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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/31156?offset=1530</link>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/38053/swgis-v20-a-seqword-genomic-island-sniffer</guid>
	<pubDate>Thu, 01 Nov 2018 12:35:52 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/38053/swgis-v20-a-seqword-genomic-island-sniffer</link>
	<title><![CDATA[swgis v2.0 : a seqword genomic island sniffer]]></title>
	<description><![CDATA[<p><strong>swgis v2.0</strong>&nbsp;is the modified version of the seqword genomic island sniffer. this version is specifically optimized for predicting genomic islands in eukaryotic genomes. swgis v2.0 was tested on several eukaryotic species of different lineages. all identified genomic islands were deposited in the&nbsp;<a href="http://eugi.bi.up.ac.za/" title="Go to EuGI database">eugi database</a>.</p>
<p><a href="http://eugi.bi.up.ac.za/download_swgis/swgisv2.0.zip" title="Download SWGIS v2.0">download swgis v2.0</a></p><p>Address of the bookmark: <a href="http://eugi.bi.up.ac.za/eugi_download_swgis.php" rel="nofollow">http://eugi.bi.up.ac.za/eugi_download_swgis.php</a></p>]]></description>
	<dc:creator>Abhimanyu Singh</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/videolist/watch/5380/04-informatics-approach-to-cancer-interview-with-dr-joel-saltz</guid>
	<pubDate>Mon, 07 Oct 2013 14:35:43 -0500</pubDate>
	<link>https://bioinformaticsonline.com/videolist/watch/5380/04-informatics-approach-to-cancer-interview-with-dr-joel-saltz</link>
	<title><![CDATA[04- Informatics Approach to Cancer - Interview with Dr. Joel Saltz]]></title>
	<description><![CDATA[<iframe width="" height="" src="https://www.youtube-nocookie.com/embed/8Kf5EP4LY7k" frameborder="0" allowfullscreen></iframe>For additional information visit http://www.cancerquest.org/joel-saltz-interview.

Dr. Joel Saltz is a Professor in the Departments of Pathology, Biostatistics and Bioinformatics, and Mathematics and Computer Science at
Emory University. Dr. Saltz's research on bioinformatics spans several disciplines.  One project involves applying computer analysis to medical imaging to yield better results for patients.  As an example, a computer program may able to help doctors detect small cancers in a CT scan or mammogram. 

In this interview segment, Dr. Saltz  discusses the informatics approach to cancer.

To learn more about cancer and watch additional interviews, please visit the CancerQuest website at http://www.cancerquest.org.]]></description>
	
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/38224/novograph-building-whole-genome-graphs-from-long-read-based-de-novo-assemblies</guid>
	<pubDate>Thu, 15 Nov 2018 12:48:30 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/38224/novograph-building-whole-genome-graphs-from-long-read-based-de-novo-assemblies</link>
	<title><![CDATA[NovoGraph: building whole genome graphs from long-read-based de novo assemblies]]></title>
	<description><![CDATA[<p><span>NovoGraph: building whole genome graphs from long-read-based de novo assemblies</span></p>
<p><span><span>An algorithmically novel approach to construct a genome graph representation of long-read-based&nbsp;</span><em>de novo</em><span>&nbsp;sequence assemblies. We then provide a proof of principle by creating a genome graph of seven ethnically-diverse human genomes.</span></span></p>
<p>&nbsp;</p>
<p>https://f1000research.com/articles/7-1391/v1</p><p>Address of the bookmark: <a href="https://github.com/NCBI-Hackathons/NovoGraph" rel="nofollow">https://github.com/NCBI-Hackathons/NovoGraph</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/videolist/watch/4959/evolution-and-cancer</guid>
	<pubDate>Fri, 27 Sep 2013 11:28:49 -0500</pubDate>
	<link>https://bioinformaticsonline.com/videolist/watch/4959/evolution-and-cancer</link>
	<title><![CDATA[Evolution and Cancer]]></title>
	<description><![CDATA[<iframe width="" height="" src="https://www.youtube-nocookie.com/embed/j3uKOcNwYBw" frameborder="0" allowfullscreen></iframe>Air date:  Wednesday, January 04, 2012, 3:00:00 PM
Time displayed is Eastern Time, Washington DC Local  
 
