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<channel>
	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/31375?offset=830</link>
	<atom:link href="https://bioinformaticsonline.com/related/31375?offset=830" rel="self" type="application/rss+xml" />
	<description><![CDATA[]]></description>
	
	<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/37221/asplice-a-scalable-and-memory-efficient-algorithm-for-de-novo-transcriptome-assembly</guid>
	<pubDate>Tue, 03 Jul 2018 04:09:46 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/37221/asplice-a-scalable-and-memory-efficient-algorithm-for-de-novo-transcriptome-assembly</link>
	<title><![CDATA[ASplice: a scalable and memory-efficient algorithm for de novo transcriptome assembly]]></title>
	<description><![CDATA[With increased availability of de novo assembly algorithms, it is feasible to study entire transcriptomes of non-model organisms. While algorithms are available that are specifically designed for performing transcriptome assembly from high-throughput sequencing data, they are very memory-intensive, limiting their applications to small data sets with few libraries.

Texas A&amp;M University researchers develop a transcriptome assembly algorithm that recovers alternatively spliced isoforms and expression levels while utilizing as many RNA-Seq libraries as possible that contain hundreds of gigabases of data. New techniques are developed so that computations can be performed on a computing cluster with moderate amount of physical memory.

Availability – A software program that implements the algorithm is available at: http://faculty.cse.tamu.edu/shsze/asplice.

Sze SH, Pimsler ML, Tomberlin JK, Jones CD, Tarone AM. (2017) A scalable and memory-efficient algorithm for de novo transcriptome assembly of non-model organisms. BMC Genomics 18(Suppl 4):387.<p>Address of the bookmark: <a href="http://faculty.cse.tamu.edu/shsze/asplice/" rel="nofollow">http://faculty.cse.tamu.edu/shsze/asplice/</a></p>]]></description>
	<dc:creator>Rahul Nayak</dc:creator>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/31520/research-associate-openings-at-iasri-india</guid>
  <pubDate>Fri, 10 Mar 2017 03:53:03 -0600</pubDate>
  <link></link>
  <title><![CDATA[Research Associate openings at IASRI, India]]></title>
  <description><![CDATA[
<p>Research Associate (RA) Two (2) </p>

<p>Ph.D. in Bioinformatics/ Agricultural Statistics/ Statistics/ Computer Science/ Computer Application or equivalent or Master’s in Bioinformatics/ Agricultural Statistics/ Statistics/ Computer Science/ Computer Application or equivalent with 4 years or 5 years of Bachelor’s degree having 1st Division or 60% marks or equivalent overall grade point average, with at least two years of research experience as evidenced from fellowship/ associateship/ training/ other engagements. </p>

<p>Knowledge in System Biology/ Statistical and computational Genomics/ Bioinformatics <br />Knowledge in computer programming, LINUX OS. <br />Expertise in use of R/other Bioinformatics software </p>

<p>More at http://iasri.res.in/employment/2017/cabin_advertisement_RA_SRF_YP_Mar2017.pdf</p>

<p>Phenomics of Moisture Deficit Stress Tolerance and Nitrogen Use December 31, 2019 </p>

<p>Research Associate (RA) Two (2) </p>

<p>Ph.D. in Bioinformatics/ Agricultural Statistics/ Statistics/ Computer Science/ Computer Application or equivalent or System Administrator/ Computer expert for database development, development of phenome data bank and virtual phenomics facility, data archiving and Efficiency in Rice and Wheat-Phase II (Funded by National Agricultural Science Fund, ICAR) Master’s in Bioinformatics/ Agricultural Statistics/ Statistics/ Computer Science/ Computer Application or equivalent with 4 years or 5 years of Bachelor’s degree having 1st Division or 60% marks or equivalent overall grade point average, with at least two years of research experience as evidenced from fellowship/ associateship/ training/ other engagements. maintenance; Development of image analysis algorithms, APIs and IAPs. </p>

<p>Knowledge in System Biology/ Statistical and computational Genomics/ Bioinformatics <br />Knowledge of programming in LINUX/R/Perl/JAVA/PHP/JSP and use of various software &amp; tools. <br />December 31, 2019 </p>

