional sequences (pseudogenes) without disrupting the underlying codon structure. It has also proved useful in detecting undocumented frameshifts in public database sequences and in aligning next-generation sequencing reads/contigs against a reference coding sequence.</p>
<p>For further details about the underlying algorithm see the original publication:<br><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0022594" target="_new">MACSE: Multiple Alignment of Coding SEquences accounting for frameshifts and stop codons.<br>Vincent Ranwez, S&eacute;bastien Harispe, Fr&eacute;d&eacute;ric Delsuc, Emmanuel JP Douzery<br>PLoS One 2011, 6(9): e22594</a>.</p><p>Address of the bookmark: <a href="https://bioweb.supagro.inra.fr/macse/index.php?menu=releases" rel="nofollow">https://bioweb.supagro.inra.fr/macse/index.php?menu=releases</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/25147/pre-or-postdoctoral-research-fellowship-in-structural-bioinformatics-at-padova</guid>
  <pubDate>Thu, 05 Nov 2015 22:15:12 -0600</pubDate>
  <link></link>
  <title><![CDATA[Pre- or postdoctoral research fellowship in Structural Bioinformatics at Padova]]></title>
  <description><![CDATA[
<p>A research fellowship for a software developer is available at the BioComputing UP Laboratory, University of Padova (URL: http://protein.bio.unipd.it/).<br />A highly motivated and creative candidate is sought to work on structural bioinformatics. Specifically, the project entails the development of novel methods, tools and databases for the analysis of protein structures.</p>

<p>The BioComputing UP Laboratory, headed by Prof. Silvio Tosatto, is a dynamic group of a dozen people working on several aspects of prediction of protein structure &amp; function employing techniques at the intersection between biology, medicine, chemistry, physics &amp; computer science.<br />Our aim is to integrate the development of novel methods and their application to biologically relevant problems.</p>

<p>We are looking for candidates with a solid Bioinformatics background, programming experience (Python, C++ and/or Java) and good knowledge of molecular biology (protein structure/function). Good knowledge of statistics as well as experience in using database systems (MongoDB, MySQL and/or Postgres) is desirable. Candidates should have a degree with top marks, optionally hold a PhD, and be highly motivated to work on interdisciplinary research. Good knowledge of English, an open-minded spirit, being collaborative and creative are crucial.</p>

<p>The fellowship, which should start as soon as possible, is renewable and initially for one year. It will be commensurate to experience, can be extended depending on performance and may lead to a PhD degree. The successful candidate will be working full-time at the BioComputing UP Laboratory, University of Padova. Travel support for conferences and/or research visits abroad is provided.<br />To apply, please send your CV, with a motivation letter and brief description of your research background as well as the names of two (or more) references to: biocomp@bio.unipd.it. </p>

