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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/31123?offset=1010</link>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/videolist/watch/11354/genomics-and-personalized-medicine</guid>
	<pubDate>Sun, 01 Jun 2014 23:38:42 -0500</pubDate>
	<link>https://bioinformaticsonline.com/videolist/watch/11354/genomics-and-personalized-medicine</link>
	<title><![CDATA[Genomics and Personalized Medicine]]></title>
	<description><![CDATA[<iframe width="" height="" src="https://www.youtube-nocookie.com/embed/pgHAXCMMcro" frameborder="0" allowfullscreen></iframe>(October 20, 2009) Michael Snyder, Professor of Genetics and Chair of the Department of Genetics at Stanford, discusses advances in gene sequencing, the impact of genomics on medicine, the potential for personalized medicine. and efforts at Stanford to further study these issues.

Stanford Mini Med School is a series arranged and directed by Stanford's School of Medicine, and presented by the Stanford Continuing Studies program. Featuring more than thirty distinguished, faculty, scientists and physicians from Stanford's medical school, the series offers students a dynamic introduction to the world of human biology, health and disease, and the groundbreaking changes taking place in medical research and health care.

Stanford University
http://www.stanford.edu

Stanford University School of Medicine
http://med.stanford.edu

Stanford Continuing Studies
http://continuingstudies.stanford.edu

Stanford University Channel on YouTube:
http://www.youtube.com/stanford]]></description>
	
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/38659/detail-annotation-of-genes</guid>
	<pubDate>Fri, 11 Jan 2019 05:23:33 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/38659/detail-annotation-of-genes</link>
	<title><![CDATA[Detail annotation of genes !]]></title>
	<description><![CDATA[<p>gene_info recalculated daily<br>---------------------------------------------------------------------------<br> tab-delimited<br> one line per GeneID<br> Column header line is the first line in the file.<br> Note: subsets of gene_info are available in the DATA/GENE_INFO<br> directory (described later)<br>---------------------------------------------------------------------------</p>
<p>tax_id:<br> the unique identifier provided by NCBI Taxonomy<br> for the species or strain/isolate</p>
<p>GeneID:<br> the unique identifier for a gene<br> ASN1: geneid</p>
<p>Symbol:<br> the default symbol for the gene<br> ASN1: gene-&gt;locus</p>
<p>LocusTag:<br> the LocusTag value<br> ASN1: gene-&gt;locus-tag</p>
<p>Synonyms:<br> bar-delimited set of unofficial symbols for the gene</p>
<p>dbXrefs:<br> bar-delimited set of identifiers in other databases<br> for this gene. The unit of the set is database:value.<br> Note that HGNC and MGI include 'HGNC' and 'MGI', respectively,<br> in the value part of their identifier. Consequently,<br> dbXrefs for these databases will appear like:<br> HGNC:HGNC:1100<br> This would be interpreted as database='HGNC', value='HGNC:1100'<br> Example for MGI:<br> MGI:MGI:104537<br> This would be interpreted as database='MGI', value='MGI:104537'</p>
<p>chromosome:<br> the chromosome on which this gene is placed.<br> for mitochondrial genomes, the value 'MT' is used.</p>
<p>map location:<br> the map location for this gene</p>
<p>description:<br> a descriptive name for this gene</p>
<p>type of gene:<br> the type assigned to the gene according to the list of options<br> provided in https://www.ncbi.nlm.nih.gov/IEB/ToolBox/CPP_DOC/lxr/source/src/objects/entrezgene/entrezgene.asn</p>
<p><br>Symbol from nomenclature authority:<br> when not '-', indicates that this symbol is from a<br> a nomenclature authority</p>
<p>Full name from nomenclature authority:<br> when not '-', indicates that this full name is from a<br> a nomenclature authority</p>
<p>Nomenclature status:<br> when not '-', indicates the status of the name from the <br> nomenclature authority (O for official, I for interim)</p>
<p>Other designations:<br> pipe-delimited set of some alternate descriptions that<br> have been assigned to a GeneID<br> '-' indicates none is being reported.</p>
<p>Modification date:<br> the last date a gene record was updated, in YYYYMMDD format</p>
<p>Feature type:<br> pipe-delimited set of annotated features and their classes or <br> controlled vocabularies, displayed as feature_type:feature_class <br> or feature_type:controlled_vocabulary, when appropriate; derived <br> from select feature annotations on RefSeq(s) associated with the <br> GeneID</p><p>Address of the bookmark: <a href="ftp://ftp.ncbi.nih.gov/gene/DATA/GENE_INFO/" rel="nofollow">ftp://ftp.ncbi.nih.gov/gene/DATA/GENE_INFO/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/11434/adhoc-bioinformatics-faculty-position-nit</guid>
  <pubDate>Tue, 03 Jun 2014 16:19:52 -0500</pubDate>
  <link></link>
  <title><![CDATA[Adhoc Bioinformatics Faculty Position @ NIT]]></title>
  <description><![CDATA[
<p>NATIONAL INSTITUTE OF TECHNOLOGY, DEPARTMENT OF BIOTECHNOLOGY, WARANGAL – 506 021, Andhra Pradesh</p>