<p>Ph.D. in Bioinformatics/ Agricultural Statistics/ Statistics/ Computer Science / Computer Application or equivalent or Master’s in Bioinformatics/ Agricultural Statistics/ Statistics/ Computer Science/ Computer Application or equivalent with 4 years or 5 years of Bachelor’s degree having 1st Division or 60% marks or equivalent overall grade point average, with at least two years of research experience as evidenced from fellowship/ associateship/ training/ other engagements. </p>

<p>Knowledge of Statistical and Computational Genomics/ Bioinformatics. <br />Knowledge of programming in LINUX/R/Perl/JAVA/PHP/JSP and use of various software &amp; tools. <br />March 31, 2020</p>
]]></description>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/31714/krona</guid>
	<pubDate>Wed, 22 Mar 2017 04:47:35 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/31714/krona</link>
	<title><![CDATA[Krona]]></title>
	<description><![CDATA[<p>Krona allows hierarchical data to be explored with zooming, multi-layered pie charts. Krona charts can be created using an <a href="https://github.com/marbl/Krona/wiki/ExcelTemplate">Excel template</a> or <a href="https://github.com/marbl/Krona/wiki/KronaTools">KronaTools</a>, which includes support for several bioinformatics tools and raw data formats. The interactive charts are self-contained and can be viewed with any modern web browser (see <a href="https://github.com/marbl/Krona/wiki/Browser%20support">Browser support</a>).</p>
<p><a href="http://marbl.github.io/Krona/img/screen_mgrast.png"><img src="https://camo.githubusercontent.com/27b71b1f1832523723c3d14dec764e7ad098438c/687474703a2f2f6d6172626c2e6769746875622e696f2f4b726f6e612f696d672f7468756d625f6d67726173742e706e67" width="210" height="167" alt="image" style="border: 0px;"></a></p><p>Address of the bookmark: <a href="https://github.com/marbl/Krona/wiki" rel="nofollow">https://github.com/marbl/Krona/wiki</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/32018/tmap-torrent-mapping-alignment-program-general-notes</guid>
	<pubDate>Sun, 02 Apr 2017 15:53:47 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/32018/tmap-torrent-mapping-alignment-program-general-notes</link>
	<title><![CDATA[TMAP - torrent mapping alignment program General Notes]]></title>
	<description><![CDATA[<p>TMAP - torrent mapping alignment program <a href="https://github.com/iontorrent/TS/tree/master/Analysis/TMAP#general-notes"></a>General Notes</p>
<p>TMAP is a fast and accurate alignment software for short and long nucleotide sequences produced by next-generation sequencing technologies.</p>
<ul>
<li>
<p>The latest TMAP is unsupported. To use a supported version, please see the TMAP version associated with a Torrent Suite release below.</p>
</li>
<li>
<p>Get the latest source code:</p>
<div>
<pre>git clone git://github.com/iontorrent/TMAP.git
 <span>cd</span> TMAP
 git submodule init
 git submodule update</pre>
</div>
</li>
</ul>
<p>https://github.com/iontorrent/TS/tree/master/Analysis/TMAP</p><p>Address of the bookmark: <a href="https://github.com/iontorrent/TS/tree/master/Analysis/TMAP" rel="nofollow">https://github.com/iontorrent/TS/tree/master/Analysis/TMAP</a></p>]]></description>
	<dc:creator>Poonam Mahapatra</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/38792/nxrepair-error-correction-in-de-novo-assemblies-using-nextera-mate-pair-reads</guid>
	<pubDate>Thu, 24 Jan 2019 10:35:12 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/38792/nxrepair-error-correction-in-de-novo-assemblies-using-nextera-mate-pair-reads</link>
	<title><![CDATA[NxRepair: error correction in de novo assemblies using Nextera Mate Pair Reads]]></title>
	<description><![CDATA[<p>NxRepair is a python module that automatically detects large structural errors in de novo assemblies using Nextera mate pair reads. The decector will break a contig at the site of an identified misassembly and will generate a new fasta file containing both the corrected contigs and the correct, unaffected contigs.</p>
<p>https://nxrepair.readthedocs.io/en/latest/tutorial.html</p>
<div>
<div>
<div id="js-repo-pjax-container">
<div>
<div>
<div id="readme">
<div>
<div>
<pre>nxrepair aligned_matepairs.bam assemblyfasta.fasta error_locations.csv new_fasta.fasta</pre>
</div>
</div>
</div>
</div>
</div>
</div>
</div>
</div>
<div>&nbsp;</div><p>Address of the bookmark: <a href="https://github.com/rebeccaroisin/nxrepair" rel="nofollow">https://github.com/rebeccaroisin/nxrepair</a></p>]]></description>