Category:  Wednesday Afternoon Lectures  
Description:  There is a broad consensus that cancer is the result of somatic cells having serially gained, by a series of mutations, the ability to grow independently, to recruit resources from the circulation and the stroma, to invade local tissues, and to found anatomically distant metastases, ultimately killing the host. From the point of view of the cancer-causing somatic cell population, this is evolution driven by mutation and selection. Genomics has resulted in a parallel consensus that the central functions of all eukaryotes are highly conserved, not only at the level of individual protein functions, but also complex biological pathways and systems. These ideas motivated a comparison between results of molecular genetic studies of experimental evolution in yeast and the molecular genetic phenomena associated with tumorigenesis and tumor progression. We find some very striking similarities, including recurring genomic rearrangements, alterations of the regulation of specific growth-promoting genes, population-genetic features that affect the fitness trajectories of growth rate variants in evolving populations, and physiological and metabolic similarities derived from the conservation of the basic plan of growth and cell multiplication among all eukaryotes. It is hoped that some of the insights from yeast will aid the interpretation of sequence changes found in tumors, especially in the urgent necessity to distinguish 'driver' from 'passenger' mutations." 

David Botstein's fundamental contributions to modern genetics include the development of genetic methods for understanding biological functions and the discovery of the functions of many yeast and bacterial genes. In 1980, Botstein and three colleagues proposed a method for mapping human genes that laid the groundwork for the Human Genome Project. The basic principle of the mapping scheme was to develop, by recombinant DNA techniques, random single-copy DNA probes capable of detecting DNA sequence polymorphisms when hybridized to restriction digests, or specific fragments, of an individual's DNA. The method was used in subsequent years to identify several human disease genes, such as Huntington's and BRCA1. Variations of this method enabled the sequencing phase of the Human Genome Project. 

In the 1990s Botstein, having moved to Stanford University School of Medicine, collaborated with Patrick O. Brown of Stanford in exploiting DNA microarrays to study genome-wide gene expression patterns in yeast and in human cancers. This required developing a new statistical method and graphical interface, widely used today to interpret genomic data. Botstein also has helped to create, with Michael Ashburner and Gerald Rubin, a bioinformatics initiative to unify the representation of gene and gene product attributes across all species, called Gene Ontology. He graduated from Harvard College and earned his doctorate from the University of Michigan. He worked at Massachusetts Institute of Technology from 1967 to 1988; served as vice president for science at Genentech from 1988 to 1990; chaired the Department of Genetics at the Stanford University School of Medicine from 1990 to 2003; and joined the Princeton University faculty in 2003. He has sat on numerous editorial boards and was the founding editor of Molecular Biology of the Cell. Among recent major awards, Bostein won the Peter Gruber Foundation Prize in Genetics in 2003, the Apple Science Innovator Award in 2008, and the Albany Medical Center Prize in 2010. 

The NIH Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide. 

For more information, visit: The NIH Director's Wednesday Afternoon Lecture Series  
Author:  Dr. David Botstein, Princeton University  
Runtime:  00:59:58  

Permanent link:  http://videocast.nih.gov/launch.asp?17046]]></description>
	
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/5253/pre-or-postdoctoral-research-fellowship-in-structural-bioinformatics-in-padova</guid>
  <pubDate>Wed, 02 Oct 2013 15:12:22 -0500</pubDate>
  <link></link>
  <title><![CDATA[Pre- or postdoctoral research fellowship in Structural Bioinformatics in Padova]]></title>
  <description><![CDATA[
<p>University of Padova (URL: http://protein.bio.unipd.it/)</p>