<p>No.NITW/BT/2014/adhoc</p>

<p>APPLICATIONS ARE INVITED FOR THE APPOINTMENT OF ADHOC FACULTY ON CONTRACT BASIS IN THE DEAPARTMENT OF BIOTECHNOLOGY</p>

<p>Period of Contract: Initially the appointment is for one semester i.e., from July 2014 up to December 2014 only.</p>

<p>Essential Qualifications:</p>

<p>i) B. Tech or equivalent in Biotechnology/ Industrial Biotechnology/ Biochemical Engineering / Chemical Engg. Or M. Sc in Microbiology/ Botany/ Zoology/ Biochemistry/Biotechnology and ii) M. Tech or equivalent in Biotechnology/Industrial Biotechnology/Bioinformatics</p>

<p>Or</p>

<p>Integrated M. Tech in Biotechnology/Industrial Biotechnology/ Bioinformatics</p>

<p>Candidates must possess First class (60% aggregate marks or 6.5 CGPA) at B. Tech/ M. Sc and M. Tech.</p>

<p>Desirable: Ph. D Pay Package: All selected candidates shall be eligible for a consolidated pay of Rs.30, 000/- per month. Candidates with Ph. D shall be eligible for an additional amount of Rs.5, 000/- per month.</p>

<p>How to apply : Applications on plain paper with attested photocopies of certificate and bio data along with justification for eligibility should reach to the Head, Department of Biotechnology, National Institute of Technology, Warangal AP 506004 in the form of soft or hard copy on or before 21st June 2014 email : biotech_hod@nitw.ac.in</p>

<p>Intimation: No separate call letters will be sent to the candidates. All the eligible candidates will be notified in the institute web site on 23rd June 2014. All the eligible candidates are requested to report for the interview to the Head, Department of Biotechnology at 9:00 AM on 27th June 2014</p>

<p>Joining: Selected candidates will be informed and they are expected to join immediately.</p>

