BOL: Related items

Bioinformatics in Africa: Part5 - Nigeria

BioStar — Sat, 06 Feb 2021 21:13:47 -0600

Covenant University (CU)Ota:
Covenant University (with her enriching and growing stateoftheart laboratories in the area of science and technology, arts, business and social sciences) is presently the Best University in Nigeria (Private University category), based on the recent overall rating just concluded by the Nigeria University Commission (NUC). Recently, Covenant University has initiated the establishment of a Centre for Applied Biotech, BioInformatics and Microbiology (CBBM) to be situated at the University. The institute has been designed to be a PublicPrivate Partnership for a productive synergy b/w Academia, Industry and Government. The whole concept is still evolving and more details will be release soon. As regards CBBM, a dedicated computing lab is in plan, but even our computing capacity is presently enormous. In the department of Computer and Information Sciences, we have more than 250 Pentium 4 PCs set aside for teaching and research purposes. Furthermore, we have several moderate speed PCs at the Postgraduate research lab and our engineering departments and units. Our wet lab facilities is presently minimal (basic for teaching), the Centre requirement as it touches the wetlaboratories is also set to upgrade this to basic tools expected at an international centre of learning.

University of Ibadan (UIB)Ibadan:
There has been significant increase in the number of bioinformatics activities in Nigeria (and West Africa) since 2003 when the program was initiated by the West African Biotechnology Workshops Series (WABWS, http://www.wabw.org) at the University of Ibadan, Nigeria (in collaboration with the South African National Bioinformatics Institute (SANBI, http:/www.sanbi.ac.za). Workshops that were open to scientists from all African countries have seen a very high number of applications from scientists based in West Africa. The encouraging desire to acquire cuttingedge skills to computational process data and extract useful knowledge from genome projects led to the interest of the West African Biotechnology Workshops (WABW) to develop an agenda to address the bioinformatics skills gap among scientists in West Africa. An increased commitment from agencies like NEPAD would be required in the provision of infrastructure to establish and sustain regional and national networks.

University of Ilorin (UIL)Ilorin:
The University of Ilorin was established in 1976 by the Federal Government of Nigeria. Bioinformatics activities started at the University in February 2003 with the establishment of the West African Bioinformatics Research Initiative (WABRI). However, progress has been rather slow due to inadequate funding. We are mainly engaged in Bioinformatics training at the introductory level and proteomics studies on various species of malaria parasites. Recently, we became interested in comparative genome analysis of various species of Plasmodium and the comparison of chloroquine sensitive and chloroquine resistant strains of Plasmodium falciparum. Other activities and areas of interest can be seen on our website, http://www.wabri.org, although not all our proposed interests have been fully implemented due to our level of funding.

Training:
The University of Ilorin has introduced M.Sc. and Ph.D. programmes in Computer Science (with options in Bioinformatics). The programme is based in the Department of Computer Science and emphasis is on the development of algorithms to solve problems in bioinformatics. The Covenant University offers M.Sc. and Ph.D in Computer Science with option in Bioinformatics (Computational Biology). Furthermore, through affiliated departments, the CBBM is been design to award Diploma and Degree certificates in Biotechnology.

Web sites and links: http://www.covenantuniversity.com http://www.run.edu.ng http://www.uniben.edu http://www.wabri.org http://www.wabw.org http://www.unilorin.edu.ng http://www.wabri.org http://www.asopah.org

RA Bioinformatics at Sir Ganga Ram Hospital, New Delhi

Sun, 14 Mar 2021 10:40:18 -0500

Opportunities available at Institute of Medical Genetics & Genomics, Sir Ganga Ram Hospital, New Delhi.

1) Senior Research Fellow under ICMR Project: M.Sc. (Life Sciences) with 2 years of experience (preferable in the field of Bioinformatics) or MBBS Degree.

2) Research Associate under ICMR Project: . Ph.D.(Life Science/Biotechnology/Bioinformatics) or equivalent degree or having 3 years of research, teaching and design and development experience after M.Tech with at least one research paper in science Citation Indexed (SCI) Journal.
Work experience in the area of Human genomics/Next Generation Sequencing data analysis/Big data genomics would be preferred.
Application link:

https://sgrh.com/joblist

Post Code: 2023, 2024

Meraculous: Haplotype-sensitive Assembly of Highly Heterozygous genomes.

Jit — Wed, 20 Dec 2017 18:59:42 -0600

Meraculous is a whole genome assembler for Next Generation Sequencing data geared for large genomes. It is a hybrid k-mer/read-based assembler that capitalizes on the high accuracy of Illumina sequence by eschewing an explicit error correction step which we argue to be redundant with the assembly process. Meraculous achieves high performance with large datasets by utilizing lightweight data structures and multi-threaded parallelization, allowing to assemble human-sized genomes on commodity clusters in under a day. The process pipeline implements a highly transparent and portable model of job control and monitoring where different assembly stages can be executed and re-executed separately or in unison on a wide variety of architectures.

https://jgi.doe.gov/data-and-tools/meraculous/

https://arxiv.org/ftp/arxiv/papers/1703/1703.09852.pdf

Address of the bookmark: https://sourceforge.net/projects/meraculous20/

Nigerian Bioinformatics and Genomics Network (NBGN)

Tue, 31 Aug 2021 08:29:40 -0500

This is to announce the second official conference of the Nigerian Bioinformatics and Genomics Network (NBGN). October 11-13,2021 at Landmark University, Omu-Aran, Kwara State and Zoom ( conference link to be announced soon

#NBGN21

www.nbgn21conference.com

Flye: Fast and accurate de novo assembler for single molecule sequencing reads

Jit — Fri, 04 May 2018 19:16:22 -0500

Flye is a de novo assembler for long and noisy reads, such as those produced by PacBio and Oxford Nanopore Technologies. The algorithm uses an A-Bruijn graph to find the overlaps between reads and does not require them to be error-corrected. After the initial assembly, Flye performs an extra repeat classification and analysis step to improve the structural accuracy of the resulting sequence. The package also includes a polisher module, which produces the final assembly of high nucleotide-level quality.