<p>Start date: As soon as possible</p>

<p>Duration: 1 year, renewable</p>

<p>Salary on grant: Commesurate to experience</p>

<p>Contact Person (Referent): Silvio Tosatto</p>

<p>Ref. E-Mail: biocomp@bio.unipd.it</p>

<p>Tel: +39 049 827 6269<br />Fax: +39 049 827 6260</p>

<p>Group Web Page: http://protein.bio.unipd.it/</p>
]]></description>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/43952/elastic-blast</guid>
	<pubDate>Tue, 06 Sep 2022 18:14:57 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/43952/elastic-blast</link>
	<title><![CDATA[Elastic BLAST !]]></title>
	<description><![CDATA[<p><a href="https://blast.ncbi.nlm.nih.gov/doc/elastic-blast/elasticblast.html?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=elasticblast-top3-20220823">ElasticBLAST</a>&nbsp;is a new way to&nbsp;<a href="https://blast.ncbi.nlm.nih.gov/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=elasticblast-top3-20220823">BLAST</a>&nbsp;large numbers of queries, faster and on the cloud. Here are the top three reasons you should use ElasticBLAST:</p>
<h6><strong><img src="https://i0.wp.com/ncbiinsights.ncbi.nlm.nih.gov/wp-content/uploads/2022/08/ElasticBLAST_Larger-e1659978198941.png?resize=150%2C120&amp;ssl=1" alt="" width="150" height="120" style="border: 0px;">1. ElasticBLAST can handle much LARGER queries!&nbsp;</strong></h6>
<p>ElasticBLAST can search query sets that have&nbsp;<em>hundreds to millions of sequences</em>&nbsp;and against BLAST databases of all sizes.</p>
<h6><span><img src="https://i0.wp.com/ncbiinsights.ncbi.nlm.nih.gov/wp-content/uploads/2022/08/ElasticBLAST_Faster.png?resize=150%2C120&amp;ssl=1" alt="" width="150" height="120" style="border: 0px;">2. ElasticBLAST is FASTER</span></h6>
<p>ElasticBLAST distributes your searches across multiple cloud instances to process them simultaneously. The ability to scale resources in this way allows you to process large numbers of queries in a shorter time than you could with BLAST+.</p>
<h6><img src="https://i0.wp.com/ncbiinsights.ncbi.nlm.nih.gov/wp-content/uploads/2022/08/ElasticBLAST_Easy.png?resize=150%2C120&amp;ssl=1" alt="" width="150" height="120" style="border: 0px;">3. ElasticBLAST is EASY to run on the cloud<strong><br></strong></h6>
<p>ElasticBLAST is easy to set up using our step-by-step instructions&nbsp;<span>(</span><a href="https://blast.ncbi.nlm.nih.gov/doc/elastic-blast/quickstart-aws.html?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=elasticblast-top3-20220823" target="_blank"><span><span>Amazon Web&nbsp;</span><span>Services (AWS)</span></span></a><span>,&nbsp;</span><a href="https://blast.ncbi.nlm.nih.gov/doc/elastic-blast/quickstart-gcp.html?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=elasticblast-top3-20220823" target="_blank"><span>Google Cloud Platform (GCP)</span></a><span><span>)</span>&nbsp;<span>and</span>&nbsp;<span>allows&nbsp;</span><span>you&nbsp;</span><span>to leverage the power of</span><span>&nbsp;the&nbsp;</span><span>cloud. Once configured, i</span><span>t</span>&nbsp;<span>manages the software and database installation, handles partitioning of the BLAST workload among the various instances, and deallocates cloud resources when the searches are done.</span></span></p>