<p>Advertisement:</p>

<p>http://www.nitw.ac.in/nitw/announcements/2014/Bio-Adhoc%20Advt.%20May-2014.pdf</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/8417/conserved-domain-database-cdd-version-311-released</guid>
	<pubDate>Wed, 19 Feb 2014 15:02:40 -0600</pubDate>
	<link>https://bioinformaticsonline.com/news/view/8417/conserved-domain-database-cdd-version-311-released</link>
	<title><![CDATA[Conserved Domain Database (CDD) version 3.11 released]]></title>
	<description><![CDATA[<p>National Center for Biotechnology Information (NCBI) Conserved Domain Database (CDD) version 3.11 is now available with 596 new or updated NCBI-curated and 49,641 total domain models. The new version now contains the most recent Pfam release 27.</p><p><img src="http://www.ncbi.nlm.nih.gov/Structure/cdd/docs/images/np_081086_triangles_site_features_on_query_gi255958238_mouse_mutl1.png" alt="image" width="800" height="415" style="border: 0px; border: 0px;"></p><p>Updates to the Conserved Domain Database include:</p><ul>
<li>Position-specific score matrices (PSSMs) have been recomputed for many models in CDD, and frequency tables have been added to the PSSMs;</li>
</ul><ul>
<li>The search databases distributed as part of this release can now be used with the more recent versions of RPS-BLAST (BLAST release 2.2.28 and up) using composition-based scoring. This abolishes the need to mask out compositionally biased regions in query sequences;</li>
</ul><ul>
<li>Domain annotation displays in CD-Search, BATCH CD-Search, and other services now all use a uniform display style. A new display option in CD-Search and BATCH CD-Search provides “standard” results, in addition to “concise” and “full” results. “Standard” results will provide, for each region on the query sequence, the best0-scoring domain model (if any) from each of CDD’s database providers (Pfam, SMART, COG, TIGRFAMs, Protein Clusters, and the NCBI in-house curation project), but will suppress redundancy from within a single provider's results list.</li>
</ul><p>You can access CDD at the <a href="http://www.ncbi.nlm.nih.gov/cdd">Conserved Domains homepage</a> and find updated content on the <a href="ftp://ftp.ncbi.nih.gov/pub/mmdb/cdd">CDD FTP site</a>.</p><p>Reference:</p><p>NCBI Website</p>]]></description>
	<dc:creator>Shikha Logwani</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/pages/view/11735/search-shell-command-history</guid>
	<pubDate>Thu, 12 Jun 2014 17:43:34 -0500</pubDate>
	<link>https://bioinformaticsonline.com/pages/view/11735/search-shell-command-history</link>
	<title><![CDATA[Search Shell Command History]]></title>
	<description><![CDATA[<p>We use couple of hundreads of command in daily basis. Most of them are actually repeated several time. The question remain open how do I search old command history under bash shell and modify or reuse it? <br /><br />Now a days almost all modern shell allows you to search command history if enabled by user. Use history command to display the history list with line numbers. Lines listed with with a * have been modified by user.</p><p><br /><strong>Shell history search command</strong><br /><br />Type history at a shell prompt:<br />$ history</p><p>It will display the list of all used commandline history with an serial number.<br /><br />To search particular command, enter:<br />$ history | grep command-name<br />$ history | egrep -i 'scp|ssh|ftp'<br />Emacs Line-Edit Mode Command History Searching<br /><br />To get previous command containing string, hit [CTRL]+[r] followed by search string:<br /><br />(reverse-i-search): <br /><br />To get previous command, hit [CTRL]+[p]. You can also use up arrow key.<br /><br />CTRL-p<br /><br />To get next command, hit [CTRL]+[n]. You can also use down arrow key.<br /><br />CTRL-n<br /><br /></p><p><strong>fc command</strong></p><p>Apart from hostory command there are fc command to extract the command from history. The fc stands for either "find command" or "fix command.</p><p>For example list last 10 command, enter:<br />$ fc -l 10<br />To list commands 130 through 150, enter:<br />$ fc -l 130 150<br />To list all commands since the last command beginning with ssh, enter:<br />$ fc -l ssh<br />You can edit commands 1 through 5 using vi text editor, enter:<br />$ fc -e vi 1 5</p><p><strong>Delete command history</strong><br /><br />The -c option causes the history list to be cleared by deleting all of the entries:<br />$ history -c</p>]]></description>