	<dc:creator>BioStar</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/39098/sda-long-read-sequence-and-assembly-of-segmental-duplications</guid>
	<pubDate>Tue, 05 Mar 2019 10:00:57 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/39098/sda-long-read-sequence-and-assembly-of-segmental-duplications</link>
	<title><![CDATA[SDA: Long-read sequence and assembly of segmental duplications]]></title>
	<description><![CDATA[<p><span><span>Segmental Duplication Assembler (SDA; https://github.com/mvollger/SDA) constructs graphs in which paralogous sequence variants define the nodes and long-read sequences provide attraction and repulsion edges, enabling the partition and assembly of long reads corresponding to distinct paralogs.<br></span></span></p>
<p><span><span>https://github.com/mvollger/SDA</span></span></p><p>Address of the bookmark: <a href="https://www.nature.com/articles/s41592-018-0236-3" rel="nofollow">https://www.nature.com/articles/s41592-018-0236-3</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/32358/list-of-goi-approved-peer-reviewed-bioinformatics-and-computational-biology-journals</guid>
	<pubDate>Tue, 25 Apr 2017 05:03:27 -0500</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/32358/list-of-goi-approved-peer-reviewed-bioinformatics-and-computational-biology-journals</link>
	<title><![CDATA[List of GOI approved peer reviewed bioinformatics and computational biology journals]]></title>
	<description><![CDATA[<p>Unfortunately, we now live in a world where the integrity of peer-reviewed journals is being threatened by the rise of the academic version of fake news &ndash; something many call &ldquo;predatory publishing". &nbsp;Mostly in academic publishing world, "predatory open access publishing" is an exploitative open-access publishing business model that involves charging publication fees to authors without providing the editorial and publishing services associated with legitimate journals (open access or not).</p><p>Nearly 20% of the such journals have a flashy impact factor and quick publication time, which are quick give-aways. Interestingly, under contact address, some journal websites do not even provide any address to contact. All of this has led to the emergence of a new and dark market of deceptive publishers that exploit the concept of open access and provide channels for &ldquo;scientific journal&rdquo; publication with little or no peer review. For a fee, they will publish almost anything &ndash; even if the study was fatally flawed. And these journals provide a forum that can be used as a channel to publish fraudulent &ldquo;advocacy research.&rdquo; You can find list of certain such publishers at "Beall's List" http://beallslist.weebly.com/</p><p>Keeping all these in mind, Government of India (GOI) decided to approved certain bioinformatics and computational biology journals for your research publication.<br /> <br />Following are the list of GOI validated and peer reviewed bioinformatics and computational biology journals:</p><p><strong>NOTE:Each journal details are in following order Tittle\nSource\nSubject. </strong><br /><strong>Point to remember: The list of journals are NOT sorted in any ascending or descending order.</strong></p><p><em>If I missed any other GOI validated bioinformatics journal, then please report me in comment section.</em></p><p><strong>Open Bioinformatics Journal</strong> <br />Scopus <br />Computer Science; Engineering; Medicine</p><p><strong>PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS</strong> <br />WoS <br />BIOLOGY &amp; BIOCHEMISTRY</p><p><strong>Advances and Applications in Bioinformatics and Chemistry</strong><br />Scopus<br />Biochemistry, Genetics and Molecular Biology Chemistry; Computer Science</p><p><strong>Advances in Bioinformatics</strong><br />Scopus<br />Biochemistry, Genetics and Molecular Biology; Computer Science; Engineering</p><p><strong>Applied Bioinformatics</strong><br />Scopus<br />Agricultural and Biological Sciences; Computer Science</p><p><strong>BIOINFORMATICS</strong> <br />WoS &amp; Scopus <br />COMPUTER SCIENCE</p><p><strong>Bioinformatics and Biology Insights</strong> <br />Scopus<br />Biochemistry, Genetics and Molecular Biology; Computer Science; Mathematics</p><p><strong>BMC BIOINFORMATICS</strong> <br />WoS &amp; Scopus <br />COMPUTER SCIENCE</p><p><strong>BRIEFINGS IN BIOINFORMATICS</strong> <br />WoS &amp; Scopus <br />COMPUTER SCIENCE</p><p><strong>Computational systems