<p>A research fellowship is available at the BioComputing Laboratory, University of Padova (URL: http://protein.bio.unipd.it/). A highly motivated and creative candidate is sought to work on structural bioinformatics. Specifically, the project entails the development of novel methods, tools and databases for the analysis of protein structures. The BioComputing Laboratory is a group of a dozen people working on several aspects of prediction of protein structure &amp; function employing techniques at the intersection between biology, medicine, chemistry, physics &amp; computer science. Our aim is to integrate the development of novel methods and their application to biologically relevant problems. We are looking for candidates with a solid Bioinformatics background, programming experience (Python, Perl, C++ and/or Java) and good knowledge of molecular biology (protein structure/function, signalling pathways). Candidates should have a degree with top marks, optionally hold a PhD, and be highly motivated to work on interdisciplinary research. Good knowledge of English, an open-minded spirit, being collaborative and creative are crucial. The fellowship, which should start in late 2013, is initially for one year. It will be commensurate to experience, can be extended depending on performance and may lead to a PhD degree. The successful candidate will be located at the BioComputing Laboratory, University of Padova. Travel support for conferences and/or research visits abroad may be provided. To apply, please send your CV, a brief description of your research background and the names of two (or more) references to Prof. Silvio Tosatto (Email: silvio.tosatto@unipd.it). </p>

<p>Contact Person (Referent): Silvio Tosatto<br />Ref. E-Mail: silvio.tosatto@unipd.it<br />Tel: +39 049 827 6269<br />Fax: +39 049 827 6260<br />Group Web Page: http://protein.bio.unipd.it/</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/38672/ltr-retriever-accurately-identifies-and-annotates-ltr-retrotransposons-and-use-lai-to-evaluates-the-continuity-of-genome-assemblies</guid>
	<pubDate>Sun, 13 Jan 2019 07:14:31 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/38672/ltr-retriever-accurately-identifies-and-annotates-ltr-retrotransposons-and-use-lai-to-evaluates-the-continuity-of-genome-assemblies</link>
	<title><![CDATA[LTR_retriever: accurately identifies and annotates LTR retrotransposons and use LAI to evaluates the continuity of genome assemblies.]]></title>
	<description><![CDATA[<p>LTR_retriever is a command line program (in Perl) for accurate identification of LTR retrotransposons (LTR-RTs) from outputs of LTRharvest, LTR_FINDER, and/or MGEScan-LTR and generating non-redundant LTR-RT library for genome annotations.</p>
<p>By default, the program will generate whole-genome LTR-RT annotation and the LTR Assembly Index (LAI) for evaluations of the assembly continuity of the input genome. Users can also run LAI separately (see&nbsp;<code>Usage</code>).</p><p>Address of the bookmark: <a href="https://github.com/oushujun/LTR_retriever" rel="nofollow">https://github.com/oushujun/LTR_retriever</a></p>]]></description>
	<dc:creator>Neel</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/7217/contract-faculty-bioinformatics-at-maulana-azad-national-institute-of-technology</guid>
  <pubDate>Thu, 12 Dec 2013 20:46:52 -0600</pubDate>
  <link></link>
  <title><![CDATA[Contract Faculty-Bioinformatics at Maulana Azad National Institute of Technology]]></title>
  <description><![CDATA[
<p>Contract Faculty-Bioinformatics at Maulana Azad National Institute of Technology</p>

<p>Job Description:F.No.11/10(1)/929 Qualifications: Candidates should have Ph.D. degree. If Ph.D. candidates are not available at least Post Graduate degree with GATE/NET qualification is a must. Walk-in-Interview on 19.12.2013 at 2.30 P.M. to 5.30 P.M .. at Maulana Azad National Institute of Technology: Bhopal For more details,please visit website:http://www.manit.ac.in/manitbhopal/Year2013/Recruitment/Contract_faculty/contract%20faculty%202013-2014.pdf</p>

<p>For more @ http://www.manit.ac.in/manitbhopal/Year2013/Recruitment/Contract_faculty/contract%20faculty%202013-2014.pdf</p>

<p>Web address @ :http://www.manit.ac.in</p>
]]></description>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/5623/yau-group</guid>
  <pubDate>Tue, 15 Oct 2013 13:05:15 -0500</pubDate>
  <link></link>
  <title><![CDATA[Yau Group]]></title>
  <description><![CDATA[
<p>Yau Group are a new research group based at the Wellcome Trust Centre for Human Genetics and the Department of Statistics at the University of Oxford.</p>

<p>Yau Group develops statistical and computational methods for the analysis of genomic datasets with a particular interest in cancer sequencing applications and the use of Bayesian Statistics.</p>