	<dc:creator>Rahul Nayak</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/37545/ncbi-magic-blast</guid>
	<pubDate>Tue, 14 Aug 2018 18:11:11 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/37545/ncbi-magic-blast</link>
	<title><![CDATA[NCBI Magic-BLAST]]></title>
	<description><![CDATA[<p>Magic-BLAST is a tool for mapping large next-generation RNA or DNA sequencing runs against a whole genome or transcriptome. Each alignment optimizes a composite score, taking into account simultaneously the two reads of a pair, and in case of RNA-seq, locating the candidate introns and adding up the score of all exons. This is very different from other versions of BLAST, where each exon is scored as a separate hit and read-pairing is ignored.</p>
<p>Magic-BLAST incorporates within the NCBI BLAST code framework ideas developed in the NCBI Magic pipeline, in particular hit extensions by local walk and jump&nbsp;<a href="http://www.ncbi.nlm.nih.gov/pubmed/26109056">(http://www.ncbi.nlm.nih.gov/pubmed/26109056)</a>, and recursive clipping of mismatches near the edges of the reads, which avoids accumulating artefactual mismatches near splice sites and is needed to distinguish short indels from substitutions near the edges.</p>
<p>&nbsp;</p><p>Address of the bookmark: <a href="https://ncbi.github.io/magicblast/" rel="nofollow">https://ncbi.github.io/magicblast/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/11609/bioinformatician%E2%80%99s-pocket-reference</guid>
	<pubDate>Sun, 08 Jun 2014 09:56:58 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/11609/bioinformatician%E2%80%99s-pocket-reference</link>
	<title><![CDATA[Bioinformatician’s Pocket Reference !!]]></title>
	<description><![CDATA[<p><span>It is amusing how brain of bioinformaticians work! Learning a new programming language for days feels so much of fun that making 5 minute discussion with neighbours (unless under special circumstances!) in our own mother-tongue. Today every bioinformatician keeps more than few languages and core IT toolkits on their plate. It has become mandatory to be able to mould different code snippets to build our own custom workflows, and thus keeping syntax at our fingertips has become essential.Although Google is best way to get syntax problem solved, it is not a bad idea to keep reference sheets is our smartphones or stick out some printed sheets on the back of your door, in the old fashion way!!</span></p><p>Address of the bookmark: <a href="http://infoplatter.wordpress.com/2014/04/06/bioinformaticians-pocket-reference/" rel="nofollow">http://infoplatter.wordpress.com/2014/04/06/bioinformaticians-pocket-reference/</a></p>]]></description>
	<dc:creator>RAJESH DETROJA</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/41956/blast-on-docker-google-cloud-amazon-cloud</guid>
	<pubDate>Thu, 09 Jul 2020 02:57:11 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/41956/blast-on-docker-google-cloud-amazon-cloud</link>
	<title><![CDATA[Blast on Docker, Google Cloud, Amazon Cloud]]></title>
	<description><![CDATA[<p>As announced in a&nbsp;<a href="https://ncbiinsights.ncbi.nlm.nih.gov/2019/07/16/the-blast-programs-and-databases-are-available-in-docker-and-cloud-ready/" target="_blank">previous post</a>, we offer a&nbsp;<a href="https://www.docker.com/" target="_blank">Docker</a>&nbsp;version of NCBI BLAST+ that you can use locally or on the&nbsp;<a href="https://cloud.google.com/" target="_blank">Google Cloud</a>&nbsp;where we have pre-loaded BLAST databases.&nbsp; We are happy to announce that the same functionality is now available on the&nbsp;<a href="https://aws.amazon.com/" target="_blank">Amazon Cloud</a>.&nbsp; In addition, we now offer 23 different BLAST databases on each cloud platform.<span style="text-decoration: underline;"></span><span style="text-decoration: underline;"></span></p><p>As mentioned before, working with BLAST+ in Docker and the cloud has several advantages:<span style="text-decoration: underline;"></span><span style="text-decoration: underline;"></span></p><ul>
<li>Docker manages installation and maintenance of the BLAST programs and databases.<span style="text-decoration: underline;"></span><span style="text-decoration: underline;"></span></li>
<li>Docker makes it is easier to integrate BLAST with other tools in your pipelines.<span style="text-decoration: underline;"></span><span style="text-decoration: underline;"></span></li>