bioinformatics / Life Sciences Society. Computational Systems Bioinformatics Conference</strong> <br />Scopus <br />Medicine</p><p><strong>Current Bioinformatics</strong> <br />WoS &amp; Scopus <br />COMPUTER SCIENCE</p><p><strong>Current Protocols in Bioinformatics</strong> <br />Scopus <br />Biochemistry, Genetics and Molecular Biology</p><p><strong>JOURNAL OF COMPUTATIONAL INTELLIGENCE IN BIOINFORMATICS</strong> <br />ICI <br />BIOLOGICAL SCIENCE</p><p><strong>Journal of integrative bioinformatics</strong> <br />Scopus <br />Medicine</p><p><strong>Journal of Proteomics and Bioinformatics</strong> <br />Scopus<br />Biochemistry, Genetics and Molecular Biology; Computer Science</p><p><strong>Mathematical Biology and Bioinformatics</strong> <br />Scopus <br />Engineering; Mathematics</p><p><strong>Trends in Bioinfprmatics</strong><br />Scopus <br />Computer Science</p><p><strong>Eurasip Journal on Bioinformatics and Systems Biology</strong> <br />Scopus<br />General; Computer Science; Mathematics; Medicine</p><p><strong>Evolutionary Bioinformatics</strong> <br />WoS &amp; Scopus <br />COMPUTER SCIENCE</p><p><strong>Genomics, Proteomics and Bioinformatics</strong> <br />Scopus<br />Biochemistry, Genetics and Molecular Biology;Mathematics</p><p><strong>IEEE/ACM Transactions on Computational Biology and Bioinformatics</strong> <br />Scopus<br />Biochemistry, Genetics and Molecular Biology;Mathematics</p><p><strong>IEEE-ACM Transactions on Computational Biology and Bioinformatics</strong> <br />WoS <br />COMPUTER SCIENCE</p><p><strong>International Journal of Bioinformatics Research and Application</strong><br />Scopus<br />Biochemistry, Genetics and Molecular Biology; Medicine, Health</p><p><strong>International Journal o f Data M ining and Bioinformatics</strong> <br />WoS &amp; Scopus <br />COMPUTER SCIENCE</p><p><strong>IPSJ Transactions on Bioinformatics</strong> <br />Scopus <br />Biochemistry, Genetics and Molecular Biology;Computer Science</p><p><strong>Journal of Bioinformatics and Computational Biology</strong> <br />WoS &amp; Scopus<br />COMPUTER SCIENCE</p><p><strong>Journal of Clinical Bioinformatics</strong> <br />Scopus <br />Medicine</p><p><strong>PLoS Computational Biology</strong> <br />WoS &amp; Scopus <br />BIOLOGY &amp; BIOCHEMISTRY</p><p><strong>Reviews in Computational Chemistry</strong> <br />WoS &amp; Scopus <br />CHEMISTRY</p><p><strong>RSC Theoretical and Computational Chemistry Series</strong><br />Scopus <br />Chemistry; Computer Science</p><p><strong>Annual Reports in Computational Chemistry</strong> <br />Scopus <br />Chemistry; Mathematics</p><p><strong>Computational and Structural Biotechnology Journal</strong> <br />Scopus<br />Biochemistry, Genetics and Molecular Biology; Computer Science</p><p><strong>Computational and Theoretical Chemistry</strong> <br />WoS &amp; Scopus <br />CHEMISTRY</p><p><strong>COMPUTATIONAL BIOLOGY AND CHEMISTRY</strong> <br />WoS &amp; Scopus<br />COMPUTER SCIENCE</p><p><strong>COMPUTATIONAL CHEMISTRY</strong> <br />WoS <br />CHEMISTRY</p><p><strong>Journal of Theoretical and Computational Chemistry</strong> <br />Scopus<br />Chemistry; Computer Science</p><p><strong>Theoretical and Computational Chemistry</strong> <br />Scopus <br />Chemistry</p><p><strong>Wiley Interdisciplinary Reviews: Computational Molecular Science</strong> <br />Scopus<br />Biochemistry, Genetics and Molecular Biology;Chemistry; Computer Science; Materials Science; Mathematics</p><p><strong>Wiley Interdisciplinary Reviews- Computational Molecular Science</strong> <br />WoS <br />CHEMISTRY</p><p><strong>Interdisciplinary sciences, computational life sciences</strong><br />Scopus<br />Medicine</p><p><strong>Interdisciplinary Sciences-Computational Life Science</strong><br />WoS<br />Biology and Biochemistry</p><p><strong>International Journal of Computational Biology and Drug Design</strong><br />Scopus<br />Computer Science; Pharmacology, Toxicology and Pharmaceutics</p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/40099/contiguator</guid>
	<pubDate>Fri, 04 Oct 2019 01:27:58 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/40099/contiguator</link>
	<title><![CDATA[CONTIGuator !]]></title>
	<description><![CDATA[<p><span>CONTIGuator is a Python script for Linux environments whose purpose is to speed-up the bacterial genome assembly process and to obtain a first insight of the genome structure using the well-known artemis comparison tool (ACT).</span></p>