<p><span><span>ElasticBLAST</span>&nbsp;<span>also&nbsp;</span><span>selects the instance (</span><span>i.e.,</span><span>&nbsp;machine) type for you based on database size. Of course, you can also choose the instance type manually if you prefer</span><span>.&nbsp;</span></span></p><p>Address of the bookmark: <a href="https://blast.ncbi.nlm.nih.gov/doc/elastic-blast/" rel="nofollow">https://blast.ncbi.nlm.nih.gov/doc/elastic-blast/</a></p>]]></description>
	<dc:creator>Abhi</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/26587/last</guid>
	<pubDate>Wed, 09 Mar 2016 14:27:01 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/26587/last</link>
	<title><![CDATA[LAST]]></title>
	<description><![CDATA[<p style="text-align: center;"><img src="http://last.cbrc.jp/lastwebfig.png" alt="sketch of  similar regions in sequences" style="border: 0px;"></p>
<p>LAST can:</p>
<ul>
<li>Handle <strong>big</strong> sequence data, e.g:
<ul>
<li>Compare two vertebrate genomes</li>
<li>Align billions of DNA reads to a genome</li>
</ul>
</li>
<li>Indicate the <a href="http://lastweb.cbrc.jp/about.html">reliability</a> of each aligned column.</li>
<li>Use sequence quality data <a href="http://nar.oxfordjournals.org/content/38/7/e100.abstract">properly</a>.</li>
<li>Compare DNA to proteins, with frameshifts.</li>
<li>Compare PSSMs to sequences</li>
<li>Calculate the likelihood of chance similarities between random sequences.</li>
<li>Do split and spliced alignment.</li>
<li><a href="http://last.cbrc.jp/doc/last-train.html">Train</a> alignment parameters for unusual kinds of sequence (e.g. nanopore).</li>
</ul><p>Address of the bookmark: <a href="http://last.cbrc.jp/" rel="nofollow">http://last.cbrc.jp/</a></p>]]></description>
	<dc:creator>Archana Malhotra</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/42965/nucl2vec-local-alignment-of-dna-sequences-using-distributed-vector-representation</guid>
	<pubDate>Tue, 16 Mar 2021 05:45:44 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/42965/nucl2vec-local-alignment-of-dna-sequences-using-distributed-vector-representation</link>
	<title><![CDATA[Nucl2Vec: Local alignment of DNA sequences using Distributed Vector Representation]]></title>
	<description><![CDATA[<p><span>We demonstrate a novel approach for</span><span>local alignment of DNA reads with respect to reference genome.</span><span>For this process we have used Skip-gram model for creating</span><span>encoding(Nucl2Vec) and k-nearest neighbor for the alignment.</span><span>With our new approach we have reduced computation cost for</span><span>local alignment , while achieving accuracy comparable to existing</span><span>defacto standard BWA-MEM tool.</span> </p>
<p><em>https://prakharg24.github.io/papers/401851.full.pdf</em></p><p>Address of the bookmark: <a href="https://prakharg24.github.io/papers/401851.full.pdf" rel="nofollow">https://prakharg24.github.io/papers/401851.full.pdf</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/25308/traineeship-at-biomedical-informatics-centre-pgimer-chandigarh</guid>
  <pubDate>Sun, 29 Nov 2015 03:04:27 -0600</pubDate>
  <link></link>
  <title><![CDATA[Traineeship at Biomedical Informatics Centre  PGIMER  Chandigarh]]></title>
  <description><![CDATA[
<p>Biomedical Informatics Centre</p>