<li>NCBI BLAST databases are pre-loaded now on the both the&nbsp;<a href="https://cloud.google.com/" target="_blank" title="Follow link">Google Cloud</a>&nbsp;and&nbsp;<a href="https://aws.amazon.com/" target="_blank" title="Follow link">Amazon Cloud</a>, providing fast access.<span style="text-decoration: underline;"></span><span style="text-decoration: underline;"></span></li>
</ul><p>You can also use the BLAST+ Docker image on any Docker-enabled platform, such as another cloud platform or on your local computer.<span style="text-decoration: underline;"></span><span style="text-decoration: underline;"></span></p><p>See the&nbsp;&nbsp;<a href="https://github.com/ncbi/blast_plus_docs" target="_blank" title="Follow link">BLAST+ in the Cloud</a>&nbsp;and&nbsp;&nbsp;<a href="https://github.com/ncbi/docker/wiki/Getting-BLAST-databases" target="_blank" title="Follow link">database information</a>&nbsp;documentation to get started.<span style="text-decoration: underline;"></span><span style="text-decoration: underline;"></span></p><p>If you have any questions, please email us at&nbsp;blast-help@ncbi.nlm.nih.gov</p><p>Source:<span>Dave Arndt</span></p>]]></description>
	<dc:creator>LEGE</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/12218/assistant-professor-in-medical-bioinformatics</guid>
  <pubDate>Tue, 24 Jun 2014 01:46:36 -0500</pubDate>
  <link></link>
  <title><![CDATA[Assistant Professor in Medical Bioinformatics]]></title>
  <description><![CDATA[
<p>Advt. No : ME-I/A-IV/03/14<br />No.of Posts:01 (SC)<br />Pay Scale:<br />Pay Band of Rs.15600-39100 + Rs.6000/- GP +NPA @ 25% of Basic Pay +Learning Resource Allowance @ Rs.20,000/-P.A.+ Conveyance Allowance @ Rs. 1650/-P.M.+ Academic Allowance @ Rs.2500/- P.M. and other admissible allowances.<br />Qualifications:<br />Area of Specialization:-<br />Bioinformatics/Computational/Biology/Genomics/ Proteomics/ Structural Biology<br />1. Postgraduate qualification, e.g. Master’s Degree in Biotechnology/Bioinformatics/ Biophysics.<br />2. A Doctorate Degree of recognized University/Institute in a basic or allied Medical Science subject e.g. Medical Biotechnology/Biophysics. Bioinformatics/X-ray Crystallography/<br />Immunology/Structural Biology etc<br />Experience:<br />1.Minimum three years teaching and/or research experience in a recognized medical/research Institution in an allied medical subject after obtaining doctorate degree and preferably in Medical<br />Molecular Biology/ Biophysics/Structural Biology/Genomics and Clinical Proteomics/Computational Biology.<br />2. Minimum two publication with atleast one in international journal and atleast one as first author<br />Desirable:-<br />Consistently excellent scholastic/academic record, demonstrated ability to write grant proposal/(s) successfully, Post Doctoral training in a frontier area of medical Bioinformatics Research and of direct relevance to clinical diagnosis or patient care (preferably from a recognized top-ranking medical institution abroad)<br />Send your applications to O/O, Deputy Registrar, Recruitment &amp; Establishment Cell, University of Health Sciences, Rohtak by 08.7.2014<br />For more details,please visit website: http://pgimsrohtak.nic.in/2014%20AP%20Advt.pdf<br />Last Apply Date: 08 Jul 2014</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/44604/new-release-of-refseq</guid>
	<pubDate>Tue, 16 Jul 2024 10:09:21 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/44604/new-release-of-refseq</link>
	<title><![CDATA[New Release of RefSeq !]]></title>
	<description><![CDATA[<p>Check out RefSeq release 225, now available&nbsp;<a href="https://www.ncbi.nlm.nih.gov/refseq/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=refseq-release-225-20240715">online</a>&nbsp;and from the&nbsp;<a href="https://ftp.ncbi.nlm.nih.gov/refseq/release/">FTP</a>&nbsp;site. You can access RefSeq data through&nbsp;<a href="https://www.ncbi.nlm.nih.gov/datasets/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=refseq-release-225-20240715">NCBI Datasets</a>.</p><h5>What&rsquo;s included in this release?</h5><p>As of July 8, 2024, this full release incorporates genomic, transcript, and protein data containing:</p><ul>
<li><span>448,507,905 records</span></li>
<li><span>334,845,613 proteins</span></li>
<li><span>63,542,774 RNAs</span></li>
<li><span>Sequences from 152,668 organisms</span></li>
</ul><p>The release is provided in several directories as a complete dataset and also as divided by logical groupings.</p>]]></description>
	<dc:creator>Abhi</dc:creator>
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