<p>&nbsp;</p><p>Address of the bookmark: <a href="https://sourceforge.net/projects/contiguator/" rel="nofollow">https://sourceforge.net/projects/contiguator/</a></p>]]></description>
	<dc:creator>BioStar</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/32631/barrnap-bacterial-ribosomal-rna-predictor</guid>
	<pubDate>Fri, 12 May 2017 09:24:41 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/32631/barrnap-bacterial-ribosomal-rna-predictor</link>
	<title><![CDATA[Barrnap: Bacterial ribosomal RNA predictor]]></title>
	<description><![CDATA[<p>Barrnap predicts the location of ribosomal RNA genes in genomes. It supports bacteria (5S,23S,16S), archaea (5S,5.8S,23S,16S), mitochondria (12S,16S) and eukaryotes (5S,5.8S,28S,18S).</p>
<p>It takes FASTA DNA sequence as input, and write GFF3 as output. It uses the new NHMMER tool that comes with HMMER 3.1 for HMM searching in RNA:DNA style. NHMMER binaries for 64-bit Linux and Mac OS X are included and will be auto-detected. Multithreading is supported and one can expect roughly linear speed-ups with more CPUs.&nbsp;</p><p>Address of the bookmark: <a href="https://github.com/tseemann/barrnap" rel="nofollow">https://github.com/tseemann/barrnap</a></p>]]></description>
	<dc:creator>Abhimanyu Singh</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/view/34362</guid>
	<pubDate>Thu, 16 Nov 2017 08:47:52 -0600</pubDate>
	<link>https://bioinformaticsonline.com/view/34362</link>
	<title><![CDATA[Tryst with a Bioinformatician # Dr Altan Kara]]></title>
	<description><![CDATA[<p style="text-align: justify;">&nbsp;</p><p style="text-align: justify;"><a href="http://bioinformaticsonline.com/profile/altan"><strong>Dr Altan Kara</strong></a> is a Bioinformatics specialist at the faculty of Gene Engineering and Biotechnology Institute at TUBITAK MAM Research Center. His research interest revolves around the cancer informatics and computational aided-drug design. I applaud Dr Altan for clearly setting out both his expectations of people that join his lab/university in addition to listing his responsibilities to his research members at TUBITAK MAM Research Instit&uuml;te. Hopefully, this interview will prove useful to others in the field, especially to those who are just starting their bioinformatics careers.</p><p style="text-align: justify;"><img src="https://photos-4.dropbox.com/t/2/AACboDtsdWXl6WLM8ijWiKVTxcLCdQaHuOxglRGVSIYqlQ/12/85115969/jpeg/32x32/1/_/1/2/altanLondon.JPG/EOfXoUIYmJ8CIAcoBw/HYCj2M1qYATfPnq3Lg_ETCtxjGzDJ34mwQP0ycTpMMM?size=1280x960&amp;size_mode=3" alt="image" width="720" height="720" style="border: 0px; border: 0px;"></p><p style="text-align: justify;">You can find out more about Dr Altan by visiting his (well documented) lab page (<a href="http://gmbe.mam.tubitak.gov.tr/en">http://gmbe.mam.tubitak.gov.tr/en</a>) and BOL page <a href="http://bioinformaticsonline.com/profile/altan">http://bioinformaticsonline.com/profile/altan</a> . And now, on to the BOL:&ldquo;Tryst with a Bioinformatician&rdquo; interview series ...</p><ul>
<li>
<p style="text-align: justify;"><strong>What push you to join Computational Biology/Bioinformatics?</strong></p>
</li>
</ul><p style="text-align: justify;">According to me, bioinformatics is the center of modern biological research and if a researcher wants to discover new biological insights by evaluating the globally produced biological data to derivate unified solutions for specific biological problems, learning bioinformatics is the only way to achieve this goal.</p><ul>
<li>
<p style="text-align: justify;"><strong>What fascinates you about Computational Biology/Bioinformatics?</strong></p>
</li>
</ul><p style="text-align: justify;">It's flexibility. As well known, there are highly diverse and complex biological questions are waiting to be enlightened and it's impossible to bring solutions to this diversity by using similar approaches. Thus, the employed method has to be unique for the targeted biological problem and by using bioinformatics tools this can be easily achieved.&nbsp;</p><ul>
<li>
<p style="text-align: justify;"><strong>What is the </strong><em><strong>one word</strong></em><strong> you would use to </strong><em><strong>describe yourself</strong></em><strong>?</strong></p>
</li>
</ul><p>Bioinformatician. :)</p><ul>
<li>
<p style="text-align: justify;"><strong>Can you please describe your research work in a nutshell for BOL users.</strong></p>
</li>