<p>Yau Group are currently have projects in somatic mutation analysis of heterogeneous cancers, data fusion or integration techniques and single cell genomics.</p>

<p>More @ http://www.well.ox.ac.uk/~cyau/index.html</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/40416/5700-year-old-human-genome</guid>
	<pubDate>Thu, 19 Dec 2019 11:22:18 -0600</pubDate>
	<link>https://bioinformaticsonline.com/news/view/40416/5700-year-old-human-genome</link>
	<title><![CDATA[5700 year-old human genome !]]></title>
	<description><![CDATA[<p>A Landmark in genomics, scientists have done something that hasn't been done ever.</p><p>Scientists have reconstructed the genome of an ancient human who lived nearly 5,700 years ago in Southern Denmark from the birch pitch- an ancient tar-like substance.</p><p>By sequencing the sample, researchers not only discovered the ancient human DNA but also microbial DNA reflecting the oral microbiome of the person who chewed the pitch, along with plant and animal DNA that could be the recent<span> meal she might have consumed.</span></p><p><span style="font-size: 12.8px;">The DNA sample is comparable in quality to well-preserved teeth and skull bones. The DNA suggests that the chewer was a female, most likely with dark skin, dark brown hair and blue eyes.</span></p><div><p><a href="https://www.nature.com/articles/s41467-019-13549-9?fbclid=IwAR0FPk0Cl25YjHVdcfK4tqFhCsPx00SCSMUwlU6zNwMDNrKi1QynwtJKDfE" target="_blank">https://www.nature.com/articles/s41467-019-13549-9</a></p><p><img src="https://i.kinja-img.com/gawker-media/image/upload/c_scale,f_auto,fl_progressive,q_80,w_800/ykcvh491evenyvlrjb9r.jpg" width="800" height="450" alt="image" style="border: 0px;"></p><p>Artistic reconstruction. (Tom Bj&ouml;rklund)</p><p>More at&nbsp;<a href="https://gizmodo.com/scientists-reconstruct-lola-after-finding-her-dna-in-1840481633">https://gizmodo.com/scientists-reconstruct-lola-after-finding-her-dna-in-1840481633</a></p></div>]]></description>
	<dc:creator>Jit</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/7218/associate-professor-centre-for-bioinformatics-at-maharshi-dayanand-university-rohtak</guid>
  <pubDate>Thu, 12 Dec 2013 20:49:59 -0600</pubDate>
  <link></link>
  <title><![CDATA[Associate Professor - Centre for Bioinformatics at Maharshi Dayanand University, Rohtak]]></title>
  <description><![CDATA[
<p>ADVERTISEMENT No. PR-54/2013</p>

<p>No. of Posts and Specialization: 1(UR)</p>

<p>Educational Qualification:</p>

<p>(i) Good academic record with a Ph.D. Degree in the concerned /allied /relevant disciplines.</p>

<p>(ii) The Ph.D. Degree shall be a mandatory qualification for all candidates to be appointed as Associate Professor through direct recruitment.</p>

<p>(iii) A Master‟s Degree with at least 55% marks (or an equivalent grade in a point scale wherever grading system is followed).</p>

<p>(iv) A minimum of eight years of experience of teaching and /or research in an academic /research position equivalent to that of Assistant Professor in a University, College or Accredited Research Institution/Industry excluding the period of Ph.D research with evidence of published work and a minimum of 5 publications as books and /or research papers in refereed journals only/policy papers.</p>

<p>(v) Contribution to educations innovation, design of new curricula and courses and technology-mediated teaching learning process with evidence of having guided doctoral candidates and research students.</p>

<p>(vi) A minimum score as stipulated in the Academic Performance Indicator (API) based performance Based Appraisal System (PBAS), set out in this notification in as mentioned in the advertisement.</p>

<p>Send your application to the A.R (Estt.Teaching), M.D.University, Rohtak on or before December 23, 2013.</p>

<p>For more details: http://www.mdurohtak.ac.in/pdf/Notices_Pdf/new_notice/Teaching%20Vacancy%20%28ADVT.%20No.%20PR-54%20of%202013%29.pdf</p>

<p>Last Apply Date: 23 Dec 2013</p>
]]></description>
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