<p>PGIMER</p>

<p>Chandigarh</p>

<p>invites application for a project dissertation program for students who have completed their first year of M.Sc. in Bioinformatics.</p>

<p>This is an exciting opportunity for Master's students to train in modern methods in Bioinformatics. The duration of the training will be four to six months, starting from January 2016.</p>

<p>Education: Pursuing M.Sc. Bioinformatics</p>

<p>Essential: Post graduate applicants should have completed their first year and should be in the third semester or first half of the second year.</p>

<p>Only students who are willing to spend a minimum period of 4 months to a maximum of six months, without any break, would be eligible for the program.</p>

<p>How to Apply: Candidates interested in the above project dissertation program should apply online. Send your CV, Scanned copy of letter of recommendation from Head of Institution along with Registration form in the given format should be sent to: info@bicpgi.org</p>

<p>Please mention clearly “Project dissertation &amp; your Name” in the Subject.</p>

<p>The last date for application is December 23, 2015</p>

<p>Note: Selected candidates may please note that the program is free of cost and would not provide any financial aid for transport and stay. Name of the selected candidates would be posted on the centre website by December 31, 2015.</p>

<p>Incomplete applications will be rejected.</p>

<p>For more information visit our website: http://bic-pgi.org/</p>
]]></description>
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<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/34562/harvest-a-suite-of-core-genome-alignment-and-visualization-tools</guid>
	<pubDate>Fri, 08 Dec 2017 07:16:03 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/34562/harvest-a-suite-of-core-genome-alignment-and-visualization-tools</link>
	<title><![CDATA[Harvest: a suite of core-genome alignment and visualization tools]]></title>
	<description><![CDATA[<p>Harvest is a suite of core-genome alignment and visualization tools for quickly analyzing thousands of intraspecific microbial genomes, including variant calls, recombination detection, and phylogenetic trees.</p>
<p><a href="https://harvest.readthedocs.io/en/latest/_images/screen.png"><img src="https://harvest.readthedocs.io/en/latest/_images/screen.png" alt="_images/screen.png" style="border: 0px;"></a><span></span></p>
<p><strong>Tools</strong></p>
<ul>
<li><a href="https://harvest.readthedocs.io/en/latest/content/parsnp.html">Parsnp</a>&nbsp;- Core-genome alignment and analysis</li>
<li><a href="https://harvest.readthedocs.io/en/latest/content/gingr.html">Gingr</a>&nbsp;- Interactive visualization of alignments, trees and variants</li>
<li><a href="https://harvest.readthedocs.io/en/latest/content/harvest-tools.html">HarvestTools</a>&nbsp;- Archiving and postprocessing</li>
<li></li>
</ul><p>Address of the bookmark: <a href="https://harvest.readthedocs.io/en/latest/" rel="nofollow">https://harvest.readthedocs.io/en/latest/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/25302/ra-bioinformatics-at-jamia-hamdard</guid>
  <pubDate>Sat, 28 Nov 2015 03:37:36 -0600</pubDate>
  <link></link>
  <title><![CDATA[RA Bioinformatics at Jamia Hamdard]]></title>
  <description><![CDATA[
<p>Research Associate, Bioinformatics Facility<br />Jamia Hamdard - New Delhi, Delhi<br />Research Associate, Bioinformatics Facility, Jamia Hamdard.<br />Emoluments: Rs. 22,000 + HRA 30%<br />Qualification: PhD or equivalent or having 3 years of research, teaching and design and development experience after M. Pharm./M.VSc./M.E./M.Tech. PhD in life sciences and related areas with experience in Bioinformatics may apply. Company Info.<br />Jamia Hamdard</p>

<p>Jamia Hamdard New Delhi - 110062 Additional Information States &amp; U.T State &amp; Union Territories Delhi How To Apply Apply Details<br />Last date of application: December 5, 2015 Web/Notification URL http://www.jamiahamdard.ac.in/</p>
]]></description>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/34920/xmatchview-smith-waterman-alignment-visualization</guid>
	<pubDate>Thu, 28 Dec 2017 09:00:58 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/34920/xmatchview-smith-waterman-alignment-visualization</link>
	<title><![CDATA[xmatchview: smith-waterman alignment visualization]]></title>
	<description><![CDATA[<p><span>xmatchview and xmatchview-conifer are imaging tools for comparing the synteny between DNA sequences. It allows users to align 2 DNA sequences in fasta format using cross_match and displays the alignment in a variety of image formats. xmatchview and xmatchview-conifer are written in python and run on linux and windows. They serve as visual tools for analyzing cross_match alignments. Cross_match (Green, P. (1994)&nbsp;</span><a href="http://www.phrap.org/">http://www.phrap.org</a><span>) uses an implementation of the Smith-Waterman algorithm for comparing DNA sequences that is sensitive.</span></p>
<p><span>http://www.bcgsc.ca/platform/bioinfo/software/xmatchview</span></p><p>Address of the bookmark: <a href="https://github.com/warrenlr/xmatchview" rel="nofollow">https://github.com/warrenlr/xmatchview</a></p>]]></description>
	<dc:creator>Rahul Nayak</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/36755/minialign-fast-and-accurate-alignment-tool-for-pacbio-and-nanopore-long-reads</guid>
	<pubDate>Thu, 24 May 2018 08:33:26 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/36755/minialign-fast-and-accurate-alignment-tool-for-pacbio-and-nanopore-long-reads</link>
	<title><![CDATA[minialign: fast and accurate alignment tool for PacBio and Nanopore long reads]]></title>
	<description><![CDATA[Minialign is a little bit fast and moderately accurate nucleotide sequence alignment tool designed for PacBio and Nanopore long reads. It is built on three key algorithms, minimizer-based index of the minimap overlapper, array-based seed chaining, and SIMD-parallel Smith-Waterman-Gotoh extension.<p>Address of the bookmark: <a href="https://github.com/ocxtal/minialign" rel="nofollow">https://github.com/ocxtal/minialign</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>

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