</ul><p style="text-align: justify;">At my current Institute, I am working in the field of cancer bioinformatics. Briefly, the overall aim of the project which I am working for (AKMARK (Project CODE:5153403)) is, applying a bioinformatics-supported genome, transcriptome, proteome, and metabolome analysis to reveal the molecular profile of the disease through an integrated approach, and to develop an early diagnosis and scanning kit based on this profile. Alterations in the gene, transcript, protein, and metabolite profiles between normal tissue, normal tissue adjoined to the tumor (reactive stroma), tumor tissue, lymph node metastasis, and blood samples taken from the same patient and the reflection of these changes in some other selected body fluids will be revealed within the scope of the project. The molecular structures involved in the development and progression of NSCLC will be determined and relations with the clinical, tumor-node-metastasis (TNM) staging and histology will be made. The development of a diagnostic kit for immediate clinical purposes and an electrochemical biosensor for quick on-site applications are targeted through the development of a number of antibody and aptamer formed against the most specific biomarker selected from the panel.</p><ul>
<li>
<p style="text-align: justify;"><strong>Is there anything else we should know about you and your research?</strong></p>
</li>
</ul><p style="text-align: justify;">Besides AKMARK, I am also in preparation of having a side project that aims for the development of a computational method to design inhibitors for prokaryotic two-component systems. In this project, I will be in collaboration with Prof. Maria Kontoyianni, SIUE: Southern Illinois University Edwardsville, School of Pharmacy.</p><ul>
<li>
<p style="text-align: justify;"><strong>What was your greatest scientific disappointment in life till now?</strong></p>
</li>
</ul><p>So far I do not experience any memorable scientific disappointment in my life. :)</p><ul>
<li>
<p style="text-align: justify;"><strong>What major research challenges and problems did you face yet? How did you handle them? </strong></p>
</li>
</ul><p style="text-align: justify;">The major challenge which I faced so far in my scientific career was predicting the interaction between the prokaryotic two-component proteins. To be able to accurately predict the interactions between these proteins, I create a meta-predictor by using a support vector machine. By using this technique I integrated six different protein-protein interaction methods in a way to cover disadvantage of one method with the advantage of another one. The meta-predictor which I developed during this work is accessible via <a href="http://metapred2cs.ibers.aber.ac.uk/">http://metapred2cs.ibers.aber.ac.uk/</a> and for more detailed information about the system the articles with the PMID IDs; PMID: 27378293 and PMID: 26384938 can be read.</p><ul>
<li>
<p style="text-align: justify;"><strong>What's your all-time favourite bioinformatics package, and why?</strong></p>
</li>
</ul><p style="text-align: justify;">For me, the best bioinformatics package is R/Bioconductor. The reason why I like this package is, it provides lots of useful tools for comprehensive analysis and comparison of high-throughput experimental data in an integrated manner and besides lots of the packages it provides, it is open source and also open for development. As a result, it provides strong and flexible ways to do science.</p><ul>
<li>
<p style="text-align: justify;"><strong>In bioinformatics, do you see yourself in which of the following roles-scientist, analyst, developer, engineer or pure academician?</strong></p>
</li>
</ul><p>Scientist / Developer.</p><ul>
<li>
<p style="text-align: justify;"><strong>What will you like to accomplish in next five years / ten years? </strong></p>
</li>
</ul><p style="text-align: justify;">For my current research, I would like to design a pipeline to automatically integrate and analyse omics data for cancer research which will be specifically aiming for biomarker and novel drug target discovery. In addition to this, I also like to develop another pipeline for prokaryotic TCS protein structure prediction and inhibitor design.</p><ul>
<li>
<p style="text-align: justify;"><strong>When you will be retired, what would you tell next generation bioinformaticians?</strong></p>
</li>
</ul><p style="text-align: justify;">Bioinformatics is not all about scripting and researchers who study in this field should never expect a tool to do their analyses for them. Besides computational skills, a bioinformatician must have a strong biological background in his/her research area which will allow them to understand if anything went wrong during their run by only looking at the results instead of just blindly trusting the output of the bioinformatics tools.</p><ul>
<li>
<p style="text-align: justify;"><strong>What you always miss in bioinformatics when you will no longer working in this field?</strong></p>
</li>
</ul><p style="text-align: justify;">Bioinformatics is open to doing multi-discipliner research with scientists all around the world. As a result, while I studying in this field I can interactively learn a lot from wide range research community. I think this is the one thing which I will miss the most.</p><ul>
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<p style="text-align: justify;"><strong>If there will be bioinformatics company owned by you in future, What are your company focus and aim?</strong></p>
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</ul><p style="text-align: justify;">With the increasing amount of data in databases, there is already a massive need for effective methods to eliminate the manipulated data and reach to clean/useful information. As days pass, the requirement of data mining will be the first step of any research project. For this reason, the major goal of my bioinformatics company will be developing effective tools to eliminate manipulated datasets and information that exist in the literature and provide trustworthy clean information/datasets for researchers.</p><ul>
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<p style="text-align: justify;"><strong>How much bioinformatics change in 2050, according to your wild imagination?</strong></p>
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</ul><p style="text-align: justify;">Bioinformatics is a field that constantly and dynamically changes. As the bioinformatics progress, new tools and methods become available and they provide a better application of existing methods or totally new methods that offer an alternative solution to various biological problems. A long with these updates, developers also provide easy to use GUIs for most of the tools. Considering this, if the field carries on developing like this, every single researcher with a strong biological background can be able to perform bioinformatics analyses by him/herself without needing a professional help. As a result, almost all of the bioinformaticians will be responsible just for development of new methods/tools.</p><ul>
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<p style="text-align: justify;"><strong>What would one piece of advice you give someone who's trying to reinvent themselves and enter into bioinformatics sector?</strong></p>
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</ul><p style="text-align: justify;">Bioinformatics is a wide field with a lot of career options. Thus, if a researcher likes to step into this field first he/she should be clear about the branch of the bioinformatics they like to study in. Following to this decision they should first learn at least one programing language and investigate the ways of how other researcher employed that language in their researches and WHY? A researcher, in this field, should never create and use copy paste scripts but always must understand WHY the other researcher worked in that way. Knowing the answer of this question is the only way to learn bioinformatics. Besides, a researcher in the field of bioinformatics (from any branch) must always be good about the environmental control. In other words, one should always easily control input output directories, modify files or directories, annotate and modify employed scripts during the research and should not allow any confusion during the different stages of the research. Finally, they should not blindly trust the output of a tool/software but do a benchmarking test for each of the tools which they decided to utilise in their research. In addition to this, even if the tools pass the benchmarking, researchers should have a good biological background in their field to tell if anything when wrong during the process by only looking the output(s) of the employed pipelines/packages/tools.&nbsp;&nbsp;</p><p style="text-align: justify;">&nbsp;</p>]]></description>
	<dc:creator>Jitendra Narayan</dc:creator>
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