Address of the bookmark: https://github.com/fenderglass/Flye

Interesting Bioinformatics Resources !

Abhi — Fri, 11 Nov 2022 06:30:46 -0600

1. a reproducible workflow. https://www.youtube.com/watch?v=s3JldKoA0zw This two minute video will change your mind on reproducible research

2. Parallel sequencing lives, or what makes large sequencing projects successful https://academic.oup.com/gigascience/article/6/11/gix100/4557140?login=false

3. Common-sense approaches to sharing tabular data alongside publication https://www.sciencedirect.com/science/article/pii/S2666389921002300

4. A Reproducible Data Analysis Workflow with R Markdown, Git, Make, and Docker https://psyarxiv.com/8xzqy/

5. Practical Computational Reproducibility in the Life Sciences https://www.cell.com/cell-systems/fulltext/S2405-4712(18)30140-6

6. A video by Dr.Keith A. Baggerly from MD Anderson [The Importance of Reproducible Research in High-Throughput Biology](https://www.youtube.com/watch?v=7gYIs7uYbMo) highly recommended.

7. Ten Simple Rules for Reproducible Computational Research http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1003285)

8. Good Enough Practices in Scientific Computing http://arxiv.org/abs/1609.00037

9. Best Practices for Scientific Computing https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1001745

10. A Quick Guide to Organizing Computational Biology Projects http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.100042 A must read for computational biologists!

11. Reproducibility of computational workflows is automated using continuous analysis https://www.nature.com/articles/nbt.3780

12. Five selfish reasons to work reproducibly https://genomebiology.biomedcentral.com/articles/10.1186/s13059-015-0850-7

Ranbow: a haplotype assembler for polyploid genomes

Jit — Fri, 01 Jun 2018 07:21:54 -0500

Ranbow is a haplotype assembler for polyploid genomes. It has been developed for the haplotype assembly of the hexaploid sweet potato genome, which is highly heterozygous. Ranbow can also be applied to other polyploid genomes. After a first phasing, Ranbow utilizes the assembled haplotypes to improve the accuracy of variant calling results and to infer the evolutionary history of the organism´s genome. Ranbow has three main modes of function: ranbow hap: for haplotyping ranbow eval: for evaluating of the assemble haplotypes by gold standard (long) reads ranbow phylo: for the phylogenetic analysis

Address of the bookmark: https://www.molgen.mpg.de/ranbow

Opportunity at McDermott Center Bioinformatics Lab

Sat, 01 Apr 2023 09:56:39 -0500

Our team, composed of experts from diverse backgrounds including genetics, cancer biology, computer science, bioinformatics, and microbiology, stays current with evolving bioinformatics techniques. We offer consulting, customized service, and collaboration opportunities. We suggest visiting us to discuss your experiment design and results, as we can tailor our assistance to meet your specific research goals.

https://labs.utsouthwestern.edu/bioinformatics-lab/positions

Bioinformatics Workshops !

Abhi — Wed, 31 Jul 2024 02:16:53 -0500

When delving into bioinformatics, having access to reliable resources is crucial for effective research and analysis. Key online resources include the National Center for Biotechnology Information (NCBI), which offers tools like BLAST for sequence alignment and comprehensive gene databases. For presentations and educational materials, exploring SlideShare for introductory and advanced bioinformatics topics can provide valuable insights and learning aids.

https://evomics.org/2024-workshop-on-genomics/

Address of the bookmark: https://evomics.org/2024-workshop-on-genomics/

Bioinformatician at QUB, UK

Tue, 01 Oct 2024 21:43:23 -0500

The post-holder will work under the direction of the Precision Medicine Centre of Excellence's (PMC) Bioinformatics lead and collaborate closely with the Scientific and Clinical leads. The primary responsibilities will be to develop, validate and maintain data analysis pipelines and algorithms that enable the comprehensive analysis of genomic information derived from cancer specimens, within the context of clinical studies. The PMC is an ISO 15189:2012 accredited medical laboratory (Ref 20634), providing an integrated cancer diagnostic and clinical research service that combines high throughput genomics and digital pathology (www.qub.ac.uk/research-centres/PMC).

About the person:

Essential criteria:

Hold or be about to obtain* a PhD in Computational biology, Bioinformatics, computing science or related subjects. (*must be obtained within 3 months of the closing date for the post) or MSc equivalent with at least 3 years' work experience in a relevant role.
Significant relevant research experience in genomics or work experience in a relevant technical/scientific role.
Significant experience in managing and analysing NGS data and other big data.
Experience in developing and maintaining analysis pipelines.
Experience working with Linux/UNIX environments.
Proficiency with python, bash, R and/or equivalent languages.
To be successful at shortlisting stage, please ensure you clearly evidence in your application how you meet the essential and, where applicable, desirable criteria listed in the Candidate Information document linked on our website.

More at https://hrwebapp.qub.ac.uk/tlive_webrecruitment/wrd/run/ETREC